• Title/Summary/Keyword: expanded method

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Privacy model for DTC genetic testing using fully homomorphic encryption (동형암호를 활용한 DTC유전자검사 프라이버시모델)

  • Hye-hyeon Jin;Chae-ry Kang;Seung-hyeon Lee;Gee-hee Yun;Kyoung-jin Kim
    • Convergence Security Journal
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    • v.24 no.2
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    • pp.133-140
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    • 2024
  • The spread of Direct-to-Consumer (DTC) genetic testing, where users request tests directly, has been increasing. With growing demand, certification systems have been implemented to grant testing qualifications to non-medical institutions, and the scope of tests has been expanded. However, unlike cases in less regulated foreign countries, disease-related tests are still excluded from the domestic regulations. The existing de-identification method does not adequately ensure the uniqueness and familial sharing of genomic information, limiting its practical utility. Therefore, this study proposes the application of fully homomorphic encryption in the analysis process to guarantee the usefulness of genomic information while minimizing the risk of leakage. Additionally, to safeguard the individual's right to self-determination, a privacy preservation model based on Opt-out is suggested. This aims to balance genomic information protection with maintainability of usability, ensuring the availability of information in line with the user's preferences.

Design, simulation and experimental analysis of fiber-reinforced silicone actuators

  • Sina Esmalipour;Masoud Ajri;Mehrdad Ekhtiari
    • Structural Engineering and Mechanics
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    • v.91 no.2
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    • pp.211-225
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    • 2024
  • Soft bending actuators have gained significant interest in robotic applications due to their compliance and lightweight nature. Their compliance allows for safer and more natural interactions with humans or other objects, reducing the risk of injury or damage. However, the nonlinear behaviour of soft actuators presents challenges in accurately predicting their bending motion and force exertion. In this research, a new comprehensive study has been conducted by employing a developed 3D finite element model (FEM) to investigate the effect of geometrical and material parameters on the bending behaviour of a soft pneumatic actuator reinforced with Kevlar fibres. A series of experiments are designed to validate the FE model, and the FE model investigates the improvement of actuator performance. The material used for fabricating the actuator is RTV-2 silicone rubber. In this study, the Cauchy stress was expanded for hyperelastic models and the best model to express the stress-strain behaviour based on ASTM D412 Type C tensile test for this material has been obtained. The results show that the greatest bending angle was achieved for the semi-elliptical actuator made of RTV2 material with a pitch of 1.5 mm and second layer thickness of 1 mm. In comparison, the maximum response force was obtained for the semi-elliptical actuator made of RTV2 material with a pitch of 6 mm and a second layer thickness of 2 mm. Additionally, this research opens up new possibilities for development of safer and more efficient robotic systems that can interact seamlessly with humans and their environment.

High-Speed Signal Processing Using GPU for Space Surveillance Radar (GPU를 이용한 우주감시레이다 신호처리 고속화 방안)

  • In-cheol Cho;Sung-hoon Cho;Ji-hoon An;Hyun-wook Moon;Sung-hwan Sohn;Taehee Jeong;Sangho Lim
    • Journal of Advanced Navigation Technology
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    • v.28 no.5
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    • pp.616-622
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    • 2024
  • Recently, each country is competitively investing huge amounts of money in space development, and space risks such as tens of thousands of satellites, spy satellites, and space debris are increasing. Although there are several assets for monitoring space, interest is growing in the detection of space objects using radar, which is useful for constant alert and wide-area surveillance. While the existing radar system was operated to detect aircraft, ships, and missiles within hundreds of kilometers, radar to detect space objects must be expanded to thousands of kilometers. In this case, the size of data that impairs signal processing increases, which can lead to a decrease in radar detection performance. In this paper, we present a method of speeding up signal processing using GPU when detecting space objects, which are long-distance targets, and the results of comparing performance compared to existing CPUs.

Clinical Study on the Successful Pregnancy and Delivery after Transfer of Human Blastocysts Cryopreserved by Vitrification (인간 포배란의 유리화동결 융해 후 임신 및 분만에 관한 연구)

  • Choi, Dong-Hee;Chung, Hyung-Min;Chung, Mi-Kyung;Lee, Sook-Hwan;Nam, Yoon-Seung;Park, Chan;Kwak, In-Pyung;Yoon, Tae-Ki
    • Clinical and Experimental Reproductive Medicine
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    • v.27 no.4
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    • pp.367-372
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    • 2000
  • Objective: This study was performed to evaluate whether vitrification method could be used for the cryopreservation of human blastocysts derived from IVF program. Methods: Surplus embryos were obtained from consented IVF patients. Controlled ovarian hyperstimulation was done with midluteal GnRH agonist, gonadotropin and hCG. After oocyte retrieval and insemination, fresh embryo transfer was done at $4{\sim}8$ cell stage. The surplus embryos after ET were cultured in blastocyst medium up to 6 days after oocyte retrieval. Obtained blastocysts were cryopreserved with our vitrification method. Blastocysts were exposed to 1.5 Methylene glycol (EG) in phosphate buffered saline (PBS) for 2.5 minutes, followed by 5.5 M EG plus 1 M sucrose for 20 seconds. Then 1 to 3 blastocysts were mounted on electron microscope (EM) grid and the grid was plunged into liquid nitrogen for storage. For thawing, blastocyst-containing EM grids were sequentially transferred in 1.0 M, 0.5 M, 0.25 M, 0.125 M and 0 M sucrose solution at the intervals of2.5 minutes. And blastocysts were cultured for about 6 hours and only re-expanded blastocysts were transferred to uterus of the patients on 4 to 5 days after ovulation in natural cycle or on 18 to 19 day of artificial cycle. Results: From Oct. 1998 to Jul. 1999, 34 patients were agreed to participate in this study. The mean age and duration of infertility of the patients were 31.6 years and 4.1 years, respectively. Among 34 cycles. replacements could be done in 20 cycles (58.8%). A total 93 blastocysts were thawed and 48 (51.6%) of them survived. Thirty-eight blastocysts, mean 1.9 embryos per patient, were transferred, resulting in 5 clinical pregnancies which consisted of 1 triplet, 2 sets of twins and 2 singleton pregnancies. The pregnancy rate per transfer was 25% and implantation rate was 23.6%. Five patients delivered 7 healthy babies including 2 sets of twins at term. Conclusion: Successful pregnancies and deliveries were established after transfer of vitrified human blastocysts. Vitrification using ethylene glycol as cryoprotectant and electron microscope grid is a rapid and simple method that can be effectively applied for the cryopreservation of human blastocysts.

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Embryo Gender Ratio and Developmental Potential after Biopsy of In Vivo and In Vitro Produced Hanwoo Embryos

  • Cho, Sang-Rae;Choe, Chang-Young;Son, Jun-Kyu;Cho, In-Cheol;Yoo, Jae-Gyu;Kim, Hyung-Jong;Ko, Yeong-Gyu;Kim, Nam-Young;Han, Sang-Hyun;Park, Yong-Sang;Ko, Moon-Suck
    • Reproductive and Developmental Biology
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    • v.36 no.4
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    • pp.269-273
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    • 2012
  • The present study was to assess the in vitro viability and sexing rate of bovine embryos. Blastocysts were harvested on day 7~9 day after insemination(in vitro and in vivo), and the sex of the embryos was examined using the LAMP method. Embryo cell biopsy was carried out in a $80{\mu}l$ drop $Ca^{2+}$, $Mg^{2+}$ free D-PBS and, biopsied embryos viability were evaluated after more 12 h culture in IVMD culture medium. The formation of recovered embryo to expanded and hatching stages had ensued in higher of sexed embryo in vivo than in vitro (100% vs. 89%, p<0.05), and in vitro, the rates of degeneration after sexing were significantly (p<0.05) higher in vitro than in vivo(11% vs. 0.0%). The rates of the predicted sex were female 61% vs. 56%, and male 39% vs. 44% in vivo and in vitro, respectively. The rates of survival following different biopsy methods were seen between punching and bisection method in vivo and in vitro (100% vs. 89% and 100% vs, 78% respectively). Biopsy method by punching was significantly (p<0.05) higher than bisection between produced embryos in vivo and in vitro. The present data indicate that with microblade after punching for embryo sexing results in high incidence of survivability on development after embryo biopsy. It is also suggested that LAMP-based embryo sexing suitable for field applications.

A Study on the pH Reduction of Controlled Low Strength Material with Coal Ash (석탄회를 활용한 CLSM의 pH 저감에 관한 연구)

  • Kim, Youngil;Jee, Sunghyun;Chun, Byungsik
    • Journal of the Korean GEO-environmental Society
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    • v.11 no.9
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    • pp.39-45
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    • 2010
  • Controlled low strength material(CLSM) is produced by mixing portland cement, fine aggregates, water and chemical admixtures. Sand is the most commonly used as the fine aggregates in the conventional CLSM. It is getting more and more difficult to obtain sand in Korea so it is required that the alternative materials be developed as the replacement of sand. Since the engineering characteristics of coal ash are similar to the sand, it becomes necessary to examine the application of the coal ash as the alternative material for CLSM and as the environment-friendly material. When the results meet the optimum pH level that plants can live, it can be expanded the scale of application of the study on the plant as the important field. This study was subjected to present the method to reduce the pH range of CLSM to a suitable condition that plants can survive. To verify this method, the care of neutralization was conducted by immersing the specimen to Ammonium monohydrogen phosphate. Before curing and neutralization, the maximum pH of developmental CLSM is approximately 11. However, the pH value of developmental CLSM has under 9.5 after peaceful curing and neutralization management.

Effect of Salt on Crystal Growth of Plate-like Alumina Particles by Molten-salt Method (Molten-salt 방법에 의해 합성되는 판상형 알루미나 분말의 입성장 거동에 미치는 Salt의 영향)

  • Kim, Bo Yeon;Lee, Yoon Joo;Shin, Dong-geun;Kim, Soo Ryong;Kwon, Woo Teck;Kim, Younghee;Choi, Duck Kyun
    • Korean Chemical Engineering Research
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    • v.53 no.5
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    • pp.603-608
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    • 2015
  • Alumina powder have been expanded its application in industry and required to control its morphology such as powder size and aspect ratio of single particle. It can be synthesized by molten - salt method which is possible to obtain various shapes of ceramic particles by controlling the growth direction because each crystal face has different growth rate. In this study, various combinations of salts such as NaCl, $Na_2SO_4$, $Na_3PO_4$ and their mixture were used for control the growth of plate like alumina particle from the initial stage of synthesis because salt having different ionic strength can control the growth direction of ceramic particle under its melting condition around $800{\sim}900^{\circ}C$, and growth behavior of plate-like alumina particle with different reaction conditions such as temperature and concentration on the crystal size and shape was studied.

Log Management System of Web Server Based on Blockchain in Cloud Environment (클라우드 환경에서 블록체인 기반의 웹서버 로그 관리 시스템)

  • Son, Yong-Bum;Kim, Young-Hak
    • KIPS Transactions on Computer and Communication Systems
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    • v.9 no.7
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    • pp.143-148
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    • 2020
  • Recently, web services have been expanded to various areas with the evolution of cloud environment. Whenever a user accesses a web service, the user's log information is stored in the web server. This log information is used as data to analyze the user's web service tendencies and is also used as important data to track the user's system access when a security problem in the system occurs. Currently, most web servers manage user log information in a centralized manner. When user log information is managed in a centralized manner, it is simple in the side of operation, but has a disadvantage of being very vulnerable to external malicious attacks. In the case of centralized management, user log information stored in the web server can be arbitrarily manipulated by external attacks, and in severe cases, the manipulated information can be leaked. In this case, it not only decreases the trust of the web service, but also makes it difficult to trace the source and cause of the attack on the web server. In order to solve these problems, this paper proposes a new method of managing user log information in a cloud environment by applying blockchain technology as an alternative to the existing centralized log management method. The proposed method can manage log information safely from external attacks because user log information is distributed and stored in blockchain on a private network with cloud environment.

A Study on Methodology of Scenario-Based Interface Design - with an focus on Scenario Collection and Verification method through Web Survey (시나리오 기반 인터페이스 디자인 방법론에 관한 연구 - 웹 서베이를 통한 시나리오 수집과 검증 방법을 중심으로)

  • 김현정
    • Archives of design research
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    • v.16 no.2
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    • pp.395-404
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    • 2003
  • As scenario-based design is expanded to various fields of design, it is introduced to HCI(Human Computer Interaction) in order to figure out user information & tasks. However, scenario based design methods that is focused on collecting scenarios regarding users'needs, is mainly utilized conceptual design stage for system itself. There is a gap between users'need scenarios to interface design of HCI system. In this study, web survey is suggested as scenario based interface design method in order to connect scenario collecting to task specification and to menu structure design of home-network controller. The degree of users'need for specified tasks was verified to various kinds of users through web survey and it decideddepth and order of menu structure. Tasks also was categorized to situation mode and users can make their own menu structure by selecting menu contents or even mode itself, because degrees of need for specified task situation were varied by lifestyle of user group. Finally, it is found that web survey method can be applied to collect and database various scenarios of. various users when a questionnaire is well designed for collection.

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The Method of Exposure Determination for Digital Infrared Photography in Forensic Field (법과학 분야에서 디지털 적외선 사진을 위한 노출 결정 방법)

  • Kim, Sang-Ki;Kim, Yoo-Jin
    • The Journal of the Korea Contents Association
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    • v.14 no.2
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    • pp.181-191
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    • 2014
  • In the past, making IR photography needed somewhat complicated process, so its application fields were limited. However, it has become easy to make IR photography with advanced digital technology, so it is expected that the fields of IR photography and existing limit due to difficult making process will be expanded. Therefore, in this study, it is decided that the need of IR standard chart which allows us to manage exposure and tone of IR photography for scientific purpose will increase. Two methods were used to make IR standard chart. First method is to use aluminum. When aluminum has oxide coating through anodic oxidation, it has high durability, corrosion resistance and heat resistance. Also, IR reflectance of aluminum can be controlled in some degree depending on the thickness of oxide coating. Second method is to use pigments. Yellow 10P150 pigment is used for the brightest patch. This pigment is appropriate in this study due to high heat resistance and IR reflectance. Carbon black is used for the darkest patch. Carbon black absorbs much IR, and its color is not faded by any source of light. IR reflectance is adjusted elaborately by mixing two pigments. Finally, 6 patches are selected with consideration for actual IR reflectance of patches. As a result, IR reflectance of random subjects can be known approximately and IR photographs can have appropriate contrast with the IR standard chart.