• Advances in Traditional Medicine
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• v.4 no.2
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• pp.104-111
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• 2004

Sasang Constitutional Medicine is a major branch of Korean Traditional Oriental Medicine. The differences of disease susceptibility to be shown in Sasang constitution may be due to genetic factors. Therefore, we examined interrelationship among cerebral infarction (CI), apolipoprotein E (apoE) gene polymorphism, and Sasang constitutional classification. ApoE is a key protein modulating the highly atherogenic apoB containing lipoproteins and is a candidate gene for the development of coronary artery disease (CAD). The ${\varepsilon}2\;and/or\;{\varepsilon}4$ alleles were the first to be implicated in premature CAD, which resulted in this polymorphism being extensively studied. We investigated the association between apoE genotype and CI by case-control study in a Korean population. We also classified CI patients and control group into groups according to Sasang Constitutional Medicine. 196 CI patients and 379 controls without CI were examined. ApoE genotype was determined by 8% polyacrylamide gel separation after DNA amplification. A significant difference in the apoE genotype distribution was observed in the CI patients compared with that in controls ($X^{2}$=14.920, df=4, P=0.005). Also, the frequency of Taeumin constitution in patients with CI was significantly higher than that in controls (58.0% vs. 36.9%; P<0.001). However, the Taeumin constitution did not enhance the relative risk for CI in the subjects with apoE ${\varepsilon}2\;and/or\;{\varepsilon}4$ alleles. No differences in the apoE genotypes frequencies were observed in the Taeumin compared with that in the other constitutions. In addition, we investigated whether the DD genotype of angiotensin converting enzyme (ACE) gene, a candidate gene for CI, was associated with CI, Taeumin constitution, and apoE polymorphism. As a result, the frequency of Taeumin constitution was significantly higher in CI patients with both apoE ${\varepsilon}3/{\varepsilon}4$ and ACE ID/DD genotypes than in the remaining Sasang constitutions (14.5% vs. 8.3% and 0%) ($X^{2}$=13.521, df=6, P=0.035). In summary, we concluded that the apoE polymorphism is a major risk factor for CI in Koreans and the ACE ID/DD genotype enhanced the relative risk for CI in the subjects with apoE ${\varepsilon}3/{\varepsilon}4$ genotype and Taeumin constitution.

• Proceedings of the Korean Information Science Society Conference
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• 2004.04b
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• pp.499-501
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• 2004

교육의 새로운 방향은 가상 학교나 WBI와 같은 교육적 활용분야로 확대되고 있으나, e-Learning 상에서 이뤄지는 평가의 응시자에 대한 신뢰 확보는 어려운 상황이다. 기존의 인증이란 사용자가 E와 Password를 타인에게 공개하지 않는 한 본인임을 인증하였다. 하지만 온라인상에서 시험 응시자는 본인의 ID와 Password를 타인에게 알려주어 대리시험이 가능하게 함은 물론 시험문제의 공유 또는 다수의 응시자가 한 곳에 모여 문제를 풀어 감으로서 평가에 대한 신뢰도에 의문을 갖지 않을 수 없게 되었다. 이에 인터넷으로 원격조정이 가능한 PC카메라와 얼굴인식 프로그램 그리고 원격제어프로그램을 이용하여 응시자를 인증함으로써 부정행위를 원천적으로 봉쇄하고, 감독자가 언제 어디서나 웹을 통하여 쉽게 감독할 수 있도록 LMS 기능의 보완이 요구된다. 본 논문을 통해서는 채팅기능을 통한 상호 대화가 가능하고 응시 장면을 동영상으로 압축 저장하여 사후 감독이 가능토록 함으로서 e-Learning상에서의 평가 및 학사관리의 공정성 및 신뢰도를 높일 수 있는 방안을 제시하였다.

• The korean journal of orthodontics
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• v.28 no.5 s.70
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• pp.825-838
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• 1998

The purpose of this study was to evaluate the differences of soft tissue profile changes between the growing patients and the adult who had passed the growth peak, in orthodontic treatment with four premolar extractions. The results which was taken by correlating the soft tissue changes with hard tissue changes, lip thickness, molar relationship and arch length discrepancy in both groups was like the followings. 1. Significant hard tissue changes were decrease of VIs, VIi, UlPP, LlMP, HIi and increase of HPog'in adults and decrease of VIs, VIi and increase of VA, VPog'and all the vertical measurements in adolescents. 2. Significant soft tissue changes were decrease of VLs, VLi, and VILS in adults and increase of VSn, VSLS, VLs, VPog' and almost all vertical measurements in adolescents, and ${\Delta}LsE,\;{\Denta}LiE$ in adults and ${\Delta}LsE,\;{\Denta}LiE,\;{\Delta}LiSP\;and\;{\Delta}Mang$ was also significant 3. Correlation coefficient between ${\Delta}VIs\;and\;{\Delta}VLs$ was the greatest in adults and the next was ${\Delta}Ii/{\Delta}Li,\;{\Delta}Ii/{\Delta}ILS,\;{\Delta}ID/{\Delta}Li\;and\;{\Delta}ID/{\Delta}ILS$. In contrast all the vertical and horizontal measurements of hard and soft tissue in adolescents showed statistically significant corerrlation. 4. There were differences in correlation between soft tissue changes and incisor inclination and retraction at both groups, but the lower lip, nasolabial angle and mentolabial angle were commonly less influenced by the hard tissue changes in both groups. 5. The thinner the upper lip was, the more the ${\Delta}LsSP$ was in both groups, and the thinner the lower lip was, the more the ${\Delta}LiE\;and\;{\Denta}LiSP$ was in adolescents. 6. Molar relationship didn't influence the soft tissue profile changes. 7. Arch length discrepancy didn't influence the soft tissue profile changes.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.12C
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• pp.1692-1706
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• 2004

Recently, there are rapid development of information and communication and rapid growth of e-business users. Therefore we try to solve security problem on the internet environment which charges from wire internet to wireless internet or wire/wireless internet. Since the wireless mobile environment is limited, researches such as small size, end-to-end and privacy security are performed by many people. Wireless e-business adopts credit card WPP protocol and AIP protocol proposed by ASPeCT. WAP, one of the protocol used by WPP has weakness of leaking out information from WG which conned wire and wireless communication. certification chain based AIP protocol requires a lot of computation time and user IDs are known to others. We propose a Micro-Payment protocol based on credit card. Our protocol use the encryption techniques of the public key with ID to ensure the secret of transaction in the step of session key generation. IDs are generated using ECC based Weil Paring. We also use the certification with hidden electronic sign to transmit the payment result. The proposed protocol solves the privacy protection and Non-repudiation p개blem. We solve not only the safety and efficiency problem but also independent of specific wireless platform. The protocol requires the certification organization attent the certification process of payment. Therefore, other domain provide also receive an efficient and safe service.

• Honam Mathematical Journal
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• v.32 no.3
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• pp.467-480
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• 2010

There are various papers on finding all the derivations of a non-associative algebra and an anti-symmetrized algebra (see [2], [3], [4], [5], [6], [10], [13], [15], [16]). We and all the derivations of the growing algebra WN($e^{{\pm}x_1x_2x_3}$, 0, 3)[1] with the set of all right annihilators $T_3$ = $\{id,\;\partial_1,\;\partial_2,\;\partial_3\}$ in the paper. The dimension of $Der_{non}$(WN($e^{{\pm}x_1x_2x_3}$, 0, 3)$_{[1]}$) of the algebra WN($e^{{\pm}x_1x_2x_3}$, 0, 3)$_{[1]}$ is one and every derivation of the algebra WN($e^{{\pm}x_1x_2x_3}$, 0, 3)$_{[1]}$ is outer. We show that there is a class P of purely outer algebras in this work.

• Journal of Information Processing Systems
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• v.13 no.4
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• pp.970-986
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• 2017

Certificateless public key cryptography (CL-PKC) is a new benchmark in modern cryptography. It not only simplifies the certificate management problem of PKC, but also avoids the key escrow problem of the identity based cryptosystem (ID-PKC). In this article, we propose a certificateless blind signature protocol which is based on elliptic curve cryptography (CLB-ECC). The scheme is suitable for the wireless communication environment because of smaller parameter size. The proposed scheme is proven to be secure against attacks by two different kinds of adversaries. CLB-ECC is efficient in terms of computation compared to the other existing conventional schemes. CLB-ECC can withstand forgery attack, key only attack, and known message attack. An e-cash framework, which is based on CLB-ECC, has also been proposed. As a result, the proposed CLB-ECC scheme seems to be more effective for applying to real life applications like e-shopping, e-voting, etc., in handheld devices.

• Journal of Dairy Science and Biotechnology
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• v.39 no.3
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• pp.113-120
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• 2021

Although the number of incidences of illness caused by ingestion of the bacterial pathogen Enterobacter sakazakii (Cronobacter spp.) has dramatically declined, there remains a need for a robust isolation method to recover this microbe from powdered infant formula (PIF). The current method described in the FDA's Bacteriological Analytical Manual requires multiple steps, and 3-4+ days for complete analysis of PIF isolated E. sakazakii (Cronobacter spp.). We describe a bacteriological method including a one-step enrichment followed by plating on chromogenic agar for presumptive identification of E. sakazakii (Cronobacter spp.). Suspected colonies are confirmed by either biochemical analyses, or a Real-Time PCR-based assay. Using this method, E. sakazakii (Cronobacter spp.) in PIF can be isolated and identified within one day (24 hours).

• Korean Journal of Clinical Laboratory Science
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• v.50 no.3
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• pp.354-358
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• 2018

When preparing for a blood transfusion, the presence and types of unexpected antibodies should be identified through screening tests. Using the DiaMed-ID system, antibody identification among unexpected antibody screening tests performed at a university hospital in Daejeon area for two years from January 2016 to December 2017 were limited to 55 patients and were predominantly women. A total of 36 patients (65.5%) belonged to the Rh group, 7 (12.7%) patients to the Lewis group, 4 (7.3%) patients to the Kidd and Duffy groups, 3 patients (5.5%) to the MNS group, and 1 (1.8%) to the Rh+Kidd combined group. In the Rh group, 19 (34.5%) patients had Anti-E single antibody, 5 (9.1%) patients had Anti-D single antibody, 4 (7.3%) patients had Anti-E/-c, 4 (7.3%) patients had Anti-C/-e, and 1 (1.8%) patient had $Anti-E/-c/-Jk^b$. In the Lewis group, three (5.5%) patients had both $Anti-Le^a$ and $Anti-Le^b$. In the Kidd group, one (1.8%) patient had $Anti-Jk^a$ and three (5.5%) patients had $Anti-Jk^b$. In the Duffy and MNS groups, only single antibody was found: one (1.8%) patient with $Anti-Fy^a$, three (5.5%) patients with $Anti-Fy^b$, two (3.6%) patients with Anti-M, and one (1.8%) patient with Anti-S. This study reflects the recent frequencies and distributions of unexpected antibodies in Daejeon, which would be helpful for the efficient preparation for transfusions.

• The Korean Journal of Nuclear Medicine
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• v.26 no.2
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• pp.327-332
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• 1992

$^{99m}Tc-dimercaptosuccinic$ acid (DMSA) 주사후 일정시간에 측정한 절대적 신섭취량은 기능이 살아있는 신피질량과 관계있다. 소아의 신기능은 출생후 계속 성숙되어 생후 약 $1\sim2$년에 성인의 기능에 도달하는데 DMSA섭취도 성인과는 다른 양상을 보일 것으로 기대되며 신질환에서 절대적 신섭취율의 평가는 연령을 고려해야 할 것이다. 저자들은 DMSA 스캔을 시행한 소아 환자를 대상으로 스캔상 피질 결손이 없으며 양측신의 섭취율이 비슷하고 혈중 크레아티닌치가 정상인 경우를 대조군으로 하여 연령별 DMSA의 절대적 신섭취율을 구하였고 방광요관역류를 가진 환아를 대상으로 DMSA스캔을 시행하고 신섭취율을 조사하였다. 1) 대조군은 모두 65명으로 좌우측 신섭취율의 유의한 차이는 없었으며 연령에 따라 2세경에 플라토에 도달하였는데 한쪽 신장의 평균섭취율은 3개월 미만이 $14.5{\pm}3.1%$ ID, 3개월에서 6개월 미만이 $17.2{\pm}2.1%$ID, 6개월에서 1년 미만이 $18.4{\pm}1.3%$ID, 1년에서 1년6개월 미만이 $19.3{\pm}1.1%$ID, 1년 6개월에서 2년 미만이 $21.9{\pm}2.0%$ID, 2세이상 15세이하가 $20.1{\pm}0.6%$ID였으며 전체 평균섭취율은 $19.4{\pm}0.5%$ID (injected dose, $mean{\pm}S.E.$)였다. 2) 방광요관역류를 가진 환아는 55명 (일측성 56명, 양측성 29명)으로 109신장을 대상으로 하였다. 방광요관역류의 정도와 피질결손의 수와는 대체로 비례관계가 있었으나 방광요관역류가 없으면서 피질결손이 있는 경우가 25신장중 2예 (8%)였으며, 방광요관역류가 있는 84신장중 27예 (32.1%), 이중에서 방광요관역류가 3도 이상인 62신장중 13예 (21%)에서는 피질결손이 없었다. 3) 이환신의 DMSA 섭취율을 연령에 따른 대조군의 섭취율에 대한 비(섭취율비)로 나타내면 한쪽에 역류가 있을 때 이환신의 경우 $0.55{\pm}0.06$, 정상신의 경우 $1.34{\pm}0.05$이었으며, 양쪽에 역류가 있을 때는 평균 $0.82{\pm}0.08$ $(mean{\pm}S.E.)$ 이었다. 4) 피질결손이 있는 신장의 절대 DMSA 신섭취율은 감소되어 있었고 상대측 신장의 섭취율은 피질 결손이 있더라도 대상적인 증가의 경향을 보였다. 이상의 결과로 소아에서 DMSA 절대적 신섭취율의 연령에 따른 변화를 알 수 있었으며 방광요관역류의 정도와 피질결손의 정도가 반드시 비례하지만은 않아서 시간경과에 따른 추후 검사가 필요하리라 생각된다. 또한 방광요관역류가 있는 환아에서 DMSA 섭취율로 신기능을 평가할 때, 특히 영유아에서 연령에 따른 고려가 있어야 할 것으로 보인다.

• Communications of the Korean Mathematical Society
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• v.21 no.1
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• pp.37-43
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• 2006

We prove that $M_1\longrightarrow^f\;M_2$ is an injective representation of a quiver $Q={\bullet}{\rightarrow}{\bullet}$ if and only if $M_1\;and\;M_2$ are injective left R-modules, $M_1\longrightarrow^f\;M_2$ is isomorphic to a direct sum of representation of the types $E_l{\rightarrow}0$ and $M_1\longrightarrow^{id}\;M_2$ where $E_l\;and\;E_2$ are injective left R-modules. Then, we generalize the result so that a representation$M_1\longrightarrow^{f_1}\;M_2\; \longrightarrow^{f_2}\;\cdots\;\longrightarrow^{f_{n-1}}\;M_n$ of a quiver $Q={\bullet}{\rightarrow}{\bullet}{\rightarrow}{\cdots}{\rightarrow}{\bullet}$ is an injective representation if and only if each $M_i$ is an injective left R-module and the representation is a direct sum of injective representations.