• 제목/요약/키워드: exciting potential

검색결과 74건 처리시간 0.023초

수직운동(垂直運動)이 최소(最小)인 부표(浮標)의 불규칙파(不規則波)중 계류상태(繫留狀態)에 대한 동력학적(動力學的) 해석(解析) (Theoretical Study on the Dynamic Response of a Moored Buoy with Minimum Vertical Wave-exciting Force in Irregular Waves)

  • 최항순;김효철;성우제
    • 대한조선학회지
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    • 제21권3호
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    • pp.43-50
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    • 1984
  • A body form, which experiences minimum vertical wave-exciting forces in the vicinity of a prescribed wave frequency in water of finite depth, is obtained by an approximate method. Its configuration has the symmetry with respect to the vertical axis, expressed in terms of exponential functions. By distributing three-dimensional pulsating sources and dipoles on the immersed surface of the body, a velocity potential is determined and subsequently hydrodynamic forces including the 2nd-order time-mean drift forces are calculated. The dynamic behavior of the body moored in irregular waves is investigated numerically by using central difference method. Hereby irregular wave trains are simulated with examining its repeatability by comparing the resulting spectrum with original one. Numerical results indicated that the body form obtained from the present analysis possesses in general a favorable hydrodynamic characteristics in comparison with a spherical buoy and that the maximum excursion of the body can be significantly reduced by setting pre-tension of an appropriate amount in the mooring cable.

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PSMA Inhibitors for Nuclear Imaging and Radiotherapy of Prostate Cancer

  • Sajid Mushtaq;Tugsuu Uyanga;Park Ji Ae;Jung Young Kim
    • 대한방사성의약품학회지
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    • 제9권1호
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    • pp.23-33
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    • 2023
  • Prostate cancer ranks as the world's second most frequently diagnosed cancer among men, and is responsible for the fifth highest number of cancer-related deaths in this population. The development of effective diagnostic and therapeutic approaches for prostate cancer remains a major challenge in the field of oncology. Over the past few years, the prostate-specific membrane antigen (PSMA) has raised as a hopeful tracer for the diagnosis and treatment of prostate cancer.Various radioisotopes, such as 131I, 99mTc, 68Ga, and 177Lu, have been used to label PSMA analogues, with varying degrees of success. Among these, 68Ga-PSMA-11 and 177Lu-PSMA-617 have emerged as the most promising radioligands for clinical use. Recently, researchers have been exploring the use of other radioisotopes, such as 211At, 89Zr, 64/67Cu, and 203/212Pb, for the labeling of PSMA-targeted radioligands. These radioisotopes have unique properties that may offer advantages over existing radioligands, such as longer half-lives, higher specific activities, and different emission profiles. Efforts are currently underway to develop these radiopharmaceuticals and make them more widely available for clinical use. These exciting developments highlight the potential of PSMA-targeted radioligands for the diagnosis and treatment of prostate cancer, and provided significant implications for the management of this disease in the future. The current study aims to provide a comprehensive summary of the latest research and clinical applications of radiolabeled PSMA inhibitors for diagnoses and therapy of prostate cancer, emphasizing the exciting developments in the field and their potential impact on clinical practice.

축대칭 부표의 규칙파중 운동특성에 대한 연구 (A Stuty on the Dynamic Response of an Axisymmetric Buoy in Regular Waves)

  • 홍기용;김효철;최항순
    • 대한조선학회지
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    • 제23권3호
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    • pp.1-9
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    • 1986
  • Herein the dynamic response of an axisymmetric buoy to regular wave is studied within linear potential theory. The buoy has a particular geometry so that it should experience minimum wave-exiting force on the vertical direction at a precribed wave number in water of finite depth. Invoking the Green's theorem a velocity potential is generated by distributing pulsating sources and doublets on the immersed surface of the buoy at its mean position. Hydrodynamic forces and moments are obtained approximately by summation of the products of linear pressure and directional mesh area over the immersed surface. Model tests are carried out to measure the wave-exciting forces, hydrodynamic forces and motion responses. The experimental results in general agree fairly well with the numerical ones. From the analytical and experimental works it is found that the pitching motion and its coupling effect affect significantly the motion characteristics of the freely-floating axisymmetric buoy in regular waves.

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생체의 자극 전도속도에 관한 연구 (A Study on the Propogation Velocity of Biological Action Potential)

  • 최규식;권용찬
    • 한국항행학회논문지
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    • 제14권6호
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    • pp.1002-1009
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    • 2010
  • 본 논문에서는 축삭의 전도 현상을 분석하기 위해서 축삭을 전기전도 모델로 만든 후 여기에 키르히호프의 전류법칙과 전압법칙을 적용한 등가회로를 구성하였다. 축삭의 미세거리 변화에 의한 전위의 거동을 분석하기 위하여 축삭의 각종 파라미터를 구하였다. 검토결과에 의하면 무수신경인 경우 직경을 미지수로 하여 인체의 파라미터를 이용하면 그 속도는 직경의 제곱근에 비례한다. 한편 유수신경인 경우는 그 속도가 직경에 직접적으로 비례한다. 미엘린이 없는 막과는 달리 미엘린껍질의 전도는 전압과 무관하므로 이러한 막 양단의 Hodgkin-Huxley 형 전도모델이 매우 정교하지는 않다.

하이브리드 기법을 이용한 고정된 해양구조물에 작용하는 파랑하중에 관한 수치 시뮬레이션 (Numerical Simulation of Wave Forces acting on Fixed Offshore Structures Using Hybrid Scheme)

  • 남보우;홍사영;김용환
    • 한국해양공학회지
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    • 제24권6호
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    • pp.16-22
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    • 2010
  • In this paper, the diffraction problems for fixed offshore structures are solved using a hybrid scheme. In this hybrid scheme, potential-based solutions and the Navier-Stokes-based finite volume method (FVM) with a volume-of-fluid (VOF) method are combined. We introduce a buffer zone for efficient wave-making and damping. In this buffer zone, the near field solution from FVM-VOF is gradually changed to Stokes' 2nd order wave solutions. Three different models, including the truncated cylinder, sphere, and wigleyIII model, are numerically investigated in regular waves with a wave steepness of 1/30. The efficiency and accuracy of the hybrid scheme are numerically validated from results using different domain sizes and buffer zones. The wave exciting forces from the FVM-VOF simulations are compared with experiments and potential-based solutions from the higher-order boundary element method (HOBEM). This comparison shows good agreement between the hybrid scheme and potential-based solutions.

임계치 이하의 자극에 대한 생체의 반응 연구 (A Study on the Bio-response to the Underthreshold Stimulation)

  • 최규식
    • 한국항행학회논문지
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    • 제14권3호
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    • pp.439-445
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    • 2010
  • 인체의 신호정보전달은 각 세포 단위에서 발생되는 활동전위에 의하여 이루어지고 있다. 이러한 활동전위는 세포막을 통한 이온들의 움직임에 의해서 발생, 전달되고 있으며, 궁극적으로는 전기적인 신호의 개념으로 설명될 수 있다. 즉, 생체에서 발생되는 각종 감각을 비롯한 정보의 전달이 전기적인 현상으로 이루어진다는 것이 그간의 수많은 연구를 통하여 밝혀지고 있다. 그런데 그동안에는 이러한 신경전달관계가 정성적으로 기술되고 분석되었다. 따라서 본 논문에서는 이러한 관계를 정량적으로 분석하기 위해서 알고리즘을 세우고 이미 제시된 데이터를 이용하여 이를 구현하고자 하였다. 단, 이미 언급한 것처럼 본 논문에서는 외부 자극이 신경계가 발화를 필요로 하는 임계치 이상이 아니라 그 이하인 경우를 분석하였다. 이는 전기회로의 과도현상과 매우 유사하며, 이와의 유사성에 근거하여 분석하였다. 본 논문에서 제시하여 연구 및 분석한 결과를 나타내어 앞으로의 연구 주제의 기초가 되도록 하였다.

모바일게임 이용 충족이론을 기반으로 한 모바일 게이머 유형 분석에 관한 연구 (A Study on Gamers Segmentation based upon Uses and Gratifications of Mobile games)

  • 한광현;김태웅
    • 한국경영과학회:학술대회논문집
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    • 한국경영과학회 2005년도 추계학술대회 및 정기총회
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    • pp.133-164
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    • 2005
  • Mobile games have emerged as the most innovative entertainment technology, adding new revenue streams, taking advantage of the potential of wireless applications and service offerings. Mobile games, like any other types of computer game, offer a unique value for users in providing an exciting digital experience in virtual worlds. Players can become empowered through the development of new characters and strategies within games to achieve rewarding successes against the computers and other players. The overall trend for mobile games is towards bigger, more colorful, more involving and exciting contents, which will build upon the developing capabilities of mobile phones and networks in order to bring new styles, concepts and experiences of game play to the users. In this paper, we attempt to investigate the demographic factors which play critical roles in determining the level of playing times; classify mobile gamers based on their motives for playing games; and empirically test differences in their demographic factors and mobile game usage. Statistical results show that significant differences in playing times exist, depending upon their age, gender, mobile device, mobile phone usage, mobile game experiences, and preferred games genres. Applying Factor analysis, we have identified Escape, Social interaction, Challenge and Competition, Fantasy, Diversion and Relaxation, Ease of Accessibility as key motivators for playing mobile games. Additional cluster analysis shows that the categorization of gamers, according to their usage habits and the key motivators for playing, can be made as follows: M-gamers, Multi-gamers and Communication-focused gamers. Further correlation of these grouping with socio-economic data shows the significant differences in gaming habits and patterns of mobile phone use.

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Wave Force Analysis of the Three Vertical Cylinders in Water Waves

  • Kim, Nam-Hyeong;Cao, Tan Ngoc Than
    • 한국항해항만학회지
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    • 제32권7호
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    • pp.543-552
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    • 2008
  • The diffraction of waves by three bottom fixed vertical circular cylinders is investigated by using the boundary element method. This method has been successfully applied to the isolated vertical circular cylinder and now is used to study the interaction between waves and multiple vertical cylinders. In this paper, a numerical analysis by the boundary element method is developed by the linear potential theory. The numerical analysis by the boundary element method is based on Green's second theorem and introduced to an integral equation for the fluid velocity potential around the vertical circular cylinders. To verify this method, the results obtained in present study are compared with the results computed by the multiple scattering method. The results of the comparisons show strong agreement. Also in this paper, several numerical examples are given to illustrate the effects of various parameters on the wave exciting force such are the separation distance, the wave number and the incident wave angle. This numerical computation method might be used broadly for the design of various offshore structures to be constructed in the future.

Biological Control Strategy of Uzi Fly in Sericulture

  • Singh, R.N.;Saratchandra, Beera
    • International Journal of Industrial Entomology and Biomaterials
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    • 제6권2호
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    • pp.125-132
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    • 2003
  • Uzi fly (Exorista bombycis Louis) is one of the major larval endo-parasitoid of silkworm (Bombyx mori). It causes extensive damage to sericulture industry. The application of synthetic organic pesticides has tremendous impact on minimizing pest population but their overuse and frequent misuse and high sensitivity towards the silkworms, has forced the entomologists to search for alternatives to chemical control, which is safe to silkworm, environment and farm workers. Biological control continues to offer exciting possibilities for the control of fly pest population. It is environmentally safe alternative to chemical control and offering a long-term protection. Several potential hymenopteran parasitoids have been screened. Among successful natural enemies, Nesolynx thymus, Trichomalopsis apanteloctena, Trichopria sp., Brachymeria lasus, Pediobius sp., Spalangia sp., Spilomicrus karnatakensis and Dhirhinus sp. are important. It is essential to predict accurately the efficacy of these natural enemies in a new habitat prior to its introduction. The important desirable attributes of these potential parasitoids viz., host searching capacity, specificity, power of increase and fitness and adaptability of the parasitoid in new environment has been recorded. Results of the host parasitoid interaction indicate that the aging of the host function as a factor that influence the host finding efficiency of the parasitoid. It is highly scored with 15-20 hrs old pupa of the host. However, aging of the parasitoid does not significantly affect it. The sex ratio is female biased which is advantageous from biological control point of view, Biological suppression methods involving conservation and utilization of natural enemies have been discussed in detail.

픽법에 의한 생체 내의 농도 확산 분석 (Analysis of density diffusion analysis by Fick's laws in the human body)

  • 최규식
    • 한국항행학회논문지
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    • 제16권4호
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    • pp.657-664
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    • 2012
  • 용질분자를 용매를 통하여 전달시키는 기법중의 하나는 확산에 의한 것이다. 이러한 기전은 각개 용질분자의 열운동에 의한 것이다. 유체는 정지해 있는 상태로서 용질 전달의 핵심기전은 농도차에 의하여 결정된다. 인체 내에서 각종 하전 이온을 포함한 입자나 분자들은 체내의 농도차에 의해서 또는 외부 전계에 의해서 영향을 받아 고농도에서 저농도쪽으로 확산되어간다. 이러한 현상은 픽이 제안한 확산에 관한 제1법칙과 제2법칙에 의하여 정량적으로 전개할 수 있다. 본 논문에서는 체내의 물질이 확산되는 과정을 픽의 법칙을 이용하여 해석하고 그것을 실례를 통하여 구현하였다. 각 시간별 공간상의 확산현상에서 확산계수가 클 때는 시간이 경과함에 따라 발생지점의 농도는 현저히 낮아지고 그 농도가 주위로 급속히 확산되어감을 알 수 있었다. 그러나 어느 정도의 시간이 경과되면 그 농도의 감소는 매우 약해진다.