• Journal of Oriental Neuropsychiatry
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• v.20 no.2
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• pp.217-227
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• 2009

Objectives : Multiple sclerosis (MS) is a demyelination disease of central nervous system, presenting a various neurological disorders depending on the lesion. In the view of oriental medicine, MS is similar to Flaccidity-syndrome(痿證). Also, since MS is a chronic disease which repeats the recurrences with periods of remission of the symptoms in between, it may usually be accompanied by depression. However, the etiology, treatment, and cause of recurrence of MS remain unknown, and also, as the recurrences of MS have been repeated, disease burden has been accumulated, which aggravates disorder. This case of MS experienced depression after the patient had been diagnosed as bad consequence based on the past 5 times recurrences of multiple sclerosis. Methods : We saw the causes as vicera and bowels functional disorder which might have come from a poor diet. Thus, we diagnosed this case as dual deficiency of spleen and kidney(脾腎兩虛), stagnant qi transforming into fire(氣鬱化火) and liver-kidney deficiency(肝腎不足) and treated it with Herb medication, acupuncture therapy, and supportive therapy, making the patient better. Results : We have improved the patient's condition to the time before 5th recurrence. Conclusions : This result suggests that our oriental medical treatments was effective on multiple sclerosis with depression.

• The Journal of Internal Korean Medicine
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• v.44 no.2
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• pp.197-206
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• 2023

Objesctives: This study reports the effect of Korean medicine treatment on a patient with abdominal and lower back pain after a laparoscopic hysterectomy. Methods: The patient received Korean herbal medicine, pharmacopuncture treatment, and acupuncture treatment for six days. We measured the numeric rating scale (NRS), Oswestry Disability Index (ODI), Range of Motion (ROM), and Life-5 Dimensions scale (EQ-5D) to assess symptom changes. Results: After treatment, the patient showed decreased numeric rating scale (NRS) and Oswestry Disability Index (ODI), as well as augmented Range of Motion (ROM) and European Quality of Life 5 Dimensions scale (EQ-5D). Conclusion: The results indicate that Korean medicine treatment is effective management for patients with abdominal and lower back pain after a laparoscopic hysterectomy.

• The Journal of Korean Obstetrics and Gynecology
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• v.33 no.3
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• pp.175-186
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• 2020

Objectives: The purpose of this study is to report the effect of Jokyeongjongok-tang-gami in case of oligomenorrhea patients classified with gan-ulgiche and eumheo due to polycystic ovary syndrome. Methods: Three patients suffering from oligomenorrhea due to polycystic ovary syndrome were treated with korean medical treatment (herbal medicine, moxibustion, acupuncture) more than 3 months. The patients classified with gan-ulgiche and eumheo were treated with Jokyeongjongok-tang-gami. Results: Three oligomenorrhea patients recovered normal menstrual cycle more than 3 times after taking Korean medical treatment for 3~6 months. Conclusions: This 3 cases classified with gan-ulgiche and eumheo show Jokyeongjongok-tang-gami is effective on patients with rare menstruation due to polycystic ovary syndrome.

• The Journal of Pediatrics of Korean Medicine
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• v.21 no.2
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• pp.97-107
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• 2007

Objectives This experiment is about Jojoongikgi-tang(JIT) exerts anti-inflammatory effects in BV2 microglial cells, and the effect of JIT on Nitric oxide(NO) production in lipopolysaccharide(LPS)-stimulated BV2 microglial cells were also demonstrated. Methods To investigate the anti-inflammatory effects of JIT, NO production, expression level of iNOS mRNA, PGE2 synthesis, expression COX-2 mRNA, cell viability, $TNF-{\alpha}$ mRNA expression were examined. Results The expression level of inducible nitric oxide synthase(iNOS) was decreased by JIT, and the production of Prostaglandin E2(PGE2) and the expression of Cox-2 mRNA also were inhibited by JIT. Proinflammatory mediators, such as $TNF-{\alpha}$, $IL-1{\beta}$, IL-12, were inhibited by JIT in a dose-dependent manner. Conclusions JIT have anti-inflammatory effects in BV2 microglial cells and could be used in inflammatory disease.

• Journal of Acupuncture Research
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• v.28 no.5
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• pp.143-151
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• 2011

Objectives : The purpose of this study is to report the effect of acupotomy for patient with avascular necrosis(AVN) of femur head. Methods : Three patient who had been diagnosed as AVN participated in this study. The patient treated by acupotomy therapy. After the treatment, the patient was measured by visual analogue scale(VAS), Harris hip score and five likert scale Results : The patient informed the researcher of reduced pain and improved range of movement after the conduct of acupotomy therapy. The efficacy of acupotomy treatment was reaffirmed by the results of the VAS, physical examination (ROM, Patrcik sign), Harris hip score. Conclusions : Acupotomy therapy on AVN of femur head shows the efficacy in reducing pain and improving movement.

• Journal of Acupuncture Research
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• v.27 no.2
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• pp.59-69
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• 2010

Objectives : This study was designed to investigate effects of Lumbricus pharmacopuncture (LP) on the lipid lowering, anti-oxidative activity and concentration of proinflammatory cytokines in rat fed high fat diet. Methods : Sprague-Dawley male rats were fed high fat diet for 8 weeks and experimental groups were divided into 4 groups as follows : Control, Lumbricus Jungwan ($CV_{12}$) pharmacopuncture (T I), Lumbricus Joksamni ($ST_{36}$) pharmacopuncture (T II), Lumbricus Jungwan ($CV_{12}$) and Joksamni ($ST_{36}$) pharmacopuncture (T III). Results : The levels of plasma FFA, TG, total cholesterol, LDL-C, TBARS, IL-$1{\beta}$, IL-6, TNF-$\alpha$ and liver total cholesterol, TG, TBARS, SOD, catalase, IL-6 in more than one LP group were significantly lower than those of Control groups. The level of IL-10 in one of LP groups was significantly higher than that of Control group. Conclusions : As the results were shown, LP treatment have considerable effects on lipid lowering, anti-oxidative activity and concentration of proinflammatory cytokines in rat fed high fat diet.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.5 no.2
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• pp.135-149
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• 2010

Objectives : This study was designed to observe the effect of Chuna manual therapy on the asymmetrical alignment. Methods : To analyze static structural alignment, posterior inferior ilium deviation(PI), inflare change of pelvis were checked from full spine AP X-ray. And Cobb's angle of spine and height of shoulder girdle were analyzed. To evaluate the pain visual analogue score(VAS) was scored. Chuna therapy treated 8-10 times for 1 month. Results and Conclusions : In 3 cases, VAS was improved significantly. Full spine AP X-ray shows improvement of structural imbalace. Shoulder height difference, cobb's angle, pelvic insufficiency improved considerably. These results suggest that Chuna therapy might be effective for malalignment patients.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.4
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• pp.919-923
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• 2006

Sebum is an oily substance produced by sebaceous glands in human skin. The differentiation of the sebaceous gland is remarkably species-specific and sebocytes may play crucial parts in the pathophysiologic processes and disorders of pilosebaceous unit. In this study, we investigated the inhibitory effect of Ficis folium on the lipid production using the human sebocyte cell line 5195. Our results showed that Ficis folium significantly inhibits synthesis of sebaceous lipids such as cholesterol esters, triglycerides, and total lipid. And Ficis folium supressed cytoplasmic lipid droplets. On the other hand, Ficis folium didn't effect on cell proliferation. These results suggest treatment with Ficis folium resulted in a lower lipid synthesis in SZ95 cells without cytotoxicity.

• Journal of Sasang Constitutional Medicine
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• v.28 no.4
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• pp.372-380
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• 2016

Objectives We report a case which is based on Sasang constitutional Medicine for Soyangsangpungjeung of Soyangin who has chill and fever. Methods We have treated a Soyangin patient that had chill and fever which was diagnosed as Soyangsangpungjeung. We prescribed oriental medicine therapy focused on herbal medicine for that physical symptoms. The improvement of that symptoms was evaluated. Results After using oriental medicine therapy, patient's physical symptoms were improved. Conclusions This case study showed an efficient result of using oriental medicine therapy, especially herbal medicine in Soyangsangpungjeung of Soyangin.

• 대한상한금궤의학회지
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• v.13 no.1
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• pp.145-153
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• 2021

Objective : This study aimed to report the improvement of a patient with anorexia by treatment with Jinmu-tang (Hyunmu-tang) based on the disease pattern identification diagnostic system (DPIDS) of the Shanghanlun provisions. Methods : We evaluated the progress of symptoms, patient compliance, and presence of side effects after the patient was administered Jinmu-tang. The clinical response was estimated according to the number of meals a day, the size of meals, the number of complaints of abdominal pain in a week, and a Likert scale. Results : According to the DPIDS, the patient was diagnosed according to provision 316 with soyinbing. After administration of Jinmu-tang for 45 days, the number of meals a day and the size of meals increased, the number of complaints of abdominal pain in a week decreased, and the Likert scale score decreased from 3 to 0. Conclusions : This case report suggests that the word "腹痛" (abdominal pain) in the 316th Shanghanlun provision indicates anxiety about abdominal pain, which affected anorexia in this case.