• Applied Chemistry for Engineering
• /
• v.23 no.6
• /
• pp.577-582
• /
• 2012

In this work, vibrational circular dichroism (VCD) technique was applied for the determination of %EE of chiral compounds. It may provide an easy way to determine the %EE with a proper accuracy within 2% error ranges as well as the absolute configuration of enantiomers. We demonstrated herein a flow cell VCD (FT-VCD) technique for time-dependent %EE measurements. The simultaneous monitoring of the mole fraction and %EE for two chiral species (epichlorohydrin and glycidol mixture) in the mixture was shown to be successful without any further separation steps. Thus, we demonstrate that FT-VCD is an appropriate analytical tool to monitor the kinetics of reactions involving chiral molecules. FT-VCD also provides a convenient nondestructive approach for the time dependent determination of the optical purity of individual components in a reaction mixture containing chiral molecules.

• Proceedings of the IEEK Conference
• /
• 2002.07b
• /
• pp.830-833
• /
• 2002

To solve the internal security problem such as human error and bad faith, the automation of computer system management is significant. For this purpose, we focus attention in the automation of Mail Delivery Service. Today, requirement for reliable mail delivery system becomes larger and larger. However, existing systems are too strict about their configuration. Hence, we propose the method based on Reinforcement Learning (RL) to achieve proper MX record ordering. A measure on validity of the design of system, such as network topology number of servers and so on, is also obtained as side benefit. In order to verify the usability of the presented method, we did on a small model of mail delivery system. As a result, we show that RL is available for determination of the proper MX record ordering. Additionally, we suggest that it is also available for comparing validity of setting of MTA and the network design.

• Proceedings of the Computational Structural Engineering Institute Conference
• /
• 1998.04a
• /
• pp.272-279
• /
• 1998

The purpose of this study is to show how to gain the morphology of the Hybrid Spatial Structures and to get the geometrical data such as node coordinates, member relationships and graphic images. To form spatial structures, we have developed morphological aspects of general spatial structures, programming process and techniques. Structural design has many processes. Especially, it is very important to consider the determination of structural configuration. Regular Hybrid Spatial Structures have complex configuration, so we need to make use of automated computer process to determine structural shape in Hybrid Spatial Structures. We have applied morphological aspects to double layer plate, single layer dome, double layer dome and tensegrity structure.

• Biomolecules & Therapeutics
• /
• v.31 no.5
• /
• pp.566-572
• /
• 2023

A chiral derivatization strategy with phenylglycine methyl ester (PGME) was employed to develop a straightforward method to determine the absolute configurations of N,N-dimethyl amino acids. The PGME derivatives were analyzed using liquid chromatography-mass spectrometry to identify the absolute configurations of various N,N-dimethyl amino acids based on their elution time and order. The established method was applied to assign the absolute configuration of the N,N-dimethyl phenylalanine in sanjoinine A (4), a cyclopeptide alkaloid isolated from Zizyphi Spinosi Semen widely used as herbal medicine for insomnia. Sanjoinine A displayed production of nitric oxide (NO) in LPS-activated RAW 264.7 cells.

• IE interfaces
• /
• v.11 no.3
• /
• pp.23-40
• /
• 1998

In this paper, a method to determine the optimal configuration of operating policies in an integrated-automated manufacturing system using the Taguchi method and computer simulation experiments is presented. An integrated-automated manufacturing system called direct-input-output manufacturing system(DIOMS) is described. We only consider the operational aspect of the DIOMS. Four operating policies including input sequencing control, dispatching rule for the storage/retrieval(S/R) machine, machine center-based part type selection rule, and storage assignment policy are treated as design factors. The number of machine centers, the number of part types, demand rate, processing time and the rate of each part type, vertical and horizontal speed of the S/R machine, and the size of a local buffer in the machine centers are considered as noise factors in generating various manufacturing system environment. For the performance characteristics, mean flow time and throughput are adopted. A robust design experiment with inner and outer orthogonal arrays are conducted by computer simulation, and an optimal configuration of operating policies is presented which consists of a combination of the level of each design factor. The validity of the optimal configurations is investigated by comparing their signal-to-noise ratios with those obtained with full factorial designs.

• Journal of Institute of Control, Robotics and Systems
• /
• v.5 no.5
• /
• pp.614-621
• /
• 1999

In this paper, the analytical appproaches are presented for jointly determining the profit-miximizing configuration of the fault-tolerance real time modular cell manufacturing system. The transient(time-dependent) analysis of Markovian models is firstly applied to modular cell manufacturing system from a performability viewpoint whose modeling advantage lies in its ability to express the performance that truly matters - the user's perception of it - as well as various performance measures compositely in the context of application. The modular cells are modeled with hybrid decomposition method and then availability measures such as instantaneous availability, interval availability, expected cumulative operational time are evaluated as special cases of performability. In addition to this evaluation, sensitivity analysis of the entire manufacturing system as well as each machining cell is performed, from which the time of a major repair policy and the optimal configuration among the alternative configurations of the system can be determined. Secondly, the recovery policies from the machine failures by computing the minimal number of redundant machines and also from the task failures by computing the minimum number of tasks equipped with detection schemes of task failure and reworked upon failure detection, to meet the timing requirements are optimized. Some numerical examples are presented to demonstrate the effectiveness of the work.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.31 no.1 s.256
• /
• pp.43-49
• /
• 2007

A new electric coil design methodology using the notion of topology optimization is developed. The specific design problem in consideration is to find optimal coil configuration that maximizes the Lorentz force under given magnetic field. Topology optimization is usually formulated using the finite element method, but the novel feature of this method is that no such partial differential equation solver is employed during the whole optimization process. The proposed methodology allows the determination of not only coil shape but also the number of coil turns which is not possible to determine by any existing topology optimization concept and to perform single coil strand identification algorithm. The specific applications are made in the design of two-dimensional fine-pattern focusing coils of an optical pickup actuator. In this method, the concept of equivalent magnetizing current is utilized to calculate the Lorentz force, and the optimal coil configuration is obtained without any initial layout. The method is capable of generating the location and shape of turns of coil. To confirm the effectiveness of the proposed method in optical pickup applications, design problems involving multipolar permanent magnets are considered.

• Proceedings of the Computational Structural Engineering Institute Conference
• /
• 1997.04a
• /
• pp.152-159
• /
• 1997

This unit - structure of truss stabilized by cable tension is composed of four truss member adding to a central post and eight cables, and is connected by hinge joints and is stabilized by cable tension. As this unit - structures itself is a statically closed and stabilize system individually, it can be employed to assemble a structure with a variety of configuration. In this paper, for determination the shape of the unit - structure of truss stabilized by the cable, characteristics such as the stabilized range of the various geometrical parameter about unit system and the relation of the best governing paramter is demonstrated, and the relation of the results is compared in the range for the stabilization of unit-structure.

• Journal of the Korean Magnetic Resonance Society
• /
• v.27 no.4
• /
• pp.35-41
• /
• 2023

From a marine sponge Dysidea species, four new furanosesquiterterpenoids were isolated and characterized. Their structural elucidation was achieved through an extensive analysis employing NMR, MS data, and DFT method. Notably, all compounds shared as identical molecular formula. Compound 2 was identified as a derivative of compound 1, while compounds 3 and 4 exhibited an identical planar structure. Determination of the configurations of chiral centers in compounds 1 and 2 involved a comparative analysis between measured and calculated ECD spectra, along with the application of DP4+ probability analysis. Distinctly, the configurations of isomers 3 and 4 were established by scrutinizing proton chemical shifts based on the NOE correlation.

• 제어로봇시스템학회:학술대회논문집
• /
• 1997.10a
• /
• pp.1338-1341
• /
• 1997

In this paper, we propose angular rate computation algorithm using GPS carrier phase. A direct angylar rate masurement has not previously been available form GRS, although its availability is highly desirable for use in state feedback control. So we propose angular rate computationalgorithm which derive angular rate from the velocity of differentiated carrier phase og GPS. The proposed algorithm contains attitude determination using double-differentiated carrier phase and 2 baseline configuration whcih provide more practical applications than 3 baseline.