• Title/Summary/Keyword: enhancing effect

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Study on biopolymer delivery system and effect of wound healing with polysaccharide extracted from Agaricus blazei Murill

  • Kim, Min-Kyoung;Lee, Hye-Young;Hong, Eock-Kee
    • 한국생물공학회:학술대회논문집
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    • 2005.10a
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    • pp.816-820
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    • 2005
  • Polysaccharide-based dressings have increasingly become viable alternatives to somewhat less biocompatible and often problematic cotton or viscose gauzes traditionally used for wound dressings. Polysaccharide which is particularly abundunt in Agaricus blazei Murill is known as the bioactive materials. Polysaccharide extracted from Agaricus blazei Murill enhances the recovery of the damaged epidermal tissue and the production of epithelial cell growth factors which are necessary to heal the burn and wound on the epidermal tissue. In this study, the biopolymer delivery system of polysaccharide extracted from Agaricus blazei Murill into epidermal tissue was elucidated using the skin permeating enhancer in vitro. The enhancing effects of various penetration enhancers and some other enhancers on the permeation of ${\beta}-glucan$ were evaluated using Franz diffusion cell. Permeation of polysaccharide in nomal and burn skin was compared. Polysaccharide was studied for the burn and wound healing activity in the epidermal tissue on rats.

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Influence of defective sites in Pt/C catalysts on the anode of direct methanol fuel cell and their role in CO poisoning: a first-principles study

  • Kwon, Soonchul;Lee, Seung Geol
    • Carbon letters
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    • v.16 no.3
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    • pp.198-202
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    • 2015
  • Carbon-supported Pt catalyst systems containing defect adsorption sites on the anode of direct methanol fuel cells were investigated, to elucidate the mechanisms of H2 dissociation and carbon monoxide (CO) poisoning. Density functional theory calculations were carried out to determine the effect of defect sites located neighboring to or distant from the Pt catalyst on H2 and CO adsorption properties, based on electronic properties such as adsorption energy and electronic band gap. Interestingly, the presence of neighboring defect sites led to a reduction of H2 dissociation and CO poisoning due to atomic Pt filling the defect sites. At distant sites, H2 dissociation was active on Pt, but CO filled the defect sites to form carbon π-π bonds, thus enhancing the oxidation of the carbon surface. It should be noted that defect sites can cause CO poisoning, thereby deactivating the anode gradually.

Effect of Interlayers on the Bending Strength of Silicon Nitride/Staineless Steel Joints (중간재가 질화규소/스테인레스 스틸 접합체의 굽힘강도에 미치는 영향)

  • 박상환;최영화;김태우
    • Journal of the Korean Ceramic Society
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    • v.33 no.3
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    • pp.251-258
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    • 1996
  • The reactions between an active metal brazing alloy and interlayers together with the effects of interlayer type on the interfacial microstructure change were investiaged for silicon nitride/stainless steel joint. The bending strengths were measured for joints with Mo, Cu, Ni interlayer type of different thicknesses. It was found that the interlayer with a low yield strength value is effective to improve the bending strength of the Si3N4/stainless steel joint. The maximum joint strength obtained at room temperature for a laminated Cu/Mo interlayer was about 460 MPa. The combined use of Mo and thin Cu layer was found to be effective in enhancing the bending strength for the Si3N4/S.S.316 joint.

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The Effect of the Job Satisfaction and Job Training of Family Restaurant Employees on Service Quality (패밀리 레스토랑 근무자의 직무 만족과 직무 교육이 서비스 품질에 미치는 영향에 관한 연구)

  • An, Kwang-Yeol
    • Culinary science and hospitality research
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    • v.14 no.4
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    • pp.306-316
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    • 2008
  • The purpose of this study is to identify how and job satisfaction and job training affect service quality and to offer strategic tools for enhancing competitiveness of the food service business industry. To fulfill this purpose, this study utilized a factor analysis, frequence test, a reliability analysis and a covariance structure analysis. The results of the analyses show that one dimension such as "job training" influenced service quality. This means that restaurants should put more focus on job training to improve service quality for customers.

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Lipopolysaccharide (LPS)-Induced Autophagy Is Responsible for Enhanced Osteoclastogenesis

  • Sul, Ok-Joo;Park, Hyun-Jung;Son, Ho-Jung;Choi, Hye-Seon
    • Molecules and Cells
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    • v.40 no.11
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    • pp.880-887
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    • 2017
  • We hypothesized that inflammation affects number and activity of osteoclasts (OCs) via enhancing autophagy. Lipopolysaccharide (LPS) induced autophagy, osteoclastogenesis, and cytoplasmic reactive oxygen species (ROS) in bone marrow-derived macrophages that were pre-stimulated with receptor activator of nuclear $factor-{\kappa}B$ ligand. An autophagy inhibitor, 3-methyladenine (3-MA) decreased LPS-induced OC formation and bone resorption, indicating that autophagy is responsible for increasing number and activity of OCs upon LPS stimulus. Knockdown of autophagy-related protein 7 attenuated the effect of LPS on OC-specific genes, supporting a role of LPS as an autophagy inducer in OC. Removal of ROS decreased LPS-induced OC formation as well as autophagy. However, 3-MA did not affect LPS-induced ROS levels, suggesting that ROS act upstream of phosphatidylinositol-4,5-bisphosphate 3-kinase in LPS-induced autophagy. Our results suggest the possible use of autophagy inhibitors targeting OCs to reduce inflammatory bone loss.

A Study of Beat Transfer Characteristics of Large Scale Vortex Flow Mixing Vane of Nuclear Fuel Rod Bundle (핵연료집합체에서의 대형이차와류 혼합날개의 열전달 특성에 관한 연구)

  • An, Jeong-Soo;Choi, Young-Don
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.30 no.1 s.244
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    • pp.24-31
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    • 2006
  • Mixing vanes have been installed in the space grid of nuclear fuel rod bundle to improve turbulent heat transfer. Split mixing vanes induce the vortex flow in the cooling water to swirl in sub-channel of fuel assembly. But, The swirling flow decays rapidly so that the heat transfer enhancing effect limited to short length after the mixing vane. In thi present study, the large scale vortex flow(LSVF) is generated by rearranging the mixing vanes to the coordinated directions. This LSVF mixing vanes generate the most strong secondary flow vortices which maintain about 35 $D_H$ after the spacer grid. The streamwise vorticity generated by LSVF sustain two times more than that split mixing vane. Heat transfer in the rod bundle occurs greatly at the same direction to cross flow, and maximum temperature at the surface of bundle drops about 1.5K

Task Oriented Approach of Hemiparetic Patients (편마비환자의 과제지향 접근법)

  • Kim Seong-hak;Park Rae-joon
    • The Journal of Korean Physical Therapy
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    • v.16 no.2
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    • pp.54-62
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    • 2004
  • The propose of this study was to evaluate the effect of body weight support treadmill training on the patients with chronic stroke. Body weight support(BWS) treadmill training has recently been shown to be effective for gait training following stroke, and few researchers have measured the usefulness of this intervention in enhancing function, and there are reports in which BWS overground ambulation was studied. This study were 1) to report the feasibility and patient tolerance for using a BWS system for treadmill ambulation, 2) to measure the function of patients with chronic stroke prior to and following BWS treadmill and overground ambulation training, and 3) to describe a protocol used for patient treatment progression using BWS treadmill training.

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EFFECT OF NITROGEN POSITION ON EXCITED STATE PROPERTIES OF 1-(9- ANTHRYL )-2-(n-QUINOLINYL)ETHENES

  • Shin, Eun-Ju
    • Journal of Photoscience
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    • v.6 no.2
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    • pp.61-65
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    • 1999
  • The fluorescence properties and photoisomerization behavior of 1-(9-anthryl)-2-(n-quinolinyl)ethene (n-AQE, n=2-4) have been investigated in various solvents. t-3-AQE is strongly fluorescent, but does not accomplish photoisomerization, similar to parent hydrocarbon compound, t-1-(9-anthryl)-2-phenylethene (t-9-APE) or t-1-(9-anthryl)-2-(1-naphthyl)ethene (t-1-ANE). Fluorescence and photoisomerization oft-2-AQE and t-4-AQE are strongly affected by solvent polarity. Dependence of fluorescence quantum yield on the solvent polarity is moderate for t-2-AQE and large for t-4-AQE. In nonpolar solvent (in n-hexane), they exhibit relatively strong fluorescence, but do not isomerize to cis isomer on irradiation, even if inefficient isomerization is observed for t-4-AQE. However, as solvent polarity increases, their fluorescences become weak with efficient photoisomerization to corresponding cis isomer. Intramolecular charge-transfer excited state is presumed to contribute to photoisomerization. The S$_1$ decay parameters were found to be solvent-dependent due to the charge-transfer character of lowest S$_1$ state. In polar solvents, the activation barrier to twisting is reduced enhancing the isomerization of r-2-AQE and t-4-AQE in the singlet manifold.

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Free and Glycosidically Bound Volatile Components in Tobacco Leaves(Nicotiana tabacum L.) (잎담배중 유리 및 Glycoside형태로 존재하는 휘발성 향기성분)

  • 김영회;나도영;김옥찬;서철원;김용태
    • Journal of the Korean Society of Tobacco Science
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    • v.14 no.1
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    • pp.79-86
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    • 1992
  • Free and glycosidically bound volatiles from three green tobacco leaves(NC 82, KF 109 and Br-21) were separated by nonionic resin Amberlite XAD-2 adsorption column chromatography and election by selective solvents. Aglycones from the glycosidically bound fractions were released by enzymatic hydrolysis with almond B-glucosidase. A total of 20 components identified from free and glycosidically bound fractions, the major components were benzaldehyde, benzyl alcohol, 2-phenylethyl alcohol, 3-oxo- -ionol, 3-hydroxy-B-ionone, 3-oxo-7, 8-dihydro-n-ionol and scopoletin. Six Cl.B norisoprenoids identified in this study, which have been described to possess a characteristic tobacco aroma-enhancing effect, were not presented in free forms but rather bound glycosidic forms.

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Flotation Characteristics of Activated Sludge by Micro-bubbles (미세 기포에 의한 활성슬러지의 부상특성)

  • Kim, Seong-Jin;Kang, Byoung-Jun;Park, Sang-Wook;Lee, Jae-Wook;Jung, Heung-Joe;Kwak, Dong-Heui
    • Journal of Korean Society of Water and Wastewater
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    • v.20 no.4
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    • pp.501-507
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    • 2006
  • Dissolved air flotation (DAF) has been well known for the gravity separation process. The solids to be separated are transferred from the water body to the water surface using micro-air bubbles. DAF has also been used for enhancing solids-liquid separation of industrial and municipal wastewater by adding a its unit parallel to a sedimentation unit to reduce the hydraulic loading in the sedimentation clarifier. This study was to investigate flotation characteristics of activated sludge by the recent DAF technique without chemical agents. In addition, the effect on temperature in flotation of activated sludge and the thickening degree of activated sludge were studied.