• Korean Journal of Ecology and Environment
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• v.44 no.1
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• pp.85-94
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• 2011

Present study aimed to investigate the effect of zinc accumulation on the tissues of Carassius auratus with various rearing condition. Heavy metal, Zn, was accumulated in the gill, bone and muscle increased for exposure period of 40 days. Moreover, the accumulated concentration of Zn in the gill showed relatively higher than that in other tissues. Also, activities of antioxidant enzymes in the gill, kidney, liver and muscle tissues after exposure to Zn were increased in the manner of exposure period. Antioxidant enzyme activities were shown higher in the gill and muscle than those in the kidney and liver tissues. The gill of C. auratus showed abnormal shapes in its secondary lamellae by long time exposure condition and determined the increased numbers of mucous cells in gill exposed to Zn. In addition, the edema, the exfoliation of epithelial cell was shown in the gill and membrane damages were observed in mitochondria and nucleus. In the kidney, we observed not only the atrophied glomerulus, but the expansion of empty space in Bowman's capsule. Based on the above results, it is considered that the exposure to the high level of Zn for long period possibly involves in the decrease of respiratory and excretory rates, giving rise to secondary lesion of tissues.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.4
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• pp.464-473
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• 2016

The air temperatures of the coast and inland are rising due to an increase in carbon dioxide emissions and abnormal climate phenomena caused by global warming, El Nino, La Nina and so on. The sea levels of the Earth are rising by approximately 2.0 mm per year (global average value) due to the thermal expansion of sea water, melting of glaciers and other causes by global warming. On the other hand, when it comes to designing a hydraulic structure or coastal hydraulic structure, the standard of the design water level is decided by analyzing four largeness tide values and a harmonic constant with the observed tidal water level or simulating numerical model. Therefore, the design tidal water level needs to consider an increasing speed of the seawater level, which corresponds to the design frequency. In the present study, the observed tidal water levels targeting 46 tidal stations operated by the Korea Hydrographic and Oceanographic Administration (KHOA) from the beginning of observations to 2015 per hour were collected. The variation of the monthly and yearly and increasing ratio were performed and divided into 7 seas, such as east and west part of the Southern Sea, south part and middle of the East Sea, south part and middle of the Western Sea, and Jeju Sea. The current study could be used to determine the cause of local seawater rises and reflect the design tidal water level as basic data.

• Korean Journal of Labor Studies
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• v.24 no.2
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• pp.321-365
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• 2018

Though the British shipbuilding industry dominated the world market in the 19th century, it could not avoid the repetitive rise and fall of the unemployment following after the cyclical fluctuations. Without challenging the employers' rights to fire at will, the boilermakers maintained their own unemployment insurance in order to escape from the new poverty law system. In the beginning the craft union could continue their own unemployment insurance under the National Insurance Act of 1911, but it went into bankruptcy under the massive unemployment of the 1920s and the attacks of shipyard employers. The Act of 1911 was a step towards social solidarity in that it spread the risks beyond the occupational boundaries, applying unemployment insurance to unskilled and non-union workers, and the employer and the government also paid the premium. In the Great Depression, the shipyard trade unions demanded that the government should intervene in the shipbuilding market to provide jobs, but it was not accepted by the government. The government responded only to the another demand of the union for the maintenance, which could be achieved partially through the abnormal operation of the insurance system, abandoning the insurance principle. After all, unemployment in the shipbuilding industry was resolved only by the expansion of rearmaments and the outbreak of World War II. From the 19th century to the World War II, the craft unions did not challenge the employers' right to fire at will and did not attempt to regulate dismissal procedures or make any demands on dismissal compensations. During interwar periods rules and practices related with weak employment protection - one of the main features of the liberal employment adjustment institution - were prevalent in Britain. The principle of 'employment at will' could survive through the historical events such as the World War I, II as the operation of the unemployment insurance became the focus of the social conflicts.

• Journal of the Korean GEO-environmental Society
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• v.19 no.12
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• pp.59-64
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• 2018

The damages to the reinforced earth retaining wall are divided into the front wall, foundation, drainage and upper slope. Damage of reinforced earth retaining wall is mainly caused by damage caused by drainage problem in the field. Recently, damage caused by snow removal materials have been occurred. Recently, the amount of snow removal materials used in winter is increasing due to abnormal weather. This chlorides degrades the concrete structure, where the reinforced earth retaining wall was no exception. There has recently been a case in which the front wall of the reinforced earth retaining wall deteriorates due to the chlorides introduced into the back filling portion through the drainage passage. Therefore, in this study, the cause of damages of reinforced earth retaining wall constructed in bridge abutment was analyzed, and an analytical study was conducted on the countermeasure. As a result, it was found that chlorides, which was introduced through the drainage system in the expansion joint of the bridge shift part or the upper structure, is infiltrated into the back part of the reinforced earth retaining wall and damaged. Therefore, it is suggested to improve the drainage system and restored the stiffness of the front wall.

• Journal of the Korean Regional Science Association
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• v.38 no.1
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• pp.21-32
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• 2022

The purpose of this study is two things. First, it is to develop and demonstrate a sharong taxi platform. To this end, the implications for platform development were derived by analyzing consumers' perceptions of existing taxi services using IPA. As a result, abnormal business activities and safe services in the maintenance area were found to be safe rides and easy rides in the key improvement area. Safety such as usage fee level and driver information provision were derived in the areas subject to improvement, and friendly response and internal and external cleanliness were derived in the areas of excessive investment. The second purpose of this study is to estimate the value given to users for sharing taxi service platforms using the CVM. As a result of estimating the value of the demonstration service of the shared taxi platform developed through this study, the WTP was 3,621 won/per household/per year when expanding throughout Gimhae-si, and 2,515 won/per household/per year. Compared to the willingness to pay for empirical services, only 69.5% of the willingness to pay for the spread project in Gimhae-si. This is the result of a combination of service spread to an unspecified number of people and concerns about service quality due to spatial expansion. This suggests that it is necessary to build data through continuous demonstration and to carefully build a roadmap for spread by upgrading services based on this.

• Journal of the korean academy of Pediatric Dentistry
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• v.49 no.4
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• pp.357-367
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• 2022

Sleep disordered breathing (SDB) is a disease characterized by repeated hypopnea and apnea during sleep due to complete or partial obstruction of upper airway. The prevalence of pediatric SDB is approximately 12 - 15%, and the most common age group is preschool children aged 3 - 5 years. Children show more varied presentations, from snoring and frequent arousals to enuresis and hyperactivity. The main cause of pediatric SDB is obstruction of the upper airway related to enlarged tonsils and adenoids. If SDB is left untreated, it can cause complications such as learning difficulties, cognitive impairment, behavioral problems, cardiovascular disease, metabolic syndrome, and poor growth. Pediatric dentists are in a special position to identify children at risk for SDB. Pediatric dentists recognize clinical features related to SDB, and they should screen for SDB by using the pediatric sleep questionnaire (PSQ), lateral cephalometry radiograph, and portable sleep monitoring test and refer to sleep specialists. As a therapeutic approach, maxillary arch expansion treatment, mandible advancement device, and lingual frenectomy can be performed. Pediatric dentists should recognize that prolonged mouth breathing, lower tongue posture, and ankyloglossia can cause abnormal facial skeletal growth patterns and sleep problems. Pediatric dentists should be able to prevent these problems through early intervention.

• Information Systems Review
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• v.26 no.1
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• pp.289-313
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• 2024

Korean pharmaceutical and bio-health companies began applying for FDA approval in 2000. However, drug companies in South Korea are not required to obtain FDA approval to market their products on the South Korean market, and the approval process is highly resource-intensive. This study utilizes event study methodology to examine the information effect of US FDA approval announcements on the stock prices of pharmaceutical and bio-health companies listed on South Korean stock markets. The study's results show that FDA approval announcements caused abnormal increases in corporate stock prices, indicating that these announcements have a transnational information effect on South Korean companies' value. Furthermore, the results show that the impact of FDA approval announcements on stock prices is greater for small companies than mid-sized and large companies and in bio and healthcare industries than in the traditional pharmaceutical industry. This impact is also more significant on the KOSDAQ (Korea Securities Dealers Automated Quotation) companies than the KOSPI (Korean Composite Stock Price Index) companies and after the expansion of stock price limits. These findings signal that the information effect is more significant when regulatory controls are weaker. The results also indicate that obtaining FDA approval brings above-normal returns for companies and that FDA application is a high-risk, high-return investment.

• Journal of the Korean Arthroscopy Society
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• v.13 no.1
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• pp.8-13
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• 2009

Purpose: We used tibialis allograft for the reconstruction of ACL and used Hybrid femoral fixation utilizing $Endobutton^{(R)}$ and $Rigidfix^{(R)}$ for femoral fixation, and used $Retroscrew^{(R)}$ and additional fixation for tibial fixation to evaluate the clinical results. Materials and Methods: The ACL reconstruction were performed from February 2004 to February 2007 utilizing Hybrid femoral fixation and $Retroscrew^{(R)}$ and 32 patients, 32 cases which were available for year-long observation (12 to 25 months). The clinical results (Lysholm knee score, IKDC grade) and the radiologic results(bone tunnel expansion, Telos anterior displacement test) were evaluated. Results: The Lysholm knee score was improved from the average of $67.9{\pm}5.4$ points (range: 51~77) before operation and to $94.1{\pm}6.8$ points (range: 68~98) at the last follow up (p<0.05). 22 cases (69%) were evaluated normal (A), 9 cases (28%) were evaluated nearly normal (B) and only 1 case (3%) was evaluated not normal (C) at IKDC final evaluation and no case was evaluated abnormal. From $Telos^{(R)}$ stress x-ray evaluation, difference from the opposite knee was improved average 13.2 mm{\pm}5.8 (range: 6~21 mm) to average $3.4\;mm{\pm}2.8$ (range: 0~11 mm) after operation (p<0.05). The femoral and tibial tunnel were widened by 18.7% and 9.6% in the AP view and 12.4% and 8.5% in the lateral view, respectively (p<0.05). However, any statistic significance was not observed between bone tunnel expansion and knee joint functions (p>0.05). Conclusion: An ACL reconstruction with tibialis allograft using Hybrid femoral fixation and $Retroscrew^{(R)}$ enabled anatomical fixation of the graft tendon with satisfactory clinical results.

• Journal of Chest Surgery
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• v.37 no.1
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• pp.1-10
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• 2004

Background: Currently, the cardiopulmonary machine with non-pulsatile pumps, which are low in internal circuit pressure and cause little damage to blood cells, is widely used. However, a great number of experimental studies shows that pulsatile perfusions are more useful than non-pulsatile counterparts in many areas, such as homodynamic, metabolism, organ functions, and micro-circulation. Yet, many concerns relating to pulsatile cardiopulmonary machines, such as high internal circuit pressure and blood cell damage, have long hindered the development of pulsatile cardiopulmonary machines. Against this backdrop, this study focuses on the safety and effectiveness of the pulsatile cardiopulmonary machines developed by a domestic research lab. Material and Method: The dual-pulsatile cardiopulmonary bypass experiment with total extracorporeal circulation was conducted on six calves, Extracorporeal circulation was provided between superior/inferior vena cava and aorta. The membrane oxygenator, which was placed between the left and right pumps, was used for blood oxygenation. Circulation took four hours. Arterial blood gas analysis and blood tests were also conducted. Plasma hemoglobin levels were calculated, while pulse pressure and internal circuit pressure were carefully observed. Measurement was taken five times; once before the operation of the cardiopulmonary bypass, and after its operation it was taken every hour for four hours. Result: Through the arterial blood gas analysis, PCO2 and pH remained within normal levels. PO2 in arterial blood showed enough oxygenation of over 100 mmHg. The level of plasma hemoglobin, which had total cardiopulmonary circulation, steadily increased to 15.87 $\pm$ 5.63 after four hours passed, but remained below 20 mg/㎗. There was no obvious abnormal findings in blood test. Systolic blood pressure which was at 97.5$\pm$5.7 mmHg during the pre-circulation contraction period, was maintained over 100 mmHg as time passed. Moreover, diastolic blood pressure was 72.2 $\pm$ 7.7 mmHg during the expansion period and well kept at the appropriate level with time passing by. Average blood pressure which was 83$\pm$9.2 mmHg before circulation, increased as time passed, while pump flow was maintained over 3.3 L/min. Blood pressure fluctuation during total extracorporeal circulation showed a similar level of arterial blood pressure of pre-circulation heart. Conclusion: In the experiment mentioned above, pulsatile cardiopulmonary machines using the doual-pulsatile structure provided effective pulsatile blood flow with little damage in blood cells, showing excellence in the aspects of hematology and hemodynamic. Therefore, it is expected that the pulsatile cardiopulmonary machine, if it becomes a standard cardiopulmonary machine in all heart operations, will provide stable blood flow to end-organs.

• Journal of Climate Change Research
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• v.2 no.1
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• pp.15-32
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• 2011

Due to greenhouse gas increased by human activities, abnormal climate changes are continuously occurring everywhere in the world and internationally people make efforts to reduce the emission of greenhouse gas. Our country also is making endeavors to realize low carbon society on the foundation of the green growth and for this low carbon consumption pattern settlement through green life is necessary. Therefore for the nationals the offering of the information on greenhouse gas emission that is reduced through the change to low carbon life is required. In this study the objects are beef and wine whose weight of import is high among the beverages and foods consumed in the country and we calculated the food mileage and emission of carbon dioxide of the domestic and foreign product beef and wine and estimated the potential amount that can be reduced when replacing the imported products with domestic products. As the year 2007 being standard if we replace 10% of imported beef with domestic products it is possible to reduce 14,000 tons of carbon dioxide per year and on one day out of a year if we replace imported beef with domestic beef the reduction of 384 tons of carbon dioxide is appeared to be possible. In the same standard year if we replace 10% of imported wine with domestic product we can reduce 1,396 tons and on one day out of a year if we replace imported wine with domestic wine reduction of 38 tons of carbon per year appeared to be possible. Through active promotion and expansion of variety of domestic foods and beverages in the real life of the nationals the consumption pattern of natural low carbon life should be achieved and offering of more systematized greenhouse gas emission DB is thought to be necessary.