• 제목/요약/키워드: branch plants

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Ginsenosides: the need to move forward from bench to clinical trials

  • Yu, Seung Eun;Mwesige, Benjamin;Yi, Young-Su;Yoo, Byong Chul
    • Journal of Ginseng Research
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    • 제43권3호
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    • pp.361-367
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    • 2019
  • Panax ginseng, known as Koran ginseng, one of the most commonly used traditional plants, has been demonstrated to show a wide range of pharmacological applications. Ginsenosides are the major active ingredients found in ginseng and are responsible for the biological and pharmacological activities, such as antioxidation, antiinflammation, vasorelaxation, and anticancer actions. Existing studies have mostly focused on identifying and purifying single ginsenosides and investigating pharmacological activities and molecular mechanisms in cells and animal models. However, ginsenoside studies based on clinical trials have been very limited. Therefore, this review aimed to discuss the currently available clinical trials on ginsenosides and provide insights and future directions for developing ginsenosides as efficacious and safe drugs for human disease.

Evaluation of Antimicrobial Activity of the Methanol Extracts from 8 Traditional Medicinal Plants

  • Kang, Chang-Geun;Hah, Dae-Sik;Kim, Chung-Hui;Kim, Young-Hwan;Kim, Eui-Kyung;Kim, Jong-Shu
    • Toxicological Research
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    • 제27권1호
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    • pp.31-36
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    • 2011
  • The methanol extract of 12 medicinal plants were evaluated for its antibacterial activity against Gram-positive (5 strains) and Gram-negative bacteria (10 strains) by assay for minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC). The antibacterial activity was determined by an agar dilution method (according to the guidelines of Clinical and Laboratory Standard Institute). All the compounds (12 extracts) of the 8 medicinal plants (leaf or root) were active against both Gram-negative and Gram-positive bacteria. Gram-negative showed a more potent action than Gram positive bacteria. The MIC concentrations were various ranged from $0.6\;{\mu}g/ml$ to $5000\;{\mu}g/ml$. The lowest MIC ($0.6\;{\mu}g/ml$) and MBC ($1.22\;{\mu}g/ml$) values were obtained with extract on 4 and 3 of the 15 microorganisms tested, respectively.

장기사용된 1Cr-0.5Mo 주증기관의 수명평가 (Life Evaluation of Long-time Used 1Cr-0.5Mo Main Steam Pipe)

  • 백수곤;홍성인
    • Journal of Welding and Joining
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    • 제16권1호
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    • pp.70-76
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    • 1998
  • Most fossil power plants and many critical components will be approaching the end of their nominal design life. At the same time, utilities are finding it economically attractive to extend the use of these plants for several more years, Especially Main steam pipe that operated under high temperature and pressure, often under the more severe operating conditions associated with cycling duty, is most important pipe system and critical component in fossil power plant. To extend the viability of older pipe system and to improve the operation and maintenance reliability, some technologies of precise diagnosis and life management have evolved out of the necessity. The purpose of this study is to descrive the related technologies and show the example of one power plants. The purpose of this study is to descrive the related technologies and show the example of one power plants. The stress analysis was done using ANSYS FEM Code. The branch area from main steam to turbine was the high stressed zone. To evaluate the degradation of the pipe material, replica, visual check, magnetic test, hardness test were done at the welding spot. The degradation level of welding point was E/F, so the remaining life of the welded area was about 0-25%.

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Functional Characterization of NtCDPK1 in Tobacco

  • Lee, Sang Sook;Yoon, Gyeong Mee;Rho, Eun Jung;Moon, Eunpyo;Pai, Hyun-Sook
    • Molecules and Cells
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    • 제21권1호
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    • pp.141-146
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    • 2006
  • We previously showed that NtCDPK1, a tobacco calcium-dependent protein kinase, interacts with and phosphorylates the Rpn3 regulatory subunit of the 26S proteasome, and that both NtCDPK1 and Rpn3 are mainly expressed in rapidly proliferating tissues, including shoot and root meristem. In this study, we examined NtCDPK1 expression in roots using GUS expression in transgenic Arabidopsis plants, and investigated its function in root development by generating transgenic tobacco plants carrying a sense NtCDPK1 transgene. GUS activity was first detected in roots two days after sowing. In later stages, strong GUS expression was detected in the root meristem and elongation zone, as well as the initiation sites and branch points of lateral roots. Transgenic tobacco plants in which NtCDPK1 expression was suppressed were smaller, and their root development was abnormal, with reduced lateral root formation and less elongation. These results suggest that NtCDPK1 plays a role in a signaling pathway regulating root development in tobacco.

A novel approach for rice straw agricultural waste utilization: Synthesis of solid aluminosilicate matrices for cesium immobilization

  • Panasenko, A.E.;Shichalin, O.O.;Yarusova, S.B.;Ivanets, A.I.;Belov, A.A.;Dran'kov, A.N.;Azon, S.A.;Fedorets, A.N.;Buravlev, I. Yu;Mayorov, V. Yu;Shlyk, D. Kh;Buravleva, A.A.;Merkulov, E.B.;Zarubina, N.V.;Papynov, E.K.
    • Nuclear Engineering and Technology
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    • 제54권9호
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    • pp.3250-3259
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    • 2022
  • A new approach to the use of rice straw as a difficult-to-recycle agricultural waste was proposed. Potassium aluminosilicate was obtained by spark plasma sintering as an effective material for subsequent immobilization of 137Cs into a solid-state matrix. The sorption properties of potassium aluminosilicate to 137Cs from aqueous solutions were studied. The effect of the synthesis temperature on the phase composition, microstructure, and rate of cesium leaching from samples obtained at 800-1000 ℃ and a pressure of 25 MPa was investigated. It was shown that the positive dynamics of compaction was characteristic of glass ceramics throughout the sintering. Glass ceramics RS-(K,Cs)AlSi3O8 obtained by the SPS method at 1000 ℃ for 5 min was characterized by a high density of ~2.62 g/cm3, Vickers hardness ~ 2.1 GPa, compressive strength ~231.3 MPa and the rate of cesium ions leaching of ~1.37 × 10-7 g cm-2·day-1. The proposed approach makes it possible to safe dispose of rice straw and reduce emissions into the atmosphere of microdisperse amorphous silica, which is formed during its combustion and causes respiratory diseases, including cancer. In addition, the obtained is perspective to solve the problem of recycling long-lived 137Cs radionuclides formed during the operation of nuclear power plants into solid-state matrices.

경기도 내 유통 중 견과종실류 등의 멜라토닌 함량 조사 (Monitoring of Melatonin Contents in Nuts, Seeds, and Beans in Gyeonggi-Do)

  • 송유나;홍해근;권연옥 ;하진옥 ;김현지 ;손명진 ;박정화 ;권보연
    • 한국식품위생안전성학회지
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    • 제38권3호
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    • pp.184-191
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    • 2023
  • 견과류는 영양가가 우수하고 다양한 기능성 생리활성을 가져 건강한 식단에 중요한 요소이다. 멜라토닌은 뇌의 송과선에서 분비되는 호르몬으로 각종 조직의 산화적 손상을 방지하는 것으로 알려져 있으며, 식물체에서도 중요한 역할을 한다. 본 연구는 견과류의 멜라토닌 추출 및 정량을 위한 분석법을 마련하였고, 견과류의 높은 지방함량을 고려한 최적화된 추출 절차를 이용하여 경기도에서 유통되는 견과종실류 등의 멜라토닌 함량을 조사하였다. 땅콩 또는 견과류, 유지종실류 및 두류의 평균 멜라토닌 함량은 각각 1200.83(409.76-2223.56), 934.83 (454.10-1736.60), 616.46 (494.70-825.12) pg/g으로 나타났다. 호두와 밤의 경우 속껍질을 포함한 반탈각 상태와 과실만 있는 경우의 멜라토닌 함량을 비교한 결과, 반탈각 상태에서 멜라토닌 함량이 유의적으로 높았다. 또한 호두, 밤 및 땅콩의 경우 2022년 재배된 햇 견과보다 2021년 재배 후 저장된 견과에서 멜라토닌 함량이 유의적으로 높았다. 이러한 결과는 견과종실류 등의 멜라토닌 함량이 높아 우수한 기능성 식품임을 시사하였다.

야쿠티아의 동토지역에 서식하는 생물의 추운기후-순화의 조절에서 식물 지방산의 역할 (The Role of Plant Fatty Acids in Regulation of the Adaptation of Organisms to the Cold Climate in Cryolithic Zone of Yakutia)

  • 페트로프;두다레바;노크소로프;퍼크;세파로프;소프로노바;보이니코프;쥴푸가로프;이춘환
    • 생명과학회지
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    • 제26권5호
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    • pp.519-530
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    • 2016
  • 자연상태에서 녹색인 채로 눈에 덮여 있는 냉동사료 엽채식물은 초식동물의 생물활성물질과 영양분의 근원이 된다. 우리는 Avena sativa, Elytrigia repens, Equisetum variegatum과 Equisetum scirpoides의 잎에서 가을에 전체 지방산 함량이 상당히 증가함을 관찰하였다. 그러나, 여름에 채취한 잎에 비하여 눈에 덮혀 얼어있는 식물에서 지방산 불포화도의 증가는 없었다(북반부 온도최저점 지역에 서식하는 키가 작은 쇠뜨기인 E. scirpoides는 예외임). 야쿠티아 말의 내부 지방조직(젊은 말의 고기)에서, 18개의 지방산이 분석되었고, 그 중 10개가 포화 지방산이었다. 그 중 70%에 해당하는 양으로 단일불포화 올레산(С18:1(n-9))과 고도불포화 α-리놀렌산이 비슷하게 분포하였다. 내부 지방조직에 이렇게 많은 고도불포화 지방산이 많이 분포하는 것은 가을과 겨울에 먹인 녹색 먹이의 영향으로 본다. 우리는 야쿠티아 말의 조직에 상당한 양으로 분포하는 식물 특이적 지방산 함량은 이 말들이 오래 동안 저온 스트레스 상황에서 저항성을 가질 수 있은 조절기작에 중요한 역할을 한다고 제안한다.

플라이애시 첨가에 따른 세라믹 벽타일 소지의 물성변화 (Influence of Fly Ash Addition on Properties of Ceramic Wall Tiles)

  • 김진호;조우석;황광택;한규성
    • 한국재료학회지
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    • 제27권2호
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    • pp.76-81
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    • 2017
  • Recently, there have been many efforts to establish suitable processes for recycling fly ash, which is produced in thermal power plants and which poses serious environmental problems. Use of fly ash as a major ingredient of ceramic tiles can increase fly ash utilization, as well as reduce the cost of raw materials in ceramic tile production. In this study, the effects of fly ash addition on ceramic tile properties such as bending strength, water absorption and porosity were investigated. A manufacturing process of ceramic tile was developed for utilization of fly ash with high carbon content. In this approach, it is important to hold the ceramic tiles at a temperature that is sufficient for carbon oxidation, before the pores supplying oxygen to the inside of the ceramic tile are sealed. Ceramic wall tiles were manufactured with 0-40wt% of fly ash addition. The water absorption and porosity of the fired body were slightly changed with increasing fly ash content up to 30wt% and decreased with greater amounts of fly ash addition. The bending strength of ceramic tile including 10wt% fly ash increased, reaching a level comparable to that of ceramic tile without fly ash.

원자로냉각재계통 3" 분기관 용접부 위상배열초음파탐상검사(PAUT)기법 개발 (Development of the Phased Array Ultrasonic Test Technique for the Weld Inspection of Reactor Coolant System 3" Branch Connection Lines in Nuclear Power Plants)

  • 이승표;문용식;정남두;조용배;김창수
    • 한국압력기기공학회 논문집
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    • 제4권2호
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    • pp.40-45
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    • 2008
  • There exist many types of pipe and component fatigue through vibrations, thermal fatigues or shifting. In some cases of thermal stratification/thermal fatigue, pipes & components are receiving thermal stress by means of material expansion and shrinkage by continuous thermal repetitive variation. Small cracks initially occur on the inside surface by thermal stress. These cracks grow in depth the pipe wall and finally come to a rupture. Pipe parts of susceptibility to thermal stratification and thermal fatigue are now being examined by conventional UT(ultrasonic test) as volumetric examination. It is difficult to fully satisfy the code & standards requirements because 3" weldolet weldments of RCS 16" pipe to 3" branch connection lines have complex structural shape. To solve the problems of conventional UT examination, we made a realistic mock-up and UT calibration block. We performed a simulation of phased array UT utilizing CIVA as NDE(Non-Destructive Examination) simulation software. Also we designed phased array UT transducer and wedge, optimal frequency by using simulation data. We performed phased array UT experiment through mock-up including artificial flaws(notch). The phased array UT technique is finally developed to improve the reliability of ultrasonic test at RCS 16" pipe to 3" branch connection weld.

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