• Title/Summary/Keyword: damage prevention

Search Result 1,599, Processing Time 0.028 seconds

Effects of Polygoni Multiflori Radix on prevention of hyperlipidemia and liver damage induced by alcohol (하수오(何首烏)가 알콜 투여로 유발된 흰쥐의 고지혈증과 간 손상의 예방에 미치는 영향)

  • Jang, Young Eun;Park, Ji Ha;Roh, Seong Soo;Koo, Jin Suk;Seo, Bu Il
    • The Korea Journal of Herbology
    • /
    • v.30 no.3
    • /
    • pp.77-82
    • /
    • 2015
  • Objectives : The Korean medical doctors use PMR(Polygoni Multiflori Radix) for nourishing the liver-kidney, loosing the bowel to relieve constipation, recovering from malaria, and clearing away heat and eliminating toxin, etc. But, this study was performed to investigate the effect of water extracts from PMR on prevention of hyperlipidemia and liver damage induced by alcohol. Methods : Except for the normal group, we fed rat on 25% alcohol for 55 days. And the extract was administrated for the same period. We measured the serum components in rat's blood, body weight and weight of liver. Results : At first, we observed effects of PMR on prevention of hyperlipidemia induced by alcohol. PMR group showed significant decrease of total cholesterol and triglyceride in comparison with those of the control group. PMR group showed significant increase of body weight in comparison with those of the control group in 4weeks and 8weeks. At second, we observed effects of PMR on prevention of liver damage induced by alcohol. PMR group showed significant decrease of GOT, GPT, ALP, and LDH in comparison with those of the control group. PMR group showed significant increase of liver weight in comparison with those of the control group. Conclusions : Reviewing these experimental results, it appears that water extracts from PMR have pharmaceutical efficacy on prevention of hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.

Effects of Saengkankeonbi-tang on Prevention of Hyperlipidemia and Liver Damage Induced by Alcohol (생간건비탕(生肝健脾湯)이 알코올 투여로 유발된 흰쥐의 고지혈증과 간 손상의 예방에 미치는 영향)

  • Hwang, Soo-Jin;Choi, Hong-Sik;Kim, Seung-Mo;Woo, Chang-Hoon
    • The Korea Journal of Herbology
    • /
    • v.24 no.4
    • /
    • pp.9-16
    • /
    • 2009
  • Objectives : This study was performed to investigate the effect of water extracts from Saengkankeonbi-tang on prevention of hyperlipidemia and liver damage induced by alcohol. Methods : Except for the normal group, we fed rats the control and Saengkankeonbi-tang groups with 25% alcohol for 55 days. For the same period we fed the Saengkankeonbi-tang group with Saengkankeonbi-tang extract as well and rats in normal and contrlo group on saline solution. We measured the serum components in rat's blood, body weight and weight of liver. Results : 1. At first, we observed effects of Saengkankeonbi-tang on prevention of hyperlipemia induced by alcohol. Saengkankeonbi-tang group showed significant decrease in total cholesterol levels in comparison with those of the control group. Saengkankeonbi-tang group showed significant increase in HDL-cholesterol levels in comparison with those of the control group. Saengkankeonbi-tang group showed significant increase of body weight in comparison with those of the control group in 4weeks and 8weeks. 2. At second, we observed effects of Saengkankeonbi-tang on prevention of liver damage induced by alcohol. Saengkankeonbi-tang group showed significant decrease in GOT, GPT, LDH and ALP levels in comparison with those of the control group. Saengkankeonbi-tang group showed significant increase of liver weight in comparison with those of the control group. Conclusions : Reviewing these experimental results, it appears that water extracts from Saengkankeonbi-tang have pharmaceutical efficacy on prevention of hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.

Prevention Meteorological Database Information for the Assessment of Natural Disaster (자연재해 평가를 위한 방재기상 DB 정보)

  • Park, Jong-Kil;Jung, Woo-Sik;Choi, Hyo-Jin
    • Journal of the Korean Society of Hazard Mitigation
    • /
    • v.7 no.3
    • /
    • pp.41-49
    • /
    • 2007
  • In order to reduce the amount of damage from natural disasters and perform the natural disaster mitigation program, the prevention activities and forecasting based on meteorological parameters and disaster datas are required. In addition, it is necessary to process prevention meteorological information for prevention activities in advance. For this, we have analyzed four data, such as Statistical yearbook of calamities and Statistics Yearbook issued by the Ministry of Government Administration and Human affairs. And Annual Climatological Report issued by the Korea Meteorological Administration and Recently 10 years for natural disaster damage from the Central Disaster and Safety Countermeasures Headquarters. We analyzed the causes, elements, occurrence frequencies, and vulnerable areas of natural disaster, using the 4 disaster datas, but these datas was not consistent with their terminology and items. Through the analysis of a kind and damage of disaster, we have selected the disaster variables, such as causes and elements, the amount of damage, vulnerable areas of natural disaster, etc and made a database. This database will be used to assess the natural disasters and develop the risk model and natural disasters mitigation plan.

Damage constitutive model of brittle rock considering the compaction of crack

  • Gu, Qingheng;Ning, Jianguo;Tan, Yunliang;Liu, Xuesheng;Ma, Qing;Xu, Qiang
    • Geomechanics and Engineering
    • /
    • v.15 no.5
    • /
    • pp.1081-1089
    • /
    • 2018
  • The deformation and strength of brittle rocks are significantly influenced by the crack closure behavior. The relationship between the strength and deformation of rocks under uniaxial loading is the foundation for design and assessment of such scenarios. The concept of relative crack closure strain was proposed to describe the influence of the crack closure behavior on the deformation and strength of rocks. Considering the crack compaction effect, a new damage constitutive model was developed based on accumulated AE counts. First, a damage variable based on the accumulated AE counts was introduced, and the damage evolution equations for the four types of brittle rocks were then derived. Second, a compaction coefficient was proposed to describe the compaction degree and a correction factor was proposed to correct the error in the effective elastic modulus instead of the elastic modulus of the rock without new damage. Finally, the compaction coefficient and correction factor were used to modify the damage constitutive model obtained using the Lemaitre strain equivalence hypothesis. The fitted results of the models were then compared with the experimental data. The results showed that the uniaxial compressive strength and effective elastic modulus decrease with an increase in the relative crack closure strain. The values of the damage variables increase exponentially with strains. The modified damage constitutive equation can be used to more accurately describe the compressive deformation (particularly the compaction stage) of the four types of brittle rocks, with a coefficient of determination greater than 0.9.

Comparative Analysis between a Real-Life Explosion Case and A Damage Prediction Program (J도 LPG충전소 가스 누출로 인한 폭발사례와 피해예측 프로그램의 비교 분석)

  • Yongho Yang;Soonju Kim;Hasung Kong
    • Journal of the Korea Safety Management & Science
    • /
    • v.26 no.3
    • /
    • pp.59-70
    • /
    • 2024
  • This study aims to estimate the scope of damage impact with a real-life explosion case and a damage prediction program (ALOHA) and suggest measures to reduce risk by comparing and analyzing the results using a Probit model. After applying it to the ALOHA program, the toxicity, overpressure, and radiant heat damage of 5 tons of storage scopes between 66 to 413 meters, and the real-life case also demonstrated that most of the damage took place within 300 meters of the LPG gas station. In the Probit analysis, the damages due to radiant heat were estimated as first-degree burns (13-50%), while structural damage (0-75%) and glass window breakage (94-100%) were expected from overpressure, depending on the storage volume. After comparing the real-life case and the damage prediction program, this study concluded that the ALOHA program could be used as the scope of damage impacts is nearly the same as the actual case; it also concluded that the analysis using the Probit model could reduce risks by applying calculated results and predicting the probability of human casualties and structural damages.

Inplementation of flooding simulation in coastal area based on 3D satellite images and Web GIS

  • Jo, Myung-Hee;Park, Hyeon-Cheol;Kim, Hyoung-Sub;Choi, Yong-Ki
    • Proceedings of the KSRS Conference
    • /
    • v.1
    • /
    • pp.166-169
    • /
    • 2006
  • Our country's coast is vulnerable area to natural disaster which the repetitive damages occur every year including a loss of lives, the damage of facilities and erosion mostly except for the east coast because of a typhoon, tidal waves, sea water overflowing by topographic structure of low-lying gentle slope and shallow sea. However, as for prevention of natural disaster occurring every year, the situation is that it's centered on the restorationcentered measures and the general disaster prevention research to minimize damages at the time of disaster occurrence is insufficient. This study intendedlop t to devehe techniques possible for real time sampling of damage prediction areas on Web in order to support decision making for damage prevention and establishment of disaster prevention policy. For this, the thematic map was produced related to disaster based on high-resolution satellite picture, and the environmental DB similar to real world was constructed through topographic construction of three-dimension integrating the parts of land and the sea. In addition, the system was developed possible for the expression of damageable regions by real time grasp of dangerous regions at the time of disaster occurrence through over flowing simulation of three-dimension, and it's intended to prepare a basis to minimize damages to disaster situations through it.

  • PDF

Nationwide Inundation Analysis method for Flood and Storm Disaster Insurance Rate (풍수해보험요율 산정을 위한 전국단위 내수침수해석 방안)

  • Yoo, Jaehwan;Song, Juil;Jang, Moonyup;Kim, Hantae
    • Journal of the Society of Disaster Information
    • /
    • v.11 no.1
    • /
    • pp.55-62
    • /
    • 2015
  • This study suggested Nationwide Inundation Analysis method for Storm and Flood Damage Insurance Rate. Suggested modified Level-Pool method considers Zoning of urban plan to reflect real inundated area and limit inundation-boundary. Inundated area, as results of modified Level-Pool method, compared with inundation risk area on "storm and flood damage mitigation total plan". Simulated inundated area by modified Level-Pool method was more matched than results of traditional method. Therefore, modified Level-Pool method could be useful to analyze nationwide inundated area.