The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)
- Volume 21 Issue 2
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- Pages.97-107
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- 2007
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- 1226-8038(pISSN)
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- 2287-9463(eISSN)
Inhibitory Effects of Jojoongikgi-tang on the Secretion of PGE2 and NO and Cytokines in LPS-stimulated BV2 Microglial Cells
- Lee, Jun-Moon (Department of Pediatrics, College of Oriental Medicine, Dong-Eui University) ;
- Lyu, Sun-Ae (Department of Pediatrics, College of Oriental Medicine, Dong-Eui University) ;
- Lee, Seung-Yeon (Department of Pediatrics, College of Oriental Medicine, Dong-Eui University Clinical Research Center of Oriental Medicine, Dong-Eui University) ;
- Kim, Bo-Kyung (Department of Neuropsychiatry, College of Oriental Medicine, Dong-Eui University) ;
- Ko, Woo-Shin (Department of Oriental Medical Ophthalmology & Otolaryngology &Dermatology, College of Oriental Medicine, Dong-Eui University)
- Published : 2007.08.31
Abstract
Objectives This experiment is about Jojoongikgi-tang(JIT) exerts anti-inflammatory effects in BV2 microglial cells, and the effect of JIT on Nitric oxide(NO) production in lipopolysaccharide(LPS)-stimulated BV2 microglial cells were also demonstrated. Methods To investigate the anti-inflammatory effects of JIT, NO production, expression level of iNOS mRNA, PGE2 synthesis, expression COX-2 mRNA, cell viability,