• Korean Journal of Clinical Laboratory Science
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• 제40권2호
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• pp.98-105
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• 2008

Colorectal carcinoma from various cancers is fourth ranked occurred to Korean. Due to western dietary life, this cancer has been increased continuously. Therefore, the further study will be needed to find a candidate gene involved in the development and progression of colorectal carcinoma as well as to diagnose and treatment helpfully. The purpose of this study was designed to find a carcinogenesis gene using microsatellite marker on chromosomes 7th and 20th from 30 colon cancer patients. The amplification was investigated in order of D20S97 57% (17/30), D20S101 57% (17/30), D20S119 53% (16/30), D7S483 50% (15/30), D7S495 47% (14/30), D7S498 47% (14/30). The genetic mutation pattern depends on loci of colorectal carcinoma was shown highly amplified with 3.77 from colon cancer than with 2.08 from right colorectal carcinoma (P<0.018). The genetic mutation with lymph nodes was investigated higher with 4.13 at metastasized group than with 1.93 at non-metastasized group (P<0.001). There was no difference at comparison between histological classfication and serological CEA increase as well as on genetic mutated pattern depends on disease stage. It is suggested that the amplification on chromosomes 7q and 20q determines a pivotal role from first stage to metastasis cancer and also functions as an useful marker on diagnosis and treatment of colorectal carcinoma patients as well as follow-up checkup. Recently, the diagnosis and study using genetic analyzer are necessary for efficient application. Fortunately, several university hospitals run this genetic analyzer currently so it is expected that this method makes full use of clinical application.

• Journal of the Institute of Convergence Signal Processing
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• 제12권4호
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• pp.291-297
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• 2011

In this paper, the differential quantized method and the parallel method to reduce the size of ROM in the direct digital frequency synthesizer(DDFS) is proposed And we design the DDFS by FPGA The new ROM compression method can reduce the ROM size by using the two ROM. The quantized value of sine is saved by the quantized-ROM(Q-ROM) and the differential ROM(D-ROM). Also we design the phase-to-sine converter using the phase accumulator of parallel type for generating the high frequency. So the total size of the ROM in the proposed DDFS is significantly reduced compared to the original ROM The ROM compression ratio of 67.5% is achieved by this method. Also, the power consumption is decreased according to the ROM size reduction and we can design the DDFS generating the high frequency.

• KSCE Journal of Civil and Environmental Engineering Research
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• 제28권6C호
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• pp.359-366
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• 2008

The load distribution and deformation of pile subjected to axial loads are evaluated by a load-transfer method. The emphasis is on quantifying the effect of coupled soil resistance that is closely related to the ratio of pile diameter to soil modulus $(D/E_s)$ and the ratio of total shaft resistance against total applied load $(R_s/Q)$, in rock-socketed drilled shafts using the coupled load-transfer method. The proposed analytical method that takes into account the soil coupling effect was developed using a modified Mindlin's point load solution. Through comparisons with field case studies, it was found that the proposed method in the present study estimated reasonable load transfer behavior of pile and coupling effects due to the transfer of shaft shear loading, and thus represents a significant improvement in the prediction of load deflections of drilled shafts.

• Journal of Korean Society for Quality Management
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• 제48권2호
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• pp.269-282
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• 2020

Purpose: The practical design for experiments with mixtures of q components is consisted in the four types of design points, vertex, center of edge, axial, and center points in a (q-1)-dimensional simplex space. We propose a sequential method for the successful construction of the design space in Quality by Design (QbD) by allowing the different number of replicates at the four types of design points in the practical design when the quadratic canonical polynomial model is assumed. Methods: To compare the mixture designs efficiency, fraction of design space (FDS) plot is used. We search for the practical mixture designs whose the minimal half-width of the tolerance interval per a standard deviation, which is denoted as d₂, is less than 4.5 at 0.8 fraction of the design space. They are found by adding the different number of replicates at the four types of the design points in the practical design. Results: The practical efficient mixture designs for the number of components between three and five are listed. The sequential method to establish a design space is illustrated with the two examples based on the simulated data. Conclusion: The designs with the center of edge points replications are more efficient than those with the vertex points replication. We propose the sample size of at least 23 for three components, 28 for four components, and 33 for the five components based on the list of efficient mixture designs.

• Honam Mathematical Journal
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• 제34권4호
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• pp.603-614
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• 2012

Gottlieb polynomials were introduced and investigated in 1938, and then have been cited in several articles. Very recently Khan and Akhlaq introduced and investigated Gottlieb polynomials in two and three variables to give their generating functions. Subsequently, Khan and Asif investigated the generating functions for the $q$-analogue of Gottlieb polynomials. In this sequel, by modifying Khan and Akhlaq's method, Choi presented a generalization of the Gottlieb polynomials in $m$ variables to present two generating functions of the generalized Gottlieb polynomials ${\varphi}^m_n({\cdot})$. Here, we show that many formulas regarding the Gottlieb polynomials in m variables and their reducible cases can easily be obtained by using one of two generating functions for Choi's generalization of the Gottlieb polynomials in m variables expressed in terms of well-developed Lauricella series $F^{(m)}_D[{\cdot}]$.

• ETRI Journal
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• 제32권6호
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• pp.972-975
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• 2010

In this letter, we consider the lossy coding of a non-uniform binary source based on GF(q)-quantized low-density generator matrix (LDGM) codes with check degree $d_c$=2. By quantizing the GF(q) LDGM codeword, a non-uniform binary codeword can be obtained, which is suitable for direct quantization of the non-uniform binary source. Encoding is performed by reinforced belief propagation, a variant of belief propagation. Simulation results show that the performance of our method is quite close to the theoretic rate-distortion bounds. For example, when the GF(16)-LDGM code with a rate of 0.4 and block-length of 1,500 is used to compress the non-uniform binary source with probability of 1 being 0.23, the distortion is 0.091, which is very close to the optimal theoretical value of 0.074.

• Current Optics and Photonics
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• 제4권5호
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• pp.405-410
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• 2020

A new all-optical flip-flop (AOFF) method based on the absorption nulls of an injection-locked Fabry-Perot laser diode (FP-LD) in transverse magnetic (TM) mode is proposed and experimentally demonstrated. For the set and reset operations of the AOFF, injection locking and the destructive minus of beating in transverse electric (TE) mode are used. The absorption nulls on the TM mode are modulated according to the operations, and then non-inverted (Q) and inverted (${\bar{Q}}$) outputs can be obtained simultaneously. Thanks to the use of several absorption nulls, the proposed AOFF can achieve multiple outputs with extinction ratios of more than 15 dB. Even though the experiment is demonstrated at 100 Mbit/s, the results of previous experiments using the injection of a CW holding beam imply that the operation speed can increase to 10 Gbit/s.

• Structural Engineering and Mechanics
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• 제42권3호
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• pp.313-334
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• 2012

This paper examines the problem of a penny-shaped crack in a thermoporoelastic body. On the basis of the recently developed general solutions for thermoporoelasticity, appropriate potentials are suggested and the governing equations are solved in view of the similarity to those for pure elasticity. Exact and closed form fundamental solutions are expressed in terms of elementary functions. The singularity behavior is then discussed. The present solutions are compared with those in literature and an excellent agreement is achieved. Numerical calculations are performed to show the influence of the material parameters upon the distribution of the thermoporoelastic field. Due to its ideal property, the present solution is a natural benchmark to various numerical codes and simplified analyses.

• Journal of the Korean Chemical Society
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• 제30권3호
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• pp.273-281
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• 1986

This study is focused on the correct measurement of the equations for the determination of the impedance parameters-the differential capacity of the double layer $C_d$, solution resistance $R_Q$, transfer resitance $R_i$, and adsorption pseudcapacity $C_{\phi}$/ The application of only an imaginary part of complex function of ${\omega}$ at the sinusoidal steady state indicates the following equations of total impedance: at low frequency $|Z_{LF}|=1/{\omega}_1\;C_{\phi}\;{\sqrt{1+{{\omega}_1}^2/{\omega}^2}$, at high frequency $|Z_{HF}|={\omega}_2/({\omega}_1{\omega}_3C{\phi})({\omega}^2+{{\omega}_2}^2)\;{\sqrt{{({\omega}^2+{\omega}_2{\omega}_3)}^2+{({\omega}_2{\omega}-{\omega_3{\omega})^2}}$. The values of the total impedance of cell, phase angle, and cell current that are necessary for the calculations of impedance parameters were experimentally measured from 200 to 6000Hz for the following supporting electrolytes, 0.5M $Na_2SO_4$, 1M NaCl, 19.373% sea water, 1M HCl, 1M $KNO_3$ and for $10^{-2}M$ KI and 60mM DBNA (Di-iso-Butylnitrosoamine) in these supporting electrolytes. The derived equations in this study shows that the values of impedance parameters of $C_d,\;C_{\phi},\;R_i\;and\;R_Q\;are\;15{\sim}40\;{\mu}F/cm^2,\;162{\sim}758\;{\mu}F/cm^2\;11.5{\sim}57.6\;ohm{\cdot}cm^2\;and\;0.5{\times}10^{-2}{\sim}4.1{\times}10^{-2}\;ohm{\cdot}cm^2$ respectively.

• The Transactions of the Korean Institute of Power Electronics
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• 제8권3호
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• pp.211-220
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• 2003

This paper presents an implementation of direct torque control (DTC) of Reluctance Synchronous Motor (RSM) with an efficiency optimization. The equipment circuit in Reluctance Synchronous Motor which consider with iron losses is theoretically analyzed and the optimal current ration between torque current and exiting current analytically derived to drive RSM at maximum efficiency. For RSM, torque dynamics can be maintained even with controlling the flux level because a torque is directly proportional to the stator current unlike induction motor. The experimental results are presented to validate the applicability of the proposed method. The developed control system show high efficiency features with 1.0 Kw RSM having 2.57 ratio of d/q reluctance.