• Title/Summary/Keyword: data-based model

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The Current Research Methodology of Pharmacopucture for the Treatment of Animal Cancer Models in Korea (암에 대한 약침치료의 국내 동물모델 연구 현황)

  • Ryu, Hee Kyoung;Goo, Bon Hyuk;Suk, Kyung Hwan;Lee, Ju Hyeon;Ryu, Soo Hyeong;Lee, Su Yeon;Kim, Min Jeong;Park, Yeon Cheol;Baek, Yong Hyeon;Park, Dong Suk;Seo, Byung Kwan
    • Journal of Acupuncture Research
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    • v.31 no.4
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    • pp.81-97
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    • 2014
  • Objectives : The purpose of this study is analyzing the current research methodology of pharmacopucture for the treatment of animal cancer models. Methods : Four electronic databases were searched for animal studies published from January 2000 to September 2014 onward using these search terms "cancer, anticancer, pharmacopuncture, beevenom". Selected articles were described about animal cancer models. The methods used to induce cancer and the outcome measures used to assess the effects of pharmacopuncture on animal cancer models were analyzed. Results : 37 articles were included. For producing animal cancer models BALB/C mice(n=22) and C57BL/6 mice(n=17) were selected. And intravenous injection of B16-F10 melanoma cells into tail vein(n=14) or intraperitoneal injection of sarcoma-180 cells(n=14) were frequently used to induce cancer. Various pharmacopunctures were injected into acupoints $CV_{12}(n=19)$, $ST_{36}(n=8)$, $BL_{18}(n=8)$ or peritoneal cavity(n=6), tumor site(n=2), tail vein(n=2). Outcome measures were categorized into anti-cancer, anti-metastasis, general condition, cytotoxicity, immune response, toxicity. Median Survival Time(MST) and increase of life span(ILS)(n=26) was frequently used for evaluating anti-cancer effects. And pulmonary colonization assay(n=13) was frequently used for evaluating anti-metastasis effects Conclusions : Based on these data, further research would be needed to ascertain the effectiveness of pharmacopuncture for treating cancer and broaden the range of clinical applications.

The Study on Health Promoting Lifestyle of the Elderly (노인의 건강증진 생활양식에 관한 연구)

  • 송영신;이미라;안은경
    • Journal of Korean Academy of Nursing
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    • v.27 no.3
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    • pp.541-549
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    • 1997
  • This study was done to describe health promoting lifestyle and determine affecting factors in elderly based on the Heath Promotion Model by Pender. Cognitive-perceptual factors that were included in this study were self-efficacy and hardiness. Modifying factors were demographic characteristics (sex, age, partner, previous illness, education level. income and religion). The specific purpose of this study was to examine the relationships of self-efficacy, hardiness and the demographic chasteristics to health promoting lifestyle and to determine causal factors affecting the elderly. The subjects were a volunteer sample of 98 elderly in one city in? The instruments for this study were Health Promoting Lifestyle Profile(47items, 4scale), Health Related Hardiness Scale(22i1ems, 6scale), general Self-Efficacy Scale(13i1ems, 5scale). Frequency, percentage, t-test, ANOVA, Pearson's correlation coefficient and Stepwise Multiple regression technique with SAS program were used to analyse the data. The Results of the study are as follows : 1) The average item score for the health promoting lifestyle was 2.63, the highest score on the subscales was interpersonal support (M=3.3), followed by self-actulization(M=2.9), nutrition(M=2.8), stress management(M=2.7), health responsibility(M=2.1) with the lowest bring exercise(M=2.0) 2) A significant difference between education level, income, religion and health promoting lifestyle were found. 3) All of the subscales on health promoting lifestyle were positively related to total hardiness (r=0.330, p<0.001). The hardiness subscale of control was positively related to self-actulization(r=0.276, p<0.01), and commitment was positively related to self-actualization(r=0.315, p<0.001), exercise /nutrition(r=0.245, p<0.01), interpersonal support(r=0.278, p<0.01), stress management(r=0.250, p<0.01). Challenge was positively related to self-actualization(r=0.315, p<0.001), exercise /nutrition(r=0.245, p<0.01). There was no significant correlation between self-efficacy and all of the subscales of health promoting lifestyle. Self-efficacy showed a significant correlation only with control(r=0.469, p<0.001), comittment(r=0.507, p<0.001), challenge (r=0.489, p< 0.001). 4) Comittment, self-efficacy and income explained 25.01% of the variance for the total health promoting lifestyle. The results of this study show that commitment, self efficacy and income predicted the health promoting lifestyle of the elderly. So health promoting programs that increase commitement and self-efficacy should be developed to promote a healthy lifestyle of the elderly, especially those who have low income.

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Usability Evaluation Framework for Ubiquitous Computing Device (유비쿼터스 디바이스를 위한 사용성 평가 프레임워크 개발 - 디바이스의 Graphical User Interface 중심으로)

  • Kim, Han-Joon;Choi, Jong-Kyu;Ji, Yong-Gu
    • 한국HCI학회:학술대회논문집
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    • 2008.02b
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    • pp.131-135
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    • 2008
  • Nowadays various information devices using electronic technology has been released. And these digital devices will be continuously developed to make a satisfaction of customer's needs. So digital device will support network service using communication technology, so users will use the internet service anywhere, anytime. Also the networked device which is used in ubiquitous computing environment should be evaluated by new evaluation framework. Therefore previous usability evaluation framework need to reflect the characteristics of ubiquitous computing. However most of pervious research about ubiquitous computing was about conceptual issues like rules and characteristics of ubiquitous computing, so the research of usability testing and evaluation method for ubiquitous computing is rarely conducted. This research's purpose is developing the evaluation framework for ubiquitous computing device and usability model for ubiquitous computing. To develop the evaluation framework, we collect the evaluation indexes which have need used in GUI evaluation And we extract evaluation indexes for ubiquitous computing based on literature review.

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A Study on the Factors Affecting the Qualities of Lives in Mothers with Disabled Children in Seoul (서울 지역 장애아어머니의 삶의 질에 영향을 미치는 제 요인에 관한 연구)

  • Yoo, Hye-Kyung
    • Journal of Families and Better Life
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    • v.27 no.1
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    • pp.73-88
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    • 2009
  • The purpose of this study was to investigate the influence of the factors such as self-esteem, social supports, socio-economic status of parents, degree of disability in child, stress coping, religion, and sports.exercise on the qualities of lives in mothers with disabled children. Data were collect from 45 institutions(schools from kindergarten to senior-high, special education institutes, and social welfare institutions) by self-report questionnaire, and the subjects of the study were 386 mothers in Seoul whose children were attending the schools or institutions. Findings according to socio-demographic variables are as follows: 1. Mothers with disabled children in this study thought their quality of life as average degree. 2. The younger the mothers and children, the higher the quality of life was. 3. The higher the educational level and monthly income, the higher the quality of life was. 4. There was no statistically significant difference between the existence and nonexistence of spouse, and between the existence and nonexistence of religion as well. Findings analyzed by multiple regression are as follows: 1. Among 7 independent variables 'self-esteem'(${\beta}$=.49, p<.001), 'social supports'(${\beta}$=.15, p<.01), and 'socio-economic status'(${\beta}$=.11, p<.05) were found to be statistically significant in quality of life in mothers, while the rests were found not significant. 2. 'Self-esteem' was found to be the most influencing variable, meaning that the psychological factor such as self-esteem is more important than environmental factors in qualities of lives in mothers. 3. The total amount of explanation of the model was Adjusted R square=.301, so that it can be said about 30% can be explained among total variance of the qualities of lives in mothers with disabled children. Conclusions and recommendations based on the results above are: First, it is strongly recommended to conduct programs promoting self-esteem in mothers with disabled children, and to include 'self-esteem' hereafter in the studies related to qualities of lives in mothers with disabled children. Second, comprehensive and practical countermeasures should to be formulated to back up expenses for education and medical care, purchasing relative tools and equipments, plus helping to find jobs.

Temperature-Dependency Thermal Properties and Transient Thermal Analysis of Structural Frames Exposed to Fire (온도의존성 열특성 계수를 고려한 화재에 노출된 철근콘크리트 골조의 해석적 연구)

  • Han, Byung-Chan;Kwon, Young-Jin;Kim, Jae-Hwan;Shin, Yeong-Soo;Choi, Eun-Gyu
    • Journal of the Korea Concrete Institute
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    • v.19 no.3
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    • pp.283-292
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    • 2007
  • A research projects is currently being conducted to develop a nonlinear finite element analysis methods for predicting the structural behavior of reinforced concrete frame structures, exposed to fire. As part of this, reinforced concrete frames subjected to fire loads were analyzed using the nonlinear finite-element program DIANA. Two numerical steps are incorporated in this program. The first step carries out the nonlinear transient heat flow analysis associated with fire and the second step predicts the structural behavior of reinforced concrete frames subjected to the thermal histories predicted by first step. The complex features of structural behavior in fire conditions, such as thermal expansion, plasticity, cracking or crushing, and material properties changing with temperature are considered. A concrete material model based on nonlinear fracture mechanics to take cracking into account and plasticity models for concrete in compression and reinforcement steel were used. The material and analytical models developed in this paper are verified against the experimental data on simple reinforced concrete beams. The changes in thermal parameters are discussed from the point of view of changes of structure and chemical composition due to the high temperature exposure. Although, this study considers codes standard fire for reinforced concrete frame, any other time-temperature relationship can be easily incorporated.

The Influence of Problem-solving ability and Critical thinking on the Major Satisfaction of Dental Hygiene Student -Focused on Mediating Effects of Critical Thinking- (치위생 전공 학생의 문제해결능력과 비판적사고가 전공만족도에 미치는 영향 -비판적사고의 매개효과를 중심으로-)

  • Eom, Suk;Choi, Yu-Jin;Lee, Byung-Ho
    • Journal of the Korea Convergence Society
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    • v.10 no.12
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    • pp.151-158
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    • 2019
  • This study was conducted to identify the level of problem-solving ability, critical thinking and satisfaction level of students majoring in dental hygiene, and to identify the impact of problem-solving ability and critical thinking on major satisfaction levels. The research target collected data through a structured questionnaire for 259 students majoring in dental hygienics located in North and South Gyeongsang Province. The analysis results showed that the problem-solving ability of the study subjects was 2.56, critical accidents were 2.58, and the major satisfaction level was 2.32, and the problem-solving ability, critical thinking and major satisfaction level were positively correlated with each other. Among the lower factors of problem solving ability, solution performance and solution model were significant factors that could improve major satisfaction, and among the lower factors of critical thinking, intellectual fairness, intellectual passion/interest, and systematicness were significant factors that could improve major satisfaction. Critical thinking also significantly mediated problem solving ability and major satisfaction level (β=).2602, BCCI [.0908~.4529]). Based on the results, it is believed that dental hygiene education needs to be developed in addition to the establishment of an educational environment that can enhance the ability to solve problems and critical thinking, and that research should be continued to check its effects.

The Relationship between Health Related Physical Fitness, Depression, and Quality of Life of the Elderly (노인의 건강체력과 우울, 삶의 질 관계 : 인지기능을 매개변수로)

  • Chun, Myung-Up;Choi, Jae-Won;Kang, Sung-Goo;Yoo, Ha-Na;Lee, Kyung-Ha
    • Journal of the Korea Convergence Society
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    • v.10 no.12
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    • pp.387-397
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    • 2019
  • The purpose of this study is to analyze the relationship between health related physical fitness, cognitive function, depression and quality of life variables of elderly people in a comprehensive way based on quantitative evaluation. The subjects of this study were 385 people who voluntarily participated in the elderly welfare center in Gyeonggi and Seoul the elderly people. As for the data collection methods, were measured the characteristics, depression and quality of life, cognitive function questionnaires along with measures of lower and upper body strength, dynamic equilibrium and agility, total endurance and grip strength. As a result, the first was a statistically significant correlation between integrated health of the elderly, cognitive function, quality of life and depression. Second, the analysis of cognitive function, elderly integrated health, quality of life, and depression revealed statistical significance among all variables. Third, there was the partial intervention effect of function in the quality of life and depression of the elderly.

Impact of Boundary Conditions and Cumulus Parameterization Schemes on Regional Climate Simulation over South-Korea in the CORDEX-East Asia Domain Using the RegCM4 Model (CORDEX 동아시아 영역에서 경계조건 및 적운모수화방안이 RegCM4를 이용한 남한 지역 기후모의에 미치는 영향 분석)

  • Oh, Seok-Geun;Suh, Myoung-Seok;Myoung, Ji-Su;Cha, Dong-Hyun
    • Journal of the Korean earth science society
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    • v.32 no.4
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    • pp.373-387
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    • 2011
  • In this study, four types of sensitivity experiments (EG, EE, NG, NE; E: ERA-Interim, N: NCEP/DOE2, G: Grell scheme, E: Emanuel scheme) were performed to evaluate the simulation skills of RegCM4 released in July 2010 over the CORDEX (COordinated Regional Downscaling EXperiment) East Asia domain based on the combinations of boundary conditions (BC: ERA-Interim, NCEP/DOE2) and the cumulus parameterization schemes (CPS: Grell, Emanuel) for the 1989. The surface air temperature and precipitation data observed by the Korea Meteorological Adminstration were used to validate the simulation results over South Korea. The RegCM4 well simulates the seasonal and spatial variations of temperature but it fails to capture the seasonal and spatial variations of precipitation without consideration of the BC and CPS. Especially the simulated summer precipitation amount is significantly less in EG, NG, and NE experiments. But the seasonal variation of precipitation including summer precipitation is relatively well simulated in the EE experiment. The EE experiment shows a better skill in the seasonal march of East Asia summer monsoon, distribution of precipitation intensity and frequency than other experiments. In general, the skills of RegCM4 for temperature and precipitation are better during winter than summer, and in Emanuel than Grell schemes. The simulation results are more impacted by cumulus parameterization schemes than boundary conditions.

An Analysis of Inquiry Activities of the High School Common Science Textbook(Materials Part) By Using 3-Dimensional Analysis Framework (3차원 분석틀을 이용한 고등학교 공통과학(물질 부분) 교과서의 탐구 활동 분석)

  • Kim, Yun-Hi;Moon, Seong-Bae
    • Journal of The Korean Association For Science Education
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    • v.20 no.2
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    • pp.274-287
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    • 2000
  • This study was performed the analysis of four kinds of common science textbooks based on the 6th curriculum. Particularly, inquiry activity part was analyzed by the three dimension framework which consists of inquiry content dimension, inquiry process dimension and inquiry context dimension. In the analysis of the inquiry content dimension of inquiry activities, the contents revised by 6th curriculum of common science textbook was accomplished through various inquiry activities. The number of inquiry activity in four textbooks was similar as about 16. The For the analysis of inquiry process dimension, 'interpreting data and formulating generalizations' category (39.1%) was most emphasized and the categories of 'observation and measuring'(30.8%), and 'building, testing and revising the theoretical model' (16.5 %), 'seeing a problem and seeking ways to solve it' (13.5%) follow in order. As for the analysis of the inquiry context dimension, the proportion of STS related contents in inquiry activities was only 18%. So, we propose that STS related contents would increase the proportion for the following textbook.

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An Emotional Self-Regulation Program for Obese Children: Pilot Study Using Mixed Methods (비만아동을 위한 정서적 자기조절 프로그램의 개발 및 효과: 혼합방법론의 적용)

  • Kim, Hee-Soon;Ma, Yu-Mi;Park, Ji-Young;Kim, Seung-Hyun
    • Child Health Nursing Research
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    • v.19 no.3
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    • pp.187-197
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    • 2013
  • Purpose: The purpose of the study was to develop an emotional self-regulation program for obese children and to examine the program's effectiveness on depression, eating habits, and body mass index. Methods: The emotional self-regulation program was developed from theory-based strategies and a pre-post pilot study was conducted with 46 children (19: intervention, 27: control). The program included 6 weekly group sessions over 2 months. The embedded experimental model of concurrent mixed methods was used to better understand research outcomes by converging both quantitative and qualitative data. Anthropometric measurements and surveys were performed before and after the intervention. Three focus group interviews were conducted with all participants after intervention to explore their experiences. Results: The intervention group displayed decreased depression levels in the quantitative outcomes. The participants also expressed positive outcomes such as improvements in confidence, impulse management, intimacy, happiness, and losing weight. Conclusion: These findings suggest that emotional self-regulation skills are crucial factors for obese children not only to manage their emotional problems but also to control their weight. Further research is needed with a larger sample size and randomized controlled trials.