• Journal of Sasang Constitutional Medicine
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• v.12 no.1
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• pp.10-23
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• 2000

Four-constitutional theory proposed by Dr. Lee, Je-ma has been evolve for last 100years by his followers. One of the major progresses was the emergence of constitutional acupuncture proposed by Dr. Kwan Doh-won. Constitutional acupuncture included the new pulse diagnostic method to determine the body type, pulse diagrams and corresponding acupuncture method called five element acupuncture in which five-element points in 12 meridian channels are used. Dr. Sa-ahm proposed five-element acupuncture three and a half hundred years age. Conjunction of Dr Lee's theory to Dr. Kwan proposed eight constitutions with eight pulse diagrams. He also adopted eight acupuncture prescriptions out of twenty-four Sa-ahm's acupuncture prescriptions. The author, Dr. Yom Tae-hwa, proposed more inclusive theory of 24 constitutions with 24 diagnostic pulse diagrams in Las Vegas International Acupuncture Convention in 1986. This article reviews history of constitutional medicine briefly. Each step of theoretical evolution from four-constitutional theory to twenty-four-constitutional theory is explained. By understanding the theoretical connection between twelve meridian channels based on five-element theory and four-constitutional theory in the article, one will easily accept the emergence of twelve of twenty four constitutional theory. Next, the article is focused on four subcategories under Sao-Yin constitution, which are one-sixth of 24 constitution. in this section classification, pulse diagnostic method, pulse diagram acupuncture prescriptions and herbal prescriptions are explained in detail. Then, clinical trial reports of acupuncture treatment and/or herbal formulas for such constitutions are attached for the rest part of the article. the purpose of this paper is to present the new hypothesis with the result of preliminary clinical trial hoping that additional clinical reports from other practitioners in this field triggers well-designed clinical study in future.

• The Korean Journal of Mycology
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• v.17 no.3
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• pp.119-123
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• 1989

Interorder heterokaryons were obtained by polyethylene glycol induced fusion of protoplasts from auxotrophic mutants of Pleurotus ostreatus in agaricales and Ganoderma applanaturm in aphyllophorales. When transferred to MMM plates, all fusion colonies exhibited an extremely growth rate. During three times subcultivation on MCM the growth rate of fusants showed faster little by little. Seventy-five % fusion products of potoplasts showed mixed morphologies between those of P. ostreatus and G. applannatum in the first subcultivation on MCM and MGM. The phenotype of these fusants changed similar those of P. osteatus type after three times subcultivation on MCM. However, phenotype of 25% stable strains did not change on subcultivation. Hyphae of all fusion products did not form true clamp connection. All these types did not produce primordia. A comparrison of interorder somatic hybrids was made using isozyme analysis of esterase, malate dehydrogenase and peroxidase. In most cases the enzyme patterns of G. applanatum were not distinct, however, fusant showed non-parental bands.

• Journal of The Korean Association For Science Education
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• v.36 no.2
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• pp.279-293
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• 2016

The purpose of this study was to analyze the effect of infographic instruction to promote the use of the scientific model in the 'lens' unit of elementary science textbooks. The participants were $6^{th}$ grade students(n=53) of G elementary school in G city, Gyeongsangnam-do. For this study, the lesson plan of the 'lens' unit consisted of three steps as investigation of students' prior concept about the lens, scientific model construction activity, and infographic construction activity. We then analyzed the results of this study from three perspectives: the scientific concept, scientific model, and infographic. Before the lesson, students focused on the external shape and material of the lens in prior concept of it. However, after the scientific model construction activity and infographic construction activity, students' scientific concept about the lens improved in the categories of features of lens, features of glasses, light path, and applications of the lens. In terms of the scientific model, use of type and frequency of scientific model increased more in the infographic construction activity than the scientific construction model activity. Also, in terms of infographic, the two infographic types as function based infographic and connection based infographic used more than non-infographic in the infographic construction activity. Also, the frequency of Gestal theory's visual perception increased more in the infographic construction activity than the scientific model construction activity.

• The Journal of Korean Academy of Prosthodontics
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• v.42 no.3
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• pp.307-326
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• 2004

Statement of problem. The long-term success of implants is the development of a stable direct connection between bone and implant surface, which must be structural and functional. To improve a direct implant fixation to the bone, various strategies have been developed focusing on the surface of materials. Among them, altering the surface properties can modify cellular responses such as cell adhesion, cell motility and bone deposition. Purpose. This study was to evaluate the cellular behaviors on the surface-modified titanium by morphological observation, cellular proliferation and differentiation. Material and methods. Specimens were divided into five groups, depending on their surface treatment: electropolishing(EP) anoclizing(AN), machining(MA), blasting with hydroxyapatite particle(RBM) and electrical discharge machining(EDM). Physicochemical properties and microstructures of the specimens were examined and the responses of osteoblast-like cells were investigated. The microtopography of specimens was observed by scanning electron microscopy(SEM). Surface roughness was measured by a three-dimensional roughness measuring system. The microstructure was analyzed by X-ray diffractometer(XRD) and scanning auger electron microscopy(AES). To evaluate cellular responses to modified titanium surfaces, osteoblasts isolated from neonatal rat were cultured. The cellular morphology and total protein amounts of osteoblast-like cell were taken as the marker for cellular proliferation, while the expression of alkaline phosphatase was used as the early differentiation marker for osteoblast. In addition, the type I collagen production was determined to be a reliable indicator of bone matrix synthesis. Results. 1. Each prepared specimen showed specific microtopography at SEM examination. The RBM group had a rough and irregular pattern with reticulated appearance. The EDM-treated surface had evident cracks and was heterogeneous consisting of broad sheet or plate with smooth edges and clusters of small grains, deep pores or craters. 2. Surface roughness values were, from the lowest to the highest, electropolished group, anodized group, machined group, RBM group and EDM group. 3. All groups showed amorphous structures. Especially anodized group was found to have increased surface oxide thickness and EDM group had titaniumcarbide(TiC) structure. 4. Cells on electropolished, anodized and machined surfaces developed flattened cell shape and cells on RBM appeared spherical and EDM showed both. After 14 days, the cells cultured from all groups were formed to be confluent and exhibited multilayer proliferation, often overlapped or stratified. 5. Total protein amounts were formed to be quite similar among all the group at 48 hours. At 14 days, the electropolished group and the anodized group induced more total protein amount than the RBM group(P<.05). 6. There was no significant difference among five groups for alkaline phosphatase(ALP) activity at 48 hours. The AN group showed significantly higher ALP activity than any other groups at 14 days(P<.05). 7. All the groups showed similar collagen synthesis except the EDM group. The amount of collagen on the electropolished and anodized surfaces were higher than that on the EDM surface(P<.05).

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.3
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• pp.269-281
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• 2014

In this paper, a systematic design of a low phase noise voltage-tuned dielectric resonator oscillator(VTDRO) using loop group delay is proposed. Designed VTDRO is closed-loop type and consists of a cascade connection of a resonator, phase shifter, and amplifier. Firstly, a reference VTDRO is fabricated and its phase noise and electrical frequency tuning range are measured. Both the phase noise and electrical frequency tuning range depend on the loop group delay. Then, a required value of loop group delay for a new VTDRO with a low phase noise can be systematically computed. In addition, its phase noise and electrical frequency tuning range can be theoretically estimated using those obtained from the measurement of the reference VTDRO. When the loop group delay increases, the phase noise decreases and the electrical frequency tuning range also decreases. The former predominantly depends on the resonator structure. Therefore we propose a systematic design procedure of a resonator with high group delay characteristics. The measured loop group delay of the new VTDRO is about 700 nsec. The measured phase noise of the new VTDRO show a state-of-the-art performance of 154.5 dBc/Hz at 100 kHz frequency offset and electrical frequency tuning range of 448 kHz for a voltage change of 0~10V. The oscillation power is about 4.39 dBm.

• Korean journal of communication and information
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• v.77
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• pp.36-72
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• 2016

Comprehensive Cable TV Channels(CCCs) has been established as a political product around 5 years ago, and it's influence and position on the broadcasting field are keep increasing. CCC's stabilization is based on flooding the market with journalism. The repeating news and current affairs programs are appearing constantly in the afternoon which is CCC's primetime. The current affairs talk shows are a product of CCC's representative program type and it leads unique CCC style journalism. The guests of the current affairs talk show leading the program with critiques(comments) and discussions about political issues. The purpose of this study is to explore how these guests of the current affairs talk shows conceptually positioned as political mediating elites and same time to explore the television political landscape through the representative current affairs talk shows from TV chosun, Channel A, MBN, JTBC which are present by these political elites. This study wants to find out about that television political effects from CCCs which exemplified into certain directions by these political mediating elites saying their political biases and expresses their feelings drastically that causes high ratings and brings people's attention. The guests who called political mediating elites in this study are mostly considered to be extreme rightist, conservatives, conservative-centrist and they have close relationship with certain political party or political group. The political mediating elites gain the popularities and have great influence on the public from performing the television politics through CCCs' current affairs talk shows and use that to make political exchange connections with political groups. Therefore this study wants to point out that CCCs' current affairs talk shows are situated in political rally, exchange connection, so current affairs talk shows are existing only for political battle field.

• Journal of Bio-Environment Control
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• v.26 no.4
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• pp.402-410
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• 2017

The effect of the steel pipe member joint on the design performance of a plastic multi-span greenhouse was analysed through the comparing full-scale experiment and numerical analysis. The design performance of the greenhouse is generally evaluated through numerical analysis, but it is rare to consider the characteristics of the connections or joints of the members. In this study, the effect of the column-gutter beam-rafter-wind break wall joint on the design performance of the whole structure of a plastic multi-span greenhouse was analysed. The numerical results with assuming that the member joint are rigid condition were compared with the full-scale load test results using member joints used in the field. The stiffness of the entire structure was compared using the load-displacement relationship and the change of the load sharing ratio that the main members such as column, rafters, and wind break wall was analysed. The results of the load test were about 40% larger than the numerical result and the member stress was more than twice as large as those of the loaded columns. In order to increase the reliability of the design performance of the greenhouse, it is necessary to develop a numerical analysis model which can consider the characteristics of various joints.

• Molecular & Cellular Toxicology
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• v.5 no.4
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• pp.298-303
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• 2009

(-)-Epigallocatechin-3-gallate (EGCG), a major flavonoid in green tea has multiple health benefits including chemoprevention, anti-inflammatory, anti-diabetic, and anti-obesity effects. In connection with these effects, EGCG can be a candidate to help the treatment of metabolic diseases. Metformin is a widely used anti-diabetic drug regulating cellular energy homeostasis via AMP-activated protein kinase (AMPK) activation. Therefore, the combination of metformin with EGCG may have additive or synergistic effects on treatment of type 2 diabetes. Nevertheless, there is no report for the pharmacokinetic and/or pharmacodynamic interaction of EGCG with metformin. Here, we evaluated the pharmacokinetic and pharmacodynamic interaction between metformin and EGCG in rats. Pharmacokinetics parameters of metformin were measured after oral administration of metformin in rats pre-treated with EGCG (10 mg/kg) or saline for 7 days. The results showed that there is no significant difference in pharmacokinetic parameters between saline control and EGCG-treated group. In addition, the hepatic AMPK activation by metformin in EGCG-treated rats was also similar to the control. The lack of additive effects of EGCG on AMPK activation or intracellular uptake of metformin was also evaluated in cells in the presence or absence of EGCG. Treatment of HepG2 cells with EGCG inhibited the metformin-induced AMPK activation. Combined results suggested that EGCG has no effect on the pharmacokinetics of metformin but may contribute to metformin action.

• The Korean Journal of Nuclear Medicine Technology
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• v.21 no.2
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• pp.13-27
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• 2017

Purpose In the procedure of domestic medical radioactive self-disposal, there are many requests of supplementation and difficulties on the screening process. In this regard, presentation of basic guideline will improve the work processing efficiency of medical institution radioactive waste. From 2015 to 2016, We reviewed and compared a supplementary requests of domestic fifteen medical institution radioactive self-disposal Plan & Procedure manual. In connection with this, we derive the details of the radioactive waste document based on the relative regulation of nuclear safety Act. The representative supplementary requests of Korea Institute of Nuclear Safety are disposal method of non-flammability radioactive waste, storage method of scheduled self-disposal waste, the legitimacy of self-disposal and pre-treatment of self-disposal, reference radioactivity of disused filter and output of storage period, attachment the evidential matter of measurement efficiency when using a gamma counter. Through establishing a medical radioactive waste guideline, we can clearly suggest a classification standard of radioactive nuclide and the type of occurrence. As a result, we can confirm the reduction of examination processing period while preparing a self-disposal document and there is no spending expenses for business agency. Also, the storage efficiency of facility will better and reduce the economic expenses. On the basis of this guideline, we will expect a contribution to the improvement of work efficiency for officials who has a working-level difficulty of radioactive waste self-disposal.

• The Journal of Korean Academy of Prosthodontics
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• v.54 no.2
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• pp.103-109
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• 2016

Purpose: This study is to evaluate the clinical significance of implantation with simultaneous bone graft by comparing the marginal bone loss around maxillary anterior implants with or without bone graft. Materials and methods: Patients treated with implant-retained restorations on maxillary anterior region at Implant Center, Dental Hospital, Wonkwang University between June 2011 and May 2014 were included in this study. Date of implant placement, implant diameter, implant length, implant-abutment connection type and whether the bone graft was done were investigated. The patient's periapical radiographs taken immediately after implantation and at the most recent visit were compared. Marginal bone loss was measured using Emago advanced v5.6 program (Oral diagnostic systems, Amsterdam, Netherlands). Statistical analysis was done in independent t-test by using SPSS 22.0 program. Results: As a result of observing on 83 implants (without bone graft: 44, with bone graft: 39) of 52 patients for 6 - 45 months (average: 18.4 months), implants without bone graft showed $1.42{\pm}0.42mm$, implants with bone graft showed $1.28{\pm}0.45mm$ of marginal bone loss. Conclusion: In limitations of this study, implants with simultaneous bone graft had significantly less marginal bone loss than implants without bone graft.