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Applications of proportional odds ordinal logistic regression models and continuation ratio models in examining the association of physical inactivity with erectile dysfunction among type 2 diabetic patients

  • Mathew, Anil C.;Siby, Elbin;Tom, Amal;Kumar R, Senthil
    • Korean Journal of Exercise Nutrition
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    • v.25 no.1
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    • pp.30-34
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    • 2021
  • [Purpose] Many studies have observed a high prevalence of erectile dysfunction among individuals performing physical activity in less leisure-time. However, this relationship in patients with type 2 diabetic patients is not well studied. In exposure outcome studies with ordinal outcome variables, investigators often try to make the outcome variable dichotomous and lose information by collapsing categories. Several statistical models have been developed to make full use of all information in ordinal response data, but they have not been widely used in public health research. In this paper, we discuss the application of two statistical models to determine the association of physical inactivity with erectile dysfunction among patients with type 2 diabetes. [Methods] A total of 204 married men aged 20-60 years with a diagnosis of type 2 diabetes at the outpatient unit of the Department of Endocrinology at PSG hospitals during the months of May and June 2019 were studied. We examined the association between physical inactivity and erectile dysfunction using proportional odds ordinal logistic regression models and continuation ratio models. [Results] The proportional odds model revealed that patients with diabetes who perform leisure time physical activity for over 40 minutes per day have reduced odds of erectile dysfunction (odds ratio=0.38) across the severity categories of erectile dysfunction after adjusting for age and duration of diabetes. [Conclusion] The present study suggests that physical inactivity has a negative impact on erectile function. We observed that the simple logistic regression model had only 75% efficiency compared to the proportional odds model used here; hence, more valid estimates were obtained here.

The Significance of Gonadotropin Ratio in In Vitro Fertilization of Human Oocytes (성선 자극호르몬의 비율이 인간난자의 체외수정에 미치는 영향에 관한 연구)

  • Moon, Shin-Yong
    • Clinical and Experimental Reproductive Medicine
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    • v.15 no.2
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    • pp.135-147
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    • 1988
  • To compare the stimulation effect of the ratio in follicle stimulating hormone and luteinizing hormone in induction of multiple follicular growth, the serum $E_2$ level, the diameter of follicle, number of aspirated follicles and cleavage rate of in vitro fertilized preovulatory oocytes as well as the pregnancy rate were evaluated. Forty one patients with irreparable tubal disease were stimulated by hMG(n=24) or FSH/hMG(n=17) for the purpose of in vitro fertilization and embryo transfer. The following results were obtained. 1. Serum estradiol($E_2$) levels on the day of hCG administration were $921.0{\pm}353.3\;pg/ml$ in hMG group and $1272.9{\pm}1060.6\;pg/ml$ in FSH/hMG group. The serum $E_2$ value of hMG group was significantly lower than that of FSH/hMG group. 2. The diameter of leading follicle by ultrasonogram on the day of hCG administration were $16.2{\pm}2.0\;mm$ in hMG group and $16.2{\pm}2.6\;mm$ in FSH/hMG group. No significant difference of follicle diameter between two groups was demonstrated. 3. The number of follicles with diameter above 10 mm by sonogram on the day of hCG injection were $3.91{\pm}2.32$ in hMG group and $6.52{\pm}3.86$ in FSH/hMG group. There was significant difference of number of follicles between two groups, (p< 0.01). 4. The number of oocytes found per patient at aspiration were $2.59{\pm}1.00$ in hMG group and 3. $76{\pm}2.31$ in FSH/hMG group. There was significant difference of number of aspirated oocytes between two groups. (p< 0.05). 5. The detection rate of preovulatory oocyte at aspiration were 68.4%(39/57) in hMG group (n=22) and 77.6%(38/49) in FSH/hMG group (n=13). 6. The cleavage rate of preovulatory oocyte at 44 hours after insemination were 74.4%(29/39) in hMG group(n=22) and 81.6%(31/38) in FSH/hMG group (n=13). When only hMG was used, one pregnancy was established in 15 patients to whom 29 zygotes were transferred. And a full term normal female baby was delivered by elective cesarean section. In the FSH/hMG group, five pregnancies out of 9 transferred patients were confirmed by serum ${\beta}-hCG$. Two pregnancies were spontaneously aborted before the 6th week of pregnancy. One patient aborted her baby at the 18th week of pregnancy because of incompetent internal os of the cervix. Two patients delivered two full term babies by elective cesarean section. From the above findings, paralell with the increase in the ratio of exogenous follicle stimulating hormone to luteinizing hormone, an increase in oocyte recovery was observed as well as an improvements in pregnancy rate. It was concluded that FSH enrichment early in the follicular phase had a beneficial effect in the controlled ovarian hyperstimulation.

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A Study on Beam-to-Column Connections with Plate Type Energy Absorption System (플레이트형 에너지 흡수장치를 가지는 기둥-보 접합부에 관한 연구)

  • Oh, Sang Hoon;Park, Hae Yong
    • Journal of Korean Society of Steel Construction
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    • v.25 no.1
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    • pp.103-114
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    • 2013
  • Recently, there is a growing interest on sustainable connection system that makes it possible to reuse of main structural members by concentrating most of the damage in the frame caused by strong horizontal force, such as earthquake, to damper. In this study proposed a new type of damage-controlled connection system applying these concepts and analysed the major structural performance of the proposed system through the full-scale cyclic loading test and nonlinear finite element analyses. According to the result, it derived the optimal damper/beam strength ratio that minimize the damage of main members and satisfy at least the fully plastic moment of the beam. And it was to verify the possibility of applying as seismic connection details.

Shear Cracking of Prestressed Girders with High Strength Concrete

  • Labib, Emad L.;Mo, Y.L.;Hsu, Thomas T.C.
    • International Journal of Concrete Structures and Materials
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    • v.7 no.1
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    • pp.71-78
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    • 2013
  • Prestressed concrete (PC) is the predominant material in highway bridge construction. The use of high-strength concrete has gained wide acceptance in the PC industry. The main target in the highway industry is to increase the durability and the life-span of bridges. Cracking of elements is one aspect which affects durability. Recently, nine 7.62 meter long PC I-beams made with different concrete strength were designed according to a simple, semi-empirical equation developed at the University of Houston (UH) (Laskar et al., ACI Journal 107(3): 330-339, 2010). The UH Method is a function of shear span-to-depth ratio (a/d), concrete strength $\sqrt{f^{\prime}_c}$, web area $b_wd$, and amount of transverse steel. Based on testing these girders, the shear cracking strength of girders with different concrete strength and different shear span-to-depth ratio was investigated and compared to the available approaches in current codes such as ACI 318-11 (2011) and AASHTO LRFD Specifications (2010).

Analysis of Design and Operation Performance of Micro Gas Turbine : Part 2 - Variations in Engine's Operation and Performance Caused by Performance Degradation of Compressor and Turbine (마이크로 가스터빈 설계 및 운전 성능 분석 : 제2부 - 압축기와 터빈 성능저하에 의한 엔진 운전 및 성능변화)

  • Kim, Jeong Ho;Kim, Min Jae;Kim, Tong Seop
    • The KSFM Journal of Fluid Machinery
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    • v.18 no.4
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    • pp.30-35
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    • 2015
  • This study analyzed the variations in the performance and operation of a 200 kW class micro gas turbine according to performance degradation of compressor and turbine. An in-house code, developed by the present authors and presented in the first part of these series of papers, were used for the analysis. The degradation of compressor and turbine were simulated by modifications in the their performance maps: mass flow rate, pressure ratio and efficiency were decreased from the reference values. Firstly, the variations in the operating conditions (air flow rate, pressure ratio) were predicted for the full load condition. Then, the same analysis were performed for a wide partial load operating range. The change in engine's performance (power output and efficiency) due to the component degradation was predicted. In addition, the change in the compressor surge margin, which is an important indicator for safe engine operation, was evaluated.

The IGRINS Spectra of Late-Type Stars

  • Park, Sunkyung;Lee, Jeong-Eun;Kang, Wonseok;Lee, Sang-Gak;Chun, Moo-Young;Kim, Kang-Min;Yuk, In-Soo;Jeong, Ueejeong;Jaffe, Daniel T.
    • The Bulletin of The Korean Astronomical Society
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    • v.40 no.2
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    • pp.58.2-58.2
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    • 2015
  • We present a library of high spectral resolution (R ~ 40,000) and high signal-to-noise ratio (S/N ~ 200) near-infrared spectra of ~50 late-type stars. The spectra of late-type stars were obtained with Immersion GRating INfrared Spectrograph (IGRINS) covering the full H and K band. The stars are mainly from MK standard stars which have well-defined spectral types and luminosity classes and cover wide ranges of effective temperatures and surface gravities. The spectra are corrected for telluric absorption lines and absolutely flux calibrated using the Two Micron All Sky Survey (2MASS) photometry. In this work, we present the preliminary results of spectroscopic diagnostics for stellar physical parameters. Our ultimate goal is to provide a library of near-infrared spectra of standard stars, which covers all spectral types and luminosity classes, with a high spectral resolution and high signal-to-noise ratio.

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VIDEO TRAFFIC MODELING BASED ON $GEO^Y/G/{\infty}$ INPUT PROCESSES

  • Kang, Sang-Hyuk;Kim, Ba-Ra
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.12 no.3
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    • pp.171-190
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    • 2008
  • With growing applications of wireless video streaming, an efficient video traffic model featuring modern high-compression techniques is more desirable than ever, because the wireless channel bandwidths are ever limited and time-varying. We propose a modeling and analysis method for video traffic by a class of stochastic processes, which we call '$GEO^Y/G/{\infty}$ input processes'. We model video traffic by $GEO^Y/G/{\infty}$ input process with gamma-distributed batch sizes Y and Weibull-like autocorrelation function. Using four real-encoded, full-length video traces including action movies, a drama, and an animation, we evaluate our modeling performance against existing model, transformed-M/G/${\infty}$ input process, which is one of most recently proposed video modeling methods in the literature. Our proposed $GEO^Y/G/{\infty}$ model is observed to consistently provide conservative performance predictions, in terms of packet loss ratio, within acceptable error at various traffic loads of interest in practical multimedia streaming systems, while the existing transformed-M/G/${\infty}$ fails. For real-time implementation of our model, we analyze G/D/1/K queueing systems with $GEO^Y/G/{\infty}$ input process to upper estimate the packet loss probabilities.

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A study on the Early Postoperative Hemodynamic Changes after Correction of Congenital Heart Defects associated with Pulmonary Hypertension (폐동맥고혈압증을 동반한 선천성 심기형 환아들에서 술후 조기 혈류역학적 변화에 대한 연구)

  • Kim, Yong-Jin;Kim, Gi-Bong
    • Journal of Chest Surgery
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    • v.23 no.1
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    • pp.32-40
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    • 1990
  • Surgical correction of congenital cardiac defects in infants and children with an elevated pulmonary arterial pressure or pulmonary vascular resistance carries a significant early postoperative mortality. And accurate assessments of cardiac output is critically important in these patients. From April 1988 through September 1989, serial measurements of cardiac index, ratio of pulmonary-systemic systolic pressure, ratio of pulmonary-systemic resistance, central venous pressure, left atrial pressure, and urine output during the first 48 hours after the cardiac operation were made in 30 congenital cardiac defects associated with pulmonary hypertension. Cardiac index showed significant increase only after 24 hour postoperatively and this low cardiac performance in the early postoperative period should be considered when postoperative management is being planned in the risky patients. There were no variables which showed any significant correlation with cardiac index. In 12 cases[40%], pulmonary hypertensive crisis developed during the 48 hours postoperatively, and they were treated with full sedation, hyperventilation with 100 % 0y and pulmonary vasodilator infusion. In all patient with preoperative pulmonary hypertension, surgical placement of a pulmonary artery catheter is desirable to allow prompt diagnosis of pulmonary hypertensive crisis and to monitor subsequent therapy.

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Simulation of Stage-Storage Curve Function in Irrigation Reservoirs (저수지 내용적 곡선의 모의발생)

  • 김현영;윤인택;최용선;오수훈
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.37 no.5
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    • pp.73-80
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    • 1995
  • The uses of stage-storage curve function are diverse in irrigation reservoirs. The curve functions would be used to determine the optimal size of spillway length and the inundation area above full water level based on the flood routing in reservoirs. In addition, the curve function would he used to transform the stage to the storage for the reservoir water management, in which the storage is the supply water. Besides those, the curve is necessary for the planning of dredging, the estimation of the effective and the dead storage, the drought management by reservoir, etc. The curve function data, however, are almost unavailable for these purposes. According to the statistics, about 74% of the 2, 900 resevoirs which are maintained by Farm Land Improvement Association have no more effective data. Therefore, the simulation of the curve function could be better alternative. The curve functions were simulated derivating the regression equations based on the basin relief ratio and the effective depth. The results of the verification show the enough reliability of the application to generate the curve function in some reservoirs which do not have the surveyed stage-storage data. Also, even though the averaged curve function would be applicated without the basin relief ratio data, the result shows that the simulated curve is closer to the real one than the linear function by only the existing effective storage data.

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New PCS Applied High Boost Ratio Dual Converter and Single Phase Half Bridge Inverter (고승압 듀얼 컨버터와 단상 하프 브릿지 인버터를 적용한 새로운 PCS)

  • Lee, Hee-Jun;Shin, Soo-Choel;Hyun, Seung-Wook;Jung, Yong-Chae;Won, Chung-Yuen
    • The Transactions of the Korean Institute of Power Electronics
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    • v.18 no.6
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    • pp.515-522
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    • 2013
  • In this paper, a new PCS is proposed which is consisted of high boost dual converter and single phase half-bridge inverter. The proposed PCS is configured in parallel input / serial output, using two interleaved voltage doubler converter. Converter of the proposed PCS is distribute input current by configuring parallel input and reduced turn ratio of transformer by configuring serial output. Also, compositions of the inverter are composed of serial output capacitor of converter and half-bridge inverter. The dual converter and single phase half-bridge inverter is designed and characteristic of the new PCS is analysed. The system of the 1.5[kW] PCS is verified through an experimental about operation and stability.