• 제목/요약/키워드: Tolerance control

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1형과 2형 당뇨모델 흰쥐에서 Chromium Picolinate의 당내성과 인슬린 감수성에 대한 영향 (Effect of Chromium Picolinate on Glucose Tolerance and Insulin Sensitivity in the Type I and II Diabetic Rats)

  • 신현진;홍정희;고현철;신인철;강주섭;최호순;김태화;김동선;엄애선
    • Biomolecules & Therapeutics
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    • 제9권4호
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    • pp.277-281
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    • 2001
  • Chromium is an essential nutrient and participates in glucose and lipid metabolism in human beings and animals. The present study was conducted to assess the effects of chromium picolinate (Cr-pic) on glucose tolerance and insulin sensitivity in type I and ll diabetic rats. The experimental groups were type I diabetic (streptozotocin-induced: 40 mg/kg, i.p.) and type II diabetic (Goto-Kakizaki rats) models. Each group was subdivided into control. low-dose and high-dose of Cr-pic treated groups. The Cr-pic was orally administered with Cr-pic (100 mg/kg for low dose group and 200 mg/kg for high dose group) for 4 weeks. And then we performed intraperitoneal glucose tolerance test (IPGTT) and insulin sensitivity test (ITT). The glucose tolerance test was carried out by inection of glucose (2 g/kg, i.p.). The peripheral insulin sensitivity test was con- ducted by injection of insulin (5 units/kg, s.c.) and glucose. We performed determining of blood glucose concentration at 0, 10, 30, 60, 90, and 120 min using automated glucose analyzer. The plasma insulin concentration was determined by rat insulin EIA kit. Administration of Cr-pic improved weight gain in all group s with higher significant in the low-dose group. There was no significance between the control and the Cr-pic treated groups in the area under the blood glucose curve and serum insulin concentration plots of IPGTT and peripheral ITT in type I diabetic rats. But Cr-pic treated groups showed significantly lower levels of the area under the blood glucose currie during IPGTT and ITT and the high-dose group showed less effects compared with the low-dose group in the type II diabetic rats. The plasma insulin concentration of both diabetic groups was not influenced by Cr-pic supplementation. We can conclude that chromium picolinate may improve the endogenous and exogenous insulin action and peripheral insulin sensitivity in type II diabetic rats.

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Evaluation of Drought Tolerance for Biomass Production of Salix gracilistyla Miq.

  • Hyun Jin Song;Seong Hyeon Yong;Hak Gon Kim;Kwan Been Park;Do Hyeon Kim;Seung A Cha;Ji Hyun Lee;Myung Suk Choi
    • Journal of Forest and Environmental Science
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    • 제39권4호
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    • pp.246-253
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    • 2023
  • Salix gracilistyla is widely distributed along riversides in Korea and very good for biomass production by SRC because of its excellent germination ability, but it is necessary to measure drying tolerance for cultivation. The drought tolerance of S. gracilistyla was tested using cuttings, and growth and physiological analysis were performed after irrigation was stopped. The growth inhibition of S. gracilistyla was observed from the day irrigation was stopped, and the soil moisture content decreased to less than 10% on the 25th day after irrigation was stopped. Over 50% of the seedlings turned brown 25 days after watering was stopped. The chlorophyll content of S. gracilistyla decreased dramatically after 25 days of stopping of irrigation. RWC values were unchanged until day 12 after irrigation was stopped but decreased rapidly until day 21, but there was a slightly decreasing trend after that. RWL levels increased slightly during irrigation stops. The proline content of plants subjected to drought stress was 0.91-2.63 mg/0.05 g, 2.75 times higher than that of the control treatment. The sugar content of the drought stress treatment group was 29.77 to 350.66 mg/0.05 g, which increased 12.24 times that of the control treatment. As a result of this study, S. gracilistyla was found to have a drought tolerance almost comparable to that of evergreen broad-leaved trees growing on the land. This study is expected to contribute to the resource utilization S. gracilistyla, a native willow tree of Korea, and the mass production of biomass by SRC.

급격한 저염분 노출에 따른 참돔 Pagrus major 치어의 단기 행동반응 및 내성 한계에 관한 연구 (Short-term behavioral responses and tolerance limits of red seabream Pagrus major fingerlings following sudden low salinity exposure)

  • 윤성진
    • 환경생물
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    • 제39권4호
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    • pp.495-506
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    • 2021
  • In this study, using a continuous behavior measurement technique, the short-term behavioral responses and tolerance limits of red seabream Pagrus major fingerlings to sudden exposure to low salinity in a controlled environment were observed. The activity of the fingerlings suddenly exposed to 21.4, 17.3, and 9.8 psu increased temporarily at the initial exposure to show irregular swimming behavior, but then recovered a stable activity pattern through rapid salinity adaptation. However, the organisms suddenly exposed to 7.3 and 4.3 psu could not withstand the salinity stress, and their swimming behavior was severely disturbed and all individuals died within 48 hours. The findings suggest that red seabream underwent a temporary salinity stress process at the beginning of the exposure to concentrations of 10.0 psu or higher. At these concentrations, osmotic control was possible within at least 11 hours, so stable metabolic activity was also possible. However, organisms suddenly exposed to concentrations below 5.0 psu exceeded the tolerance to low salinity and the sublethal limit. In red seabream exposed to this concentration range, severe behavioral and metabolic disturbances were observed, and death was observed due to osmotic control failure. In conclusion, a salinity range of 5.0 to 10.0 psu can be predicted to correspond to a concentration range in which the osmotic control ability of the red seabream fingerlings is lost, and sub-lethal reactions occur.

Screening methods for drought and salinity tolerance with transgenic rice seedlings

  • Song, Jae-Young;Song, Seon-Kyeong;Yu, Dal-A;Kim, Me-Sun;Kang, Kwon Kyoo;Cho, Yong-Gu
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2017년도 9th Asian Crop Science Association conference
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    • pp.165-165
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    • 2017
  • Abiotic stress is one of the major serious limiting factors in rice (Oryza sativa) and caused rice production losses. It is important to precisely screen valuable genetic resources for improving stress tolerance and understanding tolerance mechanism to abiotic stresses. Because there are differences of experiment designs for screening of tolerant plant in several studies related to abiotic stress, this study has performed to provide the rapid and efficiency screening method for selection of tolerance rice to drought and salinity stresses. Two week-old rice seedlings that reached about three leaf stage were treated with drought and salinity stresses and examined tolerant levels with tolerant and susceptible control varieties, and transgenic plants. To determine the optimum concentration for the selection of drought and salinity condition, tolerant, susceptible and wild-type plants were grown under three soil moisture contents (5, 10 and 20% water contents) and three NaCl concentrations (100, 200 and 250 mM) for 10 days at seedling stage. 200 mM NaCl concentration and 5% moisture content soil were determined as the optimum conditions, respectively. The described methodologies in this study are simple and efficiency and might help the selection of drought and salinity tolerance plants at the 3,4-leaf-seedling stage.

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Physiological and Genetic Responses of Salt-stressed Tunisian Durum (Triticum turgidum ssp. durum) Cultivars

  • Kim, Sang Heon;Kim, Dae Yeon;Yacoubi, Ines;Seo, Yong Weon
    • 한국작물학회지
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    • 제63권4호
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    • pp.314-321
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    • 2018
  • Durum (Triticum turgidum L. ssp. durum) is a major crop species cultivated for human consumption worldwide. In Tunisia, salt stress is one of the main problems that limit crop production. 'Mahmoudi' was selected as the most salt-sensitive out of 11 Tunisian durum cultivars. Using the salt-tolerant cultivar 'Om Rabia', resistant and susceptible cultivars were evaluated to compare genetic responses under salt stress. At the fully expanded third leaf stage, salt stress was applied by submerging the pots in 500 mM NaCl for 5 min every day for saline water irrigation in the greenhouse. The treatment was applied for 1 week and salt stress tolerance was determined by changes of growth parameters to the control condition. The salt tolerance trait index and salt tolerance index were calculated and used as selection criteria. The expression levels of TdHKT1;4, TdHKT1;5, and TdSOS1 were examined using qPCR. For further evaluation of physiological responses, salt stress (150 mM NaCl) was additionally applied for 48 h at the fully expanded third-leaf stage. Increased expression of the genes responsible for salt tolerance and proline content in tolerant durum can be used to broaden genetic diversity and provide genetic resources for the durum breeding program.

벼 일품벼/모로베레칸 조합의 이입계통을 이용한 내건성 유전자 탐지 (Mapping QTLs for drought tolerance using an introgression line population from a cross between Ilpumbyeo and Moroberekan in rice)

  • 강주원;구홍광;양바오로;안상낙
    • 농업과학연구
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    • 제38권2호
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    • pp.199-204
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    • 2011
  • This study was conducted to map quantitative trait loci (QTLs) related to drought stress tolerance. An introgression line population derived from a cross, "Ilpum" / "Moroberekan" was used in this study. $F_1$ plants were backcrossed three times to Ilpum to produce $BC_3F_1$ plants. These plants were advanced by selfing for four generation and a total of 117 $BC_3F_5$ introgression lines were developed. These lines were evaluated for percent seed set and spikelets per panicle under the control (field) and drought condition. To identify QTLs related to drought tolerance, 134 SSR markers showing polymorph isms between the parents were genotyped for the 117 $BC_3F_5$ lines. A total of 6 QTLs associated with drought stress were detected on chromosomes 1, 3, 4, 7 and 10. These include two QTLs for phenotypic acceptability, two QTLs for percent seed set ($R^2$ = 19.0 - 20.9%), and two QTLs for spikelets per panicle ($R^2$ = 22.3 - 23.10%). The Moroberekan alleles at three loci contributed the positive effect for drought tolerance. The SSR markers linked to drought stress tolerance can not only facilitate the selection of valuable genes from Moroberekan, but also allow identification of lines with drought tolerance.

변화대응 및 업무적응에 대한 긍정적 자기관과 모험 수용성의 영향 (Effects of Change Agent\`s Positive Self Image and Risk Tolerance on Change Acceptance and Work Adaptation)

  • 이주일;이경옥
    • 한국조사연구학회:학술대회논문집
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    • 한국조사연구학회 2000년도 춘계학술대회 조사연구의 방법론적 쟁점
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    • pp.59-87
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    • 2000
  • 기업체에서 변화 활동을 담당하는 변화 담당자 305명을 대상으로 이들의 자기관, 모험 수용성과 같은 성격특성이 조직이 추진하는 변화활동 및 담당업무에 대한 적용에 미치는 효과를 살펴보았다. 연구 결과, 긍정적인 자기관과 모험 수용성이 높은 사람들은 조직이 추진하고 있는 변화 활동관련 업무를 보다 적극적으로 수행하고 있었으며, 담당하는 변화관련 업무에 대한 적응도가 높은 것으로 나타났다. 또한 변화대응성은 긍정적인 자기관 및 모험 수용성과 업무에 대한 적응간을 매개하는 변수역할을 원활하게 수행하기 위해서는 긍정적인 자기관과 모험 수용성을 보유하는 것이 필요하며, 조직에서 변화 담당자를 선발하고 이들을 교육할 때 이들의 자기관을 긍정적으로 변화시켜주고, 모험 수용성을 높여주는 것(또는 이런 성향이 높은 사람을 선발하는 것)이 바람직함을 시사한다. 또한 변화담당자들이 자신들이 담당하는 업무에 쉽게 적응하도록 하기 위해서는 이들의 변화대응성을 높이는 것이 필요함을 시사한다.

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변화대응 및 업무적응에 대한 긍정적 자기관과 모험 수용성의 영향 (Effects of Change Agent's Positive Self Image and Risk Tolerance on Change Acceptance and Work Adaptation)

  • 이주일;이경옥
    • 한국조사연구학회지:조사연구
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    • 제1권2호
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    • pp.59-87
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    • 2000
  • 기업체에서 변화 활동을 담당하는 변화 담당자 305명을 대상으로 이들의 자기관, 모험 수용성고 같은 성격특성이 조직이 추진하는 변화활동 및 담당업무에 대한 적응에 미치는 효과를 살펴보았다. 연구결과, 긍정적인 자기관과 모험 수용성이 높은 사람들은 조직이 추진하고 있는 변화활동관련 업무를 보다 적극적으로 수행하고 있었으며, 담당하는 변화관련 업무에 대한 적응도가 높은 것으로 나타났다. 또한 변화대응성은 긍정적인 자기관 및 모험 수영성과 업무에 대한 적응간을 매개하는 변수역할을 하는 것으로 나타났다. 본 연구결과는 변화담당자가 조직에서 추진하는 변화관련 업무를 원활하게 수행하기 위해서는 긍정적인 자기관과 모험 수용성을 보유하는 것이 필요하며, 조직에서 변화 담당자를 선발하고 이들을 교육할 때 이들의 자기관을 긍정적으로 변화시켜주고, 모험 수용성을 높여주는 것(또는 이런 성향이 높은 사람을 선발하는 것)이 바람직함을 시사한다. 또한 변화담당자들이 자신들이 담당하는 업무에 쉽게 적응하도록 하기 위해서는 이들의 변화대응성을 높이는 것이 필요함을 시사한다.

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절삭공정에서 Fault-tolerance 기능을 갖는 지능형 감시 및 제어시스템의 개발 (Development of a Fault-tolerant Intelligent Monitoring and Control System in Machining)

  • 최기흥
    • 대한기계학회논문집A
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    • 제21권3호
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    • pp.470-476
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    • 1997
  • The dynamic characteristics of industrial processes frequently cause an abnormal situation which is undesirable in terms of the productivity and the safety of workers. The goal of fault-tolerance is to continue performing certain activities even after the failure of some system cononents. A fault-tolerant intelligent monitoring and control system which is robust under disturbances is proposed in this paper. Specifically, the fault-tolerant monitoring scheme proposed consists of two process models and the inference module to preserve such a robustness. The results of turning experiments demonstrate the effectiveness of the fault-tolerant scheme in the presence of built-up edge.

인터리빙 구조를 갖는 메모리의 스크러빙 기법 적용에 따른 신뢰도 해석 (Reliability Analysis of Interleaved Memory with a Scrubbing Technique)

  • 류상문
    • 제어로봇시스템학회논문지
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    • 제20권4호
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    • pp.443-448
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    • 2014
  • Soft errors in memory devices that caused by radiation are the main threat from a reliability point of view. This threat can be commonly overcome with the combination of SEC (Single-Error Correction) codes and scrubbing technique. The interleaving architecture can give memory devices the ability of tolerating these soft errors, especially against multiple-bit soft errors. And the interleaving distance plays a key role in building the tolerance against multiple-bit soft errors. This paper proposes a reliability model of an interleaved memory device which suffers from multiple-bit soft errors and are protected by a combination of SEC code and scrubbing. The proposed model shows how the interleaving distance works to improve the reliability and can be used to make a decision in determining optimal scrubbing technique to meet the demands in reliability.