A STUDY OF THE LOW LEVEL RADIATION EFFECT ON THE MITOTIC INDEX OF THE BASAL CELLS IN THE BUCCAL POUCH OF HAMSTERS

저선량방사선이 햄스터의 협낭 기저세포 분열지수에 미치는 영향에 관한 연구

  • Kang Byung-Cheol (Department of Oral and Maxillofacial Radiology, College of Dentistry, Seoul National University) ;
  • You Dong-Soo (Department of Oral and Maxillofacial Radiology, College of Dentistry, Seoul National University)
  • 강병철 (서울대학교 치과대학 구강악안면방사선학 교실) ;
  • 유동수 (서울대학교 치과대학 구강악안면방사선학 교실)
  • Published : 1993.12.01

Abstract

The purpose of this study was to investigate the effects of the low level irradiation on the mitotic index of the basal cells in the buccal pouch of hamsters{golden hamster: APG strain). After colchicine was administrated to the hamsters through the intraperitoneal, the low level radiation{5460mR) was exposed on the buccal pouch of hamsters. The mitotic index of the basal cells was estimated 2 hours after irradiation. The results were as follows: 1. The mean mitotic index of the control group was 4.32. 2. The mean mitotic index of the irradiated group was 2.46. 3. T-test of data in the irradiated group showed significant difference from the mitotic index in the control group. These results suggested the lowered mitotic index of the irradiated group resulted from the low level irradiation.

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