• 품질경영학회지
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• 제46권4호
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• pp.821-842
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• 2018

Purpose: To derive key requirements and key technologies for weapon system acquisition business by using Qualify Function Deployment (QFD), and to reduce business cost by setting the target performance and key expense of weapon system. Methods: We propose a QFD methodology that can induce rational decision-making by translating analyst's subjective opinions into quantitative values when analyzing requirements at the initial stage of weapon system development project. Based on QFD methodology, QFD application model combining house of quality, value engineering, and analogy cost estimating technique is presented. Results: It was possible to analyze the specific requirements necessary for the development of the weapon system, to solve the communication problem of the participants, to set clear development direction and target. Conclusion: By applying the QFD application model at the early stage of the weapon system acquisition project, it is possible to reduce the business cost by establishing clear development direction and goal through the procedural analysis process.

• Journal of Radiation Protection and Research
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• 제46권4호
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• pp.160-169
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• 2021

Background: Dual-energy X-ray images (DEI) can distinguish or improve materials of interest in a two-dimensional radiographic image, by combining two images obtained from separate low and high energies. The concepts of DEI performance describing the performance of double-exposure DEI systems in the Fourier domain been previously introduced, however, the performance of double-exposure DEI itself in terms of various parameters, has not been reported. Materials and Methods: To investigate the DEI performance, signal-difference-to-noise ratio, modulation transfer function, noise power spectrum, and noise equivalent quanta were used. Low- and high-energy were 60 and 130 kVp with 0.01-0.09 mGy, respectively. The energy-separation filter material and its thicknesses were tin (Sn) and 0.0-1.0 mm, respectively. Noise-reduction (NR) filtering used the Gaussian-filter NR, median-filter NR, and anti-correlated NR. Results and Discussion: DEI performance was affected by Sn-filter thickness, weighting factor, and dose allocation. All NR filtering successfully reduced noise, when compared with the dual-energy (DE) images without any NR filtering. Conclusion: The results indicated the significance of investigating, and evaluating suitable DEI performance, for DE images in chest radiography applications. Additionally, all the NR filtering methods were effective at reducing noise in the resultant DE images.

• Genomics & Informatics
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• 제20권2호
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• pp.17.1-17.11
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• 2022

Genetic associations have been quantified using a number of statistical measures. Entropy-based mutual information may be one of the more direct ways of estimating the association, in the sense that it does not depend on the parametrization. For this purpose, both the entropy and conditional entropy of the phenotype distribution should be obtained. Quantitative traits, however, do not usually allow an exact evaluation of entropy. The estimation of entropy needs a probability density function, which can be approximated by kernel density estimation. We have investigated the proper sequence of procedures for combining the kernel density estimation and entropy estimation with a probability density function in order to calculate mutual information. Genotypes and their interactions were constructed to set the conditions for conditional entropy. Extensive simulation data created using three types of generating functions were analyzed using two different kernels as well as two types of multifactor dimensionality reduction and another probability density approximation method called m-spacing. The statistical power in terms of correct detection rates was compared. Using kernels was found to be most useful when the trait distributions were more complex than simple normal or gamma distributions. A full-scale genomic dataset was explored to identify associations using the 2-h oral glucose tolerance test results and γ-glutamyl transpeptidase levels as phenotypes. Clearly distinguishable single-nucleotide polymorphisms (SNPs) and interacting SNP pairs associated with these phenotypes were found and listed with empirical p-values.

• 한국멀티미디어학회논문지
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• 제24권7호
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• pp.953-965
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• 2021

The research of combining virtual reality technology with the design elements of children's picture book education is a relatively new topic in virtual reality technology in recent years. Based on the combination of picture book design elements with virtual reality technology and the development of a children's picture book teaching game, this article analyzes the effectiveness of the application of virtual reality technology in children's teaching, and explores the usability of picture book design elements in teaching [1]. Through literature research methods, practical research methods and investigation research methods, this paper lucubrates the application of virtual reality technology in the design elements of children's picture book education so as to provide adequate theoretical and practical support for the research theme. The spatial positioning, vision, sound, and functional requirements of children's picture book games play a leading role in teaching. Practical statistics have proved that it is easier to promote children's mastery of teaching knowledge in a virtual environment. Moreover, use VR's game management function and setting function to solve the boringness of traditional education methods and the limitations of the teaching environment. The feasibility of game operation provides a virtual teaching platform system for children's education, and the teaching effect is remarkable.

• Mass Spectrometry Letters
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• 제13권4호
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• pp.115-124
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• 2022

Emerging evidence has shown that RNA-binding proteins (RBPs) dynamically regulate all aspects of RNA in cells and involve in major biological processes of RNA, including splicing, modification, transport, transcription and degradation. RBPs, as powerful and versatile regulatory molecule, are essential to maintain cellular homeostasis. Perturbation of RNA-protein interactions and aberration of RBPs function is associated with diverse diseases, such as cancer, autoimmune disease, and neurological disorders. Therefore, it is crucial to systematically investigate the RNA-binding proteome for understanding interactions of RNA with proteins. Thanks to the development of the mass spectrometry, a variety of proteome-wide methods have been explored to define comprehensively RNA-protein interactions in recent years and thereby contributed to speeding up the study of RNA biology. In this review, we systematically described these methods and summarized the advantages and disadvantages of each method.

• Structural Engineering and Mechanics
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• 제87권6호
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• pp.555-574
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• 2023

An efficient optimization algorithm and damage-sensitive objective function are two main components in optimization-based Finite Element Model Updating (FEMU). A suitable combination of these components can considerably affect damage detection accuracy. In this study, a new hybrid damage-sensitive objective function is proposed based on combining two different objection functions to detect the location and extent of damage in structures. The first one is based on Generalized Pseudo Modal Strain Energy (GPMSE), and the second is based on the element's Generalized Flexibility Matrix (GFM). Four well-known population-based metaheuristic algorithms are used to solve the problem and report the optimal solution as damage detection results. These algorithms consist of Cuckoo Search (CS), Teaching-Learning-Based Optimization (TLBO), Moth Flame Optimization (MFO), and Jaya. Three numerical examples and one experimental study are studied to illustrate the capability of the proposed method. The performance of the considered metaheuristics is also compared with each other to choose the most suitable optimizer in structural damage detection. The numerical examinations on truss and frame structures with considering the effects of measurement noise and availability of only the first few vibrating modes reveal the good performance of the proposed technique in identifying damage locations and their severities. Experimental examinations on a six-story shear building structure tested on a shake table also indicate that this method can be considered as a suitable technique for damage assessment of shear building structures.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제14권2호
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• pp.98-104
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• 2014

Locality-sensitive hashing techniques have been developed to efficiently handle nearest neighbor searches and similar pair identification problems for large volumes of high-dimensional data. This study proposes a locality-sensitive hashing method that can be applied to nearest neighbor search problems for data sets containing both numerical and categorical attributes. The proposed method makes use of dual hashing functions, where one function is dedicated to numerical attributes and the other to categorical attributes. The method consists of creating indexing structures for each of the dual hashing functions, gathering and combining the candidates sets, and thoroughly examining them to determine the nearest ones. The proposed method is examined for a few synthetic data sets, and results show that it improves performance in cases of large amounts of data with both numerical and categorical attributes.

• 한국컴퓨터정보학회논문지
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• 제21권5호
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• pp.127-133
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• 2016

In this paper, an intelligent dimming control system is designed and implemented with the human visual response function using CDS sensor, PIR sensor and temperature sensor, etc. The proposed system is designed to detect a moving object by PIR sensor and to control the LED dimming considering the human visual response. Also, the dimming of LED light can modulate on the app, and simultaneously control dimming in real-world environments with smart phone app. A high-temperature warning or a fire hazard information is transmitted to user's smart phone according to sensor values and Data graph are provided as part of data visualization. Connecting the hardware controller, the proposed intelligent smart dimming control system is expected to contribute to the power reduction interior LED, smart grid building and saving home combining with internet of things.

• 전기학회논문지
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• 제60권12호
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• pp.2293-2298
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• 2011

In this paper, A tag antenna structure for RFID application with resonant frequency of 920MHz is proposed using the meander line technique and Evolution Strategy. Miniaturization structure design for a tag antenna is performed by structure combining the half-wave dipole with a meander line. To achieve this, an interface program between a commercial EM analysis tool and the optimal design program is made for implementing the evolution strategy technique that seeks a global optimum of the objective function through the iterative design process consisting of variation and reproduction. The optimized tag antenna size is 63mm ${\times}$ 15mm ${\times}$ 1mm. And the proposed antenna is realized on FR-4 substrate (${\epsilon}_r=4.4$, $tna{\delta}=0.02$).

• International Journal of Aerospace System Engineering
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• 제4권1호
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• pp.1-8
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• 2017

This paper proposes the load distribution control allocation technique. The proposed method is designed by combining a conventional control allocation method with load distribution ability in order to reduce the stress acting on ailerons. By designing the weighting matrix as a function of the load distribution rule, the optimal deflection angles of each surface to satisfy both control goal and load distribution can be achieved. Moreover, rule based fault-tolerant control technique is also proposed. The rules are generated by considering both dominant control surfaces and the ratio of load distribution among surfaces. The performance of the proposed method is evaluated through numerical simulations.