• Advances in Traditional Medicine
• /
• 제8권2호
• /
• pp.103-110
• /
• 2008

Herbal medicine is the use of medicinal plants for prevention and treatment of diseases: it ranges from traditional and popular medicines of every country to the use of standardized and tritated herbal extracts. Generally cultural rootedness enduring and widespread use in a traditional medical system may indicate safety, but also efficacy of treatments, especially in herbal medicine where tradition is almost completely based on remedies containing active principles at very low and ultra low concentrations or relying on magical-energetic principles. The efficacy and safety assessments of medicines, whether modern or herbal, invariably encounter challenges or problems during the course of pre-clinical and clinical research. Some of the challenges in evidence-based herbal medicinal research are unique, and the researcher must be cognizant of them in order to safeguard the quality of the data obtained. Key challenges are: the quality of raw materials; appropriateness of biological/pharmacological activity assessment methodology, and data interpretation; standardization methodology; pharmacokinetics and bioavailability of active constituents and metabolites; clinical dosage formulation/production; and clinical study designs and outcome measures.

• 한국자동차공학회논문집
• /
• 제21권5호
• /
• pp.162-168
• /
• 2013

Recently, there have been efforts in many countries to reduce social expenses and casualties resulting due to car accidents. As such, ASS (active safety systems) are being researched and developed to prevent accidents and target mitigation. Among many useful active safety systems, it has been reported that commercial AEBS (Advanced Emergency Braking System) effectively prevents accidents and reduces casualties simultaneously. Accordingly, it is necessary to set Korean AEBS standards, and this research analyzes international AEBS standards for this necessity. In addition to the evaluation methodology of AEBS ECE Regulation, this study suggests traffic scenarios that occur frequently in domestic road environments, and provides an evaluation system for AEBS of the scenarios. Finally, the performance and safety of AEBS are evaluated through field test.

• Nuclear Engineering and Technology
• /
• 제49권7호
• /
• pp.1431-1441
• /
• 2017

The Fukushima accident reveals the vulnerability of existing active nuclear power plant (NPP) design against prolonged loss of external electricity events. The passive safety system is considered an attractive alternative to cope with this kind of disaster. Also, the passive safety system enhances both the safety and the economics of NPPs. The adoption of a passive safety system reduces the number of active components and can minimize the construction cost of NPPs. In this paper, reflecting on the experience during the development of the APR+ design in Korea, we propose the concept of an innovative Power Reactor (iPower), which is a kind of passive NPP, to enhance safety in a revolutionary manner. The ultimate goal of iPower is to confirm the feasibility of practically eliminating radioactive material release to the environment in all accident conditions. The representative safety grade passive system includes a passive emergency core cooling system, a passive containment cooling system, and a passive auxiliary feedwater system. Preliminary analysis results show that these concepts are feasible with respect to preventing and/or mitigating the consequences of design base accidents and severe accidents.

• 한국정밀공학회:학술대회논문집
• /
• 한국정밀공학회 2012년도 춘계학술대회 논문집
• /
• pp.1023-1024
• /
• 2012

• 농약과학회지
• /
• 제18권4호
• /
• pp.342-349
• /
• 2014

미국, EU, 한국의 농작업자위해성평가를 위한 AOEL 설정, 국가별 경구흡수율 적용, 노출량 산출방법을 조사하였다. 농약성분 141종에 대한 경구흡수율을 조사하였으며 경구흡수율을 적용한 농작업자노출허용량(AOEL)과 국내 설정 AOEL을 이용하여 농작업자위해성평가를 실시하였다. 미국과 EU에서는 external dose를 internal dose로 변환하기 위하여 경구흡수율 또는 피부흡수율을 적용하였으나 한국에서는 AOEL 설정 시 경구흡수율을 적용하지 않은 external dose를 사용하였다. 141종의 농약성분 중 50종이 경구흡수율 80% 미만이었으며 경구흡수율을 적용하는 경우 약 36%의 농약성분이 이전 AOEL보다 낮아질 것으로 사료되었다. 50종의 농약성분 중 한국에 등록된 농약 28품목에 대해 EU AOEL을 이용하여 농작업자위해성평가를 실시한 결과, chlorothalonil WG 등 12품목이 독성노출비가 1 이하로 계산되어 위해성이 높은 것으로 나타났다. 또한 50종 중 한국 AOEL이 설정되어 있으며 한국에 등록된 농약 24품목에 대해 한국 AOEL을 이용하여 농작업자위해성평가를 실시한 결과, chlorothalonil WG 등 6품목은 독성노출비가 1 이하로 위해성이 높게 나타났다. 한국 AOEL이 없는 4품목에 대해 EU AOEL을 경구흡수율 100%로 환산한 수치를 이용하여 위해성평가를 실시한 결과, daminozide WP 등 4품목 모두 독성노출비 1 초과로 위해성이 낮게 나타났다. 경구흡수율 적용 및 미적용 EU AOEL과 한국 AOEL을 사용한 농작업자위해성평가를 비교한 결과 oxadiagyl SC 등 6품목을 제외한 22품목에서 동일한 위해성평가 결과가 나타났다. 본 연구 결과, 농작업자 위해성 평가를 실시할 때 경구흡수율을 적용한 AOEL을 이용할 수 있을 것으로 사료되었다. 경구흡수율을 적용한 AOEL 설정 및 이용한 농작업자위해성평가를 수행하였을 때 보다 실제에 가까운 평가방법으로 판단되므로 등록농약의 평가에 적용될 수 있도록 개선이 필요할 것으로 사료된다.

• 기계저널
• /
• 제45권5호
• /
• pp.53-57
• /
• 2005

• Bulletin of the Korean Chemical Society
• /
• 제23권1호
• /
• pp.75-80
• /
• 2002

Cycle life tests have been carried out to evaluate the influence of safety valve pressure on valve regulated lead/acid batteries under deep cycling applications. Batteries were cycled at 5 hour rates at 100% DOD, and safety valve pressure was set to 1.08 and 2.00 bar, respectively. The batteries lost 248.3 g and 235.3 g of water for each case after about 1,200 cycles, but the cyclic performances of the batteries were comparable. Most of the gas of the battery during discharging was hydrogen, and the oxygen concentration increased to 18% after 3 hours of charging. The micro structure of the positive active materials was completely changed and the corrosion layer of the positive grid was less than $50{\mu}m$, regardless of the pressure of the safety valve after cycle life tests. The cause of discharge capacity decrease was found to be water loss and the shedding of the positive active materials. The pressure of safety valve does not give little effect to the cyclic performances and the failure modes of the gelled electrolyte valve-regulated lead acid batteries.

• 한국자동차공학회논문집
• /
• 제16권3호
• /
• pp.23-29
• /
• 2008

It is necessary to develope the active safety system in terms of driver's safety and convenience. In this paper, we were developed the non-contact type of safety window system operated by the initial value of feedback control such as the output signal of photo sensor. It was designed based on the control algorithm with an improved load sensitivity. Therefore, compared with the existing system, it is possible to prevent the occurrence of a mull-function. Also, it has a convenient functions of the window such as an auto up/down and closing, and has a response times better. It can be installed the various types of common vehicles that have the different movement distance and speed of window. In conclusion, the developed system may be adapted the vehicle commercially.

• 대한안전경영과학회지
• /
• 제16권4호
• /
• pp.257-262
• /
• 2014

Risk information may be one of the most important factor for worker's safe behavior because that safe behavior can be oriented by attitude based on risk information. Traditionally KAP(knowledge, attitude and practice) model was useful frame for the change of human behavior. Knowledge is formed by information through experience and education. Worker's health may be prevented by his or her own active safe behavior based on risk information. This paper is to investigate the effect of labor union on the provirion of risk information by labor union. Data for analysis is the third Korean Working Conditions Survey done by Occupational Safety and Health Research Institute in 2011. The sample size is 50,032 economic active person surveyed by household interview survey with structure questionnaire by trained interviewer. The difference of risk information provision among employees was tested by mean difference test. The level of risk information of employees of companies with labor union is higher than that with non labour union. This paper has some implication for the promotion of safe behavior of employees through risk information provision mediated by labor union. Some limitation of this study may be considered because of using the cross sectional survey data.

• 자동차안전학회지
• /
• 제11권2호
• /
• pp.44-52
• /
• 2019

In this study a safety evaluation method is presented for a ADAS vehicle to be tested in collision situation when multiple vehicles are present on a single lane. Test scenarios are developed based on Euro-NCAP assessment scenarios, accident database and related simulation results in previous works. An automated evaluation system that is called as the K-target mover is used for active safety evaluation experiments. The experiments are conducted with two types of tests. First, the rear-end collision tests with 25% and 50% overlap for the test vehicle and target vehicle are conducted with the two kinds of test vehicles. On the other hand, the rear-end collision tests which include multiple vehicles in a single lane with 25% and 50% overlaps, are also conducted. Experimental results show that the test vehicles with ADAS cannot recognize the collision situation sometimes in the developed test scenarios, even in the case that the test vehicle showed stable performance in the simple overlap scenarios.