• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.24 no.9
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• pp.679-684
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• 2012

This paper aims to evaluate performances of ventilation and insulation of 6types PVS(Passive ventilation skin) by numerical simulation. The results are as follows. 1) The result of Performance of ventilation by pressure difference, it was shown that the amount of ventilation changed bigger under 1Pa and amount of ventilation increased according to increase opening area (${\alpha}A$). Although same opening area of PVS, it can predict that pressure differences cause ventilation differences. 2) In case of same opening area of PVS, however, it was changed the amount of ventilation each types of PVS that is distinguished opening area by flow coefficient. 3) Dynamic U-value that represents performance of insulation PVS was similar change upper ${\alpha}A40\;cm^2/m^2$, great change in casse of 0.1 Pa pressure difference. In case of ${\alpha}A10\;cm^2/m^2$, it was changed bigger under 0.3 Pa pressure difference, ${\alpha}A20\;cm^2/m^2$ of PVS was changed under 0.2 Pa pressure difference.

• Tuberculosis and Respiratory Diseases
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• v.43 no.4
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• pp.637-644
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• 1996

Interstitial pneumonitis associated with interferon alpha therapy for chronic hepatitis C was first describe6 in 1994 by Kazoo et al In Japan. The mechanism of interstitial pneumonitis developed by interferon alpha was still unknown but immunologic, allergic of direct lung toxicity were suggested. We experienced a case of interstitial pneumonitis developed during interferon alpha therapy for chronic hepatitis C in a 52-year-old male patient. He was treated with 6 million units of interferon alpha intramuscularly 3 times per week for 4 weeks and noted progressive dyspnea and cough. These symptoms were subsided after 6 weeks' discontinuation of interferon alpha therapy. And so, he was retreated with 3 million units of interferon alpha 3 times per week for 8 weeks and felt dyspnea again. He was admitted to our hospital for further evaluation of progressive dyspnea. Arterial blood gas(ABG) values were $PaO_2$ 90.7 mmHg and $PaCO_2$ 31.9 mmHg, and antinuclear antibody(ANA) was negative. A chest X-ray film revealed diffuse reticulo-nodular shadows in bilateral lung fields, suggesting a diagnosis of interstitial pneumonitis. A marked increase in lymphocyte count and suppressor T cell were observed in bronchoalveolar lavage(BAL) fluid. Lymphocyte stimulation test with interferon alpha was positive. Interstitial pneumonitis was confirmed by transbronchial lung biopsy. After discontinuation of interferon alpha, we gave oral steroid in the condition that clinical symptoms were being improved gradually.

• Clinical and Experimental Pediatrics
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• v.62 no.3
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• pp.108-112
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• 2019

Subacute sclerosing panencephalitis (SSPE) is a rare, progressive, and fatal central nervous system disorder resulting from persistent measles virus infection. Long-term data are scarce, with a maximum follow-up period of 10 years. Interferon-alpha ($IFN-{\alpha}$) is a protein that exerts its antiviral activity via enhancement of cellular immune response and is reported to be an effective drug for the treatment of SSPE. However, there is currently no consensus regarding the optimal duration of $IFN-{\alpha}$ therapy. Here, we present a case report of a patient with SSPE treated with long-term intraventricular $IFN-{\alpha}$ therapy, which facilitated clinical improvement and neurological stabilization without causing serious adverse effects. To the best of our knowledge, this is one of the longest follow-up studies investigating a patient with SSPE receiving intraventricular $IFN-{\alpha}$ treatment. Further studies are necessary to validate the benefits and safety of long-term intraventricular $IFN-{\alpha}$ treatment in patients with SSPE.

• Journal of the Korean Mathematical Society
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• v.44 no.6
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• pp.1267-1279
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• 2007

For a ring endomorphism ${\alpha}$ and an ${\alpha}-derivation\;{\delta}$ of a ring R, we study relation between the set of annihilators in R and the set of annihilators in nearring $R[x;{\alpha},{\delta}]\;and\;R_0[[x;{\alpha}]]$. Also we extend results of Armendariz on the Baer and p.p. conditions in a polynomial ring to certain analogous annihilator conditions in a nearring of skew polynomials. These results are somewhat surprising since, in contrast to the skew polynomial ring and skew power series case, the nearring of skew polynomials and skew power series have substitution for its "multiplication" operation.

• Biomolecules & Therapeutics
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• v.22 no.2
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• pp.93-99
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• 2014

The interaction between viral HA (hemagglutinin) and oligosaccharide of the host plays an important role in the infection and transmission of avian and human flu viruses. Until now, this interaction has been classified by sialyl(${\alpha}2-3$) or sialyl(${\alpha}2-6$) linkage specificity of oligosaccharide moieties for avian or human virus, respectively. In the case of H5N1 and newly mutated flu viruses, classification based on the linkage type does not correlate with human infection and human-to-human transmission of these viruses. It is newly suggested that flu infection and transmission to humans require high affinity binding to the extended conformation with long length sialyl(${\alpha}2-6$)galactose containing oligosaccharides. On the other hand, the avian flu virus requires folded conformation with sialyl(${\alpha}2-3$) or short length sialyl(${\alpha}2-6$) containing trisaccharides. This suggests a potential future direction for the development of new species-specific antiviral drugs to prevent and treat pandemic flu.

• Bulletin of the Korean Mathematical Society
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• v.51 no.4
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• pp.957-964
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• 2014

In this paper, we prove that there is no branch point in the Lorentz space (M, d) which is the limit space of a sequence {($M_{\alpha},d_{\alpha}$)} of compact globally hyperbolic interpolating spacetimes with $C^{\pm}_{\alpha}$-properties and curvature bounded below. Using this, we also obtain that every maximal timelike geodesic in the limit space (M, d) can be expressed as the limit curve of a sequence of maximal timelike geodesics in {($M_{\alpha},d_{\alpha}$)}. Finally, we show that the limit space (M, d) satisfies a timelike triangle comparison property which is analogous to the case of Alexandrov curvature bounds in length spaces.

• Honam Mathematical Journal
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• v.25 no.1
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• pp.83-91
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• 2003

We prove a unique continuation theorem for $C^{\infty}$ functions in pseudoconvex domains in ${\mathbb{C}}^{n}$. More specifically, we show that if ${\Omega}$ is a pseudoconvex domain in ${\mathbb{C}}^n$, if f is in $C^{\infty}({\Omega})$ such that for all multi-indexes ${\alpha},{\beta}$ with ${\mid}{\beta}{\mid}{\geq}1$ and for any positive integer k, there exists a positive constant $C_{{\alpha},{\beta},{\kappa}}$ such that $$|{\frac{{\partial}^{{\mid}{\alpha}{\mid}+{\mid}{\beta}{\mid}}f}{{\partial}z^{\alpha}{\partial}{\bar{z}}^{\beta}}{\mid}{\leq}C_{{\alpha},{\beta},{\kappa}}{\mid}f{\mid}^{\kapp}}\;in\;{\Omega}$$, and if there exists $z_0{\in}{\Omega}$ such that f vanishes to infinite order at $z_0$, then f is identically zero. We also have a sharp result for the case of strongly pseudoconvex domains.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.17 no.4
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• pp.267-278
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• 2013

We consider zero range processes with density dependent jump rates g given by $g=g(n,k)=g_1(n)g_2(k/n)$ with $g_1(x)=x^{-\alpha}$ and $$g_2(x)=\{^{x^{-\alpha}\;if\;a&lt;x}_{Mx^{-\alpha}\;if\;x{\leq}a}$$. (0.1) In this case, with 1/2 < a < 1 and ${\alpha}$ > 0, we show that non-complete condensation occurs with maximum cluster size an. More precisely, for any ${\epsilon}$ > 0, there exists $M^*$ > 0 such that, for any 0 < M ${\leq}M^*$, the maximum cluster size is between (a - ${\epsilon}$)n and (a + ${\epsilon}$)n for large n. This provides a simple example of non-complete condensation under perturbation of rates which are deep in the range of perfect condensation (e.g. ${\alpha}$ >> 1) and supports the instability of the condensation transition.

• Journal of the Korean Statistical Society
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• v.26 no.4
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• pp.543-554
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• 1997

A family of some capability indices { $C_{p}$(.alpha.,.beta.); .alpha..geq.0, .beta..geq.0}, containing the indices $C_{p}$, $C_{{pk}}$, $C_{{pm}}$, and $C_{{pmk}}$, has been defined by Vannman(1993) for the case of two-sided specification interval. By varying the parameters of the family various capability indices with suitable properties are obtained. We derive tha asymptotic distribution of the family { $C_{p}$(.alpha.,.beta.); .alpha..geq.0,.beta..geq.0} under general proper conditions. It is also shown that the bootstrap approximation to the distribution of the estimator $C_{p}$(.alpha., .beta.) is vaild for almost all sample sequences. These asymptotic distributions would be used in constructing some bootstrap confidence intervals.tervals.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5895-5900
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• 2014

Background: Metabolic syndrome (MS) is a cluster of complicated disorders caused by the interactive influencing factors of heredity and environment, which predisposes to many cnacers. Results from epidemic research indicate that stress is tightly related to the pathogenesis of MS and neoplasia. This paper aims to investigate the association between psychological stress and MS with respect to the tumor necrosis factor alpha (TNF${\alpha}$) and neuropeptide Y (NPY) genes in the Han and Hui ethnic groups. Methods: All subjects for this case-control study matched strict enrollment criteria (nationality, gender and age) and lived in the city of Wu Zhong of Ningxia Province in China. The enrolled group contained 102 matched pairs of Hui ethnic individuals and 98 matched pairs of Han ethnic individuals. Enrolled subjects completed the general Symptom Checklist-90 (SCL-90). The TNF${\alpha}$-308G/A variant and NPYrs16147 polymorphism were detected in case (81 males, 119 females) and control (81 males, 119 females) groups by polymerase chain reaction (PCR) amplification. Results: Nine factors of the SCL-90 were found to be statistically different (p<0.05) between case and control groups. The homozygous mutant genotype (AA) and the mutant allele (A) of the TNF${\alpha}$-308G/A gene were less frequently observed in the control population compared to the case group. The odds ratio (95% confidence interval) in "Allele" for MS was 2.28 (1.47-3.53), p=0.0001, while "OR" was 1.11 (0.83-1.47), p=0.15, for the NPYrs16147 gene polymorphism. Conclusions: Psychological stress has been positively associated with MS. A previous study from our group suggested there were differences in the level of psychological stress between Hui and Han ethnic groups. Furthermore, we found that the stress-related TNF${\alpha}$ gene was associated with MS for both Han and Hui ethnic groups. In contrast, NPY may be a possible contributor to MS and associated cancer for the Han ethnic group.