• Title/Summary/Keyword: compartments

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Nuclear Bodies Built on Architectural Long Noncoding RNAs: Unifying Principles of Their Construction and Function

  • Chujo, Takeshi;Hirose, Tetsuro
    • Molecules and Cells
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    • v.40 no.12
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    • pp.889-896
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    • 2017
  • Nuclear bodies are subnuclear, spheroidal, and membraneless compartments that concentrate specific proteins and/or RNAs. They serve as sites of biogenesis, storage, and sequestration of specific RNAs, proteins, or ribonucleoprotein complexes. Recent studies reveal that a subset of nuclear bodies in various eukaryotic organisms is constructed using architectural long noncoding RNAs (arcRNAs). Here, we describe the unifying mechanistic principles of the construction and function of these bodies, especially focusing on liquid-liquid phase separation induced by architectural molecules that form multiple weakly adhesive interactions. We also discuss three possible advantages of using arcRNAs rather than architectural proteins to build the bodies: position-specificity, rapidity, and economy in sequestering nucleic acid-binding proteins. Moreover, we introduce two recently devised methods to discover novel arcRNA-constructed bodies; one that focuses on the RNase-sensitivity of these bodies, and another that focuses on "semi-extractability" of arcRNAs.

Computational modeling of the coronary circulation for the assessment of the coronary artery bypass through left ventricle (좌심실을 통한 관상동맥 우회술의 평가를 위한 관상순환계의 수치적 모델)

  • Shim, Eun-Bo;Kamm, Roger D.
    • Proceedings of the KSME Conference
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    • 2000.11b
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    • pp.385-390
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    • 2000
  • In this study we propose the computational model for the coronary circulation. The bypass from left ventricle is also considered. Lumped parameter model with three compartments in the coronary circulation is implemented in this study. We connected the coronary artery compartment with left ventricle to explain the bypass procedure from left ventricle. The asymmetric resistance is assumed in the bypass line from left ventricle. The present numerical method is tested for normal coronary circulation and the results are compared with the existing computational work. The bypass simulation is conducted and the flow pattern is delineated. The effect of shunt resistance and coronary compliance to circulation is investigated for the better design of the bypass shunt.

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The Use of Noise Dampening Mats to Reduce Heavy-Equipment Noise Exposures in Construction

  • Saleh, Sabah;Woskie, Susan;Bello, Anila
    • Safety and Health at Work
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    • v.8 no.2
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    • pp.226-230
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    • 2017
  • The performance of sound barriers was evaluated to determine their technical effectiveness and practicality in reducing noise exposures to operating engineers in construction. Commercially purchased sound dampening mats (SDMats) were installed inside three heavy-equipment engine compartments. Sound pressure levels (SPLs) were measured before and after installing the SDMats while the equipment was on idle and full-throttle settings where it normally operates. SPLs inside the heavy-equipment operator cabs were significantly reduced by 5.6-7.6 dBA on the full-throttle setting following installation of the SDMats (p < 0.01). The evaluated engineering control intervention was simple to install, affordable, and substantially reduced the engine noise reaching the heavy-equipment operator, potentially reducing reliance on hearing-protection devices to protect construction workers from noise exposures.

Improvement of Interior Booming Noise in the Vehicle Using the Structural Dynamic Modification (구조물 동특성 변경을 이용한 실내 부밍 소음 개선)

  • Kim, Young-Ha;Lee, Jae-Woong;Kim, Sung-Gi
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2012.04a
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    • pp.354-359
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    • 2012
  • Improvement of structure-borne noises in the vehicle compartments has been one of the primary concerns in the development of vehicles. The booming is an annoying low frequency interior noise and vibration in vehicle. But it is difficult to reduce the structure-born booming noise in traditional method - trial and error within the shorten development schedule. So in present, the structure dynamic modification (SDM) method helpful to predict the effect of the local mass, stiffness, and damping is introduced. So in order to reduce the interior booming noise, the SDM was performed, and verified with modal test result. It was shown that the interior booming noise was reduced as predicted.

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A Design of Communication Protocol for Fire Detection by Using MANGO ZDK Development Tool (MANGO ZDK 개발툴을 이용한 화재감지용 통신 프로토콜 개발)

  • Yun, Dong-Yol;Joo, Young-Hoon;Kim, Sung-Ho
    • Proceedings of the KIEE Conference
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    • 2007.04a
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    • pp.426-429
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    • 2007
  • When a fire happens in builds or apartments, peoples are tend to be caught in dangerous situations owing to the failure of searching escape route to the outside. In this work, an efficient fire detection and alarm system which makes it possible for the escapers to take adequate actions is proposed. The proposed system consists of two parts. One is fire detection modules which are located at each compartments in a building. The other is fire warning modules equipped with portable flashes having ability of visual/voice warning. Fire detection information is transmitted between each modules wirelessly. In this work, an efficient communication protocol for sensor network-based fire detection system is proposed and its feasibility is verified by practical experiments using MANGO ZDK Development tools

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Environmental Risk Assessment of Cadmium using National Monitoring Data (수질 및 토양오염 모니터링 결과를 이용한 카드뮴의 환경위해성평가)

  • Park Kwangsik;Shin Dong-chun
    • Environmental Analysis Health and Toxicology
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    • v.19 no.1
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    • pp.65-72
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    • 2004
  • Environmental risk assessment of cadmium compounds was conducted using national monitoring data of aquatic and terrestrial compartments of local area. Aquatic and terrestrial toxicities of cadmium compounds on algae, daphnid, fish, earthworm, springtails and other species were evaluated. The toxicity data evaluated in this study were mainly from ECOTOX database provided by US EPA. Assessment factors were determined according to the EU technical guidance document and/or OECD proposal. Predicted no effect concentration (PNEC) values of aquatic and terrestrial toxicity were 25$\mu\textrm{g}$/L and 0.2 mg/kg, respectively and they were compared with cadmium exposure data of several local areas, which were used as Predicted exposure concentration(PEC) values. Most of the local area were found to be not risky. However, the risk values (PEC/NEC) of some metropolitan areas were greater than 1 when the most conservative PNEC value was applied.

Indoor Noise Analysis of Naval Combat Service Support Boat (전투근무지원정 격실의 실내 소음 분석)

  • Park, Mi-You;Han, Hyung-Suk;Cho, Heung-Gi
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2011.04a
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    • pp.91-96
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    • 2011
  • The ship working environment of combat service support boat is very inferior to the ground working environment. For this reason, the crew of a combat service support boat suffer from an occupational disease such as hardness of hearing. Owing to its small size and low status, the improvement of its working and residential environment is occasionally ignored and its indoor noise was not fully investigated. In this study, for improving its residential environment indoor, the indoor noise of its shipboard compartments was analysed.

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A Study on the Space Composition of Dong-gok Jaesa (동곡재사(東谷齋舍)의 공간구성에 관한 연구(硏究))

  • Yoo, In-Ho;Ha, Heon-Jeong
    • Journal of the Korean Society of Industry Convergence
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    • v.12 no.3
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    • pp.121-128
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    • 2009
  • This study is for getting sacrificial service, discussing process of sacrificial rituals and understanding the composition of space in Dong-gok Jaesa. For these things, we're arranged for exact blueprint through actual survey and analyzed the architectural features. Dong-gok Jaesa has features which show centripetal space organization with strong closing sparsely. This is intended for sincerity during ritual which is processed without obstruction. This is a mixed form which is unified both straight dwelling and Jung Dang Hyeop Sil type. And this is for all functions which is necessary for Jaesa architecture in only one building. And this is used with organizing technique for space utility with connection of compartments and various enlargement and partition. Through these things, even though it is not a big Jaesa, it shows that this is Korea traditional composition of space technique according to several purposes.

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Response Analysis of the Coronary Circulation Under the T-PLS Operation via a Lumped System Model (집중시스템 모델을 이용한 이중박동 생명보조장치 작동하의 관상순환계 반응해석)

  • Ko, Hyung-Jong;Park, Jong-Cheon;Shim, Eun-Bo
    • Journal of the Korean Society of Industry Convergence
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    • v.12 no.1
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    • pp.27-33
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    • 2009
  • In this paper, a computational analysis using a lumped system model is performed to investigate the hemodynamics of coronary circulation under the operation of T-PLS relevant to the cardiac arrest cases. The coronary circulation system is assumed to be comprised of three compartments: coronary arteries, coronary capillaries, and coronary veins. The effect of myocardial muscle contraction or relaxation is represented by temporal variations in the bias pressure. To verify the present method, we analyzed the coronary circulation for normal case and then compared the results with the existing data. Numerical results on the cardiac arrest model showed that T-PLS can increase LAD flow significantly.

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A Development of Remote Environmental Home Doctor System Using GIS (GIS를 이용한 원격 환경홈닥터 시스템 구축에 관한 연구)

  • 최병길;라영우;김중식;최재훈
    • Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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    • 2004.11a
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    • pp.435-440
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    • 2004
  • In this study, it is aimed to construct a remote home doctor system utilizing GIS technique. Remote home doctor system consists of three major compartments ; full-duplex communication system, visible communication system, and data backup system. On this system, a company request home doctor is connected with environment specialists and pollution control equipment company. The database in this system consists of spatial data and attribute data. Spatial data are made by topographic data and company location data. Attribute data consists in document data, status of company, products, amount of raw material used, odor discharge process, pollution discharge information and prevention equipments.

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