• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.5
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• pp.1120-1128
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• 2005

To investigate the toxic of herbs used in , the author analyzed herbs with toxic recorded in , , after searched toxic herbs literarily. Herbs with toxicity recorded in both and were total 17 species, and recorded in were total 13 species, and recorded in were total 12 species. The major cause that herbs generates a side effect in a human body is implicit use and abuse, inadequate processing the herbs, use of quack medicines of herbs and clinical use which is improper in symptoms and internal use, differences of constitution. The major toxic component in herbs is an alkaloid, essential oil and hydrargyrum (Hg), and the main invasion route of toxic herbs in human body is the liver, kidney, lungs, and gastrointestinal tract.

• Journal of Society of Preventive Korean Medicine
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• v.11 no.2
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• pp.87-99
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• 2007

Background : Most traditional Korean doctors use "Packed Herbal Medicine", which is made from boiling various herbs together. However, the current insurance system doesn't cover the act of making packed herbal medicine. Therefore it is urgent for these doctors to study and find the best and most logical insurance program to cover the Packed Herbal Medicine system. Objectives : The purposes of this study were to investigate whether Announced System of Herb Price is proper for stability of medical herbs's price. Methods : This study made these following results by studying medical herbs's price of KOMD(The korea oriental medicine distribution company) from 2004 March to 2007 March The results are summarized as follows ; The 50 most frequently used herbs were chosen from the 831 standard prescriptions according to 26 pre-determined specific diseases. These prescriptions are considered the most important for this study and insurance purposes. fluctuations of fifty medical herbs which were used much about a predetermined list of 831 prescriptions are multiple function not linear equation. fluctuations of fifty medical herbs which were used much about a predetermined list of 831 prescriptions are different according to time. Therefore, to notify medical herbs's price is valid method for stability of medical herbs's price.

• Herbal Formula Science
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• v.17 no.2
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• pp.1-20
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• 2009

The purpose of this study was to examine how exterior-relieving herbs are blended by each prescription with emphasis on Internal disease range of Donguibogam by limiting Wind herbs in exterior-relieving herbs to apply exterior-relieving herbs to internal diseases. Prescriptions mixed with exterior-relieving herbs is a prescription adding Bojungikgitang, Yijintang, Yimyosan, Yukilsan and Gilgyeongjigaktang. The mixed exterior-relieving herbs were diversely operated according to each prescription or medicines. However, the mixed exterior relieving herbs were mixed for rising yang & tonifying qi(升陽益氣) for the most part. The exterior-relieving herbs mixed with prescriptions had the total 15 kinds, Bupleuri Radix, Cimicifugae Rhizoma among them were mixed with prescriptions for the most part. In addition, two-kind mixed exterior-relieving herbs were utilized in order of Bupleuri Radix Cimicifuga Rhizoma and Bupleuri Radix Cimicifugae Rhizoma Notopterygii Rhizoma Ledebouriellae Radix. Taken together, Wind herbs is applied several purpose, so that it can contribute to treatment and prevention of internal diseases in present-day.

• The Journal of Korean Medicine
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• v.40 no.4
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• pp.29-40
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• 2019

Objectives: To analyze the prescription frequency of various herbs as either individual or major herbs (in terms of dosage) and their usage patterns in the treatment of different diseases for standardization of traditional Korean medicine. Methods: We analyzed the prescription database of patients at the Pusan National University Korean Medicine Hospital from the date of establishment of the hospital to February 2013. The complete prescription data were extracted from the electronic medical records of patients, and the prescription frequencies of individual herbs, particularly, of major herbs, were analyzed in terms of gender, age, and international classification of diseases (ICD) code. Results: The prescription frequency of individual herbs based on age and gender showed a similar pattern. Herbal mixtures were also distributed in a similar manner. The use of some herbs differed according to age and gender (Table 1.). The herbs that were used at high frequencies for a given ICD code had similar usage patterns in different categories. However, some major herbs in the "Jun (King)" category were used uniquely for a given ICD code (Table 2.). There was significant difference between male and female on ICD code E and N, but the other ICD codes had small differences. The ratio of herbal medicine by gender showed different usage patterns in each gender. Conclusions: The findings of our study provide fundamental data that reflect the real clinical conditions in South Korea, and therefore, can contribute to the standardization of TKM.

• Journal of Society of Preventive Korean Medicine
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• v.18 no.2
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• pp.81-88
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• 2014

Objective : This study is a survey research that investigates the kinds of medicinal herbs actually used in Yaksun(medicianal food) restaurants, the frequency and the way of using herbs in Yaksun. Through this study, we assumed that it will be used basis data on further Korean Yaksun research. Method : We conducted survey targeting for 26 Yaksun restaurants and Temple food restaurants serving Yaksun cuisine(medicinal food) menu from July 2012 to January 2013. The questionnaire was composed of several parts including the kinds of medicinal herbs that was used in Yaksun, medicinal food types that use a lot of medicinal herbs, medicinal herbs criteria used in the selection of medicinal food, and education experience learning Yaksun cuisine. Results : Only 11 restaurants answered the questionnaire among the targeting restaurants of survey objects. The number of Herbs was investigated in each restaurant was maximum 65 kinds and minimum 7 kinds (average 32 kinds). All restaurants used Angelicae Gigantis Radix in their restaurant. And Nelumbinis Semen, Zingiberis Rhizoma, Glycyrrhizae Radix, Acanthopanacis Cortex, and Gardeniae Fructus are well used medicinal herbs in Yaksun. Types of medicinal food using a lot of herbs were rices porridges rice cakes, both vegetables salads and stews soups. Almost chefs or restaurant's representatives learned cooking medicinal food at temples, food research centers, university attached institutions, and cooking schools. Conclusion : Medicinal herbs used in Yaksun restaurants are familiar with Korean and easily available. These herbs has better efficacy, taste, scent, color in comparison of the others. For the development of Korean Yaksun, further research of divers parts in Yaksun materials should be conducted.

• Journal of Sasang Constitutional Medicine
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• v.23 no.1
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• pp.79-86
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• 2011

1. Objectives: Pharmacopuncture according to Sasang Constitutional Medicine is new field of constitutional medicine. We investigated safety of pharmacopunctures to develop this treatment. 2. Methods: We searched for papers in fifteen Korean oriental medical journals and four online searching portal articles. Hepatotoxicity, nephrotoxicity and general toxicity tests were investigated about one hundred thirty kinds of pharmacopunctures. 3. Results: Toxicity test about 36 kinds of 130 pharmacopunctures were investigated. 1) Hepatotoxicity and nephrotoxicity test of pharmacopunctures were searched in 11 of 38 Soeumin herbs, 8 of 36 Soyangin herbs, 5 of 44 Taeeumin herbs and 1 of 12 Taeyangin herbs. From among these herbs, toxicity was detected in Radix aconiti lateralis preparata(附子), Fructus alpiniae oxyphyllae(益智仁), Semen crotonis(巴豆), Radix bupleuri(柴胡) and Semen armeniacae amarum(杏仁) pharmacopunctures. 2) General toxicity test of pharmacopunctures were searched in 8 of 38 Soeumin herbs, 9 of 36 Soyangin herbs, 6 of 44 Taeeumin herbs and 2 of 12 Taeyangin herbs. from among thes herbs, toxicity was detected in Radix aconiti lateralis preparata(附子), Radix ginseng(人蔘), Semen crotonis(巴豆), Rhizoma seu radix notopterygii(羌活), Radix aralia cordatae(獨活), Semen armeniacae amarum(杏仁) and Radix scutellariae(黃芩) and Cortex acanthopanacis(五加皮) pharmacopunctures. 4. Conclusions: From these results, we must decide extraction method, concentration and dose carefully to use the toxic pharmacopuncture. More toxicity test and further study is needed about pharmacopuncture treatment in Sasang Constitutional Medicine.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.15 no.1
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• pp.162-175
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• 2002

Aromatherapy is used in many diseases nowdays. And, Aromatherapy is similar to historical oriental medicine. Moreover, Aroma is a popular alternative medicine like oriental medicine in these days. We used for all kinds of diseases with aroma herbs, especially in ENT and dermatological disese. We must be a bridge over oriental and western medicine with aromatherapy, because it will help reduce stress in pschosomatic disorder. We have to accept aromatherapy as oriental medicine paradigm for better holistic medicine. Method :We analyzed 20 herbs difference and similarity both aroma herb and oriental herb. We reseach for a scientific name, family, therapeutic region, efficacy, perfumery note, nature. The results were as follows: 1. Most of herbs are similar to each other in the treatment. Top, middle, bottom is similar to sam-cho(三焦) sang-cho, zhong-cho, ha-cho, and But futher reseach is needed for development of Oriental medicine. 2. We find out much similarity between oriental herbs and aromatic herbs and qi-mi ron(氣味論) is useful to analyze them 3. We find out difference mechanism between GI absortion and nasal inhalation. 4. Other Aroma herbs must be analyzed by oriental oriental medical thought, for example, seung-gang-bu-chim(昇降浮沈), gui-gyong(歸經), and so on. 5. Aromatic oriental medicine ways are developed like aromatic therapy.

• Journal of Sasang Constitutional Medicine
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• v.31 no.3
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• pp.19-33
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• 2019

Objectives The network pharmacological study on herbal remedies in Traditional Chinese Medicine (TCM) is actively being carried out based on the TCM databases such as TCMID and TCMSP. It is necessary to select Sasang Constitution-specific (SC-s) herbs from these databases in order to study the prescriptions in Sasang Constitutional Medicine. Methods SC-s herbs and their processing types listed in "Dongyisusebowon Sinchukbon" were searched from TCMID and TCMSP. Results and Conclusions 1. There were total 144 herbs (Soeum 47, Soyang 37, Taeeum 44, Taeyang 16 specific herbs) listed in "Dongyisusebowon Sinchukbon". 2. There were total 130 herbs (Soeum 43, Soyang 37, Taeeum 42, Taeyang 8 specific herbs) searched from TCMID, and total 92 herbs (Soeum 31, Soyang 30, Taeeum 27, Taeyang 4 specific herbs) from TCMID. 3. In some cases, the name given in "Dongyisusebowon Sinchukbon" was different from that in TCMID and TCMSP. It was needed to be careful during the searching process. 4. Although the processing form of some herbs could be searched, there was a significant reduction in the herbal compound information compared to the raw form. It is necessary to reconsider whether or not to use the processing form. 5. Herbal scientific names given in TCMID and TCMSP or used in China and Korea were different each other in some cases. Additional screening process among such herbs would be required based on the efficacy of herbs used in clinical field.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.6
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• pp.443-450
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• 2015

The purpose of this study was is to understand how the network pharmacology databases of traditional medicine in China are established and provide suggestion for successful implementation in Traditional Korean Medicine. We searched for network-pharmacology-related TCM Databases provided on the internet, and analysed their contents. Then, we compared herbs related to Sasang with herbs of the TCM Databases. We chose 8 network-pharmacology-related TCM Databases. They shared information about compounds, herbs, formulae, drugs, targets and diseases, and provided interaction networks between these components. In comparison with herbs related to Sasang, TCMSP Database did not have information about 99 herbs in total, and 25 herbs included in major Sasang formulae. The implications and recommendations for Traditional Korean Medicine researches were discussed. Based on the results of this primary study, more related studies should be carried out in the future.

• CELLMED
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• v.5 no.2
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• pp.11.1-11.5
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• 2015

Traditional East Asian Medicine (TEAM) prescriptions typically consist of several herbs based on the assumption that the herbs operate synergistically and/or cooperate on several related pathways simultaneously. This is a general concept that is widely accepted in TEAM, but it has not been tested systematically. To check this assumption statistically, we have text mined traditional Korean medicine text the Inje-ji(仁濟志, Collections of benevolent savings), a text that contains more than 5000 herb-cocktail prescriptions. We created herb-pairing network based on herb-herb pairing specificity and performed a systematic network analysis. Herbs were shown to be used selectively with other herbs and not randomly. Moreover, herb pairs were more specifically associated with symptoms than were single herbs. Single herbs and combinations of herbs specifically used for diabetes mellitus were successfully identified. As conclusion, herb-pairings in TEAM are not randomly constructed; instead, each herb was selectively used with other herbs. In terms of statistical significance, herb pairs were more specifically associated with symptoms than were single herbs alone. Collectively, these results suggest that it may be important to understand the interactions among multiple ingredients contained in herb pairs rather than trying to identify a single compound to resolve symptoms.