• YAKHAK HOEJI
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• v.35 no.5
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• pp.372-378
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• 1991

To increase the stability and bioavailability of Omeprazole(OMP), which is used newly as a proton-pump inhibitor, inclusion complex of OMP with $\beta$-cyclodextrin($\beta$-CD) was prepared by coprecipitation method and its characteristics were ascertained by means of solubility test, DSC, IR, and the accelerated stability analysis. The type of OMP inclusion complex is classified as Bs-type on phase solubility diagram, and the stoichiometric ratio of OMP: $\beta$-CD complex is 1:2 and formation constant is 80.82/mole. The solubility of the complex could be increased remarkably by complexation compare with OMP. Degradation process of both OMP and OMP complex followed apparent first-order kinetics, of which degradation rate constants and activation energies are k$_{25}$=8.1$\times$10$^{-4}$/day, E$_{a}$=22 Kcal/mole (OMP), and k$_{25}$=4.65$\times$10$^{-6}$/day, E$_{a}$=35 Kcal/mole (complex), respectively. These results show the increase of the stability and solubility of OMP markedly, therefore it is believed that the improvement of stabilization for OMP by inclusion complexation might be practically available.

• Information Systems Review
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• v.7 no.1
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• pp.1-20
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• 2005

In this paper we evaluate the Korean e-government portal and linked web sites, based on usability. We pick a set of 18 representative government sites, and consider two approaches of type-I and type-II testing with different questionnaires. We ask users two questions at each site, regarding simple facts. We count a task as successful if the user find the right answer for fact questions. In type-I testing, after users have finished working with a site, we give them a post-test questionnaire asking them to rate the site in 16 different areas, in order to calculate the site rating. In type-II testing, we investigate page design, contents design, and site design of the web sites.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.5 no.1
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• pp.133-142
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• 1992

We analyzed clinical study in 47 patients, who had visited to the Dept. of Otolaryngology, Hospital of Oriental Medicine, Kyung Hee University to treat Otitis media with effesion from March, 1991 to February, 1992. The clinical etiology of O.M.E. was tubal occlusion, acute otitis, and allergy. The clinical symptoms were hearing loss, tinnitus, sneezing, coughing, Chun-I(纏耳), and BEE-Yeon(鼻淵) in the Oriental Medicine. The results were as follows. 1. There were 26 males ($55\%$) and 21 females ($45\%$) in sex. 2. The peak age at onset was 1-4 years old (11Cases). 3. Bilateral effusion was in $62\%$, and unilateral in $38\%$. 4. The etioloigic factors were upper respiratory infection 16 cases, Allergic rhinitis 13 cases, Sinusitis 8 cases, etc. 5. The most common chief complaint was hearing loss ($30\%$). 6. There was no significant difference between blood types in O.M.E., ( A type $30\%,\;B\;type\;25\%,\;AB\;type\;13\%,\;0\;type\;13\%$, Unknown recorded $9\%$ ). 7. $21\%$ patients prefered warm and the others cold 8. As for digestion, good was in 31 cases ($81\%$), and poor 9 cases ($19\%$). 9. Man-Hyung-Ja-San Extract was most used in treatments as $38\%$, O-Ryung-San $35\%$ in descending order. 10. As for treatment period, 14 cases were treated over 12 weeks, 9 cases below 1 week

• Proceedings of the KIEE Conference
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• 1997.07a
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• pp.244-246
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• 1997

This paper is to analyze the Premature Quench characteristics of a rotating magnet type superconducting fluxpump and consider the method of detecting and protecting this premature quench. Practically, there is contact resistance between the fluxpump and the load, namely the S.C. magnet. The thermal increase due to the contact resistance cause the premature quench before the charging current amounts to the critical current of S.C magnet. Therefore, this paper is devoted to solving the heat equation on contact region using cylindrical coordinates and to calculating the rate of thermal increase during the current is pumped up. Doing so, the predictive value of the maximum pumping current is obtained. It has been verified that the results of simulation are coincident with those of experiment. It must be considered essentially to minimize the contact resistance in designing the S.C fluxpump system in order to protect the premature quench and improve the maximum pumping current.

• The Korean Journal of Nuclear Medicine Technology
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• v.27 no.1
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• pp.36-41
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• 2023

Purpose The long-term trend of extrinsic uniformity by type of gamma camera was analyzed, and the factors affecting uniformity were investigated. Based on this, the purpose was to predict the life of the gamma camera, pay attention to factors that affect uniformity, and obtain better quality images. Materials and methods Four of the gamma cameras in operation at a senior general hospital in Seoul were selected and the trend of extrinsic uniformity from the first operation date to the present was analyzed. In order to minimize various factors affecting uniformity, a detailed analysis was conducted by calculating the monthly and annual average of the uniformity values. Results Two Symbia E gamma cameras from SIEMENS, one Symbia Evo Excel gamma camera, and one Symbia Intevo16 gamma camera were selected and analyzed. The uniformity of Symbia E₁ (2012 warehousing) changed unevenly, and the uniformity of Symbia E₂ (2014 warehousing) changed according to the replacement cycle of ⁵⁷Co sheet sources. The uniformity of Symbia Evo Excel (received in 2017) and Symbia Intevo 16 (received in 2017) was constant compared to Symbia E. Conclusion The extrinsic uniformity of the gamma camera gradually increased over time. However, there was a difference in uniformity for each type of gamma camera, and there was a change in uniformity in which the cause could not be accurately identified. In order to improve the quality of the image, it is necessary to periodically check changes in uniformity and minimize factors that affect uniformity.

• Journal of the Korean Society of Clothing and Textiles
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• v.26 no.6
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• pp.923-934
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• 2002

The aim of this study is to suggest a Sizing System which has following points:- 1. In order to satisfy children of diverse figure shapes, we developed sizing system for three different figure type. Figure types are categorized into slim, normal, fat type based on the Rohrer Index. 2. For each figure types, we developed size chart using height bust circumference and hip circumference as basic measurements. The size codes are presented as the height-bust circumference or height-hip circumference. The size interval of height is 5cm for all figure types, such as 120,125,130 ‥‥ we developed a size allocation program, which is helpful when a customer doesn't know exact measurement of some body dimension. If a customer input measurements as much as he/she hows, the program allocates the nearest. At the end of the study, the sizing interaction sites were developed to present the results of the study clear.

• Journal of the Korean Operations Research and Management Science Society
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• v.11 no.1
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• pp.36-43
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• 1986

In this study, the fuzzy programming is extended to handle various types of membership functions by transformation of the complicated fuzzy programming problems into the equivalent crisp linear programming problems with single objective. It is well-known that the fuzzy programming problem with linear membership functions (i.e., ramp type) can be easily transformed into a linear programming problem by introducing one dummy variable to minimize the worst unwanted deviation. However, until recently not many researches have been done to handle various general types of complicated linear membership functions which might be more realistic than ramp-or triangular-type functions. In order to handle these complicated membership functions, the goal dividing concept, which is based on the fuzzy set operation (i. e., intersection and union operations), has been prepared. The linear model obtained using the goal dividing concept is more efficient and single than the previous models [4, 8]. In addition, this result can be easily applied to any nonlinear membership functions by piecewise approximation since the membership function is continuous and monotone increasing or decreasing.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2016.05a
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• pp.162-163
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• 2016

This paper presents a mathematical model for optimizing earthwork allocation plan that minimizes earthwork cost. The model takes into account operational constraints in the real-world earthwork such as material-type (i.e., quality level of material) and quantities excavated from cut-sections, required quality of material and quantities for each embankment layer, top-down cutting and bottom-up filling constraints, and allocation orders. These constraints are successfully handled by assuming the rock-earth material as the three dimensional (3D) blocks. The study is of value to project scheduler because the model identifies the optimal earth allocation plan (i.e., haul direction (cut and fill pairs), quantities of soil, type of material, and order of allocations) expeditiously and is developed as an automated system for usability. It is also relevant to estimator in that it computes more realistic earthworks costs estimation. The economic impact and validity of the mathematical model was confirmed by performing test cases.

• Journal of Advanced Marine Engineering and Technology
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• v.39 no.8
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• pp.843-848
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• 2015

The objective of this study is to observe and optimize a typical ocean environment and reduce wave reflections in the wave flume. In order to generate ocean waves in the wave flume, a combination of a horizontal piston type wave generator and wave absorbers was installed in the channel. Two probes for measuring the wave heights, i.e., wave level gauges, were used to record the continuous variation of the wave surface, the phase difference, and the maximum (crest) and minimum (trough) points of the propagating waves. In order to optimize the shape and size of the propagating waves, several absorption methods were proposed. Apart from an active wave absorption method, we used methods that involved vertical porous plates, horizontal punching plates, and sloping-wall-type wave absorbers. To obtain the best propagating waves, a sloping-wall-type wave absorber was chosen and tested in terms of the constitutive filling materials and the location and shape of the plate. This study also focused on the theoretical prediction of the wave surface, separating them into the incident and reflective components. From the results, it is evident that the wave absorber comprising a hard filling material exhibits a better performance than the absorber comprising a soft material, i.e., the wave absorber can be a strong sink to control the energy of the incoming wave. In addition, larger wave absorbers correspond to lower reflectance because a larger volume can reduce the incoming wave energy. Therefore, at constant absorber conditions, the reflectance of the wave increases as the wave period increases. Finally, the reflectance of the wave was controlled to be less than 0.1 in this study so that the wave flume can be used to simulate an offshore environment.

• BMB Reports
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• v.35 no.4
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• pp.432-436
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• 2002

Pseudomonas sp. S-47 is capable of degrading catechol and 4-chlorocatechol via the meta-cleavage pathway. XyITE products catalyze the dioxygenation of the aromatics. The sylT of the strain S-47 is located just upstream of the xylE gene. XylT of the strain S-47 is located just upstream of the xylE gene. XyIT is typical chloroplast-type ferredoxin, which is characterized by 4 cystein residues that are located at positions 41, 46, 49, and 81. The chloroplast-type ferredoxin of Pseudomonas sp. S-47 exhibited a 98% identity with that of P. putida mt-2(TOL plasmid) in the amino acid sequence, but only about a 40 to 60% identity with the corresponding enzymes from other organisms. We constructed two recombinant plasmids (pRES1 containing xylTE and pRES101 containing xylE without xylT) in order to examine the function of XyIT for the reactivation of the catechol 2,3-dioxygenase (XyIE) that is oxidized with hydrogen peroxide was recovered in the catechol 2,3-dioxygenase (C23O) activity about 4 mimutes after incubation, but the pRES101 showed no recovery. That means that the typical chloroplast-type ferredoxin (XyIT) of Pseudomonas sp. S-47 is involved in the reactivation of the oxidized C23O in the dioxygenolytic cleavage of aromatic compounds.