• 제목/요약/키워드: eIF5B

검색결과 201건 처리시간 0.03초

Quantitative and Qualitative Assessment of Blow Down Wastewater from Yeosu Industrial Complex (여수석유화학산단 산업폐수 재이용을 위한 블로우 다운 (Blow Down)수 발생현황 조사)

  • Kwon, Tae-Ouk;Moon, Il-Shik
    • Journal of Korean Society on Water Environment
    • /
    • 제21권3호
    • /
    • pp.289-296
    • /
    • 2005
  • Purpose of this research is to quantitatively and qualitatively investigate the blow down wastewater produced from Yeosu Industrial Complex. Approximately, 38,325,000 tons/year of wastewater is produced, processed and finally discharged. Six representative companies, namely, A, B, C, D, E, F were chosen for this study. Each company produce over 5,000 tons/day of wastewater. In total, 6,844 tons/day of blow down water is produced from these six companies, put together. However, companies A and C produce about 24% and 37% of blow down water, respectively. It was found that the blow down water had favorable qualities, except for its high conductivity, ranging from 230 to $1,700{\mu}s/cm$. It was evident that, this water can be suitable for reuse, for industrial purposes, if a suitable treatment, for example, RO membrane process is adopted to remove high conductivity.

Evaluation of Meat from Native Chickens: Analysis of Biochemical Components, Fatty Acids, Antioxidant Dipeptides, and Microstructure at Two Slaughter Ages

  • Ali, Mahabbat;Lee, Seong-Yun;Park, Ji-Young;Nam, Ki-Chang
    • Food Science of Animal Resources
    • /
    • 제41권5호
    • /
    • pp.788-801
    • /
    • 2021
  • This study examined biochemical components, fatty acids, antioxidant dipeptides, and muscle fiber density of breast and thigh muscles from Korean new native chicken strains (A and B) at two slaughter ages, compared with white semi-broiler (W) or broilers. The pH values were different by chicken breed. The new native strains had the lowest fat content in the breast at 12 wk (p<0.05). Regardless of the muscles, A and B at 12 wk had higher levels of arachidonic acid (ARA; C20:4), docosahexaenoic acid (DHA; C22:6), and nervonic acid (C24:1) than broilers (p<0.05). A similar result was observed for the polyunsaturated fatty acids (PUFAs) and polyunsaturated and saturated fatty acids ratio (P/S) content in the breast. Irrespective of the muscles, A and B enriched with omega-3 fatty acids had a lower ω-6/ω-3 PUFA ratio than broilers (p<0.05) at 12 wk. Of the antioxidant di-peptides, the anserine contents were highest in A and B than in the W or broilers (p<0.05), regardless of the muscles and slaughter ages. Furthermore, the breast meat from A and B contained a higher muscle fiber density for both slaughter ages than the W and broilers (p<0.05). Based on these findings, even if the commercial birds (broilers or W) are raised under the similar environmental conditions as A and B, the new native chicken strains have distinct meat quality attributes, particularly higher ARA and DHA levels, lower ω-6/ω-3 PUFA ratio, and higher anserine contents.

Nimodipine as a Potential Pharmacological Tool for Characterizing R-Type Calcium Currents

  • Oh, Seog-Bae
    • The Korean Journal of Physiology and Pharmacology
    • /
    • 제5권6호
    • /
    • pp.511-519
    • /
    • 2001
  • Nimopidine, one of dihydropyridine derivatives, has been widely used to pharmacologically identify L-type Ca currents. In this study, it was tested if nimodipine is a selective blocker for L-type Ca currents in sensory neurons and heterologous system. In mouse dorsal root ganglion neurons (DRG), low concentrations of nimodipine $(<10\;{\mu}M),$ mainly targeting L-type Ca currents, blocked high-voltage-activated calcium channel currents by ${\sim}38%.$ Interestingly, high concentrations of nimodipine $(>10\;{\mu}M)$ further reduced the 'residual' currents in DRG neurons from ${\alpha}_{1E}$ knock-out mice, after blocking L-, N- and P/Q-type Ca currents with $10\;{\mu}M$ nimodipine, $1\;{\mu}M\;{\omega}-conotoxin$ GVIA and 200 nM ${\omega-agatoxin$ IVA, indicating inhibitory effects of nimodipine on R-type Ca currents. Nimodipine $(>10\;{\mu}M)$ also produced the inhibition of both low-voltage-activated calcium channel currents in DRG neurons and ${\alpha}_{1B}\;and\;{\alpha}_{1E}$ subunit based Ca channel currents in heterologous system. These results suggest that higher nimodipine $(>10\;{\mu}M)$ is not necessarily selective for L-type Ca currents. While care should be taken in using nimodipine for pharmacologically defining L-type Ca currents from native macroscopic Ca currents, nimodipine $(>10\;{\mu}M)$ could be a useful pharmacological tool for characterizing R-type Ca currents when combined with toxins blocking other types of Ca channels.

  • PDF

Performance Analysis of 1.8GHz CDMA 1x Reverse Link including Tower Mount LNA (Tower Mount LNA 장착에 따른 CDMA PCS 기지국의 역방향 성능 분석)

  • Park Sang-Hyeon;Choe Yeong-Wan;Yun Yeong-Sang;Jang Jae-Seon
    • 한국정보통신설비학회:학술대회논문집
    • /
    • 한국정보통신설비학회 2003년도 하계학술대회
    • /
    • pp.143-148
    • /
    • 2003
  • In this paper, we focused on the performance of reverse link in 1.8GHz CDMA 1x system including the Tower-Mount LNA in an urban environment. In order to study the benefit of TMLNA, Hata model is used and the effects of multiple cells are considered. Cell coverage extension ratio is proportional to the increased gain of TMLNA in CDMA cell site. However the cell coverage is not extended even if the noise figure of TMLNA is reduced in an urban area. When typical RSSI is between -70dBm and -80dBm, the increased gain and the reduced NF of TMLNA are not impact to the pole capacity of cell site. Namely, the benefit of TMLNA in an urban area is not the problem of capacity but the proble of sensitivity. The results are also shown that reverse link $E_b/N_o$ is improved by minimum 5dB and BER is lower than $10^{-6}$.

  • PDF

An Analysis of the Fashion Brands Followed by a Recall Range (브랜드의 회상 범위에 따른 패션 브랜드 분석)

  • Yu, Ji-Hun
    • The Research Journal of the Costume Culture
    • /
    • 제15권6호
    • /
    • pp.996-1007
    • /
    • 2007
  • This study was focused on recognitive reaction. The purposes of this study was to analyze the fashion brands through correlation analysis between top of mind, recall, recognition, impact index and consumer behavior, and to identify the graveyard brand, niche brand and core brand. 33 questions about 20 fashion brands were asked to 442 males and females from the middle school students to age of 40. Data were analyzed mean, standard deviation, frequency, and correlation by using SPSS 12.0. The results were as follows: 1. Top of mind, recall and recognition affected recognizing the brands and including evoked setting, but it didn't lead the customer to purchase the brand. 2. Although top of the mind and recall are high, the percentage of purchasing the brand is relatively low if a consumer doesn't own the brand. 3. Brands 'B', 'L', 'PF', 'D' and 'BM' were represented as niche Brands which had high recognition and memory. 4. Brands 'TB', 'I', 'EN', 'ML', 'E' could be Graveyard brands that need special management. 5. Brands with the high impact index were 'A', 'T', 'I', 'C' and 'B'. These brands were recognized as the core brands by consumers.

  • PDF

Fertilizer Effect of Waste Nutrient Solution in Greenhouses for Young Radish Cultivation (열무 재배를 위한 시설하우스 폐양액의 비료 효과)

  • Hong, Youngsin;Moon, Jongpil;Park, Minjung;Son, Jinkwan;Yun, Sungwook
    • Journal of Bio-Environment Control
    • /
    • 제31권4호
    • /
    • pp.460-467
    • /
    • 2022
  • The purpose of this study is to enhance utilization of the waste nutrient solution (WNS) disposed at the hydroponic greenhouse. Several sets of testing were conducted to examine the effects of WNS: (a) a fertilizer effect, (b) soil column leaching, and (c) crop cultivation. The fertilizer effect test was applied in young radish cultivation by examining the growth characteristics of young radish and soil based on inorganic nitrogen according to the soil treatment of the nitrogen fertilizer (NF) and the WNS. The fertilizer effects and crop cultivation test were conducted with five treatments (A-E): A, non-treatment (water); B, 100% of NF; C, 70% of NF + 30% of WNS; D, 50% of NF + 50% of WNS; and E, 30% of NF + 70% of WNS. The soil column leaching test was conducted with three treatments: non-treatment (water), 100% of NF, 50% of WNS + 50% of NF. As a result, the chemical properties of the WNS were pH 6.0, EC 2.4dS·m-1, total phosphorus (T-P) 28mg·L-1, ammonium nitrogen (NH4-N) 5.0mg·L-1, and nitrate nitrogen (NO3-N) 301mg·L-1. The chemical properties of the soil were pH 5.51, EC 0.31dS/m, organic matter 2.08g·kg-1, NO3-N 9.64mg·kg-1, and NH4-N 3.20mg·kg-1. The results of fertilizer effects showed that the ratio of 50% or less of NF and 50% or more of WNS was high in young radish growth. There was no statistically significant difference between the soil chemistry in the C-E treatments where WNS was mixed with NF and the B treatment where only NF was applied. As a result of the soil column leaching test, there was no significant difference in the concentrations of NO3 and NH4 in the treatment of 100% of NF and 50% of NF + 50% of WNS. The study indicates, if the mixed fertilizer of WNS and NF is applied in the soil cultivation of young radish, it will reduce the use of NF and environmental pollution. This also helps reduce production costs on farmers and increase the yield of young radish.

Proposal of a New TNM Classification for Gastric Cancer: Focusing on pN3b and Cytology-Positive (CY1) Disease

  • Kim, Sa-Hong;Lee, Hyuk-Joon;Park, Ji-Hyeon;Choi, Jong-Ho;Park, Shin-Hoo;Choe, Hwi-Nyeong;Oh, Seung-Young;Suh, Yun-Suhk;Kong, Seong-Ho;Park, Do-Joong;Yang, Han-Kwang
    • Journal of Gastric Cancer
    • /
    • 제19권3호
    • /
    • pp.329-343
    • /
    • 2019
  • Purpose: Gastric cancer with lymph node metastasis (LNM) more than 15 (N3b) was defined as stage IV until the 6th AJCC system. However, it has been reclassified as a localized disease (stage IIb or III) since the 7th system. The aim of this study is to demonstrate that the survival of N3b is comparable to cytology-only positive (CY1-only) stage IV and to propose a new TNM system interpreting N3b as an eligibility criterion for receiving more intensive chemotherapy regimens. Materials and Methods: 1,430 patients who underwent gastric cancer surgery at Seoul National University Hospital from 2007 to 2012 were retrospectively analyzed. The 5-year survival rate (5YSR) and 3-year recurrence-free survival (RFS) were evaluated according to the 7th and 8th systems, as well as a new categorization based on N-classification; N0-2 (LNM<7), N3a (LNM 7-15), or N3b (LNM>15). Results: The survival of N3b is comparable to that of CY1-only stage IV (log rank test, P=0.671) and is distinct from that of grossly stage IV (log rank test, P<0.001). The survival of the remaining stage IIIc (T4bN3a) was comparable to those of N3b and CY1-only stage IV. Most N3b patients had significantly shorter 3-year RFS and mean RFS than those with IIb-IIIc, as if N3b itself was a higher TNM stage. Conclusions: In terms of survival, T4bN3a, N3b, and CY1-only stage IV were unified as stage IVa, while grossly stage IV was defined as stage IVb. N3b can be regarded as an eligibility criterion for undergoing more intensive chemotherapy regimens.

INTERRELATIONSHIP BETWEEN VIRULENT CLONAL TYPES, SEROTYPES AND LEUKOTOXICITY OF KOREAN STRAINS OF A. ACTINOMYCETEMCOMITANS (한국인 Actinobacillus actinomycetemcomitans 균주의 특이 독성 clone형과 혈청형 및 백혈구독성과의 관계)

  • Ku, Young
    • Journal of Periodontal and Implant Science
    • /
    • 제25권3호
    • /
    • pp.487-496
    • /
    • 1995
  • Previous studies have demonstrated that not all A. actinomycetemcomitans produced significant level of leukotoxic factor and its leukotoxicity have associated with serotype and genetic variation. Our aim was to investigate on the interrelationship between serotype and leukotoxicity of an A. actinomycetemcomitans consisting of 13 clinically well characterized. Korean isolates and to evaluate if particular virulent clonal types of A. actinomycetemcomitans are associated with periodontal disease. For this study, 13 strains of A. actinomycetemcomitans from 6 patients with periodontal disease were isolated and identified by using a selective medium(tryptic soy agar supplemented with 10% serum, $75{\mu}g$ of bacitracin and $5{\mu}g$ of vancomycin per ml) in 10% C02 incubator for 3days with routine Gram staining, colony morphology and biochemical test..For serotyping, antisera were prepared from reference strains of 5 serotypes. (ATCC 29523,Y4, SUNY aB 67, IDH 781, IDH 1705) and then ammonium sulfate precipitation, immunoabsorption and indirect immunofluoroscent procedures were done. For analysis of leukotoxicity, sonic extract of A. actinomycetemcomitans exposed to PMN, and trypan blue was stained for counting the cell viability. Finally Southern blot analyses of genomic DNA digested with the restriction enzyme Tag I was done and the Southern blots were hybridized with the 530bp fragment, termed delta 530, originating from the ltx promoter of strain 652 and deleted from strain JP2. Also ltxA-3.1 and SC2 probe from strain JP2 were hybridized with genomic DNA fragments. Results reveal that strains isolated showed approximately equal proportions of 3 serotypes(b, d, e) and serotype b was not detected. 2 patients harbored 2 different serotypes in the same disease site. The prevalence of leukotoxic strain was 23% and there was no relationship between serotype, leukotoxicity and clinical observations. Especially virulent clonal types of Actinobacillus actinomycetemcomitan (JP2 strain) could not found. Further studies are necessary on the genetic polymorphism of leukotoxin and its relations to clinical status.

  • PDF

Change in Solving Process According to Problem Type - Centered on Reaction toward Linear Equations of Seventh Grade Students - (문제 유형에 따른 풀이과정에서의 변화 - 중학교 1학년 학생들의 일차방정식에 대한 반응을 중심으로 -)

  • Seo, J.J.
    • Communications of Mathematical Education
    • /
    • 제24권2호
    • /
    • pp.445-474
    • /
    • 2010
  • The results of performing first survey after learning linear equation and second survey after 5 months to find out whether there is change in solving process while seventh grade students solve linear equations are as follows. First, as a result of performing McNemar Test in order to find out the correct answer ratio between first survey and second survey, it was shown as $p=.035^a$ in problem x+4=9 and $p=.012^a$ in problem $x+\frac{1}{4}=\frac{2}{3}$ of problem type A while being shown as $p=.012^a$ in problem x+3=8 and $p=.035^a$ in problem 5(x+2)=20 of problem type B. Second, while there were students not making errors in the second survey among students who made errors in the solving process of problem type A and B, students making errors in the second survey among the students who expressed the solving process correctly in the first survey were shown. Third, while there were students expressing the solving process of linear equation correctly for all problems (type A, type B and type C), there were students expressing several problems correctly and unable to do so for several problems. In conclusion, even if a student has expressed the solving process correctly on all problems, it would be difficult to foresee that the student is able to express properly in the solving process when another problem is given. According to the result of analyzing the reaction of students toward three problem types (type A, type B and type C), it is possible to determine whether a certain student is 'able' or 'unable' to express the solving process of linear equation by analyzing the problem solving process.

Cloning of cDNA Encoding Putative Cellular Receptor Interacting with E2 protein of Hepatitis C Virus (C형 간염바이러스 E2 단백질에 결합하는 추정 세포수용체 cDNA의 클로닝)

  • 이성락;백재은;석대현;박세광;최인학
    • Journal of Life Science
    • /
    • 제13권4호
    • /
    • pp.541-550
    • /
    • 2003
  • E2 glycoprotein of hepatitis C virus (HCV) comprises a surface of viral particle together with E1 glycoprotein, and is thought to be involved in the attachment of HCV viral particle to receptor (s) on the permissible cells including hepatocytes, B cells, T cells, and monocytes. We constructed a phage library expressing cellular proteins of hepatocytes on the phage surface, which turned out to be 8.8${\times}$$10^5$ cfu of diversity and carried inserts in 95% of library. We screened both cDNA phage library and 12-mer peptide library to identify the cellular proteins binding to E2 protein. Some intracellular proteins including tensin and membrane band 4.1 which are involved in signal transduction of survival and cytoskeleton organization, were selected from cDNA phage library through several rounds of panning and screening. On the contrary, membrane proteins such as CCR7, CKR-L2, and insulin-like growth factor-1 receptor were identified through screening of peptide library. Phages expressing peptides corresponding to those membrane proteins were bound to E2 protein specifically as determined by neutralization of binding assay. Since it is well known that HCV can infect T cells as well as hepatocytes, we examined to see if E2 protein can bind to CCR7, a member of C-protein coupled receptor family expressed on T cells, using CCR7 transfected tells. Human CCR7 cDNA was cloned into pcDNA3.1(-) vector and transfected into human embryonic kidney cell, 293T, and expressed on the surface of the cell as shown by flow cytometer. Binding assay of E2 protein using CCR7 transfected cells indicated that E2 protein bound to CCR7 by dose-dependent mode, giving rise to the possibility that CCR7 might be a putative cellular receptor for HCV.