DOI QR코드

DOI QR Code

A Case of Epithelioid Hemangioendothelioma on the Choana

후비공에 발생한 상피모양 혈관내피종 1예

  • Sohn, Jung Heob (Departments of Otorhinolaryngology-Head and Neck Surgery, Sanggye Paik Hospital, College of Medicine, Inje University) ;
  • Cho, Kyoung Rai (Departments of Otorhinolaryngology-Head and Neck Surgery, Sanggye Paik Hospital, College of Medicine, Inje University)
  • 손정협 (인제대학교 의과대학 상계백병원 이비인후과학교실) ;
  • 조경래 (인제대학교 의과대학 상계백병원 이비인후과학교실)
  • Received : 2017.10.19
  • Accepted : 2018.08.25
  • Published : 2018.11.30

Abstract

Epithelioid hemangioendothelioma is a rare vascular tumor with intermediate malignity and metastasis risk. It presents epithelioid cells with intracytoplasmic vacuoles and low mitotic activity. Its vascular nature can be confirmed by immunohistochemical studies (vimentin, CD31, CD34, and factor VIII). It is extremely rare in the nasal cavity, with only one case reported on the middle turbinate in Korea. The authors present a case of epithelioid hemangioendothelioma on the choana with a size of 2mm, which easily coult have been misdiagnosed as a blood clot.

Keywords

References

  1. Weiss SW, Enzinger FM. Epithelioid hemangioendothelioma: a vascular tumor often mistaken for a carcinoma. Cancer 1982;50(5):970-81. https://doi.org/10.1002/1097-0142(19820901)50:5<970::AID-CNCR2820500527>3.0.CO;2-Z
  2. Bollinger BK, Laskin WB, Knight CB. Epithelioid hemangioendothelioma with multiple site involvement. Literature review and observations. Cancer 1994;73(3):610-5. https://doi.org/10.1002/1097-0142(19940201)73:3<610::AID-CNCR2820730318>3.0.CO;2-3
  3. Yang YJ, Kim YB, Kim SB, Sohn JH. A case of hemangioendothelioma on the nasal septum. Korean J Otorhinolaryngol-Head Neck Surg 2001;44(11):1220-3.
  4. Kim EH, Yoon MH, Yeo NK. A case of epithelioid hemangioendothelioma of the nasal cavity. Korean J Otorhinolaryngol-Head Neck Surg 2016;59(3):242-5. https://doi.org/10.3342/kjorl-hns.2016.59.3.242
  5. O'Hara CD, Nascimento AG. Endothelial lesions of soft tissues: a review of reactive and neoplastic entities with emphasis on low-grade malignant ("borderline") vascular tumors. Adv Anat Pathol 2003;10(2):69-87. https://doi.org/10.1097/00125480-200303000-00002
  6. Albuquerque AKAC, Romano SO, Eisenberg ALA. Epithelioid hemangioendothelioma: 15 years at the national cancer institute. literature review. J Bras Patol Med Lab 2013;49(2):119-25. https://doi.org/10.1590/S1676-24442013000200007
  7. Semino L, Pagella F, Delu G, Todeschini A, Luinetti O, Zappoli F, et al. Endoscopic treatment of ethmoidal hemangioendothelioma: case report and review of the literature. Am J Otolaryngol 2006;27(4):287-90. https://doi.org/10.1016/j.amjoto.2005.11.006
  8. Ellis GL, Kratochvil FJ 3rd. Epithelioid hemangioendothelioma of the head and neck: a clinicopathologic report of twelve cases. Oral Surg Oral Med Oral Pathol 1986;61(1):61-8. https://doi.org/10.1016/0030-4220(86)90204-5
  9. Gordon-Nunez MA, Silva eM, Lopes MF, de Oliveira-Neto SF, Maia AP, Galvao HC. Intraoral epithelioid hemangioendothelioma: a case report and review of the literature. Med Oral Patol Oral Cir Bucal 2010;15(2):340-6.
  10. Sardaro A, Bardoscia L, Petruzzelli MF, Portaluri M. Epithelioid hemangioendothelioma: an overview and update on a rare vascular tumor. Oncol Rev 2014;8(2):82-91.
  11. Patel NR, Salim AA, Sayeed H, Sarabia SF, Hollingsworth F, Warren M, et al. Molecular characterization of epithelioid hemangioendotheliomas identifies novel WWTR1-CAMTA1 fusion variants. Histopathology 2015;67(5):699-708. https://doi.org/10.1111/his.12697
  12. Perkins P, Weiss SW. Spindle cell hemangioendothelioma: an analysis of 78 cases with reassessment of its pathogenesis and biological behavior. Am J Surg Pathol 1996;20:1196-204. https://doi.org/10.1097/00000478-199610000-00004
  13. Mentzel T, Beham A, Calonje E, Katenkamp D, Fletcher CD. Epithelioid hemangioendothelioma of skin and soft tissues: clinicopathologic and immunohistochemical study of 30 cases. Am J Surg Pathol 1997;21(4):363-74. https://doi.org/10.1097/00000478-199704000-00001
  14. Dail DH, Liebow AA, Gmelich JT, Friedman PJ, Miyai K, Myer W, et al. Intravascular, bronchiolar, and alveolar tumor of the lung (IVBAT). An analysis of twenty cases of a peculiar sclerosing endothelial tumor. Cancer 1983;51(3):452-64. https://doi.org/10.1002/1097-0142(19830201)51:3<452::AID-CNCR2820510317>3.0.CO;2-M
  15. Girolamo Di, Giacomini PG, Coli A, Castri F, Padova AD, Bigotti G. Epithelioid haemangioendothelioma arising in the nasal cavity. J Laryngol Otol 2003;117(1):75-77. https://doi.org/10.1258/002221503321046711
  16. Resnik KS, Kantor GR, Spielvogel RL, Ryan E. Cutaneous epithelioid hemangioendothelioma without systemic involvement. Am J Dermatopathol 1993;15(3):272-6. https://doi.org/10.1097/00000372-199306000-00015
  17. Yoon SW, Park MJ, Kim KH, Ko BJ, Kim CK, Sohn JH. Early endoscopic electrocoagulation of the sphenopalatine artery for refractory posterior epistaxis: preliminary study. J Rhinol 2014;21(2):112-8.
  18. Kim SW, Lee MH, Maeng CH, Yun DG, Kim CD. Clinical analysis of epistaxis: result of the recent 10 years. Korean J Otorhinolaryngol-Head Neck Surg 2000;43(11):1216-21.
  19. Zhang X, Wang EW, Wei H, Shi J, Snyderman CH, Gardner PA, et al. Anatomy of the posterior septal artery with surgical implications on the vascularized pedicled nasoseptal flap. Head Neck 2015;37(10):1470-6. https://doi.org/10.1002/hed.23775

Cited by

  1. Epithelioid Hemangioendothelioma Arising in Nasal Cavity : A Case Report vol.30, pp.1, 2018, https://doi.org/10.35420/jcohns.2019.30.1.100