• Title/Summary/Keyword: critical life events

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Factors That Decide the Job Continuity of Young Mothers (젊은 기혼여성의 출산 후 취업연속성 결정요인)

  • 김지경
    • Journal of the Korean Home Economics Association
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    • v.42 no.3
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    • pp.91-104
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    • 2004
  • This study analyzes the critical factors that decide the job continuity of married women after one of their life events, childbirth. It is based on the employment data from KLIPS(Korea Labor and Income Panel Study). Vols. 1-4, having observed 128 young mothers who gave birth to children after 1997. The analysis showed that women's employment after their maternity leave depend on whether new mother return to their previous job or not. The Following results are obtained: First, women's age, education, availability of caretakers for their children, and family income have a positive effect on the women's return to their pre-leave employers after childbirth. Second, professional or office work and the frequency of job transition before childbirth have a positive effect on women's employment in new jobs after childbirth. Third, women's age, availability of caretakers of their children, and professional or office work are critical factors that have a positive effect on women's job continuity after childbirth, whereas the frequency of job transitions has a negative effect on employment for women.

Power Prediction of Mobile Processors based on Statistical Analysis of Performance Monitoring Events (성능 모니터링 이벤트들의 통계적 분석에 기반한 모바일 프로세서의 전력 예측)

  • Yun, Hee-Sung;Lee, Sang-Jeong
    • Journal of KIISE:Computing Practices and Letters
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    • v.15 no.7
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    • pp.469-477
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    • 2009
  • In mobile systems, energy efficiency is critical to extend battery life. Therefore, power consumption should be taken into account to develop software in addition to performance, Efficient software design in power and performance is possible if accurate power prediction is accomplished during the execution of software, In this paper, power estimation model is developed using statistical analysis, The proposed model analyzes processor behavior Quantitatively using the data of performance monitoring events and power consumption collected by executing various benchmark programs, And then representative hardware events on power consumption are selected using hierarchical clustering, The power prediction model is established by regression analysis in which the selected events are independent variables and power is a response variable, The proposed model is applied to a PXA320 mobile processor based on Intel XScale architecture and shows average estimation error within 4% of the actual measured power consumption of the processor.

Regulator of Calcineurin (RCAN): Beyond Down Syndrome Critical Region

  • Lee, Sun-Kyung;Ahnn, Joohong
    • Molecules and Cells
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    • v.43 no.8
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    • pp.671-685
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    • 2020
  • The regulator of calcineurin (RCAN) was first reported as a novel gene called DSCR1, encoded in a region termed the Down syndrome critical region (DSCR) of human chromosome 21. Genome sequence comparisons across species using bioinformatics revealed three members of the RCAN gene family, RCAN1, RCAN2, and RCAN3, present in most jawed vertebrates, with one member observed in most invertebrates and fungi. RCAN is most highly expressed in brain and striated muscles, but expression has been reported in many other tissues, as well, including the heart and kidneys. Expression levels of RCAN homologs are responsive to external stressors such as reactive oxygen species, Ca2+, amyloid β, and hormonal changes and upregulated in pathological conditions, including Alzheimer's disease, cardiac hypertrophy, diabetes, and degenerative neuropathy. RCAN binding to calcineurin, a Ca2+/calmodulin-dependent phosphatase, inhibits calcineurin activity, thereby regulating different physiological events via dephosphorylation of important substrates. Novel functions of RCANs have recently emerged, indicating involvement in mitochondria homeostasis, RNA binding, circadian rhythms, obesity, and thermogenesis, some of which are calcineurin-independent. These developments suggest that besides significant contributions to DS pathologies and calcineurin regulation, RCAN is an important participant across physiological systems, suggesting it as a favorable therapeutic target.

Development and Application of a Multidimensional Suicide Prevention Program for Korean Elders by utilizing a Community Network (지역사회 네트워크를 이용한 한국노인의 다차원적 자살예방 프로그램 개발 및 적용)

  • Jo, Kae-Hwa;Kim, Yeong-Kyeong
    • Journal of Korean Academy of Nursing
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    • v.38 no.3
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    • pp.372-382
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    • 2008
  • Purpose: The purpose of this study was to develop a multidimensional suicide prevention program for Korean elders by utilizing a community network and to evaluate its effect. Methods: A non-equivalent control group pretest-posttest design was used. The subjects were recruited from two different elderly institutions located in D city and K province, Korea. Nineteen subjects in the control group received no intervention and 20 subjects in the experimental group received a multidimensional suicide prevention program. Results: There were more significant decreases in depression, suicide ideation, and increases in life satisfaction in the experimental group compared to the control group. Conclusion: According to the above results, the multidimensional suicide prevention program for Korean elders decreased stressful events like depression, and suicide ideation and increased life satisfaction through the community network. These findings suggest that this program can be used as an efficient intervention for elders in a critical situation.

A Study on Human Error Countermeasures considering Hazardous Situational Context among Organizational Factors in NPP (원전에서 조직 위험요소의 상황적 맥락을 고려한 인적오류 관리방안 제고)

  • Luo, Meiling;Kim, Sa-Kil;Lee, Yong-Hee
    • Journal of the Korean Society of Safety
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    • v.30 no.1
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    • pp.87-93
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    • 2015
  • Most incidents and accidents involved human during operating NPPs have a tendency to be structured by complicated and various organizational, individual, and environmental factors. The salient feature of the human error in NPP was extremely low frequency, extremely high complicated and extremely serious damage of human life and property. Our research team defined as 'rare human errors'. To prevent the rare human errors, the most researchers and analysts insist invariably that the root causes be made clear. The making them clear, however, is difficult because their root causes are very various and uncertain. However, These tools have limits that they do not adapt all operating situations and circumstances such as design base events. The purpose of this study is to improve the rare human error hazards consider the situational contex. Through this challenging try based on evidences to the human errors could be useful to prevent rare and critical events can occur in the future.

Mechanisms Underlying Plk1 Polo-Box Domain-Mediated Biological Processes and Their Physiological Significance

  • Lee, Kyung S.;Park, Jung-Eun;Kang, Young Hwi;Kim, Tae-Sung;Bang, Jeong K.
    • Molecules and Cells
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    • v.37 no.4
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    • pp.286-294
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    • 2014
  • Mammalian polo-like kinase 1 (Plk1) has been studied intensively as a key regulator of various cell cycle events that are critical for proper M-phase progression. The polobox domain (PBD) present in Plk1's C-terminal noncatalytic region has been shown to play a central role in targeting the N-terminal kinase domain of Plk1 to specific subcellular locations. Subsequent studies reveal that PBD binds to a phosphorylated motif generated by one of the two mechanisms - self-priming by Plk1 itself or non-self-priming by a Pro-directed kinase, such as Cdc2. Here, we comparatively review the differences in the biochemical steps of these mechanisms and discuss their physiological significance. Considering the diverse functions of Plk1 during the cell cycle, a better understanding of how the catalytic activity of Plk1 functions in concert with its cisacting PBD and how this coordinated process is intricately regulated to promote Plk1 functions will be important for providing new insights into different mechanisms underlying various Plk1-mediated biological events that occur at the multiple stages of the cell cycle.

On the study of role play using the strategic methodology: With respect to the communicative competence improvement in language acquisition period (전략적 방법을 활용한 역할극 연구: 언어습득시기의 의사소통능력 향상을 중심으로)

  • Choe, Sook-Hee;Kim, Sung-Hun
    • English Language & Literature Teaching
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    • v.11 no.1
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    • pp.203-224
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    • 2005
  • The purpose of this study is to justify the effects of role play with respect to speaking and listening functions and to provide the strategic methodology for improving English communicative competence of fifth grade primary school students. We can expand role play as a strategic teaching method to develop English learning models, so that English can be more easily acquired to the students who are in the critical language acquisition period. Strategic role play reflects the events and experiences of many kinds of people in everyday life. It is suggested that one of the best methods to improve English communicative competence in the primary classroom is through role play. Students can develop meaning for language patterns by portraying situations in which these instances in language would be used. This study proposes to facilitate English communicative ability using various student-centered role play strategies. It is concluded that the student-centered activities using strategic role play help the students to improve their English communicative competence. This is done by deriving their own creative dialogues and presenting the role play with their interests in learning English and with subsequently positive learning effects.

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Dynamic quantitative risk assessment of accidents induced by leakage on offshore platforms using DEMATEL-BN

  • Meng, Xiangkun;Chen, Guoming;Zhu, Gaogeng;Zhu, Yuan
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.11 no.1
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    • pp.22-32
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    • 2019
  • On offshore platforms, oil and gas leaks are apt to be the initial events of major accidents that may result in significant loss of life and property damage. To prevent accidents induced by leakage, it is vital to perform a case-specific and accurate risk assessment. This paper presents an integrated method of Ddynamic Qquantitative Rrisk Aassessment (DQRA)-using the Decision Making Trial and Evaluation Laboratory (DEMATEL)-Bayesian Network (BN)-for evaluation of the system vulnerabilities and prediction of the occurrence probabilities of accidents induced by leakage. In the method, three-level indicators are established to identify factors, events, and subsystems that may lead to leakage, fire, and explosion. The critical indicators that directly influence the evolution of risk are identified using DEMATEL. Then, a sequential model is developed to describe the escalation of initial events using an Event Tree (ET), which is converted into a BN to calculate the posterior probabilities of indicators. Using the newly introduced accident precursor data, the failure probabilities of safety barriers and basic factors, and the occurrence probabilities of different consequences can be updated using the BN. The proposed method overcomes the limitations of traditional methods that cannot effectively utilize the operational data of platforms. This work shows trends of accident risks over time and provides useful information for risk control of floating marine platforms.

Effects of a Nurse Presence Program on Suicide Prevention for Elders with a Chronic Disease (간호사의 함께있음 프로그램이 만성질환 노인의 자살예방에 미치는 효과)

  • Jo, Kae-Hwa
    • Journal of Korean Academy of Nursing
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    • v.37 no.7
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    • pp.1027-1038
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    • 2007
  • Purpose: The purpose of this study was to identify the effects of a nurse presence program on suicide prevention for elders with chronic disease. Method: The subjects were recruited from two different elderly institutions located in D city and K province, Korea. Twenty subjects in the control group received no intervention and nineteen subjects in the experimental group received a nurse presence program. Result: There were more significant decreases in suicide ideation, and the cortisol level and increases in life satisfaction in the experimental group compared to the control group. Conclusion: According to the above results, a nurse presence program for elders with a chronic disease decreased stressful events like suicide ideation and increased self esteem through therapeutic interaction. These findings suggest that this program can be used as an efficient independent nursing intervention for elders in a critical situation.

The development standard research for railway safety software (철도 안전 소프트웨어를 위한 개발 기준 연구)

  • Lee, Young-Jun;Kim, Jang-Yoel;Cha, Kyung-Ho;Cheon, Se-Woo;Lee, Jang-Soo;Kwon, Ki-Choon;Jung, Ui-Jin
    • Proceedings of the KSR Conference
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    • 2007.05a
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    • pp.968-973
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    • 2007
  • The systems such as the railway control system, satellite control system and nuclear power plant control system are the safety critical systems because the failure of them could lead to risk significant events. These softwares of digital systems must follow the life cycle process from the beginning of software development to guarantee their safety and reliability. The NRC(Nuclear Regulatory Commission) Reg Guide of nuclear fields, the RTCA/DO-178B standard which is used to acquire the certification for software in industrial aero field in European Union and United State, the DEF STAN 00-55 standard for the safety of electronic weapon in England, the IEC 601-1-4 for medical equipment and the IEC 62279 for railway system recommended the development life cycle. This paper introduces the development process and compares each other. Also it indicates applicable development criteria for the software of systems related to railway fields and describes the detailed procedure of development criteria. We describe the procedure to make the software development criteria in nuclear filed. For the software development related to railways, the process from plan phase to maintenance phase must be satisfied. The safety and reliability is guaranteed through these standards.

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