• 한국어류학회지
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• 제10권1호
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• pp.115-127
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• 1998

조피볼락의 소화관은 인두, 식도, 위, 장, 항문 그리고 10~11개의 유문수로 이루어져 있다. 유문수는 위의 유문부 말단에서 유래하며 바나나 형태의 맹낭을 형성하고 있다. 어체 체장에 대한 식도에서 항문까지의 소화관 길이의 비 (relative length of gut: RLG)는 1.56(n=10)이다. 식도의 근육층은 바깥쪽의 앓은 종주근층과 안쪽의 두꺼운 환상근층으로 구성된다. 점막상피층은 정단부에 짧은 미세융모를 가진 원주상피로 구성되며, 다수의 점액분비세포들을 가진다. 위의 점막주름은 규칙적으로 배열되었으며, 근육층은 종주근, 사주근, 환상근층으로 구성된다. 위선의 주세포는 관상의 미토콘드리아와 소포체 그리고 전자밀도가 높은 다수의 분비과립을 가지지만, 부세포는 소형의 미토콘드리아와 소포체 그리고 전자밀도가 낮은 액포를 가진다. 유문수와 장의 점막상피층은 주로 원주상피세포, rodlet cell 그리고 dark cell로 구성된다. 흡수기능을 가진 원주세포들은 발달된 미토콘드리아, 소포체, 전자밀도가 높은 과립상 물질, 음작용포 그리고 다포체를 가진다. Rodlet cell은 발달된 cytoplasmic capsule을 가지며 세포질에는 소포체가 잘 발달되어 있다. Dark cell의 세포질에는 전자밀도가 높고, 미토콘드리아들이 잘 발달되어 있다. 원주상피세포는 세포연접이 발달되어 있고, 상부에는 미세융모가 잘 발달되어 있으며, 미세융모의 내부에서는 세포질에서부터 시작된 actin filament를 관찰할 수 있다. 장 상피의 미세융모는 유문수의 미세융모 보다 길며, 배상세포의 수도 정상피에 더 많다.

• 종양간호연구
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• 제8권1호
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• pp.40-49
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• 2008

Purpose: This descriptive study was to investigate the quality of life in patients with hematopoietic stem cell transplantation (HSCT) from June 1 to October 13, 2007. Method: The survey was conducted in 6 different university hospitals which located in Seoul and Jeollanam-do province using the Functional Assessment of Cancer Therapy-BMT Scale (FACT-BMT) version 4. We collected a total of 155 questionnaires and analyzed 149 among them. Results: The average score of quality of life was 2.53 out of 5. Physical well being score was highest among sub-domains, followed by emotional well-being, additional concerns, social/family well-being, and functional well-being. Study subjects worried that their conditions would get worse. However study subjects didn't regret having been received HSCT. Age, duration from HSCT, age at diagnosis, income, readmission, HSCT type, educational background, marital status, and the level of activities of daily living were related to quality of life. Conclusions: The findings of this study indicates that the HSCT survivor's quality of life issue is still important and have to be investigated repeatedly in the future. That is necessary for generalizing QOL outcomes for clinical use. We also suggest to develop interventions to improve QOL.

• Transactions on Electrical and Electronic Materials
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• 제12권1호
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• pp.35-39
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• 2011

An electrically erasable programmable read-only memory (EEPROM) containing a stacked metal-insulator-metal (MIM) and n-well capacitor is proposed. It was fabricated using a 0.18 $\mu$m standard complementary metal-oxide semiconductor process. The depletion capacitance of the n-well region was effectively applied without sacrificing the cell-area and control gate coupling ratio. The device performed very similarly to the MIM capacitor cell regardless of the smaller cell area. This is attributed to the high control gate coupling ratio and capacitance. The erase speed of the proposed EEPROM was faster than that of the cell containing the MIM control gate.

• Molecules and Cells
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• 제21권3호
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• pp.343-355
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• 2006

Stem cells are unique cell populations with the ability to undergo both self-renewal and differentiation, although a wide variety of adult stem cells as well as embryonic stem cells have been identified and stem cell plasticity has recently been reported. To identify genes implicated in the control of the stem cell state as well as the characteristics of each stem cell line, we analyzed the expression profiles of genes in human embryonic, hematopoietic ($CD34^+$ and $CD133^+$), and mesenchymal stem cells using cDNA microarrays, and identified genes that were differentially expressed in specific stem cell populations. In particular we were able to identify potential hESC signature-like genes that encode transcription factors (TFAP2C and MYCN), an RNA binding protein (IMP-3), and a functionally uncharacterized protein (MAGEA4). The overlapping sets of 22 up-regulated and 141 down-regulated genes identified in this study of three human stem cell types may also provide insight into the developmental mechanisms common to all human stem cells. Furthermore, our comprehensive analyses of gene expression profiles in various adult stem cells may help to identify the genetic pathways involved in self-renewal as well as in multi-lineage specific differentiation.

• 한국세라믹학회지
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• 제36권9호
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• pp.954-964
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• 1999

The effect of fabrication variables and microstructures on the compressive strength of open cell alumina zirconia and silicon nitride ceramics fabricated by polymeric sponge method was investigated. Bulk density and compressive strength of open cell ceramics were mainly affected by coating characteristics of ceramic slurry on polymeric sponge that controlled a shape thickness and defect of the struts. Sintering temperature was optimized for enhancement of strut strength and compressive strength of open cell ceramics. Relative density and compressive strength behaviors were relatively well matched with the predicted values. Open cell ceramics of lower relative density below 0.1 prepared by first relatively well matched with the predicted values. Open cell ceramics of lower relative density below 0.1 prepared by first coating of ceramic slurry had thin triangular prismatic struts that were often broken or longitudinally cracked. With an application of second coating of slurry shape of struts was transformed into thickner cylindrical one and defects in struts were healed but the relative density increased over 0.2 Open cell zirconia had both the highest bulk density and compressive strength and alumina had the lowest compressive strength while silicon nitrides showed relatively high compressive strength and the lowest density. Based upon the analysis open cell silicon nitride was expected to be one of potential structural ceramics with light weight.

• 대한전자공학회논문지
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• 제23권6호
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• pp.988-994
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• 1986

We present an automated CMOS standard cell design mehtodology which generates a mask description in the CIF (Caltech Intermediate Form)from a user-given logic description and design rule. The resultant layout reflects the user's choice among N-well, P-well and twin-well process and user's decision whether the guard band is to be included or not. Noise margin of each cell was improved by carefully adjusting the channel width of P-FET.

• BMB Reports
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• 제43권10호
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• pp.664-669
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• 2010

The present study aimed to investigate the membrane stabilizing effect of Thymoquinone (TQ) on cell surface glycoconjugates and cytokeratin expression against DMBA induced hamster buccal pouch carcinogenesis. 0.5% DMBA painting (three times per week) in hamster buccal pouches for 14 weeks resulted in the formation of well developed oral squamous cell carcinoma. We observed 100% tumor formation with marked abnormalities of glycoconjugates status in tumor bearing hamsters as compared to control animals. Oral administration of TQ at a dose of 30 mg/kg body weight, to DMBA painted hamsters on alternate days for 14 weeks, reduced the tumor formation as well as protected the levels of cell surface glycoconjugates in DMBA painted hamsters. The present study thus suggests that TQ has potent chemopreventive efficacy as well as protected the abnormalities on cell surface glycoconjugates during DMBA induced hamster buccal pouch carcinogenesis.

• 한국통신학회논문지
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• 제15권8호
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• pp.639-647
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• 1990

음성 인식에서의 dynamic time warp(DTW)은 반복적 계산을 필요로 하며, 이 계산을 수행하기에 합당한 PE cell의 설계는 매우 중요하다. 따라서 이 연구에서는 실제에 가까운 실시간 어휘 인식을 가능하게 하는 large dictionary 의 DTW 알고리즘을 hardware로 구현하기 위한 PE(Processing Element) cell의 설계에 주안점을 두었다. 이 DTW 용 PE cell은 크게 세가지의 블록으로 대별된다. 즉 MIN block, ADD block 그리고 ABS block인데, "MIN"은 accumulated minimum distance를 계산하기 위한 블록이고 "ADD"는 이들 minimum distance들의 합을 계산하는 블록, 그리고"ABS"는 이러한 합에 의한 local distance의 절대값을 구하기 위한 블록이다. 본 연구에서는 이들 세가지 블록중 MIN 회로의 설계 및 검증을 행하였으며, 3um CMOS N-well 설계 규칙에 따라 MIN 블록에 대한 레이아웃을 행한 후 설계 규칙 검사(DRC)를 마쳤다.레이아웃을 행한 후 설계 규칙 검사(DRC)를 마쳤다.

• 한국임상수의학회지
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• 제13권1호
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• pp.81-86
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• 1996

Systemic lupus erythematosus in a dog, suspected systemic lupus erythematosus in a dog, and autoimmune thrombocytopenic purpura hemmorrhagica in a dog are reported. A fice-year old, female Chihuahua (Case 1) showed initially hemorrhagic diathesis and purpura hemorrhagica. Afterward, it showed polymyositis and polyarthritis. LE-cell was demonstrated on LE-cell preparation trom blood. Systemic lupus erythematosus was diagnosed. This reponded well to the immunosuppressants, but developed iatrogenic Cushing syndrome and steroid hepatopathy. A two-and-half-year old, male toy poodle (Case 2) had chief complaint of red urine. Occult blood test for the urine sediment. This did not respond at all to antibiotics and carbazochrome, which is one of systemic coagulants. LE-cell was demonstrated on LE-cell preparation from blood. This responded relatively well to immunosupressants such as prenisolone, azathioprine and cyclophosphamide. systemic lupus erythematosus is suspected. A nine-year-and-three-month old, female Maltese (Case 3), which had history of congestive heart failure and ovariohysterectomy showed purpura hemorrhagica in the skin of chest. This had severe thrombocytopenia and leukocytosis. As prednisolone was administered before immunological examination or demonstration of LE-cell, it was impossible to diagnose whether purpura hemorrhagica developed as a member of systemic lupus erythematosus or independent of systemic lupus erythematosus. This responded well to prednisolone, and so autoimmune thrombocytopenic purpura hemorrhagica was diagnosed.

• Imaging Science in Dentistry
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• 제48권4호
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• pp.233-244
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• 2018

Purpose: Oral carcinoma cuniculatum is a rare well-differentiated variant of oral squamous cell carcinoma. The purpose was to systematically review its unique features to differentiate it from other variants as verrucous carcinoma, papillary squamous cell carcinoma and well-differentiated squamous cell carcinoma. Materials and Methods: A systematic review was performed using MEDLINE, Dentistry and Oral Sciences Source and PubMed databases and any existing articles related to the research subject missed in the search strategy to screen ones reporting cases occurring exclusively in the oral cavity in English literature. Variables analyzed included clinical, etiologic, imaging, histopatholgical features, treatment, follow-up and survival rates. Results: From 229 hits, 17 articles with 43 cases were included in the systematic review. Clinically it showed a female predilection with pain and/or ulceration of a relatively long duration and exudation being the most common symptoms. Histologically, it showed more endophytic features comprising well-differentiated squamous epithelium with absent or minimal cytological atypia and multiple keratin filled crypts or cuniculus. Inflammatory stromal reaction and discharging abscesses were reported in most of the cases. Bone destruction was predominant in most imaging features. Complete surgical resection with a safety margin was the treatment of choice in most of the cases with few recorded recurrence cases. Conclusion: Apprehensive knowledge of oral carcinoma cuniculatum unique features is essential to avoid its misdiagnosis and provide proper treatment especially for recurrent cases.