• Title/Summary/Keyword: medical Library

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Screening Peptides Binding Specifically to Colorectal Cancer Cells from a Phage Random Peptide Library

  • Wang, Jun-Jiang;Liu, Ying;Zheng, Yang;Liao, Kang-Xiong;Lin, Feng;Wu, Cheng-Tang;Cai, Guan-Fu;Yao, Xue-Qing
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.377-381
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    • 2012
  • The aim of this study was to screen for polypeptides binding specifically to LoVo human colorectal cancer cells using a phage-displayed peptide library as a targeting vector for colorectal cancer therapy. Human normal colorectal mucous epithelial cells were applied as absorber cells for subtraction biopanning with a c7c phage display peptide library. Positive phage clones were identified by enzyme-linked immunosorbent assay and immunofluorescence detection; amino acid sequences were deduced by DNA sequencing. After 3 rounds of screening, 5 of 20 phage clones screened positive, showing specific binding to LoVo cells and a conserved RPM motif. Specific peptides against colorectal cancer cells could be obtained from a phage display peptide library and may be used as potential vectors for targeting therapy for colorectal cancer.

A Study on the Webpage of Medical Libraries in Seoul (서울시 의학도서관의 웹페이지에 관한 연구)

  • Han, Hye-Young;Cho, Chan-Sik
    • Proceedings of the Korean Society for Information Management Conference
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    • 2004.08a
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    • pp.87-94
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    • 2004
  • 정보통신의 발달과 인터넷의 대중화로 인해 웹페이지 구축이 생활화됨에 따라 의학도서관에서도 웹페이지를 통한 효과적인 정보제공이 요구되고 있다. 이에 본 연구는 서울시 의학도서관 웹페이지를 대상으로 웹페이지 설계기준에 따라 구조와 내용을 분석하여 문제점을 살펴보고 활성화 방안을 마련하여, 웹페이지를 통한 효과적인 의학도서관의 정보서비스 제공에 기여하고자 한다.

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Interdisciplinary Collaborations in the Domain of Digital Libraries (디지털도서관 분야의 학제적 공동연구 분석에 관한 연구)

  • Chung, Eun-Kyung
    • Journal of the Korean Society for information Management
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    • v.28 no.2
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    • pp.37-51
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    • 2011
  • The domain of digital libraries is one of interdisciplinary fields since it contains various aspects of digital libraries. The main findings of digital library interdisciplinarity have been discussed in terms of contents, management and infrastructural technologies within the field of library and information science. The purpose of this study is to identify and widen the interdisciplinary structure of digital library domain by analyzing the collaborations from different disciplines. With 1,394 research articles of digital libraries from 1997 to 2010, the analysis of collaborations of authors from various disciplines was conducted. The results identified that three subject areas of authors such as Information science and library science, Computer science and Engineering were found as the centers to collaborate with various disciplines. In addition, sub-domains of digital library were recognized in terms of core digital library area, natural science area, medical related area and biology and medical area. The findings of this study depict the domain of digital libraries as a variety of subject areas since digital library domain is characterized with both research and practices.

Molecular Cloning, Identification and Characteristics of a Novel Isoform of Carbamyl Phosphate Synthetase I in Human Testis

  • Huo, Ran;Zhu, Hui;Lu, Li;Ying, Lanlan;Xu, Min;Xu, Zhiyang;Li, Jianmin;Zhou, Zuomin;Sha, Jiahao
    • BMB Reports
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    • v.38 no.1
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    • pp.28-33
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    • 2005
  • A gene coding a novel isoform of carbamyl phosphate synthetase I (CPS1) was cloned from a human testicular library. As shown by cDNA microarray hybridization, this gene was expressed at a higher level in human adult testes than in fetal testes. The full length of its cDNA was 3831 bp, with a 3149 bp open reading frame, encoding a 1050-amino-acid protein. The cDNA sequence was deposited in the GenBank (AY317138). Sequence analysis showed that it was homologous to the human CPS1 gene. The putative protein contained functional domains composing the intact large subunit of carbamoyl phosphate synthetase, thus indicated it has the capability of arginine biosynthesis. A multiple tissue expression profile showed high expression of this gene in human testis, suggesting the novel alternative splicing form of CPS1 may be correlated with human spermatogenesis.

A Study on the Effects of Domestic Medical Library Librarians' Awareness of the COVID-19 Situation on Information Services (국내 의학도서관 사서의 코로나19 상황 인식이 정보서비스에 미치는 영향에 관한 연구)

  • Kim, Tae Min;Kim, Hai Hin;Lee, Min Ji
    • Journal of the Korean Society for Library and Information Science
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    • v.55 no.3
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    • pp.303-319
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    • 2021
  • This study sought to find out the status of medical libraries in Korea that provide information services related to the Covid-19 situation, and how the librarian's perception of the Covid-19 situation, the main body of the library's information provision, affects the provision of related information services. For this purpose, we checked the website for Covid-19 information service. In order to understand the degree of awareness of Covid-19, Grunig's Situational Theory was applied to classify four types of librarians according to the degree of problem recognition, constraint recognition, and involvement recognition, and to analyze how the three perceptions affect Covid-19 related information services. As a result, only 25 out of 144 korean medical libraries provided information services related to Covid-19. The librarian, the main agent of the library's information provision, found that the problem recognition and involvement recognition in the Covid-19 situation were high, constraint recognition were low, and the level of information service was very active. And only constraint recognition has been shown to have a significant impact on providing Covid-19 related information services. Further research when future sources are available and follow-up research on how librarians' perceptions affect library operations are also proposed.

Systematic Review on the efficiency of prefilled syringe : To administer medication for cardiac arrest patient

  • Yoon, Byoung Gil;Park, Jung Hee;Kim, Young Seo
    • International Journal of Advanced Culture Technology
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    • v.10 no.4
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    • pp.23-244
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    • 2022
  • The Pulpose of this systematic review is aimed to establish the procedure of the injection with saftey and efficiency in the pre-hospital cardiac arrest patient performing the cardiopulmonary resuscitation (CPR), compared with traditional medication administration using Ampoule and medication administration with Prefilled Syringe. Databases were searched for CPR, heart arrest, resuscitation, Pre-filled Syringe, and Ampoule by the electronic data research including Pubmed, EMBASE and Cochran Library of Konyang University Library: 4 articles were selected by three co-authors using EndNote X20 and Covidence (Covidence.org) and were systematically reviewed. The Result of this study, the medication administration using Pre-fillled Syringe improves the safety of patients and Emergency medical workers by reducing the error in administration dose and administering the drug in safe than the medication adminisrtaion using Ampoule, also, contributes to the increment of survival rate of cardiac arrest and severe patients by decreasing the administration time that prevents the delay of medication administration.

Analysis on the Perception of the Service Quality and Satisfaction on the Electronic Journals of Medical Library Users (의학도서관 이용자의 전자저널 서비스품질 지각과 만족도 분석: K대학교 의과대학 교수 및 대학원생을 중심으로)

  • Cho, Hwa-Sun;Oh, Dong-Geun
    • Journal of Information Management
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    • v.42 no.4
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    • pp.23-37
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    • 2011
  • This study has surveyed the professors and graduate students of school of medicine at K university, to analyze the medical library users' service quality perceptions on electronic journals and their effects on the customer satisfaction. Two groups of faculty members and graduate students has statistically significant different perceptions on the service quality of electronic journals. Among four sub-dimensions of service quality, there are no statistically significant differences in the perceptions between two groups in convenience of use, accessability, and content resources, but there is significant differences in supportiveness between two groups. In the perceptions on the satisfaction and value, faculty group has significantly higher perceptions on both of them. The most influential dimension of the service quality of the electronic journal for the perception on the satisfaction is supportiveness followed by convenience of use and content resources. Moderating effect of value on service quality, its sub-dimensions, and satisfaction is not proved statistically.

A Structure of University Library for Ubiquitous Environment (유비쿼터스 환경에서의 대학도서관 조직)

  • Hong, Mi-Ra;Moon, Sung-Been
    • Journal of Information Management
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    • v.35 no.3
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    • pp.75-107
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    • 2004
  • The concept of "ubiquitous", which has been recently discussed in several industries, implies accessing a network using a computer from anywhere at anytime. The ubiquitous technology has been widely researched for distribution, construction, and medical treatments. Now, it has extended its application to libraries. The ubiquitous technology currently applied to a number of national libraries calls for a systematic study of an ubiquitous library. This thesis aims at presenting a model of introducing the ubiquitous technology to university libraries.