• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.23 no.5
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• pp.428-434
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• 2014

Measurement of the absolute displacement of the moving machinery components in three-dimensions (3D) is of critical functional importance. This paper describes the system that measures motion associated with six degrees-of-freedom in 3D. Wire-sensors are used to estimate the positions of an object in a 3D Cartesian coordinate system, based on the values of their initial position and the measured values. For inducing the transfer function, which represents the motion of an object, the number of the minimum measurement points is determined. Also, the experimental measuring device is configured to visualize the behavior of a rectangular object in real-time. The software for measuring the six types of motions is directly programmed using a commercial software.

• Proceedings of the ESK Conference
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• 1994.04a
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• pp.75-84
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• 1994

A control panel layout method based on the constraint satisfaction problem(CSP) technique was developed to generate an ergonomically sound panel design. This control panel layout method attempts to incorporate a variety of relevant ergonomic principles and design constrains, and generate an optimal or, at least, a "satisfactory" solution through the efficient search algorithm. The problem of seeking an ergonomically sound panel design should be viewed as a multiple criteria problem, and most of the design objectives should be understood as constraints. Hence, a CSP technique was employed in this study for dealing with the multi-constraiants layout problem. The efficient search algorithm using "preprocess" and "look ahead" procedures was developed to handle the vast amount of computational effort. In order to apply the CSP technique to the panel layout procedure, the ergonomic principles such as spatial compatibility, frequency-of- use, importance, functional grouping, and sequence-of-use were formalized as CSP terms. The effectiveness of the developed panel layout method was evaluated by example problems, and the results clearly showed that the generated layouts took various ergonomic design principles into account.esign principles into account.

• Journal of the Korea Safety Management & Science
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• v.13 no.1
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• pp.203-209
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• 2011

This study develops three new models that are practically applicable to three stages of Taguchi's robust design, which includes system design, parameter design and tolerance design. In system design, the Multiple Loss Function Analysis(MLFA) and Overall Loss Index(OLI) which reflect upon weight of characteristics and importance of specification are developed. Moreover parameter design presents Process Capability Index(PCI), $C_{PUK}$ and $C_{PLK}$, in order to segregate Signal-To-Noise Ratio(SNR) into accuracy and precision for an evaluation of relative comparison. In addition, tolerance design presents the new model of allowance computation for assembled product which is primarily derived from safety margin(SM) considering functional limit and specification. The guideline of those three new models, which include systematic charts and applicable illustrations, offers convenience for practitioners in the field. Hence, the practical applications could be made with the steps of robust designs such as system design, parameter design and specification allowance design.

• Speech Sciences
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• v.1
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• pp.261-274
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• 1997

In spite of the presumed importance of the strap muscles on laryngeal valving and speech production, there is little research concerning the physiological role and the functional differences among the strap muscles. Generally, the strap muscles have been shown to cause a decrease in the fundamental frequency(Fo) of phonation during contraction. In this study, an in vivo canine laryngeal model was used to show the effects of strap muscles on the laryngeal function by measuring the Fo, subglottal pressure, vocal intensity, vocal fold length, cricothyroid distance, and vertical laryngeal movement. Results demonstrated that the contraction of sternohyoid and sternothyroid muscles corresponded to a rise in subglottal pressure, shortened cricothyroid distance, lengthened vocal fold, and raised Fo and vocal intensity. The thyrohyoid muscle corresponded to lowered subglottal pressure, widened cricothyroid distance, shortened vocal fold, and lowered Fo and vocal intensity. It was postulated that the mechanism of altering Fa and other variables after stimulation of the strap muscles is due to the effects of laryngotracheal pulling, upward or downward, and laryngotracheal forward bending, by the external forces during strap muscle contraction.

• Archives of Pharmacal Research
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• v.9 no.2
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• pp.63-73
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• 1986

The use of biodegradable polymetric materials as drug carriers is a relatively new dimension in polymeric drug delivery systems. A number of biodegradable or bioerodible polymers, such as poly(lactic/glycolic acid) copolymer, poly($\alpha$-amino acid), polyanhydride, and poly (ortho ester) are currently being investigated for this purpose. These polymers are useful for matrix and reservoir-type delivery devices. In addition, when chemical functional groups are introduced to the biodegradable polymer backdone, such as poly (N-(2-hydroxypropyl) methacrylamide), the therapeutic agent can be covalently bound directly or via spacer to the backbone polymer. These polymer/drug conjugates represent another new dimension in biodegradable polymeric drug delivery systems. In addition, examples of biodegradable polymeric durg delivery systems currently being investigated will be discussed for the purpose of demonstrarting the potential importance of this new field.

• Molecules and Cells
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• v.40 no.1
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• pp.10-16
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• 2017

When peripheral axons are damaged, neuronal injury signaling pathways induce transcriptional changes that support axon regeneration and consequent functional recovery. The recent development of bioinformatics techniques has allowed for the identification of many of the regeneration-associated genes that are regulated by neural injury, yet it remains unclear how global changes in transcriptome are coordinated. In this article, we review recent studies on the epigenetic mechanisms orchestrating changes in gene expression in response to nerve injury. We highlight the importance of epigenetic mechanisms in discriminating efficient axon regeneration in the peripheral nervous system and very limited axon regrowth in the central nervous system and discuss the therapeutic potential of targeting epigenetic regulators to improve neural recovery.

• Journal of Sensor Science and Technology
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• v.24 no.5
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• pp.281-286
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• 2015

The importance of air quality monitoring is rapidly increasing. Even though state-of-the-art air quality monitoring technologies such as mass spectrometry, gas chromatography, and optical measurement enable high-fidelity measurement of air pollutants, they cannot be widely used for portable or personalized platforms because of their high cost and complexity. Recently, personalized and localized environmental monitoring, rather than global and averaged environmental monitoring, has drawn greater attention with the advancement of mobile telecommunication technologies. Here, micro- and nano-technologies enable highly integrated and ultra-compact sensors to meet the needs of personalized environmental monitoring. In this paper, several examples of MEMS-based gas sensors for compact and personalized air quality monitoring are explained. Additionally, the principles and usage of functional nanomaterials are discussed for highly sensitive and selective gas sensors.

• IE interfaces
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• v.13 no.2
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• pp.234-245
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• 2000

In this paper, the conceptual framework of IBS(Intelligent Building Systems) is redefined, and we propose two ANP(Analytic Network Process) models for ranking IBS. Traditional models have ranked IBS according to technical features or the number of elements in IBS. But, we consider relative functional importance among IBS elements for efficient building operation. According to the structure of interactive-relationship among IBS elements, we present two types of model. The one is Model A that is composed of both hierarchical and network structures. It has $12{\times}12$ supermatrix consists of interdependent relationship between 6 benefit elements(Productivity, Saving, Safety, Convenience, Pleasantness, Environment Affinity) and 6 IBS elements(Building Operation, Security, Safety, Telecommunication(TC), Office Automation(OA), other elements). Each of 6 IBS elements has subelements in hierarchical structure. The other is Model B that has $25{\times}25$ supermatrix consists of interdependent relationship between 6 benefit elements and 19 IBS sub elements. Merits and demerits of each model are discussed in detail.

• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.1371-1373
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• 2003

The importance of Fundamental Geographical Information Framework for Digital City (FGFDC) is analysed, it provides all city agencies and units with uniform geographic references. Six kind of data are chosen as the core data sets of a FGDC, a web-based distributed mechanism is constructed to promote data sharing among different agencies. Elementary functional requirements of FGDC are analyzed, so that it can serve as a common distributed urban GIS. A practical FGFDC is developed for Yangzhou Development Administrative Region, and an 3D visualization system is developed within this framework.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.11a
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• pp.388-392
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• 2008

Research of methods for preventing accidents and minimizing losses during the liquid rocket engine (LRE) test and its exploration is of current importance. In this paper the steps of progress to LRE accidents are defined, and methods for preventing LRE accidents and minimizing losses from accidents are considered. The suggested methods in this paper can be applied to LRE test and exploration for protecting engine system from emergency situation.