• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2007년도 추계학술대회 논문집
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• pp.489-492
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• 2007

Understanding the thermohydraulic processes in the aquifer is necessary for a proper design of the aquifer thermal energy utilization system under given conditions. Experimental and numerical test were accomplished to evaluate the relationship between the geothermal heat exchanger operation and hydrogeological conditions in the open-loop geothermal system. Sand tank experiments were designed to investigate the open-loop geothermal system. Water injection and extract ion system as open-loop borehole heat exchanger was applied to observe the temperature changes in time at injection well, extraction well and ambient groundwater. The thermohydraulic transfer for heat storage was simulated using FEFLOW for two cases of extraction and injection phase operation in sand tank model. As one case, the movement of the thermal plume was simulated with variable locations of injection and extraction well. As another case, the simulation was performed with fixed location of injection and extraction well. The simulation and experimental results showed that the temperature distribution depends highly on the injected water temperature and the length of injection time and the groundwater flow and pumping rate sensitively affect the heat transfer.

• 약학회지
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• 제39권3호
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• pp.283-288
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• 1995

Rapid gas chromatographic profiling method was applied to saliva from healthy subjects for the analysis of free organic acids. Saliva samples were first saturated with NaHCO$_{3}$ and extracted with diethyl ether. The aqueous phase was solid-phase extracted using Chromosorb P as the adsorbent and diethyl ether as the eluent after the acidification and NaCl saturation, followed by triethylamine treatment. The resulting tiiethylammonium salts of acids were directly converted into stable tert.-butyl-dimethylsflyl derivatives, with subsequent analysis by dual-capiuary column gas chromatography and gas chromatograpy -mass spectrometry. From the ten saliva samples studied, twenty eight free organic acids including various fatty acids, hydroxy acids, dicarboxylic acids, md aromatic acids were tentatively identified. Among the acids identified , the concentration of lactic acid was highest for five saliva samples while $\alpha$-hydroxyisocaproic acid was most abundant for me sample, and succinic acid and glycolic acid for two samples. respectively. When the GC profiles were simplified to the corresponding acid retention index spectra of bar graphical form, they presented characteristic patterns for each individual.

• Archives of Pharmacal Research
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• 제27권1호
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• pp.1-12
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• 2004

Initial burst is one of the major challenges in protein-encapsulated microparticle systems. Since protein release during the initial stage depends mostly on the diffusional escape of the protein, major approaches to prevent the initial burst have focused on efficient encapsulation of the protein within the microparticles. For this reason, control of encapsulation efficiency and the extent of initial burst are based on common formulation parameters. The present article provides a literature review of the formulation parameters that are known to influence the two properties in the emulsion-solvent evaporation/extraction method. Physical and chemical properties of encapsulating polymers, solvent systems, polymer-drug interactions, and properties of the continuous phase are some of the influential variables. Most parameters affect encapsulation efficiency and initial burst by modifying solidification rate of the dispersed phase. In order to prevent many unfavorable events such as pore formation, drug loss, and drug migration that occur while the dispersed phase is in the semi-solid state, it is important to understand and optimize these variables.

• 한국식품과학회지
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• 제33권3호
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• pp.282-287
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• 2001

인삼 조사포닌을 기존의 고온 MeOH 추출/n-BuOH 분획법 및 고온 MeOH 추출/Diaion HP-20 흡착/MeOH 용출법과 새로이 시도된 고온 MeOH 추출/cation AG 50W흡착/$H_2O$ 용출/n-BuOH 추출법(AG 50W법), 상온 MeOH 추출/Diaion HP-20 흡착/MeOH 용출법(상온추출법)과 EtOAc/n-BuOH 직접 추출법으로 분리한 다음 기존의 HPLC/RI 방법으로 ginsenoside조성을 비교한 결과 EtOAc/n-BuOH 직접 추출법을 제외하고는 큰 차이가 없었으나 분리능과 감도가 우수한 HPLC/ELSD방법을 사용한 결과, ginsenoside $Rb_2$, Rf, $Rg_1$ 및 $Rh_1$ 등을 뚜렷이 식별할 수 있었고 추출 및 분획방법에 따라 조사포닌간 ginsenoside의 현저한 조성차이를 볼 수 있었다. 특히 AG 50W법에 의해 분리된 조사포닌에서 뚜렷한 prosapogenin 피크를 볼 수 있었으며 LC/MS의 결과, ginsenoside $Rb_1$, $Rb_2$ 등의 7종의 주종 사포닌 이외에도 5종의 prosapogenin과 1종의 chikusetsusaponin을 포함한 총 13종의 ginsenoside를 동정하였다. 새로이 정립한 HPLC 분석조건, 즉 $NH_2$ 대신에 $C_{18}$ column을 사용하고 $KH_2PO_4/CH_3CN$ gradient로 상온추출법으로 분리한 조사포닌을 분석한 결과, malonyl ginsenoside 피크를 용이하게 확인할 수 있었다.

• 자원리싸이클링
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• 제26권1호
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• pp.51-58
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• 2017

TBP(tributyl phosphate)를 사용하여 왕수 침출액으로부터 질산과 금을 추출하여 회수하는 공정을 개발하기 위한 기초연구가 수행되었다. 순수한 왕수용액으로부터 추출제의 농도, 질산과 염산의 농도 비에 따른 질산의 추출거동을 조사하였으며, 금을 함유하는 왕수용액으로부터 질산과 금의 추출율을 구하였다. McCabe-Thiele 도로부터 얻어진 조업단수와 상비로 역류추출을 행하여 이론적인 추출단수를 검증하였다. 유기상에 장진된 질산과 금의 연속적인 회수를 위한 탈거실험을 수행하였다. 질산과 금의 추출과 염산의 영향을 고려하여 O/A = 1:0.85의 조건으로 역류추출을 통해 2단에 의해 $103.0mg{\cdot}L^{-1}$의 금은 99.9% 추출되었으며, 3단에 의해 $151.2g{\cdot}L^{-1}$의 질산은 98.0% 추출되었다. 질산과 금의 탈거제로는 증류수와 티오황산나트륨이 사용되었으며 탈거율은 각각 99.5%, 92.0%이었다. 이와 같은 연구결과로 왕수용액에 함유되어 있던 금과 질산을 동시에 추출하고 연속적인 탈거공정에 의해서 질산과 금을 회수하는 것이 가능함을 확인하였다.

• Journal of the Optical Society of Korea
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• 제14권3호
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• pp.240-244
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• 2010

In this work, we used PWM sampling for demodulation of a fiber-optic interferometric current transformer. The interference signal from a fiber-optic CT is sampled with PWM triggers that produce a 90-degree phase difference between two consecutively sampled signals. The current-induced phase is extracted by applying an arctangent demodulation and a phase unwrapping algorithm to the sampled signals. From experiments using the proposed demodulation, we obtained phase measurement accuracy and a linearity error, in AC current measurements, of ~2.35 mrad and 0.18%, respectively. The accuracy of the proposed method was compared with that of a lock-in amplifier demodulation, which showed only 0.36% difference. To compare the birefringence effects of different fiber-optic sensor coils, a flint glass fiber and a standard single-mode fiber were used under the same conditions. The flint glass fiber coil with a Faraday rotator mirror showed the best performance. Because of the simple hardware structure and signal processing, the proposed demodulation would be suitable for low-cost over-current monitoring in high voltage power systems.

• 정보학연구
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• 제7권1호
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• pp.155-161
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• 2004

정상적인 기계의 동작동안, 부분방전측정이 고전압전동기 고정자권선을 모의하여 터빈제너레이터 분석기(TGA)를 이용하여 실행하였다. 모의한 고정자권선에 인가된 전압은 4.47[kV]와 6.67[kV]을 인가하였다. 모의 고정자권선을 갖는 전동기들은 단자함에 80[pF]용량성 커풀러를 설치하였다. 인가전압 위상각을 고려한 부분방전패턴의 경우 2차원, 3차원적으로 보여주었다. TGA는 정규화된 펄스수(NGN)DHK 부분방전펄스크기(Qm)으로서 두개의 정량화된량을 나타내었다. 결론적으로, 우리는 모의한 고정자권선에 대한 내부방전과 표면방전의 차이를 TGA을 이용하여 식별할 수 있었다. 고정자권선의 결함에 대한 특징을 추출하기 위한 기법으로서 이산웨이블렛 변환기법 및 주파수분석법을 이용하여 결함신호에 대한 특징을 추출할 수 있었다.

• 자원환경지질
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• 제38권6호
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• pp.699-705
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• 2005

폐광된 장풍광산의 풍화된 폐광석에 함유된 중금속의 존재형태를 규명하기 위해 5단계 연속추출법을 수행하였다. 각 단계에서 용출된 용액은 ICP-AES로 분석하였다. XRD로 풍화된 폐광석 시료들의 광물조성을 파악한 결과, 시료는 산성 환경에서 pH에 대한 완충작용을 할 수 있는 방해석의 유무에 따라 두 유형(type I and type II)으로 나눌 수 있었다. Type I 시료의 주 구성광물은 석영으로 방해석이 산출되지 않으며, type II 시료의 주 구성광물은 방해석이었다. 모든 시료에서 비소, 코발트, 철은 잔류형태로 존재하는 것이 가장 우세하였다. 카드뮴, 망간, 아연의 경우 type I 시료에서는 잔류형태가, type II 시료에서는 산화철망간형태가 우세하였다. 구리는 type I 시료의 경우 잔류형태가 가장 우세하였고, type II의 경우 황화광물형태가 우세하였다. 납은 type I시료에서는 잔류형태가 가장 우세하였고, type II시료에서 산화철망간 형태가 우세하였다. pH 4-7 사이에서 중금속의 상대적인 이동성은 type I시료의 경우 아연>구리>카드뮴>납>코발트>비소의 순서였으며, type II시료에서는 카드뮴>구리>아연>납>비소>코발트의 순서로 확인되었다.

• Journal of Microbiology and Biotechnology
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• 제22권3호
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• pp.339-342
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• 2012

This study describes the characterization of a new angiotensin I-converting enzyme (ACE) inhibitory peptide from a Korean traditional rice wine. After purification of the ACE inhibitor peptides with ultrafiltration, Sephadex G-25 column chromatography, and successively $C_{18}$ and SCX solid-phase extraction, reverse-phase HPLC, and size exculsion chromatography, two types of the purified ACE inhibitors with $IC_{50}$ values of 0.34 mg/ml and 1.23 mg/ml were finally obtained. The two purified ACE inhibitors (F-1 and F-2) were found to have two kinds of novel oligopeptides, showing very little similarity to other ACE inhibitory peptide sequences. The amino acid sequences of the two purified oligopeptides were found to be Gln-Phe-Tyr-Ala-Val (F-1) and Ala-Gly-Pro-Val-Leu-Leu (F-2), and their molecular masses were estimated to be 468.7 Da (F-1) and 357.7 Da (F-2), respectively. They all showed a clear antihypertensive effect on spontaneously hypertensive rats at a dosage of 500 mg/kg.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2008년도 추계학술대회B
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• pp.2664-2669
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• 2008

Feedwater heaters of many nuclear power plants have recently experienced severe wall thinning damange, which will increase as operating time progresses. Several nuclear power plants in Korea have experienced wall thinning damage in the area around the impingement baffle-installed downstream of the high pressure turbine extraction stream line- inside number 5A and 5B feedwater heaters. At that point, the extracted steam from the high pressure turbine is two phase fluid at high temperature, high pressure, and high speed. Since it flows in reverse direction after impinging the impingement baffle, the shell wall of the number 5 high pressure feedwater heater may be affected by flow-accelerated corrosion. This paper describes operation of experience and numerical analysis composed similar condition with real high pressure feedwater heater. This study applied squared, curved and new type impingement baffle plates to feedwater heater same as previous study. In addition, it shows difference of pressure distribution and value between single phase and two phase based on experience and numerical analysis.