• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.425-426
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• 2002

The bone densitometer is to investigate the bone mineral content and density for the osteoporosis assessment by using dual energy X-ray photons. For the clinical verification of the ISOL's OSTEO plus, the clinical study was performed with healthy and non-menopausal 30 female volunteers. The fan-beam DXA machine (Lunar, Expert) was chosen as a reference. After correlation analysis of their bone mineral densities, a strong correlation was obtained. From the results, it is claimed that the new forearm bone densitometer is clinically useful in osteoporosis diagnosis.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.422-424
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• 2002

The accuracy of DXA(Dual Energy X-ray Absorptiometry) highly depends on the detection and separation capability of dual energy X-ray X-ray photons. In addition both of scan time and patient exposure are affected by detection efficiency. A CZT detector with a good energy resolution and high detection efficiency was evaluated for the application of bone densitometry. Its performance was compared to a photomultiplier tube with a NaI(T1) scintillator in terms of energy resolution, detection efficiency and the accuracy of bone mineral density measurement. The comparison study was performed with CZT detector and PM tube using DXA equipments(OSTEO Plus, OSTEO Prima, ISOL Technology). The energy spectrum was acquired using MCA(Multi-Channel Analyzer). The used X-ray energy ranged from 20keV to 86keV. The MCA result of the CZT detector showed a slightly sharper energy spectrum than that of NaI(T1). Detection efficiency of the CZT detector at 59.5keV was 1.4 times better. Remarkably the final results of bone mineral density measurements demonstrate only less than 1% difference. The CZT detector appears to have many benefits for the application of bone densitometry. Its excellent energy resolution can enhance the counting accuracy of dual energy X-ray spectrum. Furthermore its compactness in physical dimension and no cooling requirement will be additional benefits for a more compact and accurate bone densitometer.

• Progress in Medical Physics
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• v.18 no.3
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• pp.172-178
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• 2007

An ultrasonic bone densitometer has been developed by measuring speed of sound signal transmitted and received on the skin, not through the horizontal axis but through the vertical one in tissue. The SOS(speed of sound) method measuring the time difference between the ultrasound signals reflected from the both sides of surface of bone could produce more precise result compared with the BUA(broadband ultrasound attenuation) method measuring the frequency difference. Middle finger is selected to be the best measurement position in order to increase the accuracy, after due consideration that the thickness of flesh at the down part of thumb shows too much variation although the ratio of the receiving signal is higher than the other fingers. The measured value by using SOS method shows almost the same result as compared with the conventional DEXA method.

• Physical Therapy Korea
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• v.8 no.1
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• pp.51-58
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• 2001

In children with cerebral palsy, bone density is decreased by disturbance of bone remodelling due to lack of normal weight bearing and muscle contraction through physical activity. Loss of bone density cause fracture, delays treatment with immobilization, and leads to functional limitation. The purpose of this study was to investigate bone mineral density of lumbar spine in children with spastic quadriplegia and diplegia. Six spastic quadriplegia and 14 spastic diplegia were evaluated in this study. QDR 4500 X-ray densitometer was used to measure bone density at lumbar spine (L1~L4). Children with cerebral palsy showed lower bone density than that of normal children. Bone density in children with spastic quadriplegia and diplegia was $-1.812{\pm}.962$, $-1.519{\pm}.935$, respectively. However, there was no significant differences in bone density between children with spastic quadriplegia and diplegia. There was no significant difference in bone density relation to motor development level, height, and weight. Further study is needed to find the appropriate interventions for preventing loss of bone density in children with cerebral palsy.

• Journal of Korean Biological Nursing Science
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• v.15 no.4
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• pp.202-209
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• 2013

Purpose: The purpose of this study is to investigate relationships among sun-screening agents use, bone health promotion behavior, and bone mineral density. Methods: The participants of this study were 105 female college students. The data were collected using a questionnaire about sun-screening agent use and bone health promotion behavior. Bone mineral density was measured with Ultrasound Bone Densitometer/Osteo Pro Series. Data were analyzed with the SPSS/Win 18.0 program. Results: The mean Z-score in female college students was $-1.04{\pm}1.26$, and the T-score was $-1.16{\pm}1.22$, 21.39% of the participants have osteopenia. Bone mineral density showed a significant correlation with weight. Bone mineral density showed no significant correlation between sun-screening agent use, and bone health promotion behavior. There was a significant correlation between protection power of sun-screening agents and the protection by clothes. Conclusion: According to the results of this study, we need to develop an intervention program for bone health promotion of female college students.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.18 no.1
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• pp.13-25
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• 1988

Bone destruction was induced experimentally by the insertion of a bit of the arsenic compound into the pulp chambers of the right premolars and the artificial bone defects were produced in the periapical regions of the left premolars in 7 dogs. The serial standardized periapical radiographs using aluminum stepwedge attached to the XCP instruments, and resin bite blocks were taken following insertion of arsenic compound and at 2, 4, 7, 10, 14, 17, 21, 24 and 28 days in case of bone destruction and following bone injury and weekly thereafter for a total of 14 weeks in case of bone formation. The errors of the method were determined with error estimators described by the Duinkerke. All radiographs were evaluated by the visual examination after joint evaluation by three dental radiologists and analysed with densitometer. The following results were obtained; 1. Analysis of the bone destruction process 1) The error of the method in estimating two distances proved to be small (S.D. for the measuring error; 0.04㎜, S.D. for the over-all error; 0.06㎜, S.D. for the positioning error; 0.05㎜) 2) The radiographic changes were observed after 7 days in 6 cases, 4 days in 1 case and 10 days in 1 case by the visual examination. 3) Aluminum equivalent values were diminished after 2 days and the diminution of 0.58±0.19㎜ was demanded to be detected by the visual examination. 2. Analysis of the bone formation process 1) The error of the method in estimating two distances proved to be small (S.D. for the measuring error; 0.03㎜, S.D. for the over-all error; 0.04㎜ S.D. for the positioning error; 0.04㎜) 2) The radiographic changes were observed after 2 weeks in 5 cases and 3 weeks in 2 cases by the visual examination. 3) Aluminum equivalent values were increased after 1 week and the increase of 0.45±0.15㎜ was demanded to be detected by the visual examination. 4) Aluminum equivalent values were increased continuously for 7 or 9 weeks but there as only extremely small change after 10 weeks.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.17 no.1
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• pp.107-120
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• 1987

The purpose of this study was three-fold: to reexamine whether periapical and central lesions can be detected on the radiograph when they are in the cancellous bone, to investigate regianal differences in radiograph visualization of the lesion, and to. compare the interpretation of radiagraphs by densitometric analysis with the visual interpretation af the same radiographs. Forty-nine apical lesions and eighty-two central lesions were made in 8 mandibles and radiographed serially while being enlarged and deepened. All radiagraphs were evaluated by three dental radiologists. Each lesion was scored of 3 to 0, based on the radiographic appearances. Special radiographs of 15 apical and central lesions were analysed by densitometer and the results were compared with the scores which were previously assigned by three examiners. From this study the following conclusians could be drawn; 1. Experimental lesions confined to cancellous bone were detected an the radiagraphs in 41.3% of the cases. 2. Visualization of periapical lesions in cancellous bone was more apparent than that of central lesions in cancellous bone. 3. Visualization of the periapical lesions confined to. cancellous bane was highest in molar teeth, and detection of the central lesions in alveolar portion was easier than those in lower portion of mandibular body area. 4. It was possible to detect the experimental lesions without cortical plate involvement in 78.6% of the all lesions. 5. Densitometric analysis of radiographs could reproducibly distinguish bone changes, especially of central lesions in cancellous bone.

• Journal of the East Asian Society of Dietary Life
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• v.15 no.6
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• pp.655-662
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• 2005

Body content bone mined density and nutrient intake status of 129 college women in Daegu area are analyze4 The mean age was 23.1 years. Bone mineral density was measured in their right heel by SONOST-2000 ultrasound bone densitometer, and nutrient intake was assessed by a Questionnaire. Diet intake data were obtained by using a 24 hours recall method to evaluate the subject's usual diet. The average energy, Ca, Ee, Zn and folate intakes were 64.2, 47.5, 54.7, 62.9 and $57.4\%$ of RDA, respectively. Ca/P and Ca/Protein ratio were 0.46 and 6.7, respectively. The mean adequacy ratio(MAR), an index of overall dietary quality wag 0.6. The index of nutritional quality was under 1.0 for protein(0.7), vitamin A(0.9), E(0.7), $B_1(0.8)$, niacin(0.8), $B_6(0.6)$ and phosphorus(0.6). The less the protein and energy intake, the less the bone mineral density(p<0.05). The intakes of protein(p<0.05) and that of phosphorus(p<0.001) were positively correlated with bone quality index(BQI). The calcium intake was positively correlated with Z-score(p<0.05). The phosphorus intake was positively correlated with T-score(p<0.001) and Z-score(p<0.0001). In conclusion, this study indicates that nutrient intake of the college women is considerably lower than the RDA. Also the BQI is lower than standard.

• Environmental Analysis Health and Toxicology
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• v.21 no.1 s.52
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• pp.27-34
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• 2006

Numerous studies reported the significant association between genetic polymorphisms in the vitamin D receptor (VDR) gene and various bone phenotypes such as bone mineral density (BMD) and bone quality, although conflicting results were produced. The objective of this study was to investigate the association between a TaqI RFLP in the VDR gene and calcaneal BMD in Korean vegetarian men, and its interaction with nutrition status as an environmental factor. BUA (broadband ultrasound attenuation), SOS (sound of speed) and stiffness index of the calcaneus were measured using an ultrasound bone densitometer in 266 Korean men (age: $mean{\pm}SD;\;50.9{\pm}12.0$ year), and a TaqI RFLP in the VDR gene analysed by PCR-RFLP method. In total subjects, the distribution of TT, Tt and tt genotypes occurred with frequencies of 90.8%, 8.8% and 0.4%, respectively. There were no significant associations between this polymorphism and osteopenia-osteoporosis or several bone phenotypes in our subjects irrespectively of nutrition status (P>0.05). Therefore, our results suggest that a TaqI RFLP in the vitamin D receptor gene does not contribute to the susceptibility to the calcaneal BMD in Korean men.

• Journal of Radiation Industry
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• v.11 no.1
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• pp.27-31
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• 2017

Reliable follow-up of bone mineral density (BMD) by dual energy X-ray absorptiometry (DXA) is essential in clinical practice. When there is a difference in the BMD values from DXA systems in the same patient, cross calibration equation is required for the reliable follow-up. Unfortunately, no equation is existed in BMD measure between GE Lunar Prodigy Advance (US, GE Healthcare; LPA) and Osteosys Dexxum T (Korea, Osteosys; ODT) DXA systems. In this study, we evaluate the agreement of BMD values between LPA and ODT and suggest the cross calibration equation using European spine phantom (ESP) with two systems. We performed BMD measurements using ten scans with ESP in each DXA systems. We compared BMD values and calculated cross calibration equation by linear regression analysis. The comparison between the LPA and ODT bone densitometers used the ESP. Compared to the ESP BMD values, ODT underestimated 14.36% and LPA overestimated 12.96%. The average of total BMD measurement values acquired with ODT were 21.44% lower than those from LPA. Cross-calibration equation for LPA and ODT was derived from ESP. We calculated simple cross calibration equation for LPA and ODT DXA systems. Cross-calibration equation is necessary for the reliable follow-up of BMD values in two different systems.