• 한국해안·해양공학회논문집
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• 제24권4호
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• pp.235-246
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• 2012

연안방재계획 수립을 위한 기초자료 생성의 일환으로 태풍에 의한 해일 범람모의를 수행하였다. 통상적인 침수-노출 처리가 불가한 직립안벽을 갖는 항만역의 특징이 반영되도록 가상의 내부제방 개념을 도입하여 해석하였다. 목포항에 대한 실제해역 적용에 앞서 단순해역에서 다수의 적용성 평가를 통해 내부제방의 폭은 1 m가 적정한 것으로 평가되었다. 해일범람으로 인한 침수면적과 침수심 산정에 민감하게 작용하는 육역의 침수-노출 처리기법에서의 최소침수심은 격자에 의존적이나 10 m 내외의 유한요소 상세격자에서는 0.01 m가 적정한 것으로 판단된다. 기존 태풍경로에 준거한 100년 빈도급 중심기압과 최대풍속을 가지며 비대칭 경도풍과 파랑효과가 고려된 가상태풍의 내습에 따른 목포해역의 침수예상역이 모의되었다. 침수면적은 기존 연구결과와 유사성을 나타내지만 항만권역 일부에서 확대 가능성이 있는 것으로 평가된다.

• 한국유체기계학회 논문집
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• 제18권3호
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• pp.38-45
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• 2015

In this study, two computational methodologies were compared to consider an effective conjugate heat transfer analysis technique for the cooled vane with thermal barrier coating. The first one is the physical modeling method of the TBC layer on the vane surface, which means solid volume of the TBC on the vane surface. The second one is the numerical modeling method of the TBC layer by putting the heat resistance interface condition on the surface between the fluid and solid domains, which means no physical layer on the vane surface. For those two methodologies, conjugate heat transfer analyses were conducted for the cooled vane with TBC layer having various thickness from 0.1 mm to 0.3 mm. Static pressure distributions for two cases show quite similar patterns in the overall region while the physical modeling shows quite a little difference around the throat area. Thermal analyses indicated that the metal temperature distributions are quite similar for both methods. The results show that the numerical modeling method can reduce the computational resources significantly and is quite suitable method to evaluate the overall performance of TBC even though it does not reflect the exact geometry and flow field characteristics on the vane surface.

• Composites Research
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• 제33권3호
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• pp.147-152
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• 2020

본 연구에서는 스파/스킨 복합재 일체형 구조물 시편 제작을 통해 구조물 형상에 의한 국부적인 내부압력 구배 및 표면접착필름 적용 조건에 따른 복합재 내부 기공의 거동에 대하여 실험적으로 평가하였다. 표면접착 필름과 탄소섬유 프리프레그 소재의 점도특성 및 열분석 비교를 통해 경화특성 및 속도 차이를 확인하였다. 그리고 스파/스킨 일체형 구조물 시편을 표면접착필름 적용 조건에 따라 2가지 유형으로 성형 제작하여 표면상태검사, 비파괴 검사 및 파괴 검사를 통하여 검증하였다. 표면접착필름이 전체 표면에 적용된 시편#1의 경우 내부구조에 의한 압력 구배가 발생하고 이로 인해 낮은 압력이 적용되는 부위에서 형성된 기공들이 먼저 경화된 표면접착필름에 막혀 배출되지 못함을 확인할 수 있었으며, 표면접착필름이 적용되지 않아 탄소섬유 프리프레그가 전면 노출된 시편#2에서는 내부 기공이 완전히 배출됨을 볼 수 있었으며 미리 경화된 표면접착필름이 내부 기공 이동 및 배출에 있어서 차단막(Barrier film)으로 작용할 수 있음을 확인하였다.

• 토지주택연구
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• 제7권4호
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• pp.225-237
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• 2016

본 연구는 지난 2007년 도입된 장애물 없는 생활환경(Barrier Free) 인증제도의 확산과 정착을 위하여 불특정 다수가 이용하는 다중이용시설로써 인증제도의 확산효과가 클 것으로 예상되는 여객자동차 터미널을 대상으로 편의시설 실태를 파악하고, 인증가능성을 평가하여 인증 확산 방안을 마련하고자 하였다. 전국 여객자동차 터미널 349개소에 대하여 편의시설 설치 수준 현황조사를 시행하였다. 현황조사 결과 인증가능시설이 217개소, 인증불가시설이 58개소로 평가되었고, 인증가능성이 높은 29개 시설은 소규모 리모델링 공사를 통하여 인증을 획득할 수 있는 시설로 평가되었다. 실태조사 결과, 여객자동차 터미널의 BF수준은 40~55% 수준이며, 평가분야별로는 내부시설이 90% 이상으로 수준높은 반면, 매개시설, 위생시설, 안내시설 등은 절반 수준에도 미치지 못하고 있다. 본 연구에서는 여객자동차 터미널의 편의시설 수준제고를 위해서 BF 인증 시범사업을 제안하였다. 인증가능성이 높고, 지자체 지원의지와 사업주의 편의시설 개선의지가 높은 시설을 대상으로 시범사업대상으로 선정하고 편의시설개선을 추진하여 BF인증을 추진하고 모니터링하는 방안이다.

• 한국임상수의학회지
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• 제38권4호
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• pp.194-198
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• 2021

A 7-year-old intact male Maltese dog was presented with firm, raised, erythematous, alopecic, and pruritic skin lesions on the right dorsal distal metatarsal region and the tail. The skin lesion started a year ago with a crust-like lesion on the right dorsal distal metatarsal region which gradually swelled as the patient continued to lick and chew without healing. Recently, similar lesions occurred on the tail. Based on the licking history and ruling out other diseases through skin examination, acral lick dermatitis (ALD) was diagnosed. Treatment included antidepressants, preventive antibiotics, topical corticosteroid, and wearing Elizabethan collar as a physical barrier. After three weeks, the lesion on the hind limb healed entirely. However, the tail lesion recurred as it was able to lick the tail again with a type of an E-collar. This case shows that it is essential to block the contact lesion and provide medical treatment until the lesion has been completely resolved for successful management of ALD.

• 농촌지도와개발
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• 제23권1호
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• pp.39-51
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• 2016

The purpose of this study is to examine the female marriage immigrants' social unification through their employment. The subjects of this study were 116 female marriage immigrants who lived in Kyungi-do. This study analyzed employment desire, barrier and volition differences of female marriage immigrants between their socio-demographic factors and effects of their employment desire and barrier to employment volition. Results of this study; First, desire of maintenance of livehood and self esteem to employment incresed with age. Second, there were differences in desire of maintenance of livehood and self esteem to employment between their countries of origins. Third, employment volition and self esteem to employment increased with level of education. Fourth, there were differences in employment volition and self esteem to employment between the length of residence in Korea. Fifth, employment desire and self esteem to employment increased with ability to Korean, but internal barrier of employment decreased by ability to Korean. Sixth, desire of identity from employment and self esteem to employment increased with the number of children. Seventh, employment desire influenced employment volition, self efficacy and self esteem to employment.

• Journal of Korean Neurosurgical Society
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• 제50권1호
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• pp.45-47
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• 2011

Abnormal contrast enhancement on brain computed tomography (CT) scan after diagnostic or interventional angiography is not rare, and has known to be induced by temporary blood-brain barrier (BBB) disruption from contrast media. Furthermore, it has been regarded as clinically subtle, but reported to have no symptom or mild transient symptoms. However, we recently experienced two cases of serious BBB disruption during the acute period after coiling of an unruptured intracranial aneurysm. One patient presented with an unruptured paraclinoid internal carotid artery (ICA) aneurysm on the right and the other with an unruptured right supraclinoid ICA aneurysm. Both patients showed similar findings on immediate postembolization CT scan and clinical courses after coiling. Typical radiological, clinical characteristics of BBB disruption were described. In addition, the role of immediate postembolization CT scan are also discussed.

• Corrosion Science and Technology
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• 제2권3호
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• pp.155-160
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• 2003

Plasma spraying technique was used to fabricate functionally graded coating (FGC) of NiCrAIY/YSZ 8wt%$Y_2O_3-ZrO_2$ on a Co-base superalloy (HAYNES 188) substrate. Six layers were coated on the substrate for building up compositionally graded architecture. Conventional thermal barrier coating (TBC) of NiCrAIY/SZ with sharp interface was also fabricated. As-coated FGC and TBC samples were exposed at the temperature of $1100^{\circ}C$ for 10, 50, 100 hours in air. Microstructural change of thermally exposed samples was examined. Pores and microcracks were formed in YSZ layer due to evolution of thermal internal stress at high temperature. The amount of pores and microcracks in YSZ layer were increased with increasing exposure time at high temperature. High temperature oxidation of coatings occurred mainly at the NiCrAIY/YSZ interface. In comparison with the case of TBC. the increased area of the NiCrAIY/YSZ interface in FGC is likely to attribute to forming the higher amount of oxides.

• 약학회지
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• 제46권2호
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• pp.124-128
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• 2002

The nitrone-based free radical trapping reagent, $\alpha$-phenyl-n-tert-butyl nitrone (PBN) has been proposed as therapeutic agent for stroke. We used this for model drug of development of new drug for neuroprotection. The purpose of this study was to evaluate the blood-brain barrier (BBB) permeability of PBN in Sprague-Dawly (SD) rats. The BBB transport of PBN was investigated in SD rats using internal carotid artery perfusion (ICAP) method at a rate of 4 mι/min for 15 second. We also obtained pharmacokinetic parameters of PBN using single intravenous injection technique. When we estimated BBB permeability of PBN with ICAP method, the brain volume of distribution of PBN was 60.0 $\pm$ 12.0 $\mu\textrm{g}$/ι. The brain uptake of PBN after IV injection at 120 min was 0.15 $\pm$ 0.01%ID/g. The PBN was transported to the brain through the BBB well in rats, because PBN is small molecule (MW 177) and lipid-soluble (log P 1.23) compound.

• 약학회지
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• 제51권1호
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• pp.1-6
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• 2007

The aim of this study was to examine whether administration of glutamine are able to prevent the methotrexate induced gut barrier damage, bacterial translocation, and weight changes. The animals with glutamine were fed with L-glutamine (1.2 and 2.4 mg/kg/day) for 7 days before methotrexate administration (20 mg/kg orally). 48 hour after methotrexate administration, intestinal permeability were measured for an assessment of the gut barrier dysfunction. Also, enteric aerobic bacterial counts, number of gram-negatives in mesenteric lymph node (MLN), liver spleen, kidney and heart were measured for an assessment of the enteric bacterial number and bacterial translocation. Amounts of food intake, body weight changes and organ weight changes of liver spleen, kidney and heart were measured. Methotrexate administration caused body and liver weight loss regardless amounts of food intakes. Methotrexate induced increasing intestinal permeability, enteric bacterial undergrowth and bacterial translocation to MLN, liver and spleen, but not kidney and heart. The supplements with glutamine reduced the intestinal permeability bacterial translocation, and not influences enteric bacterial number, and body and liver weight changes. This study suggested that glutamine might effectively reduce methotrexate induced intestinal damage and bacterial translocation, but not influence body and organ weight loss.