• Journal of Korean Neurosurgical Society
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• 제29권6호
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• pp.826-831
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• 2000

The major indication of endoscope in neurosurgical field is intraventricular procedures. Recently, it can be used selectively in the intraaxial mass lesion associated cavity. For example, cystic mass, with liquefied necrosis, and blood clot can be approached with this technique. The authors present its usage in brain abscess ruptured into lateral ventricle. The neuroendoscope was introduced into abscess cavity through stereotactic guidance, the pus was then removed through continuous irrigation and suction under direct video visualization. The intraventricular pus was also cleaned through gentle, direct endoscopic irrigation and suction. The postoperative clinical course was uneventful. Brief overview is given for this intraaxial neuroendoscopic procedure.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제44권2호
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• pp.52-58
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• 2018

Dry socket, also termed fibrinolytic osteitis or alveolar osteitis, is a complication of tooth exodontia. A dry socket lesion is a post-extraction socket that exhibits exposed bone that is not covered by a blood clot or healing epithelium and exists inside or around the perimeter of the socket or alveolus for days after the extraction procedure. This article describes dry socket lesions; reviews the basic clinical techniques of treating different manifestations of dry socket lesions; and shows how microscope level loupe magnification of $6{\times}$ to $8{\times}$ or greater, combined with co-axial illumination or a dental operating microscope, facilitate more precise treatment of dry socket lesions. The author examines the scientific validity of the proposed causes of dry socket lesions (such as bacteria, inflammation, fibrinolysis, or traumatic extractions) and the scientific validity of different terminologies used to describe dry socket lesions. This article also presents an alternative model of what causes dry socket lesions, based on evidence from dental literature. Although the clinical techniques for treating dry socket lesions seem empirically correct, more evidence is required to determine the causes of dry socket lesions.

• 한국임상수의학회지
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• 제32권1호
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• pp.130-134
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• 2015

A 13-year-old, castrated male Yorkshire terrier was presented with acute blepharospasm 2 months after phacoemulsification with intraocular lens implantation in the left eye. Menace response was weakly positive in the left eye. Intraocular pressure (IOP) was 98 mmHg in the left eye. On ophthalmic examination using slit lamp biomicroscope, episcleral injection and corneal edema were observed in the left eye. Aqueous flare (1+) and iris bombe with peripheral anterior synechia were also detected in the left eye. In spite of medical treatments, IOP was remained more than 50 mmHg. Synechiolysis and radial iridectomy with irrigation/aspiration of anterior chamber were performed in the left eye. One week after the surgery, tissue plasminogen activator was injected to resolve the blood and fibrin clot in the left anterior chamber. Menace response was recovered completely 1 month after the surgery and IOP was maintained less than 20 mmHg more than 6 months.

• 대한수의학회지
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• 제22권2호
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• pp.233-237
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• 1982

Pathological studies on 6 milk goats administrated with urea were carried out to determine the effects of acute and chronic poisonings on the animal. Clinical signs appeared about 10 minutes after ingestion of the urea and they consisted chiefly in dullness, staggering, uncontrolled urination, dyspnea, frothy salivation, bloating, muscular tremor, humping of back and tetanic spasms. Macroscopic lesions were failure of blood clot, frothy and bloody contents in the highly congested respiratory tract, pulmonary edema, rumenitis and abomatitis accompanying with petechiation of the upper small intestine. Microscopically, the liver showed vacuolar degeneration, fatty change and areas of necrosis and partial proliferation of the interlobular connective tissues in chronic crises. The renal epithelium displaced vacuolar degeneration, necrosis and hyaline casts in their lumens. In the lungs, there were hyperemia, edema, hemorrhages, and acute catarrhal bronchitis. Neuronal degeneration and necrosis in the central nervous system, catarrhal rumenitis, abomatitis, doudenitis and myocardial hemorrhage were also demonstrated.

• 한국식생활문화학회지
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• 제9권5호
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• pp.489-497
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• 1995

The purpose of this study was to survey the various kinds of cooked beef products focusing on 'Chim' (a steamed beef products) through historical literatures written from 1670 to 1945 in korea. 'Chim' was recorded 25 times in the references and could be classified to 5 groups based on major ingredients such as stomach, intestine, lean meat, tail and ribs. Among the eleven cooked products of 'Chim', 'Kalbi-chim' (a steamed ribs) was recorded most frequently and 'Sundae-chim' (sausage-like product) was the next. Though 'Kalbi-chim' has been used untill present day but 'Sundae-chim' was disappeared in the early 19th centuries. Ribs were most popular ingredient among the major ingredients such as stomach, intestines, lean meat, tail, feet and ribs. Twenty one kinds of subingredients including pheasant meat, blood clot and flour were used for 'Chim'. Decorating ingredients such as roasted sesame power, pine nut and thin-layer fried eggs and seasonings such as pepper, roasted sesame powder, tripe, garlic, soy sauce and seasonings such as pepper, roasted sesame powder, tripe, garlic, soy sauce and sesame oil were used for 'Chim'.

• 대한수의사회지
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• 제20권5호
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• pp.314-317
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• 1984

장결석증으로 폐사한 경주말의 병리학적 소견과 이들의 발생기전을 기술하였다. 임상적으로는 선통, 식욕부진, 하리, 횡와 및 허탈을 주증으로 하였고, 육안적으로는 혈액응고불양, 복막염, 각종 장기의 충출혈과 소결장의 기시부를 직경 14.4cm의 광물성 결석이 폐쇄하고 있는 것을 볼 수 있었으며, 상부대결장에서는 확장과 천공이 인정되었다. 현미경적 소견으로는 간장, 신장 및 부신의 변성괴사, 산재성 혈전, 폐수종, 그리고 대결장에서 습성괴저를 관찰할 수 있었다. 이상의 소견들은 장벽의 빈혈성괴사 및 괴저, 그리고 복막염 등에 기인하는 자가중독성 및 내독소성 독혈증에 의한 것이라고 생각된다.

• Journal of Rhinology
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• 제25권2호
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• pp.118-122
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• 2018

Epithelioid hemangioendothelioma is a rare vascular tumor with intermediate malignity and metastasis risk. It presents epithelioid cells with intracytoplasmic vacuoles and low mitotic activity. Its vascular nature can be confirmed by immunohistochemical studies (vimentin, CD31, CD34, and factor VIII). It is extremely rare in the nasal cavity, with only one case reported on the middle turbinate in Korea. The authors present a case of epithelioid hemangioendothelioma on the choana with a size of 2mm, which easily coult have been misdiagnosed as a blood clot.

• 대한소아치과학회지
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• 제25권4호
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• pp.843-848
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• 1998

Pulpotomy is a frequently used treatment modality in primary teeth. It is method by which infected coronal pulp is removed while retaining vital radicular pulp. Since its introduction in 1930 by Sweet formocresol remains the most popular medicament for this treatment. However, despite its outstanding bactericidal properties, formocresol is known to cause adverse tissue reactions. Theoretically, formocresol disinfects and fixes radicular pulp and thus prevents infection and internal resorption. In reality, however, it leads to chronic inflammation and is sometimes responsible for failures through abscess formation and internal root resorption. Also, Myers et al., in 1978, reported on the systemic distribution of FC and other studies have followed with reports of its immunological, mutagenic and carcinogenic effects. Much effort has, therefore, focused on the development of alternative medicaments and techniques. Since its introduction in 19C, ferric sulfate proven itself as an effective hemostatic agent and is used as an astringent in dentistry. In 1988, Landau and Johnsen suggested ferric sulfate be used as a medicament in pulpotomy and many studies have focused on it to overcome the toxic effects of FC. Ferric sulfate acts through its ferric ion and iron ion, which react with blood protein leading to aggregation. The aggregated protein acts to plug the blood vessels, causing mechanical hemostasis. As blood clot formation is minimal, there is reduced inflammation of radicular pulp and enhanced healing. There are no reports regarding its systemic distribution. This is a report of cases treated by the author using pulpotomy with ferric sulfate.

• Journal of Chest Surgery
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• 제32권1호
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• pp.92-95
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• 1999

폐엽 절제술후 발생한 지속적인 공기 누출 환자에 있어서 현재 화학적 늑막유착술이 보편적으로 시행되고 있으며, 여기에 쓰이는 늑막유착제로는 talc, tetracyclin, doxycyclin, bleomycin, vibramycin, OK432 등이 있다. 그러나 재팽창이 불완전하여 사강이 남아있는 경우 화학적 늑막유착술 만으로는 그 효과를 기대하기 어려우며, 장기간 흉관을 가지고 있어야 함으로 농흉의 위험성도 증가한다. 따라서 폐절제술 혹은 늑막박피술후 발생한 지속적인 공기누출은 많은 흉부외과 의사의 고민이었다. 자가혈을 이용한 늑막유착술은 이러한 지속적 공기누출에 대한 해결법의 하나로 개발되었으며, 그 기전은 혈괴가 직접 기관지 늑막루를 폐쇄하면서 동시에 사강을 감소시킴으로서 늑막유착을 유발하는 것으로 생각된다. 본원에서는 폐수술후 지속적인 공기누출 2례에서 자가혈과 OK432 그리고 자가혈과 vibramycin을 각각 사용하여 좋은 결과를 얻었다.

• BMB Reports
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• 제29권6호
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• pp.500-506
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• 1996

We have isolated a water-extracted novel regulator for blood coagulation from an earthworm, Lumbricus rubellus. As a folk remedy, the earthworm has been known to facilitate blood circulation. After complete heat inactivation of endogenous proteases in the earthworm, an anticoagulant(s) was purified through ammonium sulfate fractionation and three consecutive gel permeation chromatography of Sephacryl S-300, Sephadex G-75, and G-150 by measuring activated partial thromboplastin time (APTT) The anticoagulant was further purified to 2,800 fold with a C4 reversed-phase HPLC This activity was stable under heat ($100^{\circ}C$ for 30 min) and acidic conditions (0.4 N HCl). The effects of this partially purified anticoagulant on thrombin were observed with various substrates such as N${\alpha}$-benzoyl-DL-arginine-p-nitroanilide (BApNA), H-D-phenylalanyl-L-pipecoyl-L-arginine-p-nitroanilide (S-2238), N${\alpha}$-p-tosyl-L-arginine methyl ester (TAME), and fibrinogen as a natural substrate. Only TAME hydrolysis, due to an esterase activity of the enzyme, was inhibited among the chromogenic substrates. In addition, the anticoagulant not only inhibited the conversion of fibrinogen to fibrin but also prolonged the fibrin clot formation monitored with the in vitro coagulation test. Based on these observations, we suggest the significance of measuring the ability of antithrombotic drugs to inhibit the esterase activity of thrombin. In this report, it was also shown that the earthworm indeed contained a water-extractable, heat- and acid-stable anticoagulant which could be used as a novel antithrombotic agent.