• 대한한의학회지
• /
• 제17권2호
• /
• pp.251-263
• /
• 1996

In order to investigate experimentally that effect of Moschus, Bovis Calculus, Ursi Fel aqua-axupuncture on acutely damaged liver of rats induced by radix aconiti. The author admininisterated aqua-acupuncture according to method of manufacture stimulation to corresponding points, Kan-su$(BL_8)$ and Ki-mun($LR_{14}$), and carried out hematological, serological examination and electromicroscopical obseration. WBC level was decreased significantly in the experimental groups at 24 and 48 hours as compared with the control group. ${\gamma}-GTP$ level was decreased significantly in the experimental groups at 24 and 48 hours as compared with the control group. GPT level was decreased significantly in the experimental groups at 24 and 96 hours as compared with the control group, but GOT level did not reeveal any statistical difference. At 24-hours group, the cell organelles of the hepatic cells are destructed. The cisternae of the smooth endoplasmic reticulum are particulary dilated in the 24-hours control group compared with experimental group. At 48-hours group, the destructed cell organelles are recovered in the experimental group compared with control group. At 96-hours group, the cell organelles of hepatic cells are showing feture of normal group. According to the above findings, it is considered that Moschus, Bovis Calculus, Ursi Fel aqua-acupuncture has effects of recovery of acutely damaged liver.

• Journal of Acupuncture Research
• /
• 제15권2호
• /
• pp.331-348
• /
• 1998

Purpose: In order to study the therapeutic effect of TBR(Smilacis glabrae Rhizoma) aqua-acupuncture on the $HgCI_2$(mercury bichloride) intoxicated kidneys of rats. Methods: 10% TBR extract solution was aqua-punctured into the bilateral loci of Shin-su(BL23), every other day for 18 days, and the amount of leucocytes, erythrocytes, thrombocytes, hematocrit, hemoglobin, serum BUN and creatinine levels were measured and renal mercury level and histopathological findings were studied as well. The experimental groups were into nonmaI group, control group, sample I group, sample II group and sample III group. Results: 1. There were not any significant changes of leucocytes, erythrocytes and serum creatinine level in the TBR aqua-acupuncture group, saline aqua-acupuncture group and TBR aqua-acupuncture group respectively as compared with control group. 2. It showed a significant increase of hematocrit and hemoglobin level in the TBR aqua-acupuncture group on the 8th experimental day as compared with the control group. 3. It showed a significant increase of platelet in the TBR aqua-acupuncture group on the 8th experimental day, whereas significant decreases on the 18th experimental day as compared with the control group. 4. It showed a significant decrease of serum BUN level in the TBR aqua-acupuncture group on the 8th and 18th experimental day as compared with the control group. 5. It showed a significant decrease of renal mercury level in the TBR aqua-acupuncture group on compared with the control group. 6. In the histopathological findings, TBR aqua-acupuncture group showed slight atrophy of the renal tubules, mitosis and regeneration of tubular lining cells with visible nuclei, whereas the control group showed acute tubular necrosis, especially severe necrosis of tubular epithelial cells. Conclusions: Smilacis glabrae Rhizoma aqua-acupuncture on injured kidneys Induced by HgCl2 Intoxication in Rats increases hematocrit, hemoglobin and platelet level, and decreases BUN, renal mercury level. This suggests that Smilacis glabrae Rhizoma aqua-acupuncture helps to recover kidney from HgCl2 intoxication.

• 한방재활의학과학회지
• /
• 제15권2호
• /
• pp.1-16
• /
• 2005

Objectives : This experimental study was designed to investigate the effects of EjinTang-Gamybang(Erchentang-jiaweifang ; ETG) on the change of some values related to obesity and observe the complications coming from obesity in obese rat induced by high fat diet. Methods : Experimental group were as follows ; normal group were fed normal diet and administered DDW $1.0m{\ell}$ to rat during 7 weeks, control group were fed high fat diet and administered DDW $1.0m{\ell}$ during 7 weeks, sample A were fed high fat diet and administered ETG 500 mg/kg $1.0m{\ell}$ during 7 weeks, sample B were fed high fat diet and administered ETG 700 mg/kg $1.0m{\ell}$ during 7 weeks. Results & Conclusions : 1. Sample A and Sample B significantly decreased body weight, serum LDL-cholesterol level, serum free fatty acid level, serum total lipid level, serum phospholipid level and serum leptin level in comparison with control group. 2. Sample B significantly decreased serum total cholesterol level and serum triglyceride level in comparison with control group. 3. Sample B significantly increased serum HDL-cholesterol level in comparison with control group. According to above results, the author suggested that ETG was able to be used for the herbal medication of obesity. 4. ETG significantly increased rCBF, and increased CMF in a dose-dependent. 5. ETG significantly decreased MABP in a dose-dependent. 6. rCBF was significantly and stably increased by ETG(10 mg/kg, i.p.) during the period of cerebral reperfusion, which contrasted with the findings of rapid and marked increase in control group. This results were suggested that ETG significantly increased rCBF by dilating arterial diameter and activating serum leptin level. So that, the present author thought that ETG had an effects of obesity and complication coming from obesity(ischemic cerebral and cardiac disease).

• Journal of Korean Biological Nursing Science
• /
• 제1권1호
• /
• pp.100-114
• /
• 1999

This study was done to investigate the effects of rapidly-rotating shift work of two-day interval on fatigue level and the concentration of urinary 17-KS, $Na^+,\;Cl^-$. The subjects were 20 nursing college students(control group) and 15 nurses in a university hospital and the study was done from Apr. 21 to May 4th, 1999. In the test group, each 5 nurses were allocated to day shift(8 AM-4 PM), evening shift(4 PM-12 MN) and night shift(12 MN-8 AM) respectively. The fatigue level were measured 30 minutes after work start on the 2nd day of work shift. Urine specimens were collected at 8 AM, 4 PM and 12 MN on the 2nd day of work shift in the control group and 30 minutes before and after work on the 2nd day of work shift in the test group. The data were analyzed with SPSS(for Window, ver 7.5). Statistical analysis was performed by using t-test, paired t-test and ANOVA. The results were as follows. 1. The perceived fatigue level in shift work 1) The physical and mental fatigue level were significantly higher in night shift than that in day or evening shift(p<0.05). In the neuro-sensory fatigue level, night shift showed higher tendency than that in day or evening shift, but there were no significant differences between each shifts. 2) Comparison between the control group and the test group: Physical fatigue level was significantly higher in night shift than that in day or evening shift of the control group(P<.001). Mental fatigue level was significantly higher in day or night shift than that in evening shift of the control group(P<.05). In the neuro-sensory fatigue level, test group showed higher tendency than that in the control group, but there were no significant differences between two groups. 3) The total fatigue level was higher in night shift than that in day shift or evening shift(P<.05). In comparing with the control group, night shift and day shift showed higher total fatigue level than that in the control group(p<0.05). 2. The concentration of urinary 17-KS, $Na^+$ and $Cl^-$ In the control group, urinary 17-KS, $Na^+$ and $Cl^-$ showed higher level in afternoon that in morning and night. In the test group, cr in day and evening shift and $Na^+$ in evening shift showed higher level at the end of work. The 17-KS concentration at the begining and the end of work in three shift groups were lower than those in control group(p<0.05), however, $Cl^-$ concentration at the begining of work in day shift, and the end of work in day and evening shift were higher than those in control group(p<0.05). $Cl^-$ concentration at the begining and end of work in night shift were considerably higher than those in control group repectively(p<0.1, p<001). $Na^+$ concentration showed a higher tendency in three shift groups except at the begining of work in night shift, but there were no statistical difference. In comparing concentration of the 17-KS, $Na^+$ and $Cl^-$ among the shift groups, 17-KS concentration showed a lower tendency and $Na^+,\;Cl^-$ showed a higher tendency in night shift: The result of this study showes that biorhythm of shift work nurse was irregular. Fatigue level as the subjective index for evaluating the health problem concerning shift work was higher in night shift and proved to be in accordance with the concentration of urinary 17-KS, $Na^+$ and $Cl^-$ used as objective indices. Disturbation of biorhythm and work stress due to night shift seems to cause the health problem of nurses and decrease of work efficiency. It is considered that work regualtion is necessary for the rational management of the nursing administration.

• 한국컴퓨터정보학회논문지
• /
• 제27권6호
• /
• pp.139-147
• /
• 2022

본 연구는 신체활동수준, 주관적 건강상태, 코로나19 염려의 관계를 분석하는 것에 목적이 있다. 이를 위하여 2020년 지역사회건강조사를 바탕으로 전국 만 19세 이상 성인 229,269명의 설문데이터 자료를 분석하였다. 복합표본설계로 가중치, 층화변수, 집락변수를 지정하여 분석하였다. SPSS 통계분석 프로그램을 이용하여 복합표본 빈도분석, 복합표본 교차분석, 복합표본 회귀분석을 실시하고, 다음과 같은 결과를 얻었다. 첫째, 신체활동수준이 높은 그룹이 신체활동수준이 낮은 그룹에 비하여 주관적 건강상태가 높은 것으로 나타났다. 둘째, 신체활동수준이 높은 그룹이 신체활동수준이 낮은 그룹에 비하여 코로나19 염려가 낮은 것으로 나타났다. 셋째, 주관적 건강수준이 높은 그룹이 낮은 그룹에 비하여 코로나19 염려가 낮은 것으로 나타났다. 다만 본 연구에서는 실제 코로나19 감염여부는 분석에 포함하지 않았다는 제한점이 있다.

• 치과방사선
• /
• 제23권2호
• /
• pp.215-226
• /
• 1993

The purpose of this study was to investigate the effects of the low level irradiation on the mitotic index of the basal cells in the buccal pouch of hamsters{golden hamster: APG strain). After colchicine was administrated to the hamsters through the intraperitoneal, the low level radiation{5460mR) was exposed on the buccal pouch of hamsters. The mitotic index of the basal cells was estimated 2 hours after irradiation. The results were as follows: 1. The mean mitotic index of the control group was 4.32. 2. The mean mitotic index of the irradiated group was 2.46. 3. T-test of data in the irradiated group showed significant difference from the mitotic index in the control group. These results suggested the lowered mitotic index of the irradiated group resulted from the low level irradiation.

• 대한물리치료과학회지
• /
• 제10권2호
• /
• pp.73-85
• /
• 2003

The purpose of the present study was to the investigate the effect of sports massage, kaltenborn-evjenth orthopedic manipulative therapy and electrical therapy, general exercise on the limitation of range of motion(ROM) and on the pain(VAS) in patients with frozen shoulder. Fiftheen frozen shoulder patients between 50 and 60 years of age(females) were selected and were divided equally by random distribution into A group(sports massage, kaltenborn-evjenth orthopedic manipulative therapy, N=7)and B(electrical therapy, general exercise therapy, N=7) group. The results obtained were as follows : 1) The range of motion between two groups are significantly different in the treatment times, the ROM of A group increase in after-treatment(2 week 4 week) in comparison with ROM in before-treatment, it is significant increase. And it is significant difference in B group. 2) The pain level between two groups are not significantly different in the treatment times, the pain level of A group decrease in after-treatment(2 week, 4 week) in comparison with before-treatment, it is significant decrease. And it is significant difference in B group. Although the pain level of the A group decrease in after 2 week treatment in comparison with before-treatment but it is not significant decrease. Although the pain level of the B group decrease in after 4 week treatment in comparison with after 2 week treatment, but it is not significant decrease. 3) The A group is more effective in increasing the ROM and decreasing the pain level than B group during treatment times. The results showed that both A group method and B group method are effective ROM increase and pain reduce, but A group method is superior to B group method in ROM increase and pain reduce.

• Journal of Nutrition and Health
• /
• 제34권3호
• /
• pp.299-305
• /
• 2001

The purpose of this study was to investigate the effects of catechin on the changes of microsomal mixed function oxidase(MFO) system and oxidative damage in rat liver exposed to microwave. Sprague-Dawley male rats weighing 200$\pm$10g body weight were randomly assigned to one normal and microwave exposed groups: microwave exposed groups were divided three groups: catechin free diet(MW) group, 0.25% catechin(MW+0.25C) group and 0.5% catechin(MW+0.5C) group to the levels of dietary catechin supplementation. The rats were irradiated with microwave at frequency 2.45GHz for 15 min and then the changes pattern of mixed function oxidase system and oxidative damage were investigated for 16 days. The activity of XOD in MW group was increased from 4 day to 8 days after irradiation, compared to normal group and decreased to the level of normal group 16 days. But catechin supplementation group were maintained to the normal level. The contents of cytochrome P(sub)450 and NADPH cytochrome P(sub)450 reductase activities in liver of MW group was increased from 4 day to 8 day after irradiation, compared to normal group and decreased to the level of normal group at 16 day. But catechin supplementation group were recovered to the normal level. The contents of superoxide radical in liver of MW group was increased 1.28, 1.25, 1.17 fold of normal group at 4,6 and 8 days days after irradiation. respectively, but catechin supplementation group were maintained the normal level. The contents of lipifuscin in liver have a same tendency in superoxide radical contents. These result suggested that the supplementation of catechin have control the mixed function oxidase system and oxidative damage and that may help to recover tissues from microwave damage. (Korean J Nutrition 34(3) : 299~305, 2001)

• 한국초등수학교육학회지
• /
• 제14권3호
• /
• pp.907-935
• /
• 2010

본 연구는 개방형 문제를 이용한 수준별 학습이 학업성취도에 미치는 효과와 개방형 문제를 해결하는 과정에서 학생들이 보인 창의적인 반응을 분석하여 수학과 교수 학습 방법의 개선에 도움을 주는데 그 목적이 있다. 이러한 연구 목적을 위해 첫째, 개방형 문제를 활용한 수준별 학습과 일반적인 형태의 수준별 학습 사이에 성취도의 차이가 있는가?, 둘째, 개방형 문제를 활용한 수준별 학습은 실험집단의 성취도별 상 중 하 집단 중 어느 집단에게 더 효과가 있는가?, 셋째, 개방형 문제를 활용한 수준별 학습 과정에서 나타난 학생들의 반응은 어떠한가? 를 연구문제로 설정하였다. 연구를 위해 대전광역시 소재 S초등학교 3학년 두 학급을 실험집단과 비교집단으로 선정하였다. 연구문제 1을 위하여 두 집단의 사전 성취도 검사를 실시하여 동질성을 확인한 후 비교집단은 일반적인 형태의 수준별 학습을, 실험집단은 개방형 문제를 활용한 수준별 학습 후 사후검사를 실시하였다. 연구문제 2를 알아보기 위하여 실험반의 사전 검사 결과로 상(28%), 중(41%), 하(31%) 집단을 선정하였다. 실험처치 후 실시한 사후 검사에서 대응표본의 평균을 비교하여 어느 집단에 가장 효과가 있는지 알아보았다. 연구문제 3을 해결하기 위하여 개방형 문제를 이용한 수준별 학습을 한 집단에서 보인 반응을 분석하고, 전체토의 및 면담결과, 개방형 문제를 활용한 학습이 실제로 학생들의 반응에 어떤 영향을 미치는지 살펴보았다. 연구를 통해 다음과 같은 결과를 얻을 수 있었다. 첫째, 개방형 문제를 활용한 수준별 학습은 학업성취도에 긍정적인 영향을 미쳤다. 둘째, 개방형 문제를 활용한 수준별 학습은 학업 성취 수준 '하'집단에게 가장 효과가 높은 것으로 나타났다. 셋째, 개방형 문제를 해결하는 과정에서 학생들은 창의적이고 다양한 반응을 보였다.

• 한국식품영양과학회지
• /
• 제3권1호
• /
• pp.7-11
• /
• 1974

Wistar Strain male rats were divided into four different diet groups and the control group was fed on seven percent casein diet (C), the second with a mixture of 80% of rice and 20% of buckwheat (RW), the third with rice only (R), and the fourth with a mixture of rice and buckwheat of equal nitrogen level (RWS). Each diet group consisted of six rats was fed for three weeks by the adlibitum feeding method. The results of the experiment, i, e, the growth gain and change in the level of branch-amino acids in the plasma determined by the micro-bioassay method were as follows. 1. The group C showed the largest growth gain and the rest did in the order of RW group, R group, and RWS group. 2. It was shown that rats fed on diet of higher protein score tend to have higher level of free branch-amino acids in the plasma. 3. Thus, the protein score may be estimated based on the level of the free branch-amino acids in the plasma.