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A retrospective study of 16 cats with intermediate- to high-grade alimentary lymphoma

  • Kwak, Dong-Hyuk;Cho, Mun-Ju;Park, Hyung-Jin;Song, Kun-Ho;Seo, Kyoung Won
    • Korean Journal of Veterinary Research
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    • v.61 no.1
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    • pp.8.1-8.10
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    • 2021
  • The purpose of this retrospective study was to describe cases of feline intermediateto high-grade alimentary lymphoma regarding signalment, clinical presentation, laboratory findings, response to therapy (modified 25-week University of Wisconsin-Madison [UW-25] vs. COP [cyclophosphamide, vincristine, prednisone]), toxicosis, and outcomes and to identify prognostic factors. Sixteen cats were treated with chemotherapy protocols. Response rates and survival did not differ statistically between the two protocols. The progression-free interval (PFI) and median survival time (MST) in cats achieving a response to therapy were longer than in those with no response [NR] (complete remission [CR] vs. partial remission [PR] vs. NR; PFI, 124 vs. 49 vs. 12 days, p < 0.001; MST, 361 vs. 118 vs. 16 days, p < 0.001). Clinical stage was another prognostic factor for PFI and MST. The PFI and MST in cats in stage I were longer than in those in other stages (PFI, 107 days vs. 30 days; MST, 193 days vs. 54 days). Hematologic and gastrointestinal toxicosis was mostly low grade. In comparing the modified UW-25 protocol with the COP protocol, there was not much difference in the number of neutropenic episodes and grade levels.

A Study on Comparative Analysis of Energy Performance of Hybrid Heat Pump Systems Using Ground Heat Source and Water Heat Source (지열원과 수열원을 이용한 하이브리드 히트펌프 시스템의 에너지 성능 비교 분석 연구)

  • Park, Sihun;Kim, Jonghyun;Min, Joonki
    • Journal of the Korean Society for Geothermal and Hydrothermal Energy
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    • v.17 no.4
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    • pp.59-67
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    • 2021
  • In this study, the performance of the single heat source system and the hybrid system was comparatively analyzed. Case 1 is a ground heat source system, and Case 2 is a water heat source system. Case 3, a hybrid system, reduced the capacity of the ground heat source and applied a water heat source as an auxiliary heat source, and Case 4 was composed of a system that applied a water heat source as an auxiliary heat source to the ground heat source system. As a result of the simulation, in case 3, energy consumption was reduced by up to 2.67% compared to ground sources for cooling. In Case 4, COP was improved by up to 10.02% compared to ground sources during cooling, and EST was calculated to be 2.42℃ lower. During heating, 0.83% was improved compared to the water heat source. At this time, the EST was calculated to be 2.25℃ higher than the water heat source.

Comparison of Postural Control Ability according to the Various Video Contents during Action Observations

  • Goo, Bon Wook;Lee, Mi Young
    • The Journal of Korean Physical Therapy
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    • v.33 no.1
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    • pp.16-20
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    • 2021
  • Purpose: This study examined the effects of the type of video contents used for action observations on the ability to control posture. Methods: The participants were 48 healthy adults. The two hands of the participants were crossed on both shoulders, and the other foot was placed in a straight line in front of the target to allow them to watch a video of the monitor. The videos were presented in random order with three video contents (natural, stable balance posture, and unstable balance posture) consisting of 30 seconds each. A 15-second resting time was given between each video. During action observation using various video content forms, the posture control ability was measured using a TekScan MetScan® system. Results: The results revealed statistically significant differences in the area of movement and the distance by COP and distance by the type of action-observation videos, and the distance by the anteroposterior and mediolateral sides (p<0.05). The stable balance posture and unstable balance posture video showed significant differences in the distance by the COP, anteroposterior, and mediolateral distance. (p<0.05) Conclusion: This study suggests that choosing the contents of the videos is important during action-observation training, and action-observation training can help improve postural control.

The Feasibility Study of Sit-to-stand and Stand-to-sit Assistive Chair for Elderly

  • Seonggwang Yu;Seungmuk Lee;Minsoo Kim;Dae-Sung Park
    • Physical Therapy Rehabilitation Science
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    • v.11 no.4
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    • pp.591-597
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    • 2022
  • Objective: The sitting and standing are motions that correspond to the previous stage of rehabilitation to go to walking for daily life. The purpose of this study was to measure task times, path length of the center of pressure (COP) and activity on the vastus femoris muscle using surface electromyography (EMG) when standing up and sitting down. Design: One group cross-sectional design Methods: Fifteen elderly subjects (8 male, 7 female) participated. All subjects were tested three times according to four assist levels (non-assist, lower, middle, and maximal assist) using adjusts the length of spring at sit-to-stand and stand to sit on a chair. The task duration, and COP path length were recorded for the balance function on the Nintendo Wii fit board. The activity of the rectus femoris muscle was recorded on both legs using surface EMG. Results: The results showed that the task duration of the sit-to-stand and stand-to-sit were significantly increased compared to without assist (p<.05). The activation of the rectus femoris muscle more significantly decreased compared to without assistance at standing or sitting (p<.05). Conclusions: The assistive chair showed less quadriceps muscle activation during sitting and standing compared to without assistance. We suggest that our assist-standing chair can help with activities of daily living such as standing up and sitting down movements adjusting the spring length for control assist level by safely.

Cluster analysis of city-level carbon mitigation in South Korea

  • Zhuo Li
    • Journal of the Korea Society of Computer and Information
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    • v.28 no.7
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    • pp.189-198
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    • 2023
  • The phenomenon of climate change is deteriorating which increased heatwaves, typhoons and heavy snowfalls in recent years. Followed by the 25th United nations framework convention on climate change(COP25), the world countries have achieved a consensus on achieving carbon neutrality. City plays a crucial role in achieving carbon mitigation as well as economic development. Considering economic and environmental factors, we selected 63 cities in South Korea to analyze carbon emission situation by Elbow method and K-means clustering algorithm. The results reflected that cities in South Korea can be categorized into 6 clusters, which are technology-intensive cities, light-manufacturing intensive cities, central-innovation intensive cities, heavy-manufacturing intensive cities, service-intensive cities, rural and household-intensive cities. Specific suggestions are provided to improve city-level carbon mitigation development.

A Methodology of Optimal Design for Solar Heating and Cooling System Using Simulation Tool

  • Lee, Dongkyu;Nam, Hyunmin;Lee, Byoungdoo
    • International conference on construction engineering and project management
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    • 2015.10a
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    • pp.540-543
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    • 2015
  • Solar energy is one of the most important alternative energy sources which have been shown to meet high levels of heating and cooling demands in buildings. However, the efficiencies to satisfy these demands using solar energy significantly vary based on the characteristics of individual building. Therefore, this paper is focused on developing the methodology which can help to design optimal solar system for heating and cooling to be in cooperated within the existing buildings according to their load profiles. This research has established the Solar Heating and Cooling (SHC) system which is composed of collectors, absorption chiller, boiler and heat storage tank. Each component of SHC system is analyzed and made by means of Modelica Language and Pistache tool is verified the results. Sequential approximate optimization (SAO) and meta-models determined to 15 design parameters to optimize SHC system. Finally, total coefficient of performance (COP) of the entire SHC system is improved approximately 7.3% points compared to total COP of the base model of the SHC system.

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Simulink Analysis for the Optimal Efficiency of Air-Source and Ground-Source Heat Pumps (공기 열원 및 지열원 히트펌프 난방의 적정 효율 계산을 위한 시뮬링크 분석)

  • Seung Ik Shin;Jinkyun Cho;Joo Hyun Moon
    • Journal of ILASS-Korea
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    • v.29 no.3
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    • pp.124-133
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    • 2024
  • Heat pumps play a crucial role in achieving the 2050 Net-Zero targets in many countries worldwide. This study addresses this issue by modifying simulation conditions and selecting relevant cases to determine optimal COP conditions using Simulink. By analyzing the efficiency of heat pump heating, utilizing Simulink models provided by MATLAB, and evaluating economic feasibility, we aim to identify the key factors influencing heat pump performance, including the heat source type, refrigerant, heating set temperature, and piping. Our goal is to establish optimal conditions for maximizing the efficiency of these eco-friendly systems while considering economic factors. In this study, it was confirmed that the heat exchanger flow arrangement of the air-source heat pump using R407c was set to cross-flow, and the diameter of the heat exchanger inner tube was set to 0.95 times the existing size, which was found to be optimal for maximizing efficiency. The COP was approximately 4.07 under these conditions.

Analysis of a Cross-cutting Issue, 'Access to Genetic Resources and Benefit-sharing' of the Conference of the Parties to the Convention on Biological Diversity (생물다양성협약 당사국회의의 핵심논제인 '유전자원에 대한 접근과 이익의 공유'에 관한 고찰)

  • Park, Yong-Ha
    • Journal of Environmental Policy
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    • v.6 no.1
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    • pp.41-60
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    • 2007
  • Attempts were made to define the elements of debates, impact of decisions of the Access to Genetic Resources and Benefit-sharing(ABS) of the Conference of the Parties(COP) to the Convention on Biological Diversity(CBD) In Korea. Providing policy suggestions to cope with ABS, a cross-cutting issue of the meetings of the COP, was also undertaken. Meetings concerning ABS deal with several key matters such as an international regime, which is a legally binding implementation tool of the Bonn Guidelines, an international certificate of genetic resources' origin/source/legal provenance, and disclosure of origin of genetic resources, compliance measures with prior informed consent of the Contracting Parties providing such resources and with mutually agreed terms on which access was granted. Developing countries, rich in biodiversity and genetic resources, use the CBD as a major tool to maximize their national profits. They demand for national sovereign rights for the genetic resources and indigenous communities providing associated traditional knowledge. At the meetings of the COP, in addition, they requested that developed countries should transfer technologies and provide a financial mechanism for resource conservation to them. On the contrary, the developed countries argue that facilitating access to genetic resources is essential for scientific research and development, and that both Intellectual Property Rights and biotechnology using genetic resources should be protected to maximize their national benefits. Decisions of the COP concerning the Bonn Guidelines and compliance measures with ABS will affect on various socioeconomic fields of Korea, a country which is short of genetic resources. Especially, the importation of genetic resources and land development which might damage genetic resources will be limited seriously. Consequently, overall expenses will increase for the securing genetic resources from the foreign countries and developing biotechnology for conservation and sustainable uses of genetic resources. To minimize the adverse impacts, we endeavor to establish our clear standpoint and to lead the international trends, which are favorable for us. In order to achieve these objectives, government needs i) to proceed researches to lead the international ABS debates actively and to prepare the expected decisions of the future meetings of the COP, ii) to establish a national implementation plan to cope with the ABS and its related decisions, iii) to examine and improve the efficiencies of the national implementation plan with a proper monitoring system, and iv) cope with the other international meetings including the meetings of Trade Related Intellectual Properly Rights and International Treaty on Plant Genetic Resources for Food and Agriculture actively.

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An Experimental Study on Radiation/Convection Hybrid Air-Conditioner (복사-대류 겸용 하이브리드 냉방기에 대한 실험 연구)

  • Kim, Nae-Hyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.6
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    • pp.288-296
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    • 2019
  • Radiation cooling has used ceilings or floors as cooling surfaces. In such cases, to avoid moisture condensation on the surface, the surface temperature needs be higher than the dew point temperature or an additional dehumidifier is added. In this study, with a goal for residential application, intentional moisture condensation on the cooling surface was attempted, which increased the cooling capacity and improved the indoor comfortness. This method included two separate refrigeration cycles - convection-type dehumidifying cycle and the panel cooling cycle. Test results on the panel cooling cycle showed that, at the standard outdoor ($35^{\circ}C/24^{\circ}C$) and indoor ($27^{\circ}C/19.5^{\circ}C$) condition, the refrigerant flow rate was 8.8 kg/h, condensation temperature was $51^{\circ}C$, evaporation temperature was $8.8^{\circ}C$, cooling capacity was 376 W and COP was 1.75. Furthermore, the panel temperature was uniform within $1^{\circ}C$ (between $13^{\circ}C$ and $14^{\circ}C$). As the relative humidity decreased, the cooling capacity decreased. However, the power consumption remained approximately constant. In the convection-type dehumidification cycle, the refrigerant flow rate was 21.1 kg/h, condensation temperature was $61^{\circ}C$, evaporation temperature was $5.0^{\circ}C$, cooling capacity was 949 W and COP was 2.11 at the standard air condition. When both the radiation panel cooling and the dehumidification cycle operated simultaneously, the cooling capacity of the radiation panel cycle was 333 W and that of the dehumidification cycle was 894 W, and the COP was 1.89. As the fan flow rate decreased, both the cooling capacity of the radiation panel and the dehumidification cycle decreased, with that of the dehumidification cycle decreasing at a higher rate. Finally, a possible control logic depending on the change of the cooling load was proposed based on the results of the present study.

Characteristics of Ondol Heating Load for the Determination of Heat Pump Power (열펌프 시스템의 규모 결정을 위한 온돌난방부하 특성)

  • 노정근;백은기;송현갑
    • Journal of Biosystems Engineering
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    • v.28 no.3
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    • pp.217-224
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    • 2003
  • To find out heating load and to determine the power of heat pump compressor for the Ondol room heating the COP of heat pump, the variation of Ondol room air temperature, the variation of ambient temperature and power consumption of heat pump are analyzed. The results from this study were summarized as follows: 1. The COP of the heat pump in close loop decreased as the ambient air temperature. The COP was 2.26 when the temperature difference of condenser was $20\pm3^{\circ}C$. 2. The Ondol surface temperature was $25\pm3^{\circ}C$ when the hot water of $40^{\circ}C$ was supplied from hot water storage tank to the Ondol and the temperature difference between the Ondol surface and the room air temperature was $7~8^{\circ}C$. 3. The ratio of thermal conduction heating load to total heating load in Ondol heating space was found to be 83% and ratio of ventilation heating load was 17%. Therefore, the thermal conduction heating load was confirmod to be a major heating load in Ondol heating space. 4. In case of the ambient temperature of $3.2^{\circ}C$, the efficiency of heat exchange of Ondol heating system was 85%. 5. The heating load per Ondol heating surface area and volume of Ondol room space were theoretically analyzed. In case of the room temperature of $20^{\circ}C$ and the ambient temperature of $-3.2~3.8^{\circ}C$, the heating load per Ondol surface area was 115.8~167.6kJ/h ㆍ㎥ and per Ondol mom space volume was 50.2~72.7kJ/h ㆍ㎥. 6. The compressor power of heat pump fur the Ondol room heating could be determined with the heating load analyzed in this study In case of the Ondol room air temperature of 17~2$0^{\circ}C$ and the ambient temperature of -5~3.8$^{\circ}C$, the compressor power of heat pump per Ondol surface area was analyzed to be $2.3\times10^{-2}psm^2$, and per volume of Ondol room space $1.0\times10^{-2}1.4\times10^{-2}ps/m^2$ps.