Journal of the Korean Magnetic Resonance Society (한국자기공명학회논문지)

Korean Magnetic Resonance Society (한국자기공명학회)
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Four New Furanosesquiterpenes Isolated from the Marine Sponge Dysidea species

  • Yeong Du Yoo (Department of Oceanography, Kunsan National University) ;
  • Jung-Rae Rho (Department of Oceanography, Kunsan National University)
  • Received : 2023.12.14
  • Accepted : 2023.12.18
  • Published : 2023.12.20
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Abstract

From a marine sponge Dysidea species, four new furanosesquiterterpenoids were isolated and characterized. Their structural elucidation was achieved through an extensive analysis employing NMR, MS data, and DFT method. Notably, all compounds shared as identical molecular formula. Compound 2 was identified as a derivative of compound 1, while compounds 3 and 4 exhibited an identical planar structure. Determination of the configurations of chiral centers in compounds 1 and 2 involved a comparative analysis between measured and calculated ECD spectra, along with the application of DP4+ probability analysis. Distinctly, the configurations of isomers 3 and 4 were established by scrutinizing proton chemical shifts based on the NOE correlation.

Keywords

Acknowledgement

This research was supported by "Regional Innovation Strategy (RIS)" through National Research Foundation of Korea (NRF) funded by the ministry Education (MOE) (2023RIS-008) and Korea Institute of Marine Science & Technology (KIMST) funded by the Ministry of Oceans and Fisheries (RS-2023-00256330, Development of risk managing technology tackling ocean and fisheries crisis around Korean Peninsula by Kuroshio Current).

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