• Title/Summary/Keyword: dose evaluation

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Evaluation of the Radiation Pneumonia Development Risk in Lung Cancer Cases

  • Yilmaz, Sercan;Adas, Yasemin Guzle;Hicsonmez, Ayse;Andrieu, Meltem Nalca;Akyurek, Serap;Gokce, Saban Cakir
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.17
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    • pp.7371-7375
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    • 2014
  • Background: Concurrent chemo-radiotherapy is the recommended standard treatment modality for patients with locally advanced lung cancer. The purpose of three-dimensional conformal radiotherapy (3DCRT) is to minimize normal tissue damage while a high dose can be delivered to the tumor. The most common dose limiting side effect of thoracic RT is radiation pneumonia (RP). In this study we evaluated the relationship between dose-volume histogram parameters and radiation pneumonitis. This study targeted prediction of the possible development of RP and evaluation of the relationship between dose-volume histogram (DVH) parameters and RP in patients undergoing 3DCRT. Materials and Methods: DVHs of 41 lung cancer patients treated with 3DCRT were evaluated with respect to the development of grade ${\geq}2$ RP by excluding gross tumor volume (GTV) and planned target volume (PTV) from total (TL) and ipsilateral (IPSI) lung volume. Results: Were admitted statistically significant for p<0.05. Conclusions: The cut-off values for V5, V13, V20, V30, V45 and the mean dose of TL-GTV; and V13, V20,V30 and the mean dose of TL-PTV were statistically significant for the development of Grade ${\geq}2$ RP. No statistically significant results related to the development of Grade ${\geq}2$ RP were observed for the ipsilateral lung and the evaluation of PTV volume. A controlled and careful evaluation of the dose-volume histograms is important to assess Grade ${\geq}2$ RP development of the lung cancer patients treated with concurrent chemo-radiotherapy. In the light of the obtained data it can be said that RP development may be avoided by the proper analysis of the dose volume histograms and the application of optimal treatment plans.

Verification of Harmonization of Dose Assessment Results According to Internal Exposure Scenarios

  • Kim, Bong-Gi;Ha, Wi-Ho;Kwon, Tae-Eun;Lee, Jun-Ho;Jung, Kyu-Hwan
    • Journal of Radiation Protection and Research
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    • v.43 no.4
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    • pp.143-153
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    • 2018
  • Background: The determination of the amount of radionuclides and internal dose for the worker who may have intake of radionuclides results in a variation due to uncertainty of measurement data and ingestion information. As a result of this, it is possible that for the same internal exposure scenario assessors could make considerably different estimation of internal dose. In order to reduce this difference, internal exposure scenarios for nuclear facilities were developed, and intercomparison were made to determine the harmonization of dose assessment results among the assessors. Materials and Methods: Seven cases on internal exposures incidents that have occurred or may occur were prepared by referring to the intercomparison excercise scenario that NRC and IAEA have carried out. Based on this, 16 nuclear facilities concerned with internal exposure in Korea were asked to evaluate the scenarios. Each result was statistically determined according to the harmonization discrimination criteria developed by IDEAS/IAEA. Results and Discussion: The results were evaluated as having no outliers in all 7 cases. However, the distribution of the results was spread by various causes. They can be divided into two wide categories. The first one is the distribution of the results according to the assumption of the intake factors and the evaluation factors. The second one is distribution due to misapplication of calculation method and factors related to internal exposure. Conclusion: In order to satisfy the harmonization criteria and accuracy of the internal exposure dose evaluation, it is necessary that exact guidelines should be set on low dose, and various intercomparison cases also be needed including high dose exposure as well as the specialized education. The aim of the blind test is to make harmonization evaluation, but it will also contribute to securing the expertise and high quality of dose evaluation data through the discussion among the participants.

Entrance Surface Dose according to Dose Calculation : Head and Wrist (피폭선량 산출을 통한 피부입사선량 계산: 머리 및 손목을 중심으로)

  • Sung, Ho-Jin;Han, Jae-Bok;Song, Jong-Nam;Choi, Nam-Gil
    • Journal of radiological science and technology
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    • v.39 no.3
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    • pp.305-312
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    • 2016
  • This study were compared with the direct measurement and indirect dose methods through various dose calculation in head and wrist. And, the modified equation was proposed considering equipment type, setting conditions, tube voltage, inherent filter, added filter and its accompanied back scatter factor. As a result, it decreased the error of the direct measurement than the existing dose calculation. Accordingly, diagnostic radiography patient dose comparison would become easier and radiogrphic exposure control and evaluation will become more efficient. The study findings are expected to be useful in patients' effective dose rate evaluation and dose reduction.

Secondary Neutron Dose in Carbon-ion Radiotherapy: Investigations in QST-NIRS

  • Yonai, Shunsuke;Matsumoto, Shinnosuke
    • Journal of Radiation Protection and Research
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    • v.46 no.2
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    • pp.39-47
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    • 2021
  • Background: The National Institutes for Quantum and Radiological Science and Technology-National Institute of Radiological Sciences (QST-NIRS) has continuously investigated the undesired radiation exposure in ion beam radiotherapy mainly in carbon-ion radiotherapy (CIRT). This review introduces our investigations on the secondary neutron dose in CIRT with the broad and scanning beam methods. Materials and Methods: The neutron ambient dose equivalents in CIRT are evaluated based on rem meter (WENDI-II) measurements. The out-of-field organ doses assuming prostate cancer and pediatric brain tumor treatments are also evaluated through the Monte Carlo simulation. This evaluation of the out-of-field dose includes contributions from secondary neutrons and secondary charged particles. Results and Discussion: The measurements of the neutron ambient dose equivalents at a 90#x00B0; angle to the beam axis in CIRT with the broad beam method show that the neutron dose per treatment dose in CIRT is lower than that in proton radiotherapy (PRT). For the scanning beam with the energy scanning technique, the neutron dose per treatment dose in CIRT is lower than that in PRT. Moreover, the out-of-field organ doses in CIRT decreased with distance to the target and are less than the lower bound in intensity-modulated radiotherapy (IMRT) shown in AAPM TG-158 (American Association of Physicists in Medicine Task Group). Conclusion: The evaluation of the out-of-field doses is important from the viewpoint of secondary cancer risk after radiotherapy. Secondary neutrons are the major source in CIRT, especially in the distant area from the target volume. However, the dose level in CIRT is similar or lower than that in PRT and IMRT, even if the contributions from all radiation species are included in the evaluation.

A formalism for the absorbed dose evaluation of the glass dosimeter

  • Ka-Young Park;Hyun-Chul Kim;Byoung-Chul Kim
    • Nuclear Engineering and Technology
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    • v.55 no.6
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    • pp.2283-2287
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    • 2023
  • We propose in the present work how the reference glass dosimeters can be introduced, which reflects the user irradiation condition. The reference glass dosimeters are used for correcting the reader fluctuation by reading it with sample glass dosimeters at the same time. Since they can be used without annealing after irradiation for long periods, one should consider both the fading effect and the natural background dose accumulation quantitatively. We construct an empirical but practical formalism of evaluating the absorbed dose on the glass dosimeter with the fading effect and the natural background dose accumulation considered.

Evaluation of DQA for Tomotherapy using 3D Volumetric Phantom (3차원 체적팬텀을 이용한 토모치료의 Delivery Quality Assurance 평가)

  • Lee, Sang-Uk;Kim, Jeong-Koo
    • Journal of radiological science and technology
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    • v.39 no.4
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    • pp.607-614
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    • 2016
  • The study investigates the necessity of 3 dimensional dose distribution evaluation instead of point dose and 2 dimensional dose distribution evaluation. Treatment plans were generated on the RANDO phantom to measure the precise dose distribution of the treatment site 0.5, 1, 1.5, 2, 2.5, 3 cm with the prescribed dose; 1,200 cGy, 5 fractions. Gamma analysis (3%/3 mm, 2%/2 mm) of dose distribution was evaluated with gafchromic EBT2 film and ArcCHECK phantom. The average error of absolute dose was measured at $0.76{\pm}0.59%$ and $1.37{\pm}0.76%$ in cheese phantom and ArcCHECK phantom respectively. The average passing ratio for 3%/3 mm were $97.72{\pm}0.02%$ and $99.26{\pm}0.01%$ in gafchromic EBT2 film and ArcCHECK phantom respectively. The average passing ratio for 2%/2 mm were $94.21{\pm}0.02%$ and $93.02{\pm}0.01%$ in gafchromic EBT2 film and ArcCHECK phantom respectively. There was a more accurate dose distribution of 3D volume phantom than cheese phantom in patients DQA using tomotherapy. Therefor it should be evaluated simultaneously 3 dimensional dose evaluation on target and peripheral area in rotational radiotherapy such as tomotherapy.

Evaluation of Relationship between Radiation Dose and Image Quality according to Source to Image Receptor Distance in Rib Series Radiography (늑골 방사선검사 시 X선관 초점-영상수신체간 거리에 따른 환자선량과 화질의 연관성 평가)

  • Joo, Young-Cheol;Jung, Young-Jin
    • Journal of radiological science and technology
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    • v.41 no.5
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    • pp.391-396
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    • 2018
  • The purpose of this study was to compare and analyze the patient dose according to the distance between the X-ray tube focus and the image receptor, and to propose a new method for quantitatively evaluating the image quality. Using this quantitative evaluation method, the optimal distance for increasing x-ray image quality with low radiation dose was estimated between source and image receptor in Rib series radiography. Phantom images were obtained by changing the distance between focus and image receptor (100 cm and 180 cm). The patient radiation dose was estimated using entrance surface dose and dose area product. In order to evaluate image quality objectively, a non - reference image evaluation method was employed with paper and salt noise and Gaussian filter. As a result of this study, when the SID was changed from 100 cm to 180 cm, the entrance surface dose decreased by 4 ~ 5 times and the dose area product decreased by 3 times. In addition, there is no significant difference in image quality between of SID 180 cm and SID 100 cm. In conclusion, it was demonstrated that performing the rib series radiography at SID 180 cm is an optimal method to reduce the exposure dose and improve the image quality.

Evaluation of Absorbed Dose According to Nanoparticle Density During the Breast Cancer Brachytherapy (유방암 근접치료 시 나노입자의 밀도에 따른 흡수선량 평가)

  • Lee, Deuk-Hee;Nam, Ji-Hee;Kim, Jung-Hoon
    • Journal of radiological science and technology
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    • v.42 no.2
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    • pp.131-135
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    • 2019
  • The purpose of this study was to evaluate the efficacy of brachytherapy of breast cancer by dose assessment which a steady increased in Korea women. The dose assessment was performed using the MCNPX program, a MonteCarlo simulation technique. The sources used for brachytherapy was 192Ir. And nanoparticle which used for dose enhancement was gold. The density of nanoparticle was 7, 18 and 30 mg. Evaluation of absorbed dose according to distance is measured at a distance of 30, 50, 100 and 200 cm from the patient. As a result, The breast absorbed dose results increased in proportion to the density of nanoparticle. And the surrounding organs were not significantly different according to the density. But, in some organs, the absorbed dose decreased as the density of nanoparticles increased. Absorbed dose according to the distance was in inverse proportion to distance.

Evaluation of the effective dose and image quality of low-dose multi-detector CT for orthodontic treatment planning (3차원 안모분석을 위한 저선량 Multi-detector CT 영상의 유효선량 및 화질 평가)

  • Chung, Gi-Chung;Han, Won-Jeong;Kim, Eun-Kyung
    • Imaging Science in Dentistry
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    • v.40 no.1
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    • pp.15-23
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    • 2010
  • Purpose : This study was designed to compare the effective doses from low-dose and standard-dose multi-detector CT (MDCT) scanning protocols and evaluate the image quality and the spatial resolution of the low-dose MDCT protocols for clinical use. Materials and Methods : 6-channel MDCT scanner (Siemens Medical System, Forschheim, Germany), was used for this study. Protocol of the standard-dose MDCT for the orthodontic analysis was 130 kV, 35 mAs, 1.25 mm slice width, 0.8 pitch. Those of the low-dose MDCT for orthodontic analysis and orthodontic surgery were 110 kV, 30 mAs, 1.25 mm slice width, 0.85 pitch and 110 kV, 45 mAs, 2.5 mm slice width, 0.85 pitch. Thermoluminescent dosimeters (TLDs) were placed at 31 sites throughout the levels of adult female ART head and neck phantom. Effective doses were calculated according to ICRP 1990 and 2007 recommendations. A formalin-fixed cadaver and AAPM CT performance phantom were scanned for the evaluation of subjective image quality and spatial resolution. Results : Effective doses in ${\mu}Sv$ ($E_{2007}$) were 699.1, 429.4 and 603.1 for standard-dose CT of orthodontic treatment, low-dose CT of orthodontic analysis, and low-dose CT of orthodontic surgery, respectively. The image quality from the low-dose protocol were not worse than those from the standard-dose protocol. The spatial resolutions of both standard-dose and low-dose CT images were acceptable. Conclusion : From the above results, it can be concluded that the low-dose MDCT protocol is preferable in obtaining CT images for orthodontic analysis and orthodontic surgery.

Evaluation of Radiation Dose to Patients according to the Examination Conditions in Coronary Angiography (심장동맥 조영 검사 시 검사 조건에 따른 환자 선량 평가)

  • Yong-In Cho
    • Journal of radiological science and technology
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    • v.46 no.6
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    • pp.509-517
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    • 2023
  • This study analyzed imaging conditions and exposure index through clinical information collection and dose calculation programs in coronary angiography examinations. Through this, we aim to analyze the effective dose according to examination conditions and provide basic data for dose optimization. In this study, ALARA(As Low As Reasonably Achievable)-F(Fluoroscopy), a program for evaluating the radiation dose of patients and the collected clinical data, was used. First, analysis of imaging conditions and exposure index was performed based on the data of the dose report generated after coronary angiography. Second, after evaluating organ dose according to 9 imaging directions during coronary angiography, with the LAO fixed at 30°, dose evaluation was performed according to tube voltage, tube current, number of frames, focus-skin distance, and field size. Third, the effective dose for each organ was calculated according to the tissue weighting factors presented in ICRP(International Commission on Radiological Protection) recommendations. As a result, the average sum of air kerma during coronary angiography was evaluated as 234.0±112.1 mGy, the dose-area product was 25.9±13.0 Gy·cm2, and the total fluoroscopy time was 2.5±2.0 min. Also, the organ dose tended to increase as the tube voltage, milliampere-second, number of frames, and irradiation range increased, whereas the organ dose decreased as the FSD increased. Therefore, medical radiation exposure to patients can be reduced by selecting the optimal tube voltage and field size during coronary angiography, maximizing the focal-skin distance, using the lowest tube current possible, and reducing the number of frames.