• The Korean journal of internal medicine
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• v.39 no.1
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• pp.123-136
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• 2024

Background/Aims: Despite short-acting β₂-agonist (SABA) overuse being associated with poor asthma outcomes, data on SABA use in South Korea is scarce. Herein, we describe prescription patterns of SABA and other asthma medications in patients from the South Korean cohort of the SABA use IN Asthma (SABINA) III study. Methods: This study included patients with asthma aged ≥ 12 years, who had ≥ 3 consultations with the same healthcare provider, and medical records containing data for ≥ 12 months prior to the study visit. Patients were classified by investigator-defined asthma severity (per 2017 Global Initiative for Asthma recommendations) and practice type (primary or specialist care). Data on disease characteristics, asthma treatments, and clinical outcomes in the 12 months before the study visit were collected using electronic case report forms. Results: Data from 476 patients (mean age, 55.4 years; female, 63.0%) were analyzed. Most patients were treated by specialists (83.7%) and had moderate-to-severe asthma (91.0%). Overall, 7.6% of patients were prescribed ≥ 3 SABA canisters (defined as over-prescription). In patients prescribed SABA in addition to maintenance therapy, 47.4% were over-prescribed SABA. Most patients (95.4%) were prescribed a fixed-dose combination of an inhaled corticosteroid and a long-acting β₂-agonist as maintenance therapy. Although asthma was well-controlled/partly-controlled in 91.6% of patients, 29.6% experienced ≥ 1 severe asthma exacerbation. Conclusions: SABA over-prescription was reported in nearly 50% of patients prescribed SABA in addition to maintenance therapy, underscoring the need to align clinical practices with the latest evidence-based recommendations and educate physicians and patients on appropriate SABA use.

• Transactions of the Korean Society of Automotive Engineers
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• v.13 no.3
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• pp.17-23
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• 2005

In this study, the high strength and superior toughness spring steels as the suspension material, used for automobile and railroad industries were utilized to carry out the following investigations. Corrosion times were controlled in 7, 14,30 and 60days to examine the relation between corrosion pit and compressive residual stress in the static corrosion environment after shot peened. And then corrosion current and corrosion potential were measured for every 24 hours to investigate the corrosion mechanism. Shot peened material shows the low or rate of corrosion current as compared with unpeened material. In case of hot peened material which has the highest residual stress, it has a low corrosion current density.

• Proceedings of the KSME Conference
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• 2004.11a
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• pp.319-324
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• 2004

In this study, the high strength and superior toughness spring steels as the suspension material, used for automobile and railroad industries were utilized to carry out the following investigations. Corrosion times were controlled in 7, 14, 30 and 60days to examine the relation between corrosion pit and compressive residual stress in the static corrosion environment after shot peened. And then corrosion current and corrosion potential were measured for every 24 hours to investigate the corrosion mechanism. Shot peened material shows the low or rate of corrosion current as compared with unpeened material. In case of peened material which has the highest residual stress, it has a low corrosion current density.

• Korean Management Science Review
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• v.9 no.1
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• pp.3-15
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• 1992

In this paper, we study a manufacturing system of serial stages with general service times, in which the production of each stage and the coordination of stages are controlled by Kanban discipline. This Kanban discipline is modeled as a Discrete Event Dynamic System and a system of recursive equations is applied to study the dynamics of the system. The recursive relationship enables us to compare this Kanban discipline with the other blocking disciplines such as transfer blocking, service blocking, block-and-hold b, and block-and-hold K, and the Kanban is shown to be superior to the other disciplines in terms of makespan and throughput. As a special case, two stages Kanban system is modeled as $C_2/C_2/1/N$ queueing system, and a recursive algorithm is developed to calculate the system performance. In optimizing the system performance, the stochastic optimization approach of Robbins-Monro is employed via perturbation analysis, the way to estimate the stochastic partial derivative based on only one sample trajectory of the system, and the required commuting condition is verified. Then the stochastic convexity result is established to provide second-order optimality condition for this parametric optimization problem.

• Journal of computational fluids engineering
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• v.11 no.4 s.35
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• pp.20-25
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• 2006

In the present study, flow characteristics inside a road tunnel are simulated for the ventilation flows due to jet fan system and flows induces by the traffic. Traffic ventilation is numerically simulated by multiple reference frame. From the results of steady state simulation of tunnel ventilation, it is found that the proper ventilation is achieved by the designed jet fan system along with ventilating flow induced by the traffic. A transient simulation is also performed for the case of vehicle fire in the tunnel reversing the direction of rotation of some fans. The results suggest that the heat and smoke can be controlled by the proper changing of fan operation mode. The present results can be used to design proper ventilation system and effective smoke control system as well.

• Transactions of the Korean Society of Mechanical Engineers
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• v.19 no.8
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• pp.1964-1971
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• 1995

In the present study, the performance characteristics of a centrifugal air compressor were investigated experimentally. The PC controlled performance test facility for a centrifugal air compressor driven by an electric motor with a gear box to achieve higher compressor rotating speed was set up in the present study. The performance test for a turbocharger compressor of a diesel engine was conducted, and in a case of 34,800 rpm, pressure ratio 1.18, flow rate 0.09kg/s, compressor efficiency 61% were investigated. Adiabatic power for a tested compressor showed maximum value at mass flow ratio 0.8. The value of mass flow ratio of maximum efficiency was about 0.37, it was independent of compressor rotating speed.

• Journal of Power System Engineering
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• v.11 no.3
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• pp.59-65
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• 2007

In this study, 6-DOF simulator using pneumatic cylinder driving apparatus was manufactured because a pneumatic cylinder driving apparatus is superior to electric driving motor and hydraulic actuator, which used in traditional 6-DOF simulator, in competitive price and acceleration performance, and, 6-DOF motion can be realized at a low price in case that relatively low load is imposed on the simulator. The possible range of pose control of the simulator was investigated by inverse kinematics, and, it was controlled by a linear controller derived from linear model of the simulator. The Experimental results show that the simulator follows given coordinate well.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2008.04a
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• pp.874-875
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• 2008

Gap servo NFR (Near Field Recording) system is one of technologies to reduce beam spot size by increasing NA (Numerical Aperture) of lens. To achieve high NA, SIL (Solid Immersion Lens) is used. In case of using a blue LD (405 nm) as the light source the gap distance should be controlled under 100 nm with much tighter margin. To develop NFR disc drive with very small gap distance between SIL bottom and the surface of media, we need to research for the vibration characteristics and design considerations. This paper deals with a study on vibration characteristic of NFR disc drive.

• Journal of Korean Society for Atmospheric Environment
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• v.7 no.1
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• pp.31-40
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• 1991

This study shows the correlation between $NO_x$ emission in the exhaust gas and various operation factors of dual fuel engine for Co-generation system. General tendency was shown that the thermal efficiency was lowered by the change of operation factors. However these were not confirmed on this experiment. Increasing T4 temperature (exhaust gas temperature at turbo-charger inlet) reduces $NO_x$ emission rate. The higher T4 temperature requires lower excess air as the excess air ratio is controlled by T4 temperature on gas mode operation. Another tendency was that $NO_x$ emission rate is reduced in case of increasing boost air temperature, quantity of pilot oil or bypassing flue gas through the exhaust gas boiler. The diameter of the fuel injection nozzle was changed smaller than design value and the injection timing was readjusted. Thus $NO_x$ emission rate could be reduced as retarding injection timing and changing hole diameter of fuel injection nozzle, however maxium engine out-put was decreased by changing fuel nozzle on the diesel mode operation.

• Proceedings of the KSME Conference
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• 2000.04b
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• pp.240-245
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• 2000

In this study, thickness, density and effective thermal conductivity of frost forming on the horizontal cylinder were measured with various air temperature and humidity. Reynolds number and temperature of cooling surface are controlled 17300 and $-l5^{\circ}C$ respectively. In each case of air temperature $5^{\circ}C,\;10^{\circ}C,\;15^{\circ}C,$ varying absolute humidity, experiments were executed. In measuring frost surface temperature and thickness of frost layer, infrared thermocouples and CCD camera were used. Frost was gathered from cylinder to measure mass of frost layer. Experimental data showed that the thickness and effective thermal conductivity of the frost layer increase with respect to time. Thickness of frost layer increase with humidity increasing, and density of frost layer increase with air temperature rising. Frost growth with air temperature and density of frost layer with humidity are affected by whether dew point is below or above freezing point.