• Proceedings of the KACD Conference
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• 2003.11a
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• pp.606-606
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• 2003

There have been many studies that have evaluated success and failure of endodontic treatment (Nair, Sjogren), but there is remarkably limited information concerning the specific microorganisms that are involved in the teeth with treatment failure. Microorganisms that survive root canal treatment to cause a persistent infection must possess specific characteristics to avoid the host defense. These can be broadly classified as; 1. Sequestration：A physical barrier between the microbe and the host. 2. Cellular evasion：Microorganisms avoid leukocyte dependent antibacterial mechanisms. 3. Humoral evasion：Extracellular bacteria avoid the hosts antibodies and complement.(omitted)

• Health Policy and Management
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• v.14 no.2
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• pp.78-98
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• 2004

The purpose of this study was to categorize the contribution evasion and develop the expected models for contribution arrears in National Health Care System. The modified logistic regression model in non-payments was used as logistic regression model based on the statistical method. By using this model, we arranged non-payment types and typical branches those are appeared by statistical technique. First fact, sex and age branches those are able to take a part in economy had effect mostly. Also they had difference in non-payment probability by existence of their incomes and property. Especially people who didn't have their own house and car were appeared in high non-payment probability, disease and reduction characteristic(rare diseases, reduction of seniors, handicaps, numbers of medical treatments) didn't effect much in probability. The reason for some characteristic of non-payment which is higher than the correct threshold value of Logistic Regression Model (a suggested model for predicting non-payment)'s distribution of probability was mostly moral hazard. Living difficulty was the bigger reason for non-payment, but moral slackening was the bigger reason for non-payment. But it is careless to decide that moral hazard is just the reason, there is a necessity to examine on the side of sociology based in family. By the reason, the member's non-payment reason can be classified by economy, population, and psychology, but there was a comprehension that losing of work desire could be one reason. So we analyzed informations for composition of family of members. In conclusion, we grasped that family conflict makes non-payment and conversion of member in the National Basic Livelihood Protection System difficult.

• Molecules and Cells
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• v.39 no.11
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• pp.777-782
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• 2016

The innate immune system has evolved to detect and destroy invading pathogens before they can establish systemic infection. To successfully eradicate pathogens, including viruses, host innate immunity is activated through diverse pattern recognition receptors (PRRs) which detect conserved viral signatures and trigger the production of type I interferon (IFN) and pro-inflammatory cytokines to mediate viral clearance. Viral persistence requires that viruses co-opt cellular pathways and activities for their benefit. In particular, due to the potent antiviral activities of IFN and cytokines, viruses have developed various strategies to meticulously modulate intracellular innate immune sensing mechanisms to facilitate efficient viral replication and persistence. In this review, we highlight recent advances in the study of viral immune evasion strategies with a specific focus on how Kaposi's sarcoma-associated herpesvirus (KSHV) effectively targets host PRR signaling pathways.

• IEIE Transactions on Smart Processing and Computing
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• v.3 no.4
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• pp.226-233
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• 2014

This paper presents an external light evasion method that rectifies the problem of misrecognition due to external lighting. The fundamental concept underlying the proposed method involves recognition of the differences between two images and elimination of the desynchronized external light by synchronizing the image sensor and inner light source of the optical touch screen. A range of artificial indoor light sources and natural sunlight are assessed. The proposed system synchronizes with a Vertical Synchronization (VSYNC) signal and the light source drive signal of the image sensor. Therefore, it can display synchronized light of the acquired image through the image sensor and remove external light that is not from the light source. A subtraction operation is used to find the differences and the absolute value of the result is utilized; hence, the order is irrelevant. The resulting image, which displays only a touched blob on the touchscreen, was created after image processing for coordination recognition and was then supplied to a coordination extraction algorithm.

• Journal of the Korea Institute of Military Science and Technology
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• v.12 no.1
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• pp.8-17
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• 2009

This paper proposes robust ship wake search method in the target evasion environment. Moving surface ships generate a long trailing wake in the rear of a surface ship. Wake homing torpedo sensing this wake can detect the surface target and engage it automatically. In wake homing torpedo, wake search method is important element to maximize effectiveness of wake homing torpedo. This paper proposes one-side, two-side and centering mode according to passing wake boundary scenarios. Also, wake deflection angle is deduced by using the principle of deflection angle of acoustic torpedo. The representative experimental results using monte-carlo simulation demonstrate that the searching method using one-side mode is superior to two-side and centering mode in the target evasion environment.

• Journal of the Korea Institute of Military Science and Technology
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• v.23 no.4
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• pp.399-406
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• 2020

In this paper, we propose a time-varying proportional navigation guidance law that determines the proportional navigation gain in real-time according to the operating situation. When intercepting a target, an unidentified evasion strategy causes a loss of optimality. To compensate for this problem, proper proportional navigation gain is derived at every time step by solving an optimal control problem with the inferred evader's strategy. Recently, deep reinforcement learning algorithms are introduced to deal with complex optimal control problem efficiently. We adapt the actor-critic method to build a proportional navigation gain network and the network is trained by the Proximal Policy Optimization(PPO) algorithm to learn an evasion strategy of the target. Numerical experiments show the effectiveness and optimality of the proposed method.

• The KIPS Transactions:PartB
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• v.15B no.3
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• pp.253-258
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• 2008

Recently, game players want new game requiring more various tactics and strategies in the complex environment beyond simple and repetitive play. Various artificial intelligence techniques have been suggested to make the game characters learn within this environment, and the recent researches include the neural network and the genetic algorithm. The Genetic programming(GP) has been used in this study for learning strategy of the agent in the pursuit-evasion problem which is used widely in the game theories. The suggested GP algorithm is faster than the existing algorithm such as neural network, it can be understood instinctively, and it has high adaptability since the evolving chromosomes can be transformed to the reasoning rules.

• Molecules and Cells
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• v.44 no.6
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• pp.408-421
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• 2021

The outbreak of coronavirus disease 2019 (COVID-19) has not only affected human health but also diverted the focus of research and derailed the world economy over the past year. Recently, vaccination against COVID-19 has begun, but further studies on effective therapeutic agents are still needed. The severity of COVID-19 is attributable to several factors such as the dysfunctional host immune response manifested by uncontrolled viral replication, type I interferon suppression, and release of impaired cytokines by the infected resident and recruited cells. Due to the evolving pathophysiology and direct involvement of the host immune system in COVID-19, the use of immune-modulating drugs is still challenging. For the use of immune-modulating drugs in severe COVID-19, it is important to balance the fight between the aggravated immune system and suppression of immune defense against the virus that causes secondary infection. In addition, the interplaying events that occur during virus-host interactions, such as activation of the host immune system, immune evasion mechanism of the virus, and manifestation of different stages of COVID-19, are disjunctive and require thorough streamlining. This review provides an update on the immunotherapeutic interventions implemented to combat COVID-19 along with the understanding of molecular aspects of the immune evasion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which may provide opportunities to develop more effective and promising therapeutics.

• Proceedings of the Microbiological Society of Korea Conference
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• 2004.05a
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• pp.95-96
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• 2004

• International Commerce and Information Review
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• v.11 no.4
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• pp.263-287
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• 2009

This paper aims at examining whether the current Korean customs punishment system is appropriate and reasonable for eliminating customs offenses, such as smuggling, and explores ways to improve the penal provisions of customs law. The current multiple fine system, governed by the penalty for evasion of customs duty, penalty for abatement and exemption by fraud or unfair practices and penalty for drawback by fraud or unfair practices, clearly violates a sense of responsibility and the constitutional principle of no excess punishment. Therefore it should be changed to a fixed fine system and confiscate and collect in addition the items with customs evasion and exemption by fraud or unfair practices.