• Korean Journal of Social Welfare Studies
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• v.49 no.1
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• pp.297-334
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• 2018

This study focused on accomplishment of successful life development after discharge a child-care facility even though they had a variety of diversity in hard environment on their own past. Furthermore the research analyzed expression progress and detail information of resilience effect on twenty healthy members of society, who lived theirselves for more than 10 years at out of chid-care centers, based on grounded theory methodology participants. As written in the result section of the study, using the paradigm model analysis showed that it was caused by 'Practical planning for the future', 'Organization of positive meaning' and 'Understanding in another's shoe'. The contextual condition appeared as 'Self examination, 'Seeking anchor as ontology' and 'Natural intimacy among family members'. The centralization phenomenon came in 'Living philosophy of internal stabilities'. The intervention condition appeared as 'Rise up through the world' and 'faith all the world'. The action-interaction showed up as 'Strict self-discipline' and 'Growing up own family'. The consequence appeared as 'Making social family' and 'Being a someone's social mentor'. This research shows discussion in depth based on above analyzed result.

• Economic and Environmental Geology
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• v.52 no.5
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• pp.471-484
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• 2019

Liquefaction occurs by a temporal loss of sediment strength as a consequence of increased pore water pressure during the re-arrangement of unconsolidated, granular sediments. Liquefaction is dependent on the physical properties of the sediments and cause surface cracks, landslide, and the formation of soft-sediment deformation structures(SSDS). SSDS is formed by the combined action of the driving force and deformation mechanism(liquefaction, thixotropy, and fluidization) that is triggered by endogenic or exogenic triggers. So research on the SSDS can unravel syndepositional geological events. If detailed sedimentologic analysis together with surrounding geological context suggest SSDS formed by earthquakes, the SSDS provide a clue to unravel syndepositional tectonic activities and detailed paleoseismological information(> Mw 5) including earthquakes that leave no surface expression.

• Journal of Convergence for Information Technology
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• v.11 no.10
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• pp.1-9
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• 2021

Although interest in the metaverse increases due to the pandemic, the understanding of the metaverse interest factor, which is an essential element for the sustainability of any metaverse platform, is lacking. This study aims to reveal the interest factors of metaverse services by analyzing user community discourse. We collected user community discourses from and applied LDA to extract topics. Further, we categorize the factors into growth and verifiable indicators, various levels of interaction, self-expression and freedom, and connection with the real world. The content planning direction of the game-based metaverse of utilization was derived. This study is meaningful in that it analyzes the interest factors of the metaverse based on the empirical evidence of user discourse data.

• Journal of Convergence for Information Technology
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• v.11 no.5
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• pp.190-198
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• 2021

The aim of the study was to evaluate the physiological activity of Lycium ruthenicum to investigate their potential as a raw material that can be used in the cosmetic industry. L. ruthenicum fruit extracts were obtained using 70% methanol(LRM) and hot-water(LRW). The DPPH and ABTS radical scavenging abilities were higher in the LRM extract than in the LRW extract. The FRAP value of LRM was about 1.3-fold greater than that of LRW. The polyphenol contents of LRM and LRW were 31.883±1.395 mg/g and 27.748±2.741 mg/g respectively. LRM inhibited the generation of NO in LPS-stimulated RAW264.7 cells. LRM also attenuated the expression of COX-2, PGE2, IL-6, and TNF-α induced by LPS. These results suggests that L. ruthenicum fruits could be use as a source of natural antioxidants and anti-inflammatory agent in cosmetic products.

• The Journal of Korean Medical History
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• v.34 no.2
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• pp.89-96
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• 2021

This research aims to find a way to utilize the literature to select the herbs to be added or subtracted according to the condition of the patient after determining the basic prescription to be used for the patient. The study is based on data concerning the herbal composition and application of prescriptions described in the Donguibogam. The composition herbs was expressed as a weight ratio, the standard deviation of the weight ratio was calculated for each prescription, and the case where the weight ratio was greater than the base value (highest weight ratio - standard deviation) was designated as a principal herb. The various expressions of applications were changed to representative terms by the researcher and used to calculate the frequency. Of the 4,373 prescriptions for Donguibogam, 3,307 were able to be expressed in terms of weight ratios with 640 prescriptions using Rehmannia glutinosa, Cnidium officinale, Angelica gigas and Paeonia lactiflora as the principle herb. Of the 640 prescriptions, 508 prescriptions included applied information. Rehmannia glutinosa can also be used for symptoms such as fetal leakage(胎漏), short ingestion(食少), fever(發熱), dazed expression(眼花). Cnidium officinale can also be used for symptoms such as migraine(偏頭痛), stroke(中風癱瘓), tetanus(破傷風). Angelica gigas can also be used for symptoms such as forgetfulness(健忘), incontinence of urination(小便不通), palpitations(驚悸). Paeonia lactiflora can also be used for symptoms such as heart pain and abdominal pain(心腹痛), cough(咳嗽).

• Journal of Convergence for Information Technology
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• v.9 no.7
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• pp.135-144
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• 2019

This study was conducted in order to be applied to basic data for enhancing dental hygienists' retention intention. Data analysis was carried out a univariate analysis and a hierarchical regression analysis over 3 stages by using SPSS version 19.0. The dental hygienists' retention intention showed a high outcome in case of the married(p<.001), in the more positive emotion(p<.001), in the lower frequency of emotional expression(p=.010), in the higher happiness index with life satisfaction(p<.001) and in the higher psychological happiness index(p=.012). The dental hygienists' emotion, emotional labor and happiness index need to be recognized as important relevant factors for increasing retention intention.

• Genes and Genomics
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• v.40 no.12
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• pp.1363-1371
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• 2018

One of the main concerns in biology is extracting sophisticated features from DNA sequence for gene interaction determination, receiving a great deal of researchers' attention. The epigenetic modifications along with their patterns have been intensely recognized as dominant features affecting on gene expression. However, studying sequenced-based features highly correlated to this key element has remained limited. The main objective in this research was to propose a new feature highly correlated to epigenetic modifications capable of classification of genes. In this paper, classification of 34 genes in PPAR signaling pathway associated with muscle fat tissue in human was performed. Using different statistical outlier detection methods, we proposed that 5-mers highly correlated to epigenetic modifications can correctly categorize the genes involved in the same biological pathway or process. Thirty-four genes in PPAR signaling pathway were classified via applying a proposed feature, 5-mers strongly associated to 17 different epigenetic modifications. For this, diverse statistical outlier detection methods were applied to specify the group of thoroughly correlated genes. The results indicated that these 5-mers can appropriately identify correlated genes. In addition, our results corresponded to GeneMania interaction information, leading to support the suggested method. The appealing findings imply that not only epigenetic modifications but also their highly correlated 5-mers can be applied for reconstructing gene regulatory networks as supplementary data as well as other applications like physical interaction, genes prioritization, indicating some sort of data fusion in this analysis.

• Journal of IKEEE
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• v.23 no.3
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• pp.934-940
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• 2019

In this paper, we propose a Reverse Differential Chaos Shift Keying (RE-DCSK) system for low cost, high reliability and high data rate non-coherent chaos communication .In RE-DCSK, reference signals are transmitted in the first slot as in the conventional differential chaos shift modulation scheme (DCSK) and in the second slot a time inversion block strengthens the autocorrelation of the chaos signal and uses the orthogonality of the two signals to obtain the information signal. RE-DCSK enables relatively double the data rate compared to DCSK and also improves the security of communications without any additional cost of system complexity.To prove its effectiveness, we analyze it through Rayleigh fading channel and additional white Gaussian noise (AWGN) channel based on the derived BER expression. The BER performance of the proposed system is improved when compared with the CDSK and DCSK system using AWGN channel.

• Journal of Convergence for Information Technology
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• v.9 no.6
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• pp.227-232
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• 2019

This study suggests a new direction for designing art masks that receive attention as an area of creative expression for makeup by incorporating Neo-Pop art. After analyzing the characteristics of Neo-Pop from a theoretical perspective, the researcher produced four art masks based on each characteristic by utilizing the motif of the Japanese Pop artist Takashi Murakami. From this study, the researcher elicits that Neo-Pop has enough qualities to be utilized as a material for the art mask, new designs of the art mask may be suggested by applying the characteristics of Neo-Pop, and that the convergence of art and makeup highlights the possibility of convergence among the many other fields. Thus, it is expected that the art mask will be studied further through converging with a range of fields, and this study will be used as fundamental data for the development of the art mask design.

• Biomolecules & Therapeutics
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• v.27 no.2
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• pp.201-209
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• 2019

Mixed lineage leukemia proteins (MLL) are the key histone lysine methyltransferases that regulate expression of diverse genes. Aberrant activation of MLL promotes leukemia as well as solid tumors in humans, highlighting the urgent need for the development of an MLL inhibitor. We screened and isolated MLL1-binding ssRNAs using SELEX (${\underline{S}}ystemic$ ${\underline{E}}volution$ of ${\underline{L}}igands$ by ${\underline{E}}xponential$ enrichment) technology. When sequences in sub-libraries were obtained using next-generation sequencing (NGS), the most enriched aptamers-APT1 and APT2-represented about 30% and 26% of sub-library populations, respectively. Motif analysis of the top 50 sequences provided a highly conserved sequence: 5'-A[A/C][C/G][G/U][U/A]ACAGAGGG[U/A]GG[A/C] GAGUGGGU-3'. APT1, APT2, and APT5 embracing this motif generated secondary structures with similar topological characteristics. We found that APT1 and APT2 have a good binding activity and the analysis using mutated aptamer variants showed that the site information in the central region was critical for binding. In vitro enzyme activity assay showed that APT1 and APT2 had MLL1 inhibitory activity. Three-dimensional structure prediction of APT1-MLL1 complex indicates multiple weak interactions formed between MLL1 SET domain and APT1. Our study confirmed that NGS-assisted SELEX is an efficient tool for aptamer screening and that aptamers could be useful in diagnosis and treatment of MLL1-mediated diseases.