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The Electroconvulsive Therapy in the Prevention of Suicide Risks and Attempts (자살 위험성 및 자살 시도 방지에 대한 전기경련치료의 역할)

  • Kim, Hee Cheol;Jeong, Seong Hoon;Ahn, Yong Min;Park, Seung Hyun;Kim, Yong Sik;Chung, In Won
    • Korean Journal of Biological Psychiatry
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    • v.27 no.2
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    • pp.64-73
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    • 2020
  • Suicidality is the most serious complication of mood disorders and psychosis; effective treatment should reduce suicide rates. The Organization for Economic Cooperation and Development age-standardized suicide rate in Korea was 22.6 in 2018, much higher compared to other countries worldwide. As mental and psychiatric problems are the main reasons for suicide attempts, accounting for 31.6% in 2018, targeting such problems should be the focus of efforts to reduce suicide rates. However, the ability of current pharmacotherapeutic and psychotherapeutic interventions to reduce suicide rates is limited due to their delayed effects. Therefore, electroconvulsive therapy (ECT) has been proposed as an alternative treatment. This approach is effective for treating most mental disorders associated with high suicide rates, including severe depression, bipolar disorder, and intractable psychotic disorders; ECT is also effective for Parkinson's disease, which has the highest suicide rate among all disorders in Korea. The acute, long-term, and prophylactic effects of ECT on suicidality have been reported in the literature, and treatment guidelines outside of Korea recommend that ECT be used at an early stage for rapid reduction of suicide rates, as opposed to being applied as a treatment of last resort. However, only ~0.092 of every 10000 members of the Korean general population received ECT in 2018; this is much lower than the average rate worldwide, of 2.2 per 10000. Elimination of obstacles to the use of ECT, early crisis intervention involving administration of ECT for rapid stabilization, and maintenance ECT to prevent recurrence should reduce suicide rates.

Triggered Electrooculography for Identification of Oculomotor and Abducens Nerves during Skull Base Surgery

  • Jeong, Ha-Neul;Ahn, Sang-Il;Na, Minkyun;Yoo, Jihwan;Kim, Woohyun;Jung, In-Ho;Kang, Soobin;Kim, Seung Min;Shin, Ha Young;Chang, Jong Hee;Kim, Eui Hyun
    • Journal of Korean Neurosurgical Society
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    • v.64 no.2
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    • pp.282-288
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    • 2021
  • Objective : Electrooculography (EOG) records eyeball movements as changes in the potential difference between the negatively charged retina and the positively charged cornea. We aimed to investigate whether reliable EOG waveforms can be evoked by electrical stimulation of the oculomotor and abducens nerves during skull base surgery. Methods : We retrospectively reviewed the records of 18 patients who had undergone a skull base tumor surgery using EOG (11 craniotomies and seven endonasal endoscopic surgeries). Stimulation was performed at 5 Hz with a stimulus duration of 200 μs and an intensity of 0.1-5 mA using a concentric bipolar probe. Recording electrodes were placed on the upper (active) and lower (reference) eyelids, and on the outer corners of both eyes; the active electrode was placed on the contralateral side. Results : Reproducibly triggered EOG waveforms were observed in all cases. Electrical stimulation of cranial nerves (CNs) III and VI elicited positive waveforms and negative waveforms, respectively, in the horizontal recording. The median latencies were 3.1 and 0.5 ms for craniotomies and endonasal endoscopic surgeries, respectively (p=0.007). Additionally, the median amplitudes were 33.7 and 46.4 μV for craniotomies and endonasal endoscopic surgeries, respectively (p=0.40). Conclusion : This study showed reliably triggered EOG waveforms with stimulation of CNs III and VI during skull base surgery. The latency was different according to the point of stimulation and thus predictable. As EOG is noninvasive and relatively easy to perform, it can be used to identify the ocular motor nerves during surgeries as an alternative of electromyography.

Review of Carbon Materials Used in Fuel cell Components (연료 전지 구성요소에 사용되는 탄소 재료에 관한 고찰)

  • Jang, Min-Hyeok;Kang, Yu-Jin;Jo, Hyung-Kun;Park, Cho-I;Sim, Hye-Soo;Park, Joo-Il
    • Journal of the Korea Convergence Society
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    • v.12 no.2
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    • pp.193-200
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    • 2021
  • As the degree of environmental pollution caused by the use of fossil fuels intensifies, many countries continue to invest in the development of alternative energy. PEMFC, one of the alternative energies, consists of four main components: bipolor plate, electrolyte, gas diffusion layer, and electrode. Among them, bipolor plate, the gas diffusion layer, and electrode are generally manufactured using carbon materials such as carbon black and carbon fiber. These carbon materials are expensive in manufacturing process or have disadvantages such as corrosion, and research is being conducted in many fields to improve this. This paper collects several research results conducted to improve the shortcomings of these three components and examines the trends of PEMFC by grasping what problems have been and how they have improved.

A Study on SCR-based ESD Protection Circuit with High Holding Voltage and All-Direction Characteristics (높은 Holding Voltage 및 All-Direction 특성을 갖는 SCR 기반의 ESD 보호회로에 관한 연구)

  • Jin, Seung-Hoo;Do, Kyoung-Il;Woo, Je-Wook;Koo, Yong-Seo
    • Journal of IKEEE
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    • v.24 no.4
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    • pp.1156-1161
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    • 2020
  • In this paper, we propose a new ESD protection circuit with improved electrical characteristics through structural changes of the existing one-way SCR. The proposed ESD protection circuit has high holding voltage characteristics due to the inserted N+ floating and P+ floating regions, and thus the latch-up immunity characteristics are improved. In addition, structural change enables ESD discharge in four types of Zapping mode (PD, PS, ND, NS), and has superior area efficiency than unidirectional SCR. In addition, the P+ floating and N+ floating lengths corresponding to the base length of the parasitic bipolar transistor, and the distance between P+ floating and N+ floating were designated as design variables, and the high holding voltage was verified through Synopsys' TCAD Simulator.

Metal Foam Flow Field Effect on PEMFC Performance (금속 폼 유로가 고분자전해질 연료전지 성능에 미치는 영향)

  • Kim, Junseob;Kim, Junbom
    • Applied Chemistry for Engineering
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    • v.32 no.4
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    • pp.442-448
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    • 2021
  • Flow field is an important parameter for polymer electrolyte membrane fuel cell (PEMFC) performance to have an effect on the reactant supply, heat and water diffusion, and contact resistance. In this study, PEMFC performance was investigated using Cu foam flow field at the cathode of 25 cm2 unit cell. Polarization curve and electrochemical impedance spectroscopy were performed at different pressure and relative humidity conditions. The Cu foam showed lower cell performance than that of serpentine type due to its high ohmic resistance, but lower activation and concentration loss due to the even reactant distribution of porous structure. Cu foam has the advantage of effective water transport because of its hydrophobicity. However, it showed low membrane hydration at low humidity condition. The metal foam flow field could improve fuel cell performance with a uniform pressure distribution and effective water management, so future research on the properties of metal foam should be conducted to reduce electrical resistance of bipolar plate.

Robust Design for Parts of Induction Bolt Heating System (유도가열시스템의 구성부품에 대한 강건설계)

  • Kim, Doo Hyun;Kim, Sung Chul;Lee, Jong Ho;Kang, Moon Soo;Jeong, Cheon Kee
    • Journal of the Korean Society of Safety
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    • v.36 no.2
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    • pp.10-17
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    • 2021
  • This paper presents the robust design of each component used in the development of an induction bolt heating system for dismantling the high-temperature high-pressure casing heating bolts of turbines in power plants. The induction bolt heating system comprises seven assemblies, namely AC breaker, AC filter, inverter, transformer, work coil, cable, and CT/PT. For each of these assemblies, the various failure modes are identified by the failure mode and effects analysis (FMEA) method, and the causes and effects of these failure modes are presented. In addition, the risk priority numbers are deduced for the individual parts. To ensure robust design, the insulated-gate bipolar transistor (IGBT), switched-mode power supply (SMPS), C/T (adjusting current), capacitor, and coupling are selected. The IGBT is changed to a field-effect transistor (FET) to enhance the voltage applied to the induction heating system, and a dual-safety device is added to the SMPS. For C/T (adjusting current), the turns ratio is adjusted to ensure an appropriate amount of induced current. The capacitor is replaced by a product with heat resistance and durability; further, coupling with a water-resistant structure is improved such that the connecting parts are not easily destroyed. The ground connection is chosen for management priority.

Evaluation of the efficacy of unipolar and bipolar spinal dorsal root ganglion radiofrequency thermocoagulation in the treatment of postherpetic neuralgia

  • Zhu, Jianjun;Luo, Ge;He, Qiuli;Yao, Ming
    • The Korean Journal of Pain
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    • v.35 no.1
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    • pp.114-123
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    • 2022
  • Background: Different views have been proposed on the radiofrequency treatment modes and parameters of radiofrequency thermocoagulation of the spinal dorsal root ganglion for the treatment of postherpetic neuralgia (PHN). It is urgent to identify a more effective therapy for patients with PHN. Methods: Patients who underwent radiofrequency thermocoagulation therapy for PHN were retrospectively reviewed and were divided into a radiofrequency thermocoagulation (CRF) and double neddles radiofrequency thermocoagulation (DCRF). The pain scores (numerical rating scale, NRS) were evaluated at the following time points: before the operation, 1 day, 3 months, 6 months, 1 year, and 2 years after operation. The incidence of complications and the degree of pain relief were evaluated. The in vitro ovalbumin experiment was used to indicate the effects of radiofrequency thermocoagulation. Results: Compared with the preoperative NRS scores, the postoperative NRS scores decreased significantly; the NRS scores of the DCRF group was lower than that of the CRF group at all time points from 6 months to 2 years following the operation. The total effective rate of the DCRF group was significantly higher than that of the CRF group at 2 years following the operation. The incidence of numbness in the DCRF group was higher than that noted in the CRF group. The ovalbumin experiments in vitro indicated that the effects of radiofrequency thermocoagulation were optimal when the distance between the two needles was 5 mm. Conclusions: DCRF with a 5 mm spacing exhibits a longer duration and higher effective rate in the treatment of PHN and is worth promoting.

Technical Evaluation of Engineering Model of Ultra-Small Transmitter Mounted on Sweetpotato Hornworm

  • Nakajima, Isao;Muraki, Yoshiya;Mitsuhashi, Kokuryo;Juzoji, Hiroshi;Yagi, Yukako
    • Journal of Multimedia Information System
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    • v.9 no.2
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    • pp.145-154
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    • 2022
  • The authors are making a prototype flexible board of a radio-frequency transmitter for measuring an electromyogram (EMG) of a flying moth and plan to apply for an experimental station license from the Ministry of Internal Affairs and Communications of Japan in the summer of 2022. The goal is to create a continuous low-dose exposure standard that incorporates scientific and physiological functional assessments to replace the current standard based on lethal dose 50. This paper describes the technical evaluation of the hardware. The signal of a bipolar EMG electrode is amplified by an operational amplifier. This potential is added to a voltage-controlled crystal oscillator (27 MHz, bandwidth: 4 kHz), frequency-converted, and transmitted from an antenna about 10 cm long (diameter: 0.03 mm). The power source is a 1.55-V wristwatch battery that has a total weight of about 0.3 g (one dry battery and analog circuit) and an expected operating time of 20 minutes. The output power is -7 dBm and the effective isotropic radiated power is -40 dBm. The signal is received by a dual-whip antenna (2.15 dBi) at a distance of about 100 m from the moth. The link margin of the communication circuit is above 30 dB within 100 m. The concepts of this hardware and the measurement data are presented in this paper. This will be the first biological data transmission from a moth with an official license. In future, this telemetry system will improve the detection of physiological abnormalities of moths.

Dissociative Identity Disorder in an Adolescent With Nine Alternate Personality Traits: A Case Study

  • Lee, Sang-Hun;Kang, Na Ri;Moon, Duk-Soo
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.33 no.3
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    • pp.73-81
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    • 2022
  • Since dissociative identity disorder (DID) has symptoms similar to schizophrenia, such as auditory hallucinations and delusional thoughts of being controlled, there are difficulties in its differential diagnosis. A 16-year-old adolescent male patient who was previously diagnosed with schizophrenia from a different hospital was admitted to our inpatient psychiatric unit for the evaluation of auditory hallucinations and suicide attempts. Through psychiatric evaluations, it was determined that the patient suffered from identity alternation, dissociation, and amnesia. As for the diagnostic evaluations, the following measures were implemented: a psychiatric interview regarding the diagnostic criteria, mental status examination, laboratory tests, brain imaging studies, electroencephalography, and full psychological test for adolescents, and the self-reported measure of the Adolescent Dissociative Experiences Scale. The patient was diagnosed with DID, and the following treatments were administered: pharmacotherapy, ego state therapy, psychoeducation regarding emotions, trauma-focused psychotherapy including stabilization, and family therapy. Following treatment, in the internal dimensions, the patient was able to recognize the nine alternate identities in charge of his emotions, which established a basis for the potential integration of identities. In the external dimensions, he showed improvements in the aspects of family conflicts and issue of school refusal. This is the first reported case of DID in an adolescent in Korea; it emphasizes the consideration of DID in the differential diagnosis of other mental illnesses such as schizophrenia, bipolar disorder, and posttraumatic stress disorder and expands the treatment opportunities for DID by sharing the procedures of ego state therapy.

Anti-LGI1 Antibody Encephalitis (양극성장애로 오인된 LGI1 자가면역성뇌염)

  • Kim, Eun Soo;Lee, HeeJun;Jeon, Sang Won;Cho, Sung Joon
    • Korean Journal of Biological Psychiatry
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    • v.27 no.2
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    • pp.112-116
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    • 2020
  • Leucine rich glioma inactivated (LGI1) encephalitis is an uncommon neurological disorder rarely encountered in clinical practice. However, it is a potentially fatal autoimmune syndrome that can decrease the level of consciousness, possibly progressing to coma. Additionally, unless diagnosed and promptly treated, it can cause permanent cognitive impairment. Since LGI1 encephalitis can initially present with psychiatric symptoms, there can be delays in reaching a proper diagnosis. This report describes a case of a 47-year-old woman with LGI1 antibodies-associated limbic encephalitis who initially presented with psychosis. Her blood tests were normal and no MRI and EEG abnormalities were found. Cerebrospinal fluid analysis was negative for other possible infectious causes. Three months after admission, she was found to be LGI1 antibody positive. LGI1 encephalitis should be suspected in patients with symptoms such as memory loss, confusion, seizures, and psychiatric symptoms. Prompt diagnosis and treatment of LGI1 encephalitis are warranted because prognosis becomes worse when such actions are delayed.