• Korean Journal of Family Social Work
• /
• no.23
• /
• pp.263-302
• /
• 2008

The study had four purposes as follows; First, the researcher tried to find the characteristics of conflict. Second, the researcher attempted to find the factors influencing the conflict between mother and the eldest son, Third, the study attempted to find the therapist's intervention techniques, which were caused the change of the conflict between mother and the eldest son. Lastly, the study was to find the changed contents of family relationships. The total family counseling was 13 sessions, which included individual and family counseling. The study used constant comparative analysis by using open coding method to find the factors. Also, the researcher used Miles and Huberman's matrix and graphical network display to show the relationships among factors influencing the conflicts between mother and the eldest son. The study found the boundary problem of family, family's undifferentiated ego, dysfunctional communication patterns, and mother's experience from family of origin as factors influencing the conflict between mother and the eldest son. On the other hand, the study found that the therapist used the formation of therapeutic alliance relationship, guide of communication skills, the reflection of repeated pattern, reframing and a metaphor as intervention methods. The result of study revealed that changed level of family relationship, activating functional communication, changed boundary among family members, differentiated ego of family members, and changed cognition as the changed contents of family relationship.

• Journal of Family Resource Management and Policy Review
• /
• v.27 no.2
• /
• pp.35-47
• /
• 2023

The purpose of this study was to understand family changes and dynamics of and to suggest institutional/policy-level tasks for coping with them, by paying attention to changing family values of single-person households and their caring work performed in everyday life. This study selected 11 single-person households residing in Ulsan by considering their age and marital status, and analyzed their overall daily lives, family values, and the characteristics of household work and caring. The characteristics of these single-person households in Ulsan, not only showed the coexistence of "simplicity, but instability" when maintaining and living their own lives, but also showed the ambivalent characteristics of family values by showing a gap between the perception and reality of diversity. In regard to family life, the participants complained of difficulties in "caring and relationship of family of origin" and the "economic factors", and notably showed the "dual value system". For a more stable life, the single-person households were forming social networks to relieve a sense of isolation and loneliness, and to recover relationships, instead of limiting themselves to only the traditional method of family formation. Thus, it would be possible to respond to family changes when changes are promoted in each area of "the perception of life", "family life", and the "family & social relationship", and this research suggests policy-level tasks based on the results of this study.

• Journal of the Korean Home Economics Association
• /
• v.44 no.3 s.217
• /
• pp.27-49
• /
• 2006

This study investigated the integrated effects of family, school, internet, and mass culture factors on the identity formation of adolescents. Specifically, the purposes of this study were to categorize adolescents into groups by what they do during the time except the life in school and to investigate differences among the groups regarding the identity information(body image, self-esteem, self-identity) and the influences of environmental factors on identity formation of adolescent. The study distributed questionnaires to middle and high school adolescents of five representative cities in South Korea. The total respondents were 2240(960 from Seoul/Kyongki, and 320 each from Taegu, Pusan, Kwangju, and Taejon). The response rate was 98.7%. The data were analyzed by factor analysis, cluster analysis, ANOVA, Duncan test, and multiple regression. The results showed that Korean adolescents were segmented into five groups : TV preference group, computer preference group, friends and family involvement group, homework and study preference group, and study institute involvement group). The five groups were significantly different in regard to body image pursuit, self-esteem, and self-identity. The body image pursuit, self-esteem, and self-identity of adolescents were significantly different in regard to each environmental factors, in each adolescent group.

• Molecules and Cells
• /
• v.37 no.4
• /
• pp.330-336
• /
• 2014

Thymosin beta4 (TB4) has multiple functions in cellular response in processes as diverse as embryonic organ development and the pathogeneses of disease, especially those associated with cardiac coronary vessels. However, the specific roles played by TB4 during heart valve development in vertebrates are largely unknown. Here, we identified a novel function of TB4 in endothelial-mesenchymal transformation (EMT) in cardiac valve endocardial cushions in zebrafish. The expressions of thymosin family members in developing zebrafish embryos were determined by whole mount in situ hybridization. Of the thymosin family members only zTB4 was expressed in the developing heart region. Cardiac valve development at 48 h post fertilization was defected in zebrafish TB4 (zTB4) morpholino-injected embryos (morphants). In zTB4 morphants, abnormal linear heart tube development was observed. The expressions of bone morphogenetic protein (BMP) 4, notch1b, and hyaluronic acid synthase (HAS) 2 genes were also markedly reduced in atrio-ventricular canal (AVC). Endocardial cells in the AVC region were stained with anti-Zn5 antibody reactive against Dm-grasp (an EMT marker) to observe EMT in developing cardiac valves in zTB4 morphants. EMT marker expression in valve endothelial cells was confirmed after transfection with TB4 siRNA in the presence of transforming growth factor ${\beta}$ ($TGF{\beta}$) by RT-PCR and immunofluorescent assay. Zn5-positive endocardial AVC cells were not observed in zTB4 morphants, and knockdown of TB4 suppressed TGF-${\beta}$-induced EMT in ovine valve endothelial cells. Taken together, our results demonstrate that TB4 plays a pivotal role in cardiac valve formation by increasing EMT.

• SUVANNABHUMI
• /
• v.8 no.2
• /
• pp.131-159
• /
• 2016

This qualitative study was designed to explore the definition of ethnic identity of the Dusuns in Brunei Darussalam from the perspective of Shamsul A.B.'s (1996) "everyday-defined" social reality. The purpose of this study was twofold. Firstly, by employing Phinney's (1996) formulation of ethnic identity, this study examined the existence of core components of ethnic identity, namely, ethnic self-identification, ethnic involvement, positive attitude towards ethnic group, and sense of belonging in the life of the Dusuns. Secondly, by utilizing Phinney's (1996) three-stage model of ethnic identity formation, this study investigated the relationship between core components and the formation process of ethnic identity. Twenty-six Dusun informants ranging in age from 8 to 80 years old were interviewed for the purpose of this study. The analysis of the interview data revealed that all core components exist and evolve in the life of the Dusuns. Different perspectives towards core components can also be identified across different age groups. Adult informants contested the relevance of ethnic involvement in view of socio-cultural transformations that occurred within the ethnic group, whereas younger Dusuns were not able to extend sense of belonging outside their family. These findings lead to the identification of family and historical contexts as influential factors that shape the ways the informants experienced the ethnic identity components. Further, the findings of this study indicate the relationship between core components and the formation process of ethnic identity. Sense of belonging and community is only evident in the experience of older informants, sufficient to help them reach the stage of achieving ethnic identity. This also shows a positive sequential relation between the stages in Phinney's ethnic identity model and the age of the informants. Interestingly, evidence on internalized sense of belonging reveals the fact that an individual could still attain ethnic identity achievement even without experiencing all components of ethnic identity. Once again, this study suggests contextual factors play a role in the stage progression of the Dusuns' ethnic identity.

• Korean Journal of Culture and Social Issue
• /
• v.10 no.2
• /
• pp.1-15
• /
• 2004

The drastically changing society has brought diverse types of families, and these diversities are changing the concept of the word 'family' itself. Inevitably, these changes cause different viewpoints among family members, developing into conflicts and social issues. In this paper, generational family problems, which are caused by changes within the family as a result of the variously, diversely changing society, are observed to suggest a resolution. Looking into the functional variety that today's structural change within a family demands, several positives changes described below have been observed; Firstly, the change in the way of interaction among family members; Secondly, the demand for continuance on relational functions including love, care, etc, as a psychological resource of family; Thirdly, the conversion from form's sake relationship to actual relationship; and Lastly, the usage of a clearer communications network. The interaction between the parent-children relationship, according to the changes in family life cycle, is also re-focused to seek resolutions for intergenerational conflicts. The results are as follows; Firstly, the changeability of various family types today must be accepted, and the functional aspects of changing families must be emphasized ; Secondly, the mutual-exchanging value of each generation must be accepted, strengthening relational functions between generations; Thirdly, it is necessary to refocus filial piety. In other words, though the intergenerational transmission of family functions may become the basis of lineage and clan formation, it won't be possible without interaction between generation.

• BMB Reports
• /
• v.48 no.5
• /
• pp.249-255
• /
• 2015

PTPRT/RPTPρ is the most recently isolated member of the type IIB receptor-type protein tyrosine phosphatase family and its expression is restricted to the nervous system. PTPRT plays a critical role in regulation of synaptic formation and neuronal development. When PTPRT was overexpressed in hippocampal neurons, synaptic formation and dendritic arborization were induced. On the other hand, knockdown of PTPRT decreased neuronal transmission and attenuated neuronal development. PTPRT strengthened neuronal synapses by forming homophilic trans dimers with each other and heterophilic cis complexes with neuronal adhesion molecules. Fyn tyrosine kinase regulated PTPRT activity through phosphorylation of tyrosine 912 within the membrane-proximal catalytic domain of PTPRT. Phosphorylation induced homophilic cis dimerization of PTPRT and resulted in the inhibition of phosphatase activity. BCR-Rac1 GAP and Syntaxin-binding protein were found as new endogenous substrates of PTPRT in rat brain. PTPRT induced polymerization of actin cytoskeleton that determined the morphologies of dendrites and spines by inhibiting BCR-Rac1 GAP activity. Additionally, PTPRT appeared to regulate neurotransmitter release through reinforcement of interactions between Syntaxin-binding protein and Syntaxin, a SNARE protein. In conclusion, PTPRT regulates synaptic function and neuronal development through interactions with neuronal adhesion molecules and the dephosphorylation of synaptic molecules. [BMB Reports 2015; 48(5): 249-255]

• Human Ecology Research
• /
• v.52 no.4
• /
• pp.355-369
• /
• 2014

The in-law relationship traditionally plays a major role in Korean marriages and families because parents-in-law prefer to stay with their son under the same roof. The recent spike in the number of intercultural matches in South Korea may be provoking changes in the traditional family experience. The object of this qualitative study was to explore the contextual factors causing conflicts between mothers-in-law and their daughters-in-law in multicultural families. Six mother and daughter in-law dyads from rural areas of South Korea were recruited and interviewed. We found that the mothers-in-law and daughters-in-law had had different motives for the marriage at first. Five major themes emerged from the analysis of the dyadic interviews: the conflicts of the participants were embedded in the alternative family formation, in financial strains and the power structure, barriers in communication, cultural insensitivity and conflicts between value systems, as well as in role conflicts due to differing role expectations and hegemony. In conclusion, the authors of this study suggest that increasing cultural sensitivity and communication skills in immigrant daughter-in-law an Korean mother-in-law relationships will be crucial for a healthy in-law relationship. The need for the availability of Multicultural Family Centers' services in the community was highlighted. In order for mothers-in-law and daughters-in-law to form positive relationships, it is important to facilitate a variety of easily accessible educational programs in the community focusing on fostering the mother-in-law's understanding of the daughter-in-law's perspective.

• Korea journal of population studies
• /
• v.8 no.2
• /
• pp.93-99
• /
• 1985

There have been numerous studies in Korea and other countries of which the major hypotheses are identifying and dearibing the conditions under which the value of children has been formed. The present study proposes to view the formation of the value of children as a correlate of family's consumption-saving and work4eisure behavior pattern. The objectives of the proposed study are to identify the socio-economic and demographic factors determining the family's consumption-saving and work-leisure behavior pattern and to analyse the relationship between the value of children and this behavior pattern. The conceptual framwork of the analysis is that an individual family's socio-economic and demographic factors influence and shape the consumption-saving and work-leisure behaviors and these behaviors in turn influence and reflect the correlates and proximate determinants of the family'sfertility. In this paper, regression model is used to analyse the hypothesized relationship among the various variables. The regression methods used are first and second stage multiple regressions. In addition, MONOVA has been used to show the interactions. Data used are collected from the government publicactions. The major findings from this study are as follows: As the living Standard improves, n individual family's consumption of necessities and its working hours decline, while savings and leisure activities increase. The phenomena result in the fertility reduction as can be seen in the more developed conntries. Child-bearing and rearing activities are found to be the important component to determine the condumption-saving and work-leisure activies. The married women's labor participation, and the investment in education and health are also found to be the factors reducing fertility rate.

• Molecules and Cells
• /
• v.38 no.1
• /
• pp.75-80
• /
• 2015

Osteoclasts are unique cells responsible for the resorption of bone matrix. MicroRNAs (miRNAs) are involved in the regulation of a wide range of physiological processes. Here, we examined the role of miR-26a in RANKL-induced osteoclastogenesis. The expression of miR-26a was upregulated by RANKL at the late stage of osteoclastogenesis. Ectopic expression of an miR-26a mimic in osteoclast precursor cells attenuated osteoclast formation, actin-ring formation, and bone resorption by suppressing the expression of connective tissue growth factor/CCN family 2 (CTGF/CCN2), which can promote osteoclast formation via upregulation of dendritic cell-specific transmembrane protein (DC-STAMP). On the other hand, overexpression of miR-26a inhibitor enhanced RANKL-induced osteoclast formation and function as well as CTGF expression. In addition, the inhibitory effect of miR-26a on osteoclast formation and function was prevented by treatment with recombinant CTGF. Collectively, our results suggest that miR-26a modulates osteoclast formation and function through the regulation of CTGF.