• Title/Summary/Keyword: kappa distribution

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Fatty Liver Analysis through Quantitative Measurement Study of Ultrasonography Images (초음파 검사 영상의 정량적인 측정 연구를 통한 지방간 분석)

  • Hye-Ri, Chun;Hyon-Chol, Jang
    • Journal of the Korean Society of Radiology
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    • v.16 no.7
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    • pp.927-934
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    • 2022
  • This study attempted to find out the degree of agreement between ultrasound image findings along with analysis of attenuation index and scatter distribution index values within tissues through quantitative measurement analysis using liver ultrasound images. From August 2022 to October 2022, liver ultrasound was performed on 45 patients who were suspected of having fatty liver and who received a prescription for liver ultrasound. As a result of the study, as a result of analyzing the agreement between the ultrasound image findings and the tissue attenuation index, the Kappa value was 0.82 (p<0.05), showing a very high agreement between the two examination methods. In addition, as a result of the agreement analysis between the ultrasound image findings and the scatter distribution index in the tissue, the Kappa value was 0.642 (p<0.05), showing high agreement between the two examination methods. At the time of fat liver prediction, the use of liver ultrasound findings and quantitative ultrasonography techniques, such as intra-tissue attenuation index and intra-tissue scatter distribution index, may be helpful in determining the degree of progression of fatty liver patients.

Bayesian Estimation of k-Population Weibull Distribution Under Ordered Scale Parameters (순서를 갖는 척도모수들의 사전정보 하에 k-모집단 와이블분포의 베이지안 모수추정)

  • 손영숙;김성욱
    • The Korean Journal of Applied Statistics
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    • v.16 no.2
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    • pp.273-282
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    • 2003
  • The problem of estimating the parameters of k-population Weibull distributions is discussed under the prior of ordered scale parameters. Parameters are estimated by the Gibbs sampling method. Since the conditional posterior distribution of the shape parameter in the Gibbs sampler is not log-concave, the shape parameter is generated by the adaptive rejection sampling. Finally, we applied this estimation methodology to the data discussed in Nelson (1970).

A Sediment Concentration Distribution Based on a Revised Prandtl's Mixing Theory

  • Jung, Kwan-Sue
    • Korean Journal of Hydrosciences
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    • v.8
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    • pp.1-17
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    • 1997
  • Prandtl's mixing length theory was modified to obtain a power velocity distribution in which the coefficient and the exponent are variable over a range from : $$ A simple suspended-sediment concentration distribution was developed from the modified velocity distribytion : $ With nominal values of $\beta$=1.0, $\kappa$=0.4 and visual accumulation tube values of the fall velocity, the comparison between the theory and field measurements by the USGS on the Rio Grande is fair. Doubling the value of the exponent results in a good comparison. Further researches are needed for choosing the values of $\beta$, $\kappa$, and fall velocity values, and consideration on the effects of large-scale turbulence and secondary flows are necessary for them. In a pragmatic sense, on any gaging sites the close analysis of very detailed measurements can establish its specific coefficient and exponent.

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The Study for ENHPP Software Reliability Growth Model Based on Kappa(2) Coverage Function (Kappa(2) 커버리지 함수를 이용한 ENHPP 소프트웨어 신뢰성장모형에 관한 연구)

  • Kim, Hee-Cheul
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.11 no.12
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    • pp.2311-2318
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    • 2007
  • Finite failure NHPP models presented in the literature exhibit either constant, monotonic increasing or monotonic decreasing failure occurrence rates per fault. Accurate predictions of software release times, and estimation of the reliability and availability of a software product require Release times of a critical element of the software testing process : test coverage. This model called Enhanced non-homogeneous Poission process(ENHPP). In this paper, exponential coverage and S-shaped model was reviewed, proposes the Kappa coverage model, which make out efficiency application for software reliability. Algorithm to estimate the parameters used to maximum likelihood estimator and bisection method, model selection based on SSE statistics and Kolmogorov distance, for the sake of efficient model, was employed. Numerical examples using real data set for the sake of proposing Kappa coverage model was employed. This analysis of failure data compared with the Kappaa coverage model and the existing model(using arithmetic and Laplace trend tests, bias tests) is presented.

Lonicera Japonica Inhibits Atopy Dermatitis in NC/Nga Mouse through Regulation of iNOS by NF-${\kappa}B$ Suppression (금은화의 NF-${\kappa}B$ 활성 억제를 통한 iNOS 조절이 NC/Nga 생쥐의 아토피 피부염에 미치는 영향)

  • Ahn, Sang-Hyun;Kim, Ho-Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.2
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    • pp.278-283
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    • 2010
  • Inducible nitric oxide synthase (iNOS) are important inflammation enzyme and severe up-nitric oxide (NO) production by this enzyme has been intricate with pathogenesis of atopy dermatitis. The present study was designed in order to determine whether Lonicera japonica could inhibit atopy dermatitis through modulation of iNOS by NF-${\kappa}B$ suppression. We found that IKK mRNA and iNOS mRNA expression in RAW 264.7 macrophages stimulated with lipopolysaccharide dose-dependantly decreased by Lonicera japonica (0.4 - 1.0 mg/$m{\ell}$) and NO production decreased. The distribution of NF-${\kappa}B$ p65 and iNOS positive reacted cell in NC/Nga mice with atopy dermatitis were decreased by Lonicera japonica (45 mg/kg/day) and apoptosis were increased. These data likely indicate that Lonicera japonica may act as inflammatory regulator for atopy dermatitis through iNOS modulation by NF-${\kappa}B$B suppression and may be possible to develop useful agent for chemoprevention of NO intricate inflammatory diseases.

A Study on the Flow Characteristics in Ejector by PIV and CFD (PIV와 CFD에 의한 Ejector내의 유동특성 연구)

  • Park, Ji-Man;Lee, Haeng-Nam;Park, Kil-Moon;Lee, Duk-Gu;Sul, Jae-Lim
    • Proceedings of the KSME Conference
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    • 2003.11a
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    • pp.723-728
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    • 2003
  • The Ejector is used to get low pressure, and it has been applied to a lot of industry field like the heat engine, the fluid instrument power plant, the food industry, environment industry etc... because there are not any problem even it is mixed with a any kind of liquid, gas, and solid. The flow characteristics in ejector are investigated by PIV and CFD. The experiment using PIV measurement for mixing pipe's flow characteristics acquired velocity distribution, kinetic energy distribution, and whirlpool . (Condition : when mixing pipe's diameter ratio is 1:1.9, and the flux is $Q_{1}=1.136{\imath}/s$, $Q_{2}=1.706{\imath}/s$, $Q_{3}=2.276{\imath}/s$. Based on the PIV and the CFD results, the flow characteristics in ejector are discussed, and it shows the validity of this study.

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NUMERICAL ANALYSIS FOR TURBULENT FLOW AND AERO-ACOUSTIC OVER A THREE DIMENSIONAL CAVITY WITH LARGE ASPECT RATIO (3차원 고세장비 공동 주위의 난류유동 및 음향 특성에 관한 수치적 연구)

  • Mun, P.U.;Kim, J.S.
    • 한국전산유체공학회:학술대회논문집
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    • 2008.03a
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    • pp.297-301
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    • 2008
  • The flight vehicles have cavities such as wheel wells and bomb bays. The flow around a cavity is characterized as unsteady flow because of the formation and dissipation of vortices due to the interaction between the freestream shear layer and cavity internal flow, the generation of shock and expansion waves. Resonance phenomena can damage the structures around the cavity and negatively affect aerodynamic performance and stability. The flow field is observed to oscillate in the "shear layer mode" with low aspect ratio. In the present study, numerical analysis was performed for cavity flows by the unsteady compressible three dimensional Reynolds-Averaged Navier-Stokes (RANS) equations with Wilcox's $\kappa$-$\omega$ turbulence model. The flow field is observed to oscillate in the shear layer mode" with large aspect ratio. Based on the SPL(Sound Pressure Level) analysis of the pressure variation at the cavity trailing edge, the dominant frequency was analyzed and compared with the results of Rossiter's formul. The aero-acoustic wave analyzed with CPD(Correlation of Pressure Distribution).

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NUMERICAL ANALYSIS FOR TURBULENT FLOW AND AERO-ACOUSTIC OVER A THREE DIMENSIONAL CAVITY WITH LARGE ASPECT RATIO (3차원 고세장비 공동 주위의 난류유동 및 음향 특성에 관한 수치적 연구)

  • Mun, P.U.;Kim, J.S.
    • 한국전산유체공학회:학술대회논문집
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    • 2008.10a
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    • pp.297-301
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    • 2008
  • The flight vehicles have cavities such as wheel wells and bomb bays. The flow around a cavity is characterized as unsteady flow because of the formation and dissipation of vortices due to the interaction between the freestream shear layer and cavity internal flow, the generation of shock and expansion waves. Resonance phenomena can damage the structures around the cavity and negatively affect aerodynamic performance and stability. The flow field is observed to oscillate in the "shear layer mode" with low aspect ratio. In the present study, numerical analysis was performed for cavity flows by the unsteady compressible three dimensional Reynolds-Averaged Navier-Stokes (RANS) equations with Wilcox's ${\kappa}-{\varepsilon}$ turbulence model. The flow field is observed to oscillate in the "shear layer mode" with large aspect ratio. Based on the SPL(Sound Pressure Level) analysis of the pressure variation at the cavity trailing edge, the dominant frequency was analyzed and compared with the results of Rossiter's formul. The aero-acoustic wave analyzed with CPD(Correlation of Pressure Distribution).

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Effects of Doche-tang on Colonic Mucosal Ulcer Induced by DSS in Mice (DSS으로 유발된 생쥐의 대장점막손상에 대한 도체탕(導滯湯)의 효과)

  • Lee, Ju-Ah;Kong, Kyung-Hwan
    • The Journal of Internal Korean Medicine
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    • v.29 no.3
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    • pp.752-764
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    • 2008
  • Objectives : This study was carried out to investigate the effects of Doche-tang on colonic mucosal ulcer induced by dextran sulfate sodium(DSS). Method : The group was divided into three. The normal group consisted of mice that were not inflammation-induced. The control group was composed of untreated colitis elicited mice. The sample group was administered Doche-tang after colitis elicitation. The effects on colonic mucosal ulcers were evaluated by the morphological change of colonic mucosa, the anti-oxidant effect, HSP 70, $NF-{\kappa}B$, COX-1, COX-2 and iNOS. Results : In terms of immunohistochemical findings, the distribution of COX-1 in mice treated with Doche-tang noticeably increased more than that in the control group. The distribution of HSP70, $NF-{\kappa}B$, COX-2, iNOS in mioe treated with Doche-tang decreased more than that in the control group. Regeneration of surface epithelial cell and goblet cell in mucosa was observed by transmission electron microscope. Conclusion : According to the results, Doche-tang is practicable treatment for colonic mucosal ulcer.

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The Effect of Chungpyesagantang on Lipopolysaccharide induced Arthritis in Mice (청폐사간탕(淸肺瀉肝湯)이 생쥐의 Lipopolysaccharide 유발 관절염(關節炎)에 미치는 영향(影響))

  • Park, Seong-Sik;Kim, Ju-Hee
    • Journal of Sasang Constitution and Immune Medicine
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    • v.14 no.3
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    • pp.114-131
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    • 2002
  • 1. PURPOSE : The purpose of this study is to investigate the effect of Chungpyesagantang on LPS induced Arthritis in Mice. 2. METHOD : All the BALB/C Mice used in this study were 4wks of age at the start of the experiment. The experimental model of Arthritis was induced by injectection of $300{\mu}g/kg$ LPS in mice knee joint. The experiment was compare daily CS treatment group after Arthritis elicitation with Arthritis elicitated group at day 4, 7, 14 after Arthritis elicitation. 3. RESULTS 1) The hyperplasia of synoviocytes of CS treatment group after Arthritis elicitation is soften than Arthritis elicitated group. 2) The aggregation of collagen fibers CS treatment group after Arthritis elicitation is decreased than Arthritis elicitated group. 3) The distribution of TUNEL positive cells(apoptotic cell) of CS treatment group was remarkably increased than Arthritis elicitated group. 4) The distribution of $TNF-{\alpha}$, $NF-{\kappa}B\;p50$, COX-2 positive cells of CS treatment group after Arthritis elicitation in synovial membrane was decreased than Arthritis elicitated group. 5) The distribution of $IL-2R-{\alpha}$, ICAM-1 positive cells of CS treatment group after Arthritis elicitation in apical surface of synovial membrane was decreased than Arthritis elicitated group. 6) The distribution of $NF-{\kappa}B\;p50$, $IL-2R-{\alpha}$ in common iliac lymph node of CS treatment group after Arthritis elicitation positive cells was decreased than Arthritis elicitated group. 4. CONCLUSION : As a result of these experimental results, it may be concluded that Chungpyesagantang used for treatment of LPS induced Arthritis in Mice. Inflamation activity in CS treatment group after Arthritis elicitation was decreased than Arthritis elicitated group.

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