• 대한한방내과학회지
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• 제13권1호
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• pp.1-20
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• 1992

The study was carried out to investigate the effect of Kwandongwhasan extract and its constituent herbs onthe contractile force of isolated guineapig trachealis muscle and to elucidate its mechanism. The results of this study were as follows; 1. Kwandongwhasan significantly inhibited the contractile response of isolated guinea pig trachealis muscle by histamine. 2. Kwandongwhasan significantly inhibited the contractile response of isolated guinea pig trachealis muscle by acetylcholine. 3. Kwandongwhasan significantly inhibited the contractile response of isolated guinea pig trachealis muscle by 5-hydrooxytryptamine. 4. Kwandongwhasan significantly inhibited the contractile response of isolated guinea pig trachealis muscle by prostaglandin $F2\;{\alpha}$ 5. Herba Ephedrae (麻黃), Semen Armeniacae(杏仁), Cortex Mormi(紫白皮), and Flos Farfarae (款冬花), extract significantly inhibited the contractile response of isolated guinea pig trachealis muscle by histamine, acetylcholine, 5-hydroxytryptamine and prostaglandin $F2\;{\alpha}$. 6. Radix Glycyrrhdzae(甘草) extract significantly inhibited the contractile response of isolated guinea pig trachealis muscle by prostaglandia $F2\;{\alpha}$. 7. Rhizoma Anemarrhenae(知母) extract significantly inhibited the contractile response of isolated guinea pig trachealis muscle by histamine. 8. Bulbus Fritillariae(貝母) and Tuber Pinelliae(半夏) extract did not inhibit the significantly inhibited the contractile response of isolated guinea pig trachealis muscle.

• Journal of applied mathematics & informatics
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• 제28권3_4호
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• pp.753-762
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• 2010

Let K be a nonempty closed convex subset of a real Hilbert space H. Let T : K $\rightarrow$ K be a nonexpansive mapping with a nonempty fixed point set Fix(T). Let f : K $\rightarrow$ K be a contraction mapping. Let {$\alpha_n$} and {$\beta_n$} be sequences in (0, 1) such that $\lim_{x{\rightarrow}0}{\alpha}_n=0$, (0.1) $\sum_{n=0}^{\infty}\;{\alpha}_n=+{\infty}$, (0.2) 0 < a ${\leq}\;{\beta}_n\;{\leq}$ b < 1 for all $n\;{\geq}\;0$. (0.3) Then it is proved that the modified Krasnoselski-Mann iterative sequence {$x_n$} given by {$x_0\;{\in}\;K$, $y_n\;=\;{\alpha}_{n}f(x_n)+(1-\alpha_n)x_n$, $n\;{\geq}\;0$, $x_{n+1}=(1-{\beta}_n)y_n+{\beta}_nTy_n$, $n\;{\geq}\;0$, (0.4) converges strongly to a point p $\in$ Fix(T} which satisfies the variational inequality

$\leq$ 0, z $\in$ Fix(T). (0.5) This result improves and extends the corresponding results of Yao et al[Y.Yao, H. Zhou, Y. C. Liou, Strong convergence of a modified Krasnoselski-Mann iterative algorithm for non-expansive mappings, J Appl Math Com-put (2009)29:383-389.

• 한국응용과학기술학회지
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• 제24권1호
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• pp.61-66
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• 2007

X-ray diffraction studies have been made to investigate the effects of binding of ADP, ADP+Vi, ADP+AIF4, $ADP+BeF_3$ on the structure of glycerinated rabbit skeletal muscle in the rigor state. Although these phosphate analogs are known to bind actively cycling myosin heads, it is not clear whether they can bind to the attached heads in the rigor muscle. We have found that these analogs can bind to the myosin heads attached to actin filaments in the rigor state. The present results indicate that (1) bound myosin heads altered their conformation in the proximal end toward the plane perpendicular to the fiber axis when MgADP bound to them, and (2) myosin heads were dissociated substantially (up to 50%) from actin filaments but still remained in the vicinity of actin filaments when MgADP and metallofluorides (AIF4 and BeF3) or vanadate bound to them. We detected new conformations of myosin heads attached to actin filaments when they had MgADP or ADP.Pi analogs. We report here these findings on the effects of MgADP and MgADP+phosphate analogs to the rigor crossbridges.

• 대한수의학회지
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• 제34권3호
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• pp.493-500
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• 1994

The purpose of this study was to investigate the effects of neurotransmitters and the source of $Ca^{2+}$ in the effects of neurotransmitters on the motility of pig oviductal isthmic smooth muscle. The motility of the isolated smooth muscle was recorded by using physiological recording system. The results were summarized as follows; Acetylcholine, norepinephrine, histamine and prostaglandin $F_{2{\alpha}}(PGF_{2{\alpha}})$ caused the contraction and the contractile responses were increased in a dose-dependent manner from the concentration of $10^{-7}$ to $10^{-4}M$. The maximum contractility of acetylcholine, norepinephrine, histamine and $PGF_{2{\alpha}}$ was 65.99, 28.66, 83.99 and 47.33% of 100 mM K contraction, respectively. The contractile response induced by acetylcholine$(10^{-6}M)$ was completely blocked by the pretreatment with cholinergic receptor blocker, atropine$(10^{-6}M)$, the contractile response induced by norepinephrine$(10^{-5}M)$ was blocked by the pretreatment with ${\alpha}$-adrenergic receptor blocker, phentolamine$(10^{-6}M)$ but was not blocked and rather increased by the pretreatment with ${\beta}$-adrenergic receptor blocker. propranolol$(10^{-6}M)$, the contractile response induced by histamine$(10^{-6}M)$ was completely blocked by the pretreatment with $H_1$-histaminergic receptor blocker, pyrilamine$(10^{-6}M)$ but was increased by the pretreatment with $H_2$-histaminergic receptor blocker, cimetidine$(10^{-6}M)$. The contractile response induced by acetylcholine$(10^{-6}M)$, norepinephrine$(10^{-5}M)$ and histamine$(10^{-6}M)$ was weakly contracted response in $Ca^{2+}$-free medium, but the contractile response induced by $PGF_{2{\alpha}}(10^{-6}M)$ was disappeared. The contractile response induced by acetylcholine$(10^{-6}M)$, norepinephrine$(10^{-5}M)$ and histamine$(10^{-6}M)$ was powerfully depressed by the pretreatment with $Ca^{2+}$-channel blocker, verapamil$(10^{-5}M)$ but the contractile response induced by $PGF_{2{\alpha}}(10^{-6}M)$ was completely inhibited.

• Journal of applied mathematics & informatics
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• 제28권1_2호
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• pp.13-30
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• 2010

Let C be a nonempty closed convex subset of a real Hilbert space H. Consider the following iterative algorithm given by $x_0\;{\in}\;C$ arbitrarily chosen, $x_{n+1}\;=\;{\alpha}_n{\gamma}f(W_nx_n)+{\beta}_nx_n+((1-{\beta}_n)I-{\alpha}_nA)W_nP_C(I-s_nB)x_n$, ${\forall}_n\;{\geq}\;0$, where $\gamma$ > 0, B : C $\rightarrow$ H is a $\beta$-inverse-strongly monotone mapping, f is a contraction of H into itself with a coefficient $\alpha$ (0 < $\alpha$ < 1), $P_C$ is a projection of H onto C, A is a strongly positive linear bounded operator on H and $W_n$ is the W-mapping generated by a finite family of nonexpansive mappings $T_1$, $T_2$, ${\ldots}$, $T_N$ and {$\lambda_{n,1}$}, {$\lambda_{n,2}$}, ${\ldots}$, {$\lambda_{n,N}$}. Nonexpansivity of each $T_i$ ensures the nonexpansivity of $W_n$. We prove that the sequence {$x_n$} generated by the above iterative algorithm converges strongly to a common fixed point $q\;{\in}\;F$ := $\bigcap^N_{i=1}F(T_i)\;\bigcap\;VI(C,\;B)$ which solves the variational inequality $\langle({\gamma}f\;-\;A)q,\;p\;-\;q{\rangle}\;{\leq}\;0$ for all $p\;{\in}\;F$. Using this result, we consider the problem of finding a common fixed point of a finite family of nonexpansive mappings and a strictly pseudocontractive mapping and the problem of finding a common element of the set of common fixed points of a finite family of nonexpansive mappings and the set of zeros of an inverse-strongly monotone mapping. The results obtained in this paper extend and improve the several recent results in this area.

• 한국인터넷방송통신학회논문지
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• 제23권1호
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• pp.157-162
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• 2023

본 논문은 NP-완전으로 알려진 3-SAT 문제에 대해 O(nm)의 다항시간 알고리즘을 제안하였다. 여기서 n은 3-SAT 수식 f에 포함된 문자수이며, m은 모든 문자의 총 발생 빈도수이다. 제안된 알고리즘은 우선순위롤 정하여 문자의 진리 값을 결정하였다. 하나의 절에 포함된 최소 문자의 수가 1개(k=1)인 문자, k≥2 이고 진리 값이 '0' 또는 '1'만 존재하는 문자, 발생 빈도수가 최소인 문자 우선순위로 진리 값을 결정하였다. 진리 값이 결정된 문자의 r인 절을 삭제하고, 남아 있는 절에서 해당 문자를 삭제하는 방법으로 식을 축소시킨다. 이 과정을 문자 수 l회를 수행하면 주어진 f의 충족 가능 여부를 결정할 수 있다. 이 방법을 적용한 결과 주어진 식 f의 충족 가능 여부를 판단할 수 있었으며, 모든 문자의 진리 값도 결정할 수 있었다. 제안된 알고리즘을 다양한 문제들에 적용한 결과 모든 문제들에서 충족가능 여부를 정확히 결정할 수 있었다. 결국, 제안된 알고리즘은 모든 SAT 문제를 선형시간으로 풀 수 있는 일반화된 알고리즘으로 확장 가능하며, 오랜 숙원이던 P vs. NP 문제를 풀 수 있는 기반을 제공하였다.

• 한국환경생태학회지
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• 제29권6호
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• pp.858-864
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• 2015

문둥이박쥐(Eptesicus serotinus)의 생후 발성발달 특징을 파악하기 위하여 임신한 암컷 3개체로부터 총 4개체의 새끼 박쥐를 확보하여 발성변화를 분석하였다. 녹음 및 분석은 생후 1일부터 40일까지 수행하였으며, 펄스 지속시간(PD), 펄스 간격(PI), 최고 주파수(PF), 시작 주파수($F_{MAX}$), 종료 주파수($F_{MIN}$), 대역폭(BW)에 대하여 측정하였다. 새끼 박쥐는 생후 초기에 가장 다양한 패턴의 음성을 발산하였으며, 연령이 증가함에 따라서 점차 어미와 유사해졌다. PD와 PI는 연령이 증가할수록 감소하였으며, 반면 PF, $F_{MAX}$, $F_{MIN}$, BW는 증가하였다. PF, $F_{MAX}$, $F_{MIN}$, BW는 생후 10일에서 20일 사이에 가장 큰 변화가 확인되었으며, PD는 생후 30일에서 40일 사이에 가장 큰 변화가 확인되었다. 따라서 진동수의 발성과 관련이 있는 발성근육의 수축 능력은 생후 20일경 가장 발달하게 되며, 발성시간과 관련된 발성근육의 이완 능력은 생후 30일에서 40일 사이에 가장 발달하는 것으로 판단된다. 본 연구에 이용된 새끼 개체들은 생후 40일차에도 비행이 확인되지 않았으나 발성음은 어미와 유사하게 나타났다. 따라서 이러한 결과는 새끼 박쥐의 발성 발달은 비행행동 또는 비행과 관련된 근육의 발달을 필수적으로 동반하는 것은 아니라는 것을 보여주는 결과라 판단된다.

• 대한소아치과학회지
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• 제32권2호
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• pp.312-320
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• 2005

이 연구의 목적은 LED 광중합기(Elipar Freelight $2^{(R)}$, 3M-ESPE, USA)의 조사 mode에 따른 복합레진($Supreme^{(R)}$, Filtek $Flow^{(R)}$, 3M-ESPE, USA)의 수축응력과 미세경도를 평가하는 것이다. 수축응력을 측정하기 위해 스트레인 게이지가 사용되었다. 표본은 조사 mode와 충전방법에 따라 6개의 군으로 나누어졌다. A군 : Filtek $Flow^{(R)}$ 이장, $Supreme^{(R)}$ 충전, 10초 광중합, B군 : Filtek $Flow^{(R)}$ 이장 $Supreme^{(R)}$ 충전, 15초 광중합, C군 : Filtek $Flow^{(R)}$ 이장, $Supreme^{(R)}$ 충전, 15초 soft start 광중합, D군 : $Supreme^{(R)}$ 충전, 10초 광중합, E군 : $Supreme^{(R)}$ 충전, 15초 광중합, F군 : $Supreme^{(R)}$ 충전, 15초 soft start광중합. 스트레인 게이지를 아크릴릭 링에 부착하고 strainmeter에 연결한 후 광중합하고 10분 동안 1초 간격으로 측정하고 기록하였다. 24시간 후에 각각 표본의 미세경도를 측정하였다. 결과는 ANOVA와 Tukey test를 이용해 통계학적으로 분석하였다. 결과는 다음과 같았다. 1. Soft start curing 했을 때 수축응력이 낮았다(p<0.05). Flowable resin을 이장한 군에서는 효과가 없었다. 2. 10초간 조사한 군은 15초간 조사한 군에 비해 수축응력이 적었다(p<0.05). 3. 미세경도 측정결과 상면과 하면에서 각 군 간에 차이는 없었다(p>0.05). 하지만, 하면의 미세경도가 상면에 비해 80%에 이르지 못했다.

• Nuclear Medicine and Molecular Imaging
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• 제41권3호
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• pp.263-264
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• 2007

Splenic metastasis from colon carcinoma are rare and usually occur in the presence of disseminated visceral metastasis. The liver is the most common site of metastatic spread from colon cancer. Several hypotheses have attempted to explain the low incidence of splenic metastasis. It should be difficult for colorectal cancer cells to reach the spleen through the portal venous system, in which the blood flow is usually from the spleen to the liver. Reticuloendothelial system or rhythmic contraction of the spleen may squeeze out the tumor in the spleen. The absence of afferent lymphatic to the spleen, phagocytic activity and humoral anticancer substances are considered to be other reason for low incidence of splenic metastasis. We report the case of $^{18}F-FDG$ PET/CT finding in a 70-year-old woman who develop isolated splenic metastasis of sigmoid colon cancer.

• 대한한방내과학회지
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• 제13권1호
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• pp.70-79
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• 1992

This study was carried out to investigate the effect of Yeemosan extract on the contractile force of the isolated guinea pig trachea smooth muscle and elucidate its mechanism. The results were obtained as follows: 1. The contractile response of the trachea smooth muscle of isolated guinea pig to acetylcholine was significantly inhibited by Yeemosan. 2. The contractile response of the trachea smooth muscle of isolated guinea pig pretreated propranolol was significantly inhibited by Yeemosan. 3. Effects of Yeemosan extract on the contractile response of the isolated guineapig trachea smooth muscle pretreated methylene blue was not significant. 4. The contractile response of the trachea smooth muscle of isolated guinea pig to prostaglandin $F2{\alpha)$ was significantly inhibited by Yeemosan. 5. Effects of prostaglandin $F2{\alpha)$ on the contractile response of the isolated guinea pig trachea smooth muscle pretreated Yeemosan was not significant. According to the above results. it was suggested that the contractile response mechanism of the guinea pig trachea smooth muscle to Yeemosan was related to sympathetic nervous system receptor and other mechanism should have further study.