• Title/Summary/Keyword: aging factor

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A modified Lee-Carter model based on the projection of the skewness of the mortality (왜도 예측을 이용한 Lee-Carter모형의 사망률 예측)

  • Lee, Hangsuck;Baek, Changryong;Kim, Jihyeon
    • The Korean Journal of Applied Statistics
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    • v.29 no.1
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    • pp.41-59
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    • 2016
  • There have been continuous improvements in human life expectancy. Life expectancy is as a key factor in an aging population and can wreak severe damage on the financial integrity of pension providers. Hence, the projection of the accurate future mortality is a critical point to prevent possible losses to pension providers. However, improvements in future mortality would be overestimated by a typical mortality projection method using the Lee-Carter model since it underestimates the mortality index ${\kappa}_t$. This paper suggests a mortality projection based on the projection of the skewness of the mortality versus the typical mortality projection of the Lee-Carter model based on the projection of the mortality index, ${\kappa}_t$. The paper shows how to indirectly estimate future t trend with the skewness of the mortality and compares the results under each estimation method of the mortality index, ${\kappa}_t$. The analysis of the results shows that mortality projection based on the skewness presents less improved mortality at an elderly ages than the original projection.

Relationship among Photosynthesis, Grain Filling and Temperature of Rice Cultivars by Shifted of Heading Date (벼 품종들의 출수기 이동에 따른 광합성 및 온도와 등숙과의 관계)

  • 이석영
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.40 no.3
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    • pp.398-405
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    • 1995
  • In termperate zone planting rice at different date subjects the crop to different climatic condition. This study aimed at comparison of the change in source-sink relationship of the Japonica(J) and that of Indica Japonica(I$\times$J) type rice cultivars caused by shift of heading date. Two J-and two I$\times$J-type cultivars were made to head on Aug. 16, Aug. 26 and Sep. 5. Percent grain fertility was not changed in response to shift of heading date. Ripening patterns of 4 rice cultivars were similar to sigmoid curve type but when the heading date was delayed to Sep. 5, the form is changed to log type of curve. In J-type, physiological maturity was delayed about 5 day when headed at Sep. 5, in compare to headed at Aug. 16 and Aug. 26. However ripening was continued about 10 days when the diurnal, nocturnal and minimum temperature was above 17, 12$^{\circ}C$ and about 3~8$^{\circ}C$. In I$\times$J hybrid, real ripening was continued when the diurnal, nocturnal and minimum temperature was over 20, 17$^{\circ}C$, but if the minimum temperature was downed bellow 1$0^{\circ}C$, it was impossible. Simulated photosynthetic amount based on photosynthetic ability, temperature, leaf area and day length was varied according to changes in heading date and it was decreased seriously if the minimum temperature was fall down bellow 4$^{\circ}C$ in field, that's why decrease in photosynthetic ability and aging. The temperature range of optimum ripening was 21~26$^{\circ}C$, if there is nothing hindering factor.

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A Study on Optimization of Spray Type Flue Gas Desulfurization (FGD) System (모사 탈황흡수탑을 이용한 Spray Type 탈황설비 최적운전 방안에 관한 연구)

  • An, Hi-Soo;Park, Seung-Soo;Kim, Ki-Hyoung;Kim, Young-Ho
    • Applied Chemistry for Engineering
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    • v.18 no.1
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    • pp.29-35
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    • 2007
  • Recently, due to narrow margin on design factor of flue gas desulfurization (FGD) systems or aging of systems, some problems such as decrease of $SO_2$ removal efficiency and difficulty on coping with unstable state are arising on FGD systems. On this study, to cope with these problems several methods such as adjustment of reagent pH, inlet $SO_2$ concentration, variation of units of operation pump, installation of liquid distribution ring (LDR) were attempted to increase the $SO_2$ removal using spray type simulated FGD system. Also, sulfite and Al/Fx ion effects on limestone blinding were experimented. When three absorber recirculation pumps were operated, $SO_2$ removal was increased by 12% in comparison with that of two pumps operation. $SO_2$ removal was increased by 2~7% after installation of LDR. Dissolved oxygen increased up to 0.5 ppm and limestone binding effect was alleviated after injection of dibasic acid (DBA) with the concentration of 500 and 1,000 ppm. When $Al^{3+}$ and $F^-$ ions were coexisting, the dissolution rate of limestone was decreased by 20%.

The Antiapoptic Effects of Hominis Placenta Extract

  • Seo, Jung-Chul;Chung, Joo-Ho;Ahn, Byoung-Choul
    • Journal of Pharmacopuncture
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    • v.4 no.1
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    • pp.123-124
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    • 2001
  • Purpose. Free radicals are implicated in the pathophysiology of aging, ischemic injury and neurodegenerative disorders. To deform]no whether Hominis Placenta extract prevents $H_2O_2$-induced apoptosis, we have performed morphological and biochemical analyses for the detection of apoptotic phenomena in the pineal tumor cell line $PGT-{\beta}$ We have also peformed cytochemical and immunocytochemical analyses for the detection of changes in nitric oxide synthase (NOS) activity and estimated the expression . of apoptotic genes using reverse transcription-polymerase chain reaction (RT-PCR) Methods. $PGT-{\beta}\;cells$ were pretreated with Hominis Placenta extracts $(0,\;10^{-2}\;{\mu}g/ml)$ for 2 hours and then exposed to $H_2O_2\;(0,\;50\;{\mu}M)$ for 3 hours. Appearance of apoptotic characteristics were monitored using 4, 6-diamidino-2-phenylindole dihydrochloride (DAPI) staining assay, terminal deoxynucleotidyl transferase-mediated dUTP-digoxigenin nick end labeling (TUNEL) assay and flow cytometric analysis. NOS activity was measured by NADPH-diaphorase cytochemistry. Expression of inducible NOS (iNOS) and nuclear factor kappa B (NF k B) was assessed via immunocytochemistry. The expression of apoptotic genes was examined by RT-PCR. Results. After 3 flours of exposure to $H_2O_2$, it was shown that $PGT-{\beta}\;cells$ treated with $H_2O_2(50\;{\mu}M)$ exhibit classical apoptotic features and increases in NOS activity and caspase-3 expression. Treatment with Hominis Placenta extract resulted in a reduced occurrence of apoptotic features. DAPI staining, TUNEL and flow cytometric assays revealed decreases in the occurrence of nuclear fragmentation and in the sub-Gl fraction in the $PGT-{\beta}\;cells$ treated with Hominis Placenta extract. Cells treated with Hominis Placenta extract also showed lower activity of NADPH-diaphorase and immunoreactivities of both iNOS and NF k B than those of $H_2O_2$-treated cells which were not treated with Hominis Placenta extract. By RT-PCR, it was shown that the level of caspase-3 mRNA was derreased In the cells treated with Hominis Placenta . extract. Conclusions. This study shows that Hominis Placenta extract prevents $H_2O_2$-induced apoptosis in $PGT-{\beta}\;cells$; inhibitions of iNOS and caspnse-3 are possible mechanisms of the protection against apoptosis.

Impact of Depression and Family Relationship on Problem Drinking among Older Adults (노인의 우울과 가족관계가 문제음주에 미치는 영향연구)

  • Yoon, Suk-Ja
    • Journal of Digital Convergence
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    • v.14 no.4
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    • pp.11-17
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    • 2016
  • This study is to examine the effect that the degree of alcohol use and the factor of family relationship have on alcohol related problem with elderly people over 65 years old. The study utilized the data from Korea Welfare Panel Study in 2014 published in 2015, which is annually conducted nationwide study. AUDIT (Alcohol Use Disorder Identification Test) of the World Health Organization scale to assess the drinking problem in the study was used. The collected data were analyzed using SPSS 21.0. Presenting some discussions on the basis of the results of this study is as follows. First, looking at a cross-analysis of gender differences in drinking problems, elderly men and elderly women showed different degrees of alcohol problems. Second, looking at demographic characteristics that influence whether a drinking problem, younger age showed a serious drinking problem. Third, looking at the effect that depression and family relationship have on alcohol problem, depression appeared to have relatively more serious effect than the family relationship. According to the above finding, physical and mental health for healthy aging are important factors of the quality of life so a preventive approach to maintain healthy habits is considered to be essential.

Oxidation characteristics of solder alloys for the photovoltaic module (태양전지 묘듈용 솔드 합금의 산화 특성)

  • Kim, Hyo Jae;Lee, Young Eun;Lee, Gu;Kang, Gi Hwan;Choi, Byung Ho
    • Journal of the Korean Solar Energy Society
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    • v.34 no.1
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    • pp.98-104
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    • 2014
  • Photovoltaic (PV) cell is considered as one of the finest ways to utilize the solar power. A study of improving solar cell's efficiency is important because the lifetime of solar cell is determined by photovoltaic module technology. Therefore, oxidation (and/or corrosion) of solder materials will be one of the primary yield and long-term reliability risk factor. Recently, the development of lead-free solder alloy has been done actively about lead-free solder alloys of the thermodynamic and mechanical properties. However, the oxidation behavior have rarely been investigated In this study, the oxidations of 60 wt% Sn-40 wt% Pb, 62 wt% Sn-36 wt% Pb -2 wt% Ag, 50wt% Sn-48 wt% Bi-2 wt% Ag alloys for the interconnect ribbon after exposure in atmosphere at $100^{\circ}C$ for several times were investigated. The wettability of 62 wt% Sn-36 wt% Pb-2 wt% Ag and 50 wt% Sn-48 wt% Bi-2 wt% Ag solders was also studied to compare with that of 60 wt% Sn-40 wt% Pb alloy. The results howed that the zero cross time and the wetting time of 50 wt% Sn-48 wt% Bi-2 wt% Ag solder were better than other two samples. The surface of tested samples was analyzed by XPS. The XPS result showed that in all samples, SnO grew first and then the mixture of SnO and $SnO_2$ was detected. $SnO_2$ grew predominantly for the long time aging. Moreover XPS depth profile analysis has found surface enrichment of tin oxide.

Promotive Effect of Polygonum multiflorum radix Ethanol Extract on Melanogenesis (적하수오 에탄올 추출물의 melanin 합성 촉진효과)

  • Kim, Hyejeong;Kim, Moon-Moo
    • Journal of Life Science
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    • v.27 no.4
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    • pp.423-429
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    • 2017
  • Hair color is determined by kind and amount of melanin. Melanocyte mainly synthesizes melanin from L-tyrosine by stimulation of ultra violet. Reactive oxygen species (ROS) play an important role in greying hair. Polygonum multiflorum radix has been reported to inhibit the aging process that black color of hair is turned into grey color. The aim of this study is to investigate the effect of Polygoni multiflorium radix ethanol extract (PMEE) on melanin synthesis related to black hair growth. In anti-oxidant experiment, PMEE decreased DPPH radical and increased reducing power, indicating that PMEE could eliminate ROS involved in greying hair. PMEE decreased cell viability in a dose-dependent manner. Furthermore, the effect of PMEE on the production of melanin was determined by DOPA assay and tyrosinase activity. PMEE increased tyrosinase activity and promoted melanin synthesis. In addition, the expression levels of tyrosinase, tyrosinase related protein-1 (TRP-1), tyrosinase related protein-2 (TRP-2) and microphthalmia-associated transcription factor (MITF), as well as anti-oxidant enzymes such as superoxide dismutase (SOD-3) and catalase were examined using western blot analysis. The expression levels of SOD-3 and catalase were decreased due to the enhanced antioxidant activity of PMEE. In particular, PMEE increased the expression levels of tyrosinase and TRP-2. These results suggest that PMEE could promote melanin synthesis that involved in tuning gray hair into black hair.

The Effect of Cream containing Acetyl hexapeptide upon the Facial Skin (Acetyl hexapeptide 함유 크림이 안면 피부 변화에 미치는 영향)

  • Choi, Jeong-Yun;Oh, Sung-Cheon
    • Journal of the Korean Applied Science and Technology
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    • v.31 no.1
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    • pp.120-129
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    • 2014
  • The structure and physiological function of human skin continuously weaken due to growing older. The reasons of aging from external conditions are long term exposure to sun, wind, heat, cigarette smoke, and etc. This also palmitoyl oligopeptide or ceramide oligopeptide are known asc ingredient stimulating collagens and have the effect of reproducing the upper level of skin. Acetyl hexapeptide is an ingredient that makes the skin and muscle suppler and reduces wrinkles. It is a major high function beauty ingredient that substitutes botox. After dividing 7%, 14%, and 20% Acetyl hexapeptide experimental groups as groups A, B, and C the control group and experiment groups' change of wrinkles, hair follicles, moisture content, and dead skin cells was analyzed. According to the results, Acetyl hexapeptide seems to affect wrinkles, hair follicles and moisture content contrasting to the control group. Experimental groups and control group showed similar change in dead skin cells. In contrast to the control group satisfaction of examines was affected in wrinkles, hair follicles and moisture but removing dead skin cells had similar result in experimental groups and control group.

Evaluation of marginal leakage of bulk fill flowable composite resin filling with different curing time using micro-computed tomography technology (Bulk fill 유동성 복합레진의 변연 누출에서 다른 중합시간의 영향에 대해 마이크로시티를 이용한 평가)

  • Kim, Eun-Ji;Lee, Kyu-Bok;Jin, Myoung-Uk
    • Journal of Dental Rehabilitation and Applied Science
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    • v.32 no.3
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    • pp.184-193
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    • 2016
  • Purpose: To evaluate marginal leakage of bulk fill flowable composite resin filling with different curing time by using microcomputed tomography technology. Materials and Methods: 30 previously extracted human molars were randomly divided into 6 groups based upon restorative system and different curing time. Class II cavities (vertical slot cavities) were prepared. An individual metallic matrix was used to build up the proximal wall. The SonicFill or SureFil SDR flow was inserted into the preparation by using 1 bulk increment, followed by light polymerization for different curing times. The different exposure times were 20, 40, and 60 seconds. All specimens were submitted to 5,000 thermal cycles for artificial aging. Micro-CT scanning was performed by using SkyScan 1272. One evaluator assessed microleakage of silver nitrated solution at the resin-dentin interface. The 3D image of each leakage around the restoration was reconstructed with CT-Analyser V.1.14.4. The leakage was analyzed with the Mann-Whitney test. Results: Significant differences were observed between the light curing times, but no significant differences were found between the bulk fill composite resins. Increasing in the photoactivation time resulted in greater microleakage in all the experimental groups. Those subjected to 60 seconds of light curing showed higher microleakage means than those exposed for 20 seconds and 40 seconds. Conclusion: Increasing the photoactivation time is factor that may increase marginal microlekage of the bulk fill composite resins. Further, micro-CT can nondestructively detect leakage around the resin composite restoration in three dimensions.

A Proposal for Development of the Certification and Level System of Construction Craft Workers (건설기능인력 자격 및 직급체계 구축방안 제안)

  • Kim, Bong-Ju;Jung, Myung-Ho;Hyun, Chang-Taek;Koo, Kyo-Jin;Moon, Hyun-Seok
    • Korean Journal of Construction Engineering and Management
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    • v.7 no.5
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    • pp.105-114
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    • 2006
  • The construction craft workers have been getting older and have become drained, in spite of the vital factor that it directly affects productivity and quality as a final producer. This situation in the construction industry is ultimately due to evasion of performances by young craft workers. Therefore, the aim of this study is to propose the certification and level system of construction craft workers and to extract young craft workers from the market for construction craft workers so as to supply and demand high quality of craft workers. First of all, the present status and problems of the domestic construction craft workers are considered in this study. Furthermore, the appropriate way to establish its certification and level system is suggested from the Interview with experts, as well as references of German and Australian case. The revitalization of certification and level system provided in this study is expected to ensure that the craft workers are not simple laborers, but are required the professional knowledge and skill. Besides, it will lead to strengthen specificity and to break from aging, by taking young and qualified craft workers into the construction industry. Also, it will promote an employment stability by connecting the social security system.