• 제목/요약/키워드: beta regression model

검색결과 241건 처리시간 0.025초

Development of a food-based index of dietary inflammatory potential for Koreans and its relationship with metabolic syndrome

  • Na, Woori;Yu, Tae Yang;Sohn, Cheongmin
    • Nutrition Research and Practice
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    • 제13권2호
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    • pp.150-158
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    • 2019
  • BACKGROUND/OBJECTIVES: Inflammation is known to be a risk factor for metabolic diseases. This study aimed to develop a Food-based Index of Dietary Inflammatory Potential (FBDI) and examine its association with metabolic biomarkers. SUBJECTS/METHODS: This study analyzed the raw data from the 2012-2014 Korean Genome and Epidemiology Study data of 17,771 people. To analyze the relationship between foods consumed by Koreans and inflammation, we conducted a correlation analysis between 51 food groups and hs-CRP levels. The FBDI was developed from 17 food groups selected by multiple regression method. We examined whether FBDI was associated with metabolic markers (waist circumference, blood pressure, fasting glucose, triglyceride, and HDL-cholesterol) in the 6th Korea National Health and Nutrition Examination Survey (KNHANES). We used binary logistic regression analysis to examine the association. RESULTS: The FBDI model included seven of the anti-inflammatory food groups and three of the pro-inflammatory food groups. The FBDI formula was calculated by multiplying the intake of food group by ${\beta}$-coefficients derived from the multiple regression model based on the correlation analysis. The FBDI was significantly associated with waist circumference (P < 0.001), blood pressure (P < 0.001), triglyceride level (P < 0.001), and HDL-cholesterol (P < 0.001) level among adults aged 20-64 years in the KNHANES. The prevalence of metabolic syndrome was 2.618 times higher in the group with the highest FBDI than in the group with the lowest one (95% confidence interval: 1.778-3.856, P for trend < 0.001). CONCLUSIONS: This study established an FBDI reflecting food intake patterns of Koreans, which showed a significant relationship with the prevalence of metabolic syndrome.

베타 2-아드레날린 수용체의 유전자 변이형이 비만도에 미치는 영향 (Effects of ${\beta}2-Adrenergic$ Receptor Polymorphism on Obesity)

  • 김길수;오현희;최선미;양현성;배정환;윤유식
    • 한방비만학회지
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    • 제3권1호
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    • pp.7-16
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    • 2003
  • Objectives : The lipolytic effects of catecholamines in adipose tissue are mediated by members of adrenergic receptors. This study was conducted to examine the effects of ${\beta}2-AR$ Gln27Glu (Q27E) polymorphism on obesity indices and risk among obesity clinic patients. Methods : 532 subjects, 38 men and 494 women, who attended a weight loss program in a local obesity clinic were analyzed. Height, weight, BMI, WHR and obesity index were measured or calculated. Body composition was measured by bio-impedance analysis. Genotype of ${\beta}2-AR$ polymorphism in codon 27 was analyzed by PCR-RFLP method. Serum concentrations of fasting glucose, total and HDL cholesterol, and triglyceride were determined by autobiochemical analyzer. Results: The Genotype distributions of ${\beta}2-AR$ gene were QQ type 81.3%, QE type 17.9% and EE type 8%. Therefore, the frequency of E allele of ${\beta}2-AR$ gene was 0.170 in the total subjects. The frequency of the ${\beta}2-AR$ variant genotype(QE+EE) was significantly higher in obese group($BMI{\geqq}25$) compared with non-obese group(p=0.027). Weight was significantly higher in variant(QE+EE) type compared with normal(QQ) type in total subjects(p=0.001), male(p=0.022) and female(p=0.013). BMI, obesity index and WHR were also significantly higher in QE+EE type. Body fat man was significantly higher in QE+EE type in total subjects(p=0.005) and female(p=0.027). When forward stepwise regression analysis was used to create a model of risk predictors of obesity($BMI{\geqq}25$), QE+EE type of ${\beta}2-AR$ gene was found to be a significant risk factor for obesity (p=0.042, ORs 1.597). Conclusions: QE+EE genotype of ${\beta}2-AR$ was associated with increased obesity indices and might be a significant risk factor for obesity.

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노인 구강건조증에 대한 음허 진단의 유용성 및 주관적 구강건조감의 영향요인 : 전향적 단면 조사 연구 (Availability of Diagnosis of Yin-deficiency in Elderly People with Xerostomia and Factors Influencing Subjective Oral Dryness: A Prospective Cross-sectional Study)

  • 김주연;김진성;박재우;류봉하
    • 대한한의학회지
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    • 제34권3호
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    • pp.13-24
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    • 2013
  • Objectives: The aims of this study were to investigate the availability of diagnosis of Yin-deficiency in the elderly with xerostomia and factors influencing subjective oral dryness. Methods: We surveyed 50 patients recruited by the clinical trial, 'Efficacy of Yukmijihwang-tang on Xerostomia in the Elderly: A Randomized, Double-blind, Placebo-controlled, Two-center Trial'. The subjects were assessed on their subjective oral dryness using the Dry Mouth Symptom Questionnaire (DMSQ). Their salivary functions were measured by Unstimulated Salivary Flow Rate (USFR) measurements. In addition, the subjects were evaluated on their Qi-stagnation and Yin-deficiency conditions using the Qi-stagnation questionnaire and Yin-deficiency questionnaire. Results: There were statistically significant correlations between three variables (USFR, DMSQ score and Qi-stagnation score) and Yin-deficiency score. In the multiple regression analysis, the regression model was statistically significant (F = 10.273, p < .001). The factor most strongly influencing the subjective oral dryness was USFR (${\beta}$ = -0.386). Yin-deficiency had the next strongest impact on the subjective oral dryness (${\beta}$ = 0.371). Qi-stagnation affected the subjective oral dryness weakly (${\beta}$ = 0.075). In the simple regression analysis, Yin-deficiency had a statistically significant effect on each of six subscales of DMSQ (p < .01). Among the six subscales, DMSQ-1 ('Oral dryness at night or on awakening') was the most strongly influenced by Yin-deficiency. Conclusions: The results of this study show that the diagnosis of Yin-deficiency in the elderly with xerostomia was available and Yin-deficiency was an important factor influencing the subjective oral dryness. Therefore, the consideration of Yin-deficiency is significant for diagnosis and treatment in the elderly with xerostomia.

남자 흡연 대학생의 금연 자기효능감, 우울 및 사회적 지지가 니코틴 의존도에 미치는 영향 (Influence of Self- efficacy for Smoking Cessation, Depression, Social Support and Nicotine Dependency in the College Male Smoker)

  • 이지은;이정화;홍주영
    • 디지털융복합연구
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    • 제15권6호
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    • pp.249-258
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    • 2017
  • 본 연구는 남자 흡연 대학생의 금연 자기효능감, 우울 및 사회적지지가 니코틴 의존도에 미치는 영향을 파악하기 위한 서술적 조사연구이다. 경북지역 2개 대학교 남학생 149명 대상으로 2016년 9월 7일~18까지 설문조사 하였고, SPSS 22.0을 사용해 서술통계, t-test, ANOVA, Pearson correlation, multiple regression으로 분석하였다. 남자 흡연 대학생의 일반적 특성 및 흡연관련 특성 중 학년 및 전공계열에 따라 니코틴 의존도가 유의한 차이를 보였다. 니코틴 의존도는 금연 자기효능감(r=-.54, p<.001), 사회적지지(r=-.26, p=.001)와 음의 상관관계를, 우울(r=.33, p<.001)과는 양의 상관관계를 나타냈다. 니코틴 의존도에 영향을 미치는 변수는 금연 자기효능감(${\beta}=-.48$, p<.001), 우울(${\beta}=.17$ p=.027)로 나타났고, 이들 변수의 니코틴 의존도에 대한 설명력은 34%이었다. 결론적으로, 남자 흡연 대학생을 위한 금연중재프로그램 적용 시 금연 자기효능감을 증진시키고, 우울을 감소시키는 방안이 필요하다.

Establishment of a linear regression equation for quantification of beta-hemolytic Escherichia coli in different media and survival of hemolytic Escherichia coli after blending with three different media

  • Kim, Jae Cheol;Pluske, John R.;Yoo, Jaehong;Heo, Jung Min
    • 농업과학연구
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    • 제41권2호
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    • pp.135-139
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    • 2014
  • Pathogenic E. coli associated post-weaning diarrhea (PWD) and edema disease are common diseases in commercially-housed weanling pigs. An enterotoxigenic E. coli (ETEC) oral challenge model has been used to mimic the physiological responses observed in commercial conditions. However, an oral challenge procedure has two major limitations: (1) the ETEC cell density is unknown at the point of oral inoculation, and (2) blending ETEC with traditional TSB (trypticase soy broth) is not palatable and hence decreases acceptability by piglets. Therefore, the purposes of this study were to (1) establish a regression equation that can be used for estimation of ETEC concentration in dilution media using the spectrophotometric measurement of cell density; and (2) examine survival of ETEC after blending either with TSB, sweetener or dextrose. A strain of ETEC (serogroup beta-hemolytic E. coli O149; K91; F4; toxins LT, STa, STb) was grown in TSB for 3.5 hours, centrifuged, the supernatant was discarded, and the ETEC pellet was then blended either with TSB (100 mL), sweetener (60 mL TSB + 40 mL fruit flavored concentrate), or dextrose (50 mL TSB + 50 mL dextrose; 0.5g/mL dextrose). Cell density was measured using the colorimetric method and also plated on a 5% sheep blood agar for counting of ETEC colony forming units at 0, 5, 35, 65 and 125 min after blending. The optical density at 600 nm explained 83% of ETEC colony forming units, indicating that the established linear equation (y= 6E+08x - 4E+07, P<0.004) can be used for robust quantification of ETEC cell density in TSB, sweetener and dextrose media. When ETEC was blended with sweetener and dextrose, survival of ETEC was decreased by 45% and 72% within 5 min post-blending. Therefore, further research is required to find out the suitable medium that has potential to improve palatability without compromising survival of ETEC.

간호대학생의 부모자녀 친밀감, 부모자녀 의사소통, 공감능력이 임상수행능력에 미치는 영향 (The Effects of Parent-Adolescent Intimacy, Parent-Adolescent Communication, and Empathy on Clinical Competency of Nursing Students)

  • 김종근;천의영;유장학
    • 대한통합의학회지
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    • 제6권1호
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    • pp.15-24
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    • 2018
  • Purpose : This study aimed to identify the effects parent-adolescent intimacy, parent-adolescent communication, and empathy on the clinical competency of nursing students. Method : Data were collected by 175 nursing students using a self-questionnaire from May 17 to 31, 2017. The data were analyzed with the SPSS 21.0 using an independent t-test, Pearson correlation coefficients, and multiple regression. Result : There were significant positive correlations between clinical competency and the other variables. The strongest predictors of clinical competency were parent-adolescent intimacy (${\beta}=.33$) and academic record (${\beta}=.21$), and the model explained 11.3% (F=16.04, p<.001) of the variance. Conclusion : The findings indicated that further studies are needed to explore various factors influencing clinical competency and develop education programs for college nursing students.

물리치료사의 직무 및 조직특성이 전문직업성에 미치는 영향에 관한 연구 (A Study on the Relation Between Physical Therapist Professionalism and Organizational and Job Characteristics)

  • 고관우;이경원;서삼기
    • The Journal of Korean Physical Therapy
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    • 제25권5호
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    • pp.343-351
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    • 2013
  • Purpose: This study was designed to measure the level of professional autonomy regarding physical therapists and to determine the association of organizational and occupational characteristics of the profession with its professional autonomy. Methods: We utilized a structured questionnaire survey of physical therapists (280 persons) in Jeju province. Data were collected from June 25 to July 14 in 2012. An additional 173 (63%) of them were used in the final analysis. Using PASW 18.0, descriptive and Hierarchical Linear Model were performed. Results: Regression analysis Result of Factors influencing Physiotherapist Professionalism, refresher training course (t=4.27), formalization (t=3.13), task significance (t=3.39), and autonomy (t=4.17) had a positive effect. Autonomy (${\beta}$=0.33) and formalization (${\beta}$=0.33) exerted the greatest influence. Conclusion: The survey regarding organizational and job characteristics showeds that occupational reeducation, formalization, and self- regulation constitute a positive part of what the professional autonomy is to be upheld. Results of the survey imply that in order to establish professional autonomy for the profession of physical therapist, the organization must make various efforts to beef up the exclusive knowledge and technology, and professional norms of the occupation that are considered essential for specific problem solving.

일 지역 여고생의 유방자가검진에 대한 지식 및 태도가 유방자가검진 실천의지에 미치는 영향 (Influences on Practical Intention of Breast Self-Examination among High School Girls' Knowledge and Attitude about Breast Self-Examination)

  • 정복례;이선희;성정혜;전영미
    • 보건교육건강증진학회지
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    • 제31권2호
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    • pp.79-87
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    • 2014
  • Objectives: The purpose of this study was to determine the Influences on practical intention of Breast Self-Examination (BSE) in high school girls' knowledge and attitude about BSE. Methods: The participants were 208 high school girls from D city. Data were collected from August 7, to August 9 in 2013 by a questionnaire. Data were analyzed with SPSS/WIN 19.0 using ANOVA, one sample t-test, Pearson correlation, and stepwise multiple regression. Results: The factors influencing the practical intention of BSE were attitude (${\beta}=.370$) and knowledge (${\beta}=.138$). The explanatory power of this model was 16.7%. Conclusions: The results of this study revealed that knowledge and positive attitude of BSE influenced on the practical intention of BSE. Therefore, It is needed to develop the education program to obtain the knowledge and positive attitude of BSE for high school girls.

사이버대학교 공학계열 학생들의 숙달접근목표지향성, 과제가치, 자기조절학습전략의 학업만족도와 학업성취도 예측력 규명 (The Prediction of Mastery-Approach Goal Orientation, Task Value, and Self-Regulated Learning Strategy on Academic Satisfaction and Achievement of Cyber Engineering University Students)

  • 주영주;정애경;설현남;이상회
    • 전자공학회논문지 IE
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    • 제49권2호
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    • pp.65-74
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    • 2012
  • 본 연구는 사이버대학교 공학계열 학생들의 숙달접근목표지향성, 과제가치, 자기조절학습전략의 학업만족도와 학업성취도에 대한 예측력을 규명하는 데 있다. 이를 위해 H 사이버대학교의 2011년 1학기 정보통신학과의 세 과목을 등록한 219명을 대상으로 웹서베이를 실시하였으며, 수집된 데이터를 바탕으로 숙달접근목표지향성, 과제가치, 자기조절학습전략을 예측변인으로, 학업만족도와 학업성취도를 결과변인으로 설정하여 중다회귀분석을 실시하였다. 연구 결과, 과제가치(${\beta}$=.401)와 자기조절학습전략(${\beta}$=.401)은 학업만족도를 유의하게 예측하였으며, 자기조절학습전략(${\beta}$=.301)과 숙달접근목표지향성(${\beta}$=.196)은 학업성취도를 유의하게 예측하였다. 이와 같은 연구결과를 토대로 사이버대학교 공학계열 학생들의 학업만족도와 성취도를 향상시키기 위해 숙달접근목표지향성, 과제가치, 자기조절학습전략을 높이는 구체적인 증진방안이 고려되어야 할 것이다.

범이론적모델을 이용한 교대근무 간호사의 운동행위 변화단계에 미치는 융합적인 영향요인 (Converged Influencing Factors on the Stages of Exercise Behavior Change of Nurses in Shift Work Using Transtheoretical Model)

  • 이혜경;정영진
    • 융합정보논문지
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    • 제7권6호
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    • pp.35-43
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    • 2017
  • 본 연구의 목적은 교대근무 간호사의 운동행위변화단계에 미치는 융합적 영향요인을 분석하는데 있다. 연구대상자는 병원에 근무하는 교대근무 간호사로 연구의 목적을 이해하고 연구에 참여할 것을 동의한 120명의 간호사이다. 연구 자료는 빈도, 백분율, 평균, 표준편차, t-test, $X^2$ test, 다중 로지스틱 회귀분석을 이용하여 분석하였다. 교대근무 간호사의 운동행위변화단계에 유의한 영향을 미치는 요인은 운동 동기(${\beta}=2.480$, p=.022), 건강상태 지각(${\beta}=1.151$, p=.013), 사회적지지(${\beta}=1.819$, p=.002)와 결혼유무(${\beta}=-1.820$, p=.004)로 나타났다. 즉, 운동행위 변화가 있는 대상자가 운동행위 변화가 없는 대상자에 비해 운동 동기가 11.9배 높고, 건강상태 지각은 3.1배 높았으며 사회적 지지는 6.1배, 미혼인 대상자는 기혼인 대상자에 비해 .16배 높았다. 그러므로 교대근무간호사의 운동행위 변화단계에 영향을 미치는 요인이 운동동기와 사회적지지, 건강상태 지각인 점을 고려하여 지속적이고 규칙적인 운동을 실천하기 위한 전략을 개발하는 것이 중요하다.