• Title/Summary/Keyword: central function

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A Study on Reverse Design of Cam Mechanism using NURBS (NURBS를 이용한 캠 기구의 역설계에 관한 연구)

  • 김상진;신중호;김대원;윤호업
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2002.10a
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    • pp.920-924
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    • 2002
  • This paper presents the reverse design of a cam mechanism using NURBS(Nonuniform Rational B-spline curve). Cam is very difficult to make the accurate shape on the design and the manufacture. Because the cam shape is commonly made in order to move in special functions. The reverse design can be used to check accuracy between the designed data and the manufactured data of the cam shape and also reproduce the cam without the design data. The reverse design procedures consist of motion analysis and curve fitting. The motion analysis is used the central difference method and the relative velocity method to find the displacement and velocity. The curve fitting is used NURBS to develope the whole curve. The central difference method is derived in the 3 dimensional space.

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The Characteristics of KM Clinical Trials - Focusing on the Clinical Research Information Service (CRIS) (한약 임상시험의 특성 : 질병관리본부 임상연구정보서비스(CRIS)를 중심으로)

  • Jeung, Chang-woon;Jeon, Sun-woo;Jo, Hee-Geun
    • The Journal of Internal Korean Medicine
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    • v.41 no.6
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    • pp.959-966
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    • 2020
  • Objectives: To examine the fundamental characteristics of interventional clinical trials registered in the CRIS (Clinical Research Information Service) database. Methods: We systematically analyzed the status of Korean medical interventions using the search function of the CRIS database. Results: From 2010 to January 2020, 267 Korean medicine-related clinical trials were registered with CRIS. The studies, which included many randomized trials (80.14%), focused primarily on demonstrating the effectiveness and safety of acupuncture and Korean herbal remedies. Most of these studies were government-sponsored and researcher-led clinical trials, but a few were company-sponsored trials. All trials were small and need improvement. Conclusion: This study reviews the current status of clinical trials in the field of Korean medicine and the basic data that can be used to create evidence-based Korean medicine.

Probabilistic tunnel face stability analysis: A comparison between LEM and LAM

  • Pan, Qiujing;Chen, Zhiyu;Wu, Yimin;Dias, Daniel;Oreste, Pierpaolo
    • Geomechanics and Engineering
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    • v.24 no.4
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    • pp.399-406
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    • 2021
  • It is a key issue in the tunnel design to evaluate the stability of the excavation face. Two efficient analytical models in the context of the limit equilibrium method (LEM) and the limit analysis method (LAM) are used to carry out the deterministic calculations of the safety factor. The safety factor obtained by these two models agrees well with that provided by the numerical modelling by FLAC 3D, but consuming less time. A simple probabilistic approach based on the Mote-Carlo Simulation technique which can quickly calculate the probability distribution of the safety factor was used to perform the probabilistic analysis on the tunnel face stability. Both the cumulative probabilistic distribution and the probability density function in terms of the safety factor were obtained. The obtained results show the effectiveness of this probabilistic approach in the tunnel design.

SEAS (Symbolic Editing and Design Aid System) (회로도면과 IC Mask Layout을 위한 2차원 Grphic Editor)

  • Jo, Jae-Joo;Cha, Gun-Up;Kim, Jung-Soon
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.24 no.1
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    • pp.149-158
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    • 1987
  • This paper describes the SEAS which is a 2-dimensional graphic editor for schematic circuit and IC mask layout. This system runs on general purpose computer and Tektronix 4110 series graphic terminal. With this system, user can edit schematic circuits and/or IC mask layout with 2 level hierarchy. This system supports more than 20 kinds of built-in symbol, user definable internal symbols, 60 macros, 16 function keys, 4 level on-screen menu operation and edit-in-place of cell in main drawing. And it provides editing functions such as reflection, rotation, move and copy of one or a group of elements, and modification of polygona geometry etc. To improve the excution speed, we used local memory of graphic terminal. For the portability of the program, the system is written in FORTRAN 77 programming language.

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Compound IKD-8344, a Selective Growth Inhibitor Against the Mycelial Form of Candida albicans, Isolated from Streptomyces sp. A6792

  • HWANG EUI IL;YUN BONG SIK;YEO WOON HYUNG;LEE SANG HAN;MOON JAE SUN;KIM YOUNG KOOK;LIM SE JIN;KIM SUNG UK
    • Journal of Microbiology and Biotechnology
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    • v.15 no.4
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    • pp.909-912
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    • 2005
  • In the course of screening for selective growth inhibitors against the mycelial form of Candida albicans, we isolated a Streptomyces sp. A6792 from soils. The inhibitor was isolated from the above bacterium and identified through several spectral analyses with UV and mass spectrophotometries, and various NMR. The compound was determined to be a macrocyclic dilactone antibiotic, IKD-8344 (molecular weight: 844, molecular formula: $C_{48}H_{76}O_{12}$). The compound selectively inhibited the growth of mycelial form of C. albicans with an MIC of 6.25 ${\mu}g/ml$. It also exhibited strong inhibitory effect preferentially on the mycelial form of various Candida spp. including C. krusei, C. tropicalis, and C. lusitaniae, with MICs ranging from 1.56 to 25 ${\mu}g$/ml. Furthermore, the compound showed no significant toxicity against SPF ICR mice up to 60 mg/kg. These results suggest that IKD-8344 is a useful lead compound for the development of novel antifungal agents, based on the preferential growth inhibition against Candida spp.

A Study of Comparing Shamans' Costumes of the Central Region of Korea with those of Siberia and Central Asia (시베리아·중앙아시아와 한국 중부지방 무속복식의 비교연구)

  • Lee, Ja-Yeon
    • Fashion & Textile Research Journal
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    • v.7 no.4
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    • pp.387-393
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    • 2005
  • This study compares shamans' costumes of Korea with those of Siberia and Central Asia. It also investigates the meaning of shamanism and shamans,the relationship of Korean shamanism to shamanism, and the genealogy of Korean shamanism. For collecting and analyzing data of the research, literature reviews, field studies, and the investigation of historical relics are mostly used. The following are the major findings of the research: Through the comparison of shamans' costumes of Korea with those of Siberia and Central Asia, this research finds out some similarities and differences in the costumes. Both Korean shamans and Siberian and Central Asian shamans wore shaman's costumes and used utensils like bells or mirrors when they perform a religious service. On their costumes, they both used an element which stands for birds. However, they were different in terms of the materials or styles of the costumes, of the function of the costumes, and of the decorating with ornaments. The differences in the materials or styles of the costumes, different functions of the costumes, and using ornaments or not can be viewed as a general phenomenon, which is resulted from different environments. The soul's departing the body or the possession or a mixed method can be considered as mere variations due to regional or cultural differences. In conclusion, based on the comparison of the costumes of shamans of Korea with those of Siberia and Central Asia, the shamans of Korea and Siberia and Central Asia share the same origin. And the genealogy of Korean shamans can be said to be originated from the northern shamanism.

Isolation and characterization of LHT-type plant amino acid transporter gene from Panax ginseng Meyer

  • Zhang, Ru;Zhu, Jie;Cao, Hong-Zhe;Xie, Xiao-Lei;Huang, Jing-Jia;Chen, Xiang-Hui;Luo, Zhi-Yong
    • Journal of Ginseng Research
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    • v.37 no.3
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    • pp.361-370
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    • 2013
  • A lysine histidine transporter (LHT) cDNA was isolated and characterized from the roots of Panax ginseng, designated PgLHT. The cDNA is 1,865 bp with an open reading frame that codes for a protein with 449 amino acids and a calculated molecular mass of 50.6 kDa with a predicted isoelectric point of 8.87. Hydropathy analysis shows that PgLHT is an integral membrane protein with 9 putative membrane-spanning domains. Multiple sequence alignments show that PgLHT shares a high homology with other plant LHTs. The expression profile of the gene was investigated by real-time quantitative polymerase chain reaction during various chemical treatments. PgLHT was up-regulated in the presence of abscisic acid, salicylic acid, methyl jasmonate, NaCl, and amino acids. To further explore the function of PgLHT gene, full-length cDNA of PgLHT was introduced into P. ginseng by Agrobacterium rhizogenes A4. The overexpression of PgLHT in the hairy roots led to an obviously increase of biomass compared to the controls, and after addition of the amino acids, the overexpressed-PgLHT hairy roots grew more rapidly than untreated controls during early stage of the culture cycle. The results suggested that the PgLHT isolated from ginseng might have role in the environmental stresses and growth response.

On Estimating the Hazard Rate for Samples from Weighted Distributions

  • Ahmad, Ibrahim A.
    • International Journal of Reliability and Applications
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    • v.1 no.2
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    • pp.133-143
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    • 2000
  • Data from weighted distributions appear, among other situations, when some of the data are missing or are damaged, a case that is important in reliability and life testing. The kernel method for hazard rate estimation is discussed for these data where the basic large sample properties are given. As a by product, the basic properties of the kernel estimate of the distribution function for data from weighted distribution are presented.

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Some Results About $NBU_{mgf}$ Class of Life Distributions

  • Ahmad, I.A.;Kayid, M.
    • International Journal of Reliability and Applications
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    • v.5 no.4
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    • pp.155-162
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    • 2004
  • A new class of life distributions is studied. This class is defined based on comparing the residual life to the whole life in the moment generating function order giving "the new better than used in the moment generating function order ageing class ($NBU_{mgf}$)". Some new results of this class are given including some closere properties and characterizations. Finally testing exponentially against the $NBU_{mgf}$ class is also addressed.

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