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The factors associated with Vitamin D deficiency in community dwelling elderly in Korea

  • Kim, Sun Hea;Oh, Jung Eun;Song, Dong Won;Cho, Choo Yon;Hong, Sung Ho;Cho, Yong Jin;Yoo, Byung Wook;Shin, Kyung Suk;Joe, Hyun;Shin, Hwang Sik;Son, Doo Yong
    • Nutrition Research and Practice
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    • v.12 no.5
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    • pp.387-395
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    • 2018
  • BACKGROUND/OBJECTIVE: Recent studies showed vitamin D deficiency is linked to chronic diseases in addition to skeletal metabolism which could threaten the elderly. We analyzed health conditions and socio-demographic factors associated with vitamin D deficiency in community dwelling people aged 65 years and older. SUBJECTS/METHOD: Data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2010 to 2012 were obtained. A total of 2,687 subjects aged 65 years and older were participated. The cutoff value of the Vitamin D deficiency was considered as serum 25-hydroxyvitamin D [25(OH)D] ${\leq}20ng/mL$ (50 nmol/L). RESULTS: The overall prevalence rate of vitamin D deficiency in the elderly was 62.1%. The factors such as female, obesity, metabolic syndrome, current smoker, and skipping breakfast were positively associated with vitamin D deficiency, but high intensity of physical activity and more than 9 hours of sleep duration were negatively associated with vitamin D deficiency (all P < 0.05). CONCLUSIONS: It is important that health professions know that the factors proved in this study are connected to vitamin D deficiency thus provide information and intervention strategies of vitamin D deficiency to old aged people.

GENERALIZATION OF THE FROBENIUS THEOREM ON INVOLUTIVITY

  • Han, Chong-Kyu
    • Journal of the Korean Mathematical Society
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    • v.46 no.5
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    • pp.1087-1103
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    • 2009
  • Given a system of s independent 1-forms on a smooth manifold M of dimension m, we study the existence of integral manifolds by means of various generalized versions of the Frobenius theorem. In particular, we present necessary and sufficient conditions for there to exist s'-parameter (s' < s) family of integral manifolds of dimension p := m-s, and a necessary and sufficient condition for there to exist integral manifolds of dimension p', p' $\leq$ p. We also present examples and applications to complex analysis in several variables.

Unrecorded moss species from Korean flora II

  • Yoon, Young Jun;Kim, Chul Hwan;Gorobets, Konstantin-V.;Sun, Byung-Yun
    • Korean Journal of Plant Taxonomy
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    • v.41 no.3
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    • pp.235-241
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    • 2011
  • Five unrecorded species (Oedipodium griffithianum, Myurella tenerrima, Trachypus bicolor, Coscinodon humilis, Meteorium miquelianum subsp. atrovariegatum) with one unrecorded family and two unrecorded genera, were reported as new to the Korean moss flora. The monotypic family Oedipodiaceae consisting of a single genus and single species was distinguished from Splachnaceae by small plants that were 10 mm in length simple or sometimes branched, obovate-spathulate to ${\pm}$ orbicular, costa ending below the apex and entire margins except for the lower long-ciliate portion The species was first found at the top of the Mt. Seorak at an altitude of 1708 m. The two genera, Myurella and Coscinodon were found in the Korean Peninsula. Myurella tenerrima (Theliaceae) was found around the top of Jung-bong on Mt. Jiri. It was mixed with other mosses in the crevices of rocks in the alpine regions. The species is similar to M. sibirica, yet it can be distinguished by the position of papilla in the median laminal cells. Coscinodon humilis (Grimmiaceae) were found on the ridge of Mt. Gaya. C. humilis has a variety of hyaline apex according to leaf position and forms a capsule so it can be distinguished by family. Trachypus bicolor and Meteorium miquelianum subsp. atrovariegatum are unrecorded species. T. bicolor (Trachypodaceae) were found on the ridge of Mt. Gaya. T. bicolor is similar to T. humilis but distinguished by the costal lengths of the leaves. M. miquelianum subsp. atrovariegatum (Meteoriaceae) was found in Gageo-do. This species was distinguished by the plant form and morphology of stem leaves in the same genus.

An analysis of the Influencing Factors and Actual State of Indoor Air Quality in Semi-underground Multi-family Housing Units (다가구주택 반지하세대의 실내공기질 실태 및 영향요인 분석)

  • Choi, Yoon-Jung;Kim, Sun-Young;Kim, Ji-Young;Choe, Sol-Ji
    • Korean Journal of Human Ecology
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    • v.20 no.5
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    • pp.1075-1091
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    • 2011
  • The purposes of this study were to investigate the actual state of indoor air quality in semi-underground multi-family housing units in early summer, to analyze the influencing factors, and to make suggestions for improvement. A series of field investigations were conducted in four target units between June 22, 2010, and June 28, 2010. The field investigations included measurements of indoor air quality as well as the observation of architectural characteristics and living conditions. In addition to the field investigation, on-site questionnaire surveys were administrated to residents in 90 units. The findings are summarized as follows: (1) The average $CO_2$ levels in each of the four units ranged from 759ppm to 1885ppm. $CO_2$ levels in three units exceeded the evaluation standard (1000ppm), and one unit was lower than the standard. This unit had smaller number of staying person and a large amount of ventilation than others; (2) the average CO levels in each unit were almost 0ppm, but 0.1~1.1 levels of CO were revealed at several times; (3) the average PM-10 levels ranged from $8{\mu}g/m^3$ to $40{\mu}g/m^3$, which distributes within the standard ($150{\mu}g/m^3$). The influencing factors of PM-10 levels were analyzed as inflow from outside, the use of a gas range, and the residents' activities; (4) therefore, it was evaluated to be necessary to improve ventilation for the indoor air quality of semi-underground housing in aspect of $CO_2$ levels.

New formula in domination theory and it's application for reliability analysis (Domination이론에서의 새로운 식과 이의 신뢰성계산에 대한 적용)

  • 이광원;이일재;강신재
    • Journal of the Korean Society of Safety
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    • v.11 no.1
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    • pp.16-26
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    • 1996
  • In a series of original papers, [1-17] efficient methods and algorithms have been presented, for the exact solution of many reliability problems represented by binary networks. A starting point of these methods was the concept of domination, firstly introduced in ,elation with reliability problems in [2]. It's application to directed networks resulted in the development of a topological formula for the classical problem of the two terminal reliability. This result was extended later to the all-terminal and the k-terminal reliability problems. All papers mentioned above use a path oriented representation for the network topology. In practical applications, however, it is common and often advantageous to work with cut sets. This article considers the Domination theory for reliability problem of a network. Some topological formula are derived and the power and the application of this formula are shown through the alternative proof of topological formula of A. Satyanarayana [2].

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Expression analysis and characterization of rice oligopeptide transport gene (OsOPT10) that contributes to salt stress tolerance

  • Jung, Yu-Jin;Lee, In-Hye;Han, Kyung-Hee;Son, Cho-Yee;Cho, Yong-Gu;Lee, Myung-Chul;Kang, Kwon-Kyoo
    • Journal of Plant Biotechnology
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    • v.37 no.4
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    • pp.483-493
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    • 2010
  • Knock-out of a gene by insertional mutagenesis is a direct way to address its function through the mutant phenotype. Among ca. 15,000 gene-trapped Ds insertion lines of rice, we identified one line from selected sensitive lines in highly salt stress. We conducted gene tagging by TAIL-PCR, and DNA gel blot analysis from salt sensitive mutant. A gene encoding an oligopeptide transporter (OPT family) homologue was disrupted by the insertion of a Ds transposon into the OsOPT10 gene that was located shot arm of chromosome 8. The OsOPT10 gene (NP_001062118.) has 6 exons and encodes a protein (752 aa) containing the OPT family domain. RT-PCR analysis showed that the expression of OsOPT10 gene was rapidly and strongly induced by stresses such as high-salinity (250 mM), osmotic, drought, $100\;{\mu}M$ ABA. The subcellular localization assay indicated that OsOPT10 was localized specifically in the plasma membrane. Overexpression of OsOPT10 in Arabidopsis thaliana and rice conferred tolerance of transgenic plants to salt stress. Further we found expression levels of some stress related genes were inhibited in OsOPT10 transgenic plants. These results suggested that OsOPT10 might play crucial but differential roles in plant responses to various abiotic stresses.

Mannan-binding lectin of the sea cucumbers Stichopus japonicus has common antigenic determinants with human serum mannan-binding lectin

  • Bulgakov, A.A.;Petrova, I.Yu.;Vakhrusheva, N.M.;Eliseikina, M.G.
    • Proceedings of the Korean Society of Fisheries Technology Conference
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    • 2000.05a
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    • pp.530-530
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    • 2000
  • The host defense system or immune system of all modern animals has their roots in very ancient organisms. After analyzing literature data concerning properties of invertebrates and vertebrates lectins we suggest that mechanism of mannans recognition may exist in marine invertebrates, as a universal mechanism for homeostasis maintenance and host defense, and mannan-binding lectins family of vertebrates has ancient precursor, as was shown for another S-type lectins family. We carried out the screening of mannan-binding type lectin among different species of echinoderms inhabiting in Piter the Grate Bay, the sea of Japan. As a result, the C-type lectins (SJL-32) specific for high mannose glycans was isolated from the coelomic plasma of the sea cucumbers Stichopus japonicus by ion-exchange chromatography on a DEAE-Toyopearl 650M, affinity chromatography on a mannan-Sepharose 6B and gel filtration on a Sephacryl S-200. SJL-32 is homodimer with molecular mass about 32 kDa on SDS-PAGE under non-reducing conditions. Protein part of the lectin has high conteins Asn, Glu, Ser. Hemagglutination of trypsin-treated O blood group human erythrocytes by SJL-32 was competitively inhibited by high-branched -D-mannan composed of -1,2 and -1,6 linked D-mannopyranose residues. In contrast, a variety of mono-, oligo-, and polysaccharides composed of residues of galactose and fucose showed absence or little inhibitory activities. The lectin activity strong depends on Ca2+ concentration, temperature and pH. Monospecific polyclonal antibodies were obtained to the lectin. As was shown by ELISA assay, antibodies to SJL-32 cross-reacted with human serum mannan-binding lectin. This data allows making conclusion about common antigenic determinants and structural homology of both lectins. In our opinion, SJL-32 belongs to evolutionary high conservative mannan-binding lectins (MBLs) family and takes part in the host defense against pathogenic microorganisms.

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The Study of Trnascriptional Regulated Gene, $hrp^{2+}$, in Yeast

  • Choi, In-Soon
    • Journal of Life Science
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    • v.11 no.2
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    • pp.111-115
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    • 2001
  • This study was designed to clone the SNF2/SW12 helicase-related genes from the fission yeast Schizosaccha-romyces pombe and thereafter to elucidate the common functions of the proteins in this family. The $hrp^{2+}$gene was cloned by polymerase chain reaction amplification using degenerative primers from conserved SNF2 motifs within the ERCC6 gene, which encodes a protein involved in DNA excision repair. Like other SNF2/SW12 family proteins, the deduced amino acid sequence of Hrp2 contains DNA-dependent ATPase/7 helicase domains as well as the chromodomain and the DNA binding domain. This configuration is similar to that of mCHD1 (mouse chromo-ATPase/helicase-DNA-dinding protein 1), suggesting that Hrp2 is a S. pombe homolog of mCHD1, which is thought to function in altering the chromatin structure to control the gene expression. To characterize the function of Hrp2, 4 Uracil-Hrp2 fusion protein, it was purified near homogeneity by affinity chromatography on $Ni^{2+}$-NTA agarose, DEAE-Sepharose ion exchange arid Sephacryl S-200 gel filtration chromatographies. The purified fusion protein exhibited DNA-dependent ATPase activity, which was stimulated by both double-stranded and single-stranded DNA. To determine the steady-state level of $hrp^{2+}$ transcripts during growth, cells were cultured in medium and collected at every 2hr to prepare total RNAs. The northern blot analysis showed that the level of $hrp^{2+}$ transcripts reached its maximum before the cells entered the exponential growth phase and then decreased gradually, This result implies that Hrp2 may be required at early stages of cell growth.h.

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Housing Market and Opportunities for Wood Frame Housing in Korea (우리나라의 주택시장구조(住宅市長構造)와 목조주택개발(木造住宅開發))

  • Park, Moon-Jae;Kim, Wae-Jung;Han, Kap-Joon
    • Journal of the Korean Wood Science and Technology
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    • v.19 no.3
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    • pp.45-52
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    • 1991
  • To investigate opportunities for wood frame housing and to activate wood frame house construction, trends of construction activities. preference about housing, and building codes related to wood frame housing were discussed. And two models of wood frame house were developed and construction cost was analyzed to compare with comparative masonry houses. The results obtained were as follows: 1. While 77.8% of people prefer single-family houses, majority of people(74.9%), ironically, possess multi-family houses such as apartments Wood work cost was ratio of 4% of total building cost. while wood material cost accounted merely for 11 % out of total building material cost. 2. Building code was not major barrier to residential house at height under 13m. The building code regulated major structural member and family boder wall of multi-family house to be built with fire retardant material. 3. The proper wood frame house was analyzed of town house or villa type locating in suburban of big city with hot ondol system for the upper middle class. 4 There was no difference in construction cost between western style wood frame house and comparable masonry house, but construction cost for Korean style wood frame house is 27% higher than that of comparable masonry house. It was necessary to reduce materials and cost down by prefabrication technique for both style of wood frame house.

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