• Title/Summary/Keyword: Tm3+

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Effectiveness of Telemonitoring Intervention in Children and Adolescents with Asthma: A Systematic Review and Meta-Analysis (천식 아동 및 청소년에서 원격모니터링 중재의 효과: 체계적 문헌고찰 및 메타분석)

  • Jung, Youjin;Kim, Jimin;Park, Dong Ah
    • Journal of Korean Academy of Nursing
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    • v.48 no.4
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    • pp.389-406
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    • 2018
  • Purpose: This review aimed to evaluate the effectiveness of telemonitoring (TM) in the management of children and adolescents with asthma. Methods: We searched Ovid-MEDLINE, Ovid-EMBASE, CENTRAL (Cochrane Central Register of Controlled Trials), CINAHL (Cumulative Index to Nursing and Allied Health Literature), and 5 domestic databases to identify randomized controlled trials (RCTs) published through December 2017. Two reviewers independently selected relevant studies, assessed methodological quality and extracted data. We performed a meta-analysis of TM versus usual care and summarized the intervention characteristics of included studies. Results: Of the 3,095 articles identified, 8 RCTs (9 articles) were included in this review. The type of TM intervention of included studies was varying across studies (transmitted data, transmission frequency, data review, etc.). The pooled asthma control score was not significantly different between TM and usual care (standardized mean difference 0.04, 95% confidence interval (CI) -0.20~0.28). Another pooled analysis demonstrated no statistically significant difference in asthma exacerbation between TM and usual care (odds ratio 0.95, 95% CI 0.43~2.09). Overall, the pooled results from these studies revealed that TM did not lead to clinically significant improvements in health outcomes, but some studies in our analysis suggested that TM increased patient medication adherence and intervention adherence. Conclusion: The current evidence base does not demonstrate any differences between TM intervention and usual care, but TM intervention might be considered a promising strategy for the delivery of self-management support for children and adolescents with asthma. Further well-designed studies are needed to assess the effects on clinical outcomes.

SHEAR BOND STRENGTH OF HEAT-CURED DENTURE BASE RESIN TO SURFACE TREATED CO-CR ALLOY WITH DIFFERENT METHODS (코발트-크롬 합금의 표면처리에 따른 열중합형 의치상용 레진과의 전단결합강도)

  • Lee, Sang-Hoon;Hwang, Sun-Hong;Moon, Hong-Seok;Lee, Keun-Woo;Shim, June-Sung
    • The Journal of Korean Academy of Prosthodontics
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    • v.45 no.2
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    • pp.216-227
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    • 2007
  • Statement of problem: For the long-term success of removable partial dentures, the bonding between metal framework and denture base resin is one of the important factors. To improve bonding between those, macro-mechanical retentive form that is included metal framework design has been generally used. However it has been known that sealing at the interface between metal framework and denture base resin is very weak, because this method uses mechanical bonding. Purpose: Many studies has been made to find a simple method which induces chemical bond, now various bonding system is applied to clinic. In this experiment, shear bond strengths of heat-cured denture base resin to the surface-treated Co-Cr alloy were measured before and after thermocycling. Chemically treated groups with Alloy $Primer^{TM}$, Super-Bond $C&B^{TM}$, and tribochemically treated group with $Rocatec^{TM}$ system were compared to the beadtreated control group. The data were analyzed with two-way ANOVA. Result: 1. Shear bond strength of bead-treated group is highest, and Alloy $Primer^{TM}$ treated group, Super-Bond $C&B^{TM}$ treated group, RocatecTM system treated group were followed. Statistically significant differences were found in each treated group(p<0.05). 2. Surface treatment and thermocycling affected shear bond strength(p<0.05), however there was no interaction between two factors(p>0.05). 3. Shear bond strengths of bead-treated group and Alloy $Primer^{TM}$ treated group showed no statistically significant difference before and after thermocycling(p>0.05), and those of Super-Bond $C&B^{TM}$ treated group and $Rocatec^{TM}$ system treated group showed statistically significant difference after thermocycling(p<0.05).

Classification of Crop Lands over Northern Mongolia Using Multi-Temporal Landsat TM Data

  • Ganbaatar, Gerelmaa;Lee, Kyu-Sung
    • Korean Journal of Remote Sensing
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    • v.29 no.6
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    • pp.611-619
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    • 2013
  • Although the need of crop production has increased in Mongolia, crop cultivation is very limited because of the harsh climatic and topographic conditions. Crop lands are sparsely distributed with relatively small sizes and, therefore, it is difficult to survey the exact area of crop lands. The study aimed to find an easy and effective way of accurate classification to map crop lands in Mongolia using satellite images. To classify the crop lands over the study area in northern Mongolia, four classifications were carried out by using 1) Thematic Mapper (TM) image August 23, 2) TM image of July 6, 3) combined 12 bands of TM images of July and August, and 4) both TM images of July and August by layered classification. Wheat and potato are the major crop types and they show relatively high variation in crop conditions between July and August. On the other hands, other land cover types (forest, riparian vegetation, grassland, water and bare soil) do not show such difference between July and August. The results of four classifications clearly show that the use of multi-temporal images is essential to accurately classify the crop lands. The layered classification method, in which each class is separated by a subset of TM images, shows the highest classification accuracy (93.7%) of the crop lands. The classification accuracies are lower when we use only a single TM image of either July or August. Because of the different planting practice of potato and the growth condition of wheat, the spectral characteristics of potato and wheat cannot be fully separated from other cover types with TM image of either July or August. Further refinements on the spatial characteristics of existing crop lands may enhance the crop mapping method in Mongolia.

The efficacy evaluation of $PostPlant^{TM}$ Calcium in dental implant placement (임플란트 식립 환자의 $PostPlant^{TM}$ Calcium 투여 효과에 대한 임상연구)

  • Choi, Yu-Sung;Kim, Eun-Kyung;Kim, Se-Won;Cho, In-Ho
    • The Journal of Korean Academy of Prosthodontics
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    • v.48 no.2
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    • pp.128-134
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    • 2010
  • Purpose: The aim of this study was to evaluate the changes in bone density and reduction of time consumed for osteogenesis by $PostPlant^{TM}$ Calcium and to find out efficacy of $PostPlant^{TM}$ Calcium by comparing the group prescribed with $PostPlant^{TM}$ Calcium with the group without $PostPlant^{TM}$ Calcium prescription. Material and methods: The experimental group of 18 patients with 25 dental implant placement and the control group of 7 patients with 9 dental implant placement were randomly selected from the patients who visited prosthetic department of Dankook University Dental Hospital since July, 2006 (IRB Number ; 20060710). The experimental group was instructed to take $PostPlant^{TM}$ Calcium for 6 months after the implant surgery while the control group was instructed not to. Both experimental and control group were assigned for measurement using $Osstell^{TM}$ Mentor and $Periotest^{(R)}$ and radiographic examination was performed using specifically manufactured Aluminum Step Wedge. The results were compared and analyzed. Results: 1. According to the $Osstell^{TM}$ Mentor measurement, both the experimental and control group showed increase in values as time elapses and the experimental group showed significantly higher rate of increase (P < .05). 2. According to the $Periotest^{(R)}$ measurement, both the experimental and control group showed decrease in values as time elapses. In addition, greater decrease can be seen in the experimental group but no statistical significance was found. 3. By examining the radiographic images, both the experimental and control group showed tendency of increase in bone density. In addition, greater increase can be seen in the experimental group but no statistical significance was found. Conclusion: Clinically, taking $PostPlant^{TM}$ Calcium medicine for a long period of time after implant placement is expected for a better prognosis.

Association Between the XRCC3 T241M Polymorphism and Head and Neck Cancer Susceptibility: a Meta-analysis of Case-control Studies

  • Yin, Qing-Hua;Liu, Chuan;Li, Lian;Zu, Xu-Yu;Wang, Ya-Jie
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.10
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    • pp.5201-5205
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    • 2012
  • Background: To evaluate the role of the X-ray repair cross complementing group 3 (XRCC3) T241M polymorphism in head and neck cancer susceptibility. Materials and Methods: We performed a meta-analysis of all available studies, which included 3,191 cases and 5,090 controls. Results: Overall, a significant risk effect of the T241M polymorphism was not found under homologous contrast (MM vs TT: OR=1.293, 95% CI=0.926-1.805; TM vs TT: OR=1.148 95% CI=0.930-1.418) and recessive models (MM vs TT+TM): OR=1.170, 95% CI=0.905-1.512, but a significantly increased risk was observed under a dominant model (MM+TM vs TT): OR=1.243, 95% CI=1.001-1.544. In stratified analyses, there were no significant associations for Asians or Caucasians. Conclusion: Our meta-analysis suggested the XRCC3 241M allele (MM+TM) might act as a head and neck cancer risk factor among all subjects, and the effect of T241M polymorphism on head and neck susceptibility should be studied with a larger, stratified population.

Protective effects Acanthopanax senticosus extracts on ethanol-induced apoptosis in TM3 mouse Leydig cells (오가피전탕액(五加皮煎湯液)이 에탄올에 의해 유발되는 TM3 mouse Leydig 세포주의 apoptosis에 미치는 영향)

  • Kim Jong-Chul;Kim Hee-Taek;Kim Ho-Hyun;Kim Ee-Hwa
    • Korean Journal of Acupuncture
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    • v.20 no.1
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    • pp.57-64
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    • 2003
  • 목적: 오가피가 mouse testis에서 유래된 Leydig 세포주에서 에탄올에 의해 유발된 아폽토시스에 미치는 영향을 조사하였다. 방법: TM3 세포주에서의 아폽토시스 변화를 관찰하기 위해서 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, 4,6-diamidino-2-phenylindole (DAPI), DNA fragmentation assay, 및 reverse transcription-polymerase chain reaction (RT-PCR) 방법을 이용하였다. 결과: MTT assay를 이용하여 분석한 결과 농도에 따른 세포독성의 효과가 에탄올 투여부터 관찰되었다. 또한 오가피로 전처치하고 에탄올을 처치하였을 때 세포독성이 크게 감소되었다. DAPI staining에서 오가피 투여군은 에탄올 투여군에 비해서 fragmentation이 억제되었다. RT-PCR의 분석에 의하여 caspase-3 mRNA 발현이 오가피 투여군은 알코올 투여군보다 유의성있게 억제됨을 보여주었다. 결론: TM3 Leydig 세포주에서 에탄올에 의해 유발된 아폽토시스는 전형적인 세포사멸 형태를 나타내었다. 반면에 오가피 투여군은 에탄올에 의해서 유발된 아폽토시스에서 세포보호 효과가 있음이 확인되었다.

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Effects of Bisphenol and Octylphenol on TM3 Cell : Expression of Cytochrome P450scc and Estrogen Receptor $\alpha$ mRNA (Bisphenol과 Octylphenol이 TM3 세포에 미치는 영향: Cytochrome P450scc와 Estrogen Receptor $\alpha$ 유전자의 발현)

  • 이호준;김묘경;강희규;김동훈;한성원;고덕성
    • Development and Reproduction
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    • v.4 no.2
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    • pp.215-220
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    • 2000
  • Most of endocrine disrupters (EDs) have been reported to exhibit estrogenic or anti-androgenic activity and thereby may disrupt reproductive development in human or wildlife. This study was performed to investigate the effects of estrogen (E$_2$), bisphenol (BP) and octylphenol (OP) on the mouse Leydig cell line (TM3). TM3 originated from testis of 11~13-daly-old BALB/c nu/+ mice was cultured in DMEM supplemented with 10% FBS alone or medium with estrogen (E$_2$), bisphenol (BP) and octylphenol (OP; 1 pM, 1 nM, 1 $\mu$M, 1 mM, respectively) for 48 hours. After culture, total cell number and viability were assessed by heamocyto-meter and trypan blue stain. Expression of cytochrome P450scc (CYPscc) mRNA whose product is involved in steroid hormone biosynthesis and estrogen receptor $\alpha$(ER $\alpha$) mRNA were detected by RT-PCR. As a result, treatment of TM3 with E$_2$, BP and OP(1 mM, respectively) significantly decreased the viability but not all of groups as high as 1 $\mu$M. Exposure of TM3 to OP significantly reduced the total cell number but not E$_2$ or BP. The expression of CYPscc mRNA was slightly reduced in BP (1 nM, 1 $\mu$M) and significantly decreased in OP (1 nM, 1 $\mu$M) treated TM3, except E$_2$ group. But the expression of ER $\alpha$ mRNA was sightly increased in all treated groups. In conclusion, BP and OP (high concentration) might inhibit steroidogenesis by decreasing the CYPscc mRNA expression in the mouse testis. These results suggest that BP and OP might impair spermatogenesis and subsequently disturb testicular function.

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Installation and Shipboard Tests of the Ballast Water Treatment System Electro-Cleen (Electro-Cleen 선박평형수 처리장치의 실선 설치 및 선상시험)

  • Kim, Eun-Chan;Cho, Jin-Suk;Park, Yong-Seok;Lee, Jong-Wook
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.12 no.3
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    • pp.209-216
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    • 2009
  • IMO has established International Convention for the Control and Management of Ships' Ballast Water and Sediment 2004 in February 2004 in order to prevent transfer of aquatic organisms through ballast water. According to the Convention, Each countries are preparing ratification and legislation process and encouraging the development of treatment system to satisfy the performance standard in the Convention. This Electro-$Cleen^{TM}$ treatment system was granted IMO basic approval in March 2006, and final approval in October 2008. The Type Approval Certificate was issued in December 2008 by the Government of Republic of Korea. This paper considers the matter of principle mechanism, overview of the system, installation on shipboard and shipboard test results for the Electro-$Cleen^{TM}$. Shipboard tests with the 8300 GT M/V Yokohama and 27,000 DWT M/V Greenwing have already been conducted. These tests confirmed that the Electro-$Cleen^{TM}$ system satisfies all of the IMO standards and is suitable for installation in new and existing ships.

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Evaluation of Dry Rehydratable Film Method for Enumeration of Microorganisms in Meat, Dairy and Fishery Products (축.수산식품 중 미생물 분석을 위한 건조필름법 평가)

  • Cho, Mi-Hee;Bae, Eun-Kyung;Ha, Sang-Do;Park, Young-Seo;Mok, Chul-Kyoon;Hong, Kwan-Pyo;Kim, Sang-Phil;Park, Ji-Yong
    • Korean Journal of Food Science and Technology
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    • v.37 no.2
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    • pp.294-300
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    • 2005
  • Contents of total aerobic bacteria, coliform, Escherichia coli, yeast, mold, and Staphylococcus aureus in meat, dairy, and fishery products were analyzed by dry rehydratable film method using 3M $Petrifilm^{TM}$ and compared against those obtained through conventional method. Two methods showed high correlations of 0.990-0.999, 0.975-0.999, 0.979-0.987, 0.978-0.984, and 0.999 for total aerobic bacteria, yeast and mold, coliform, E. coli, and S. aureus, respectively; therefore, dry rehydratable film method using 3M $Petrifilm^{TM}$ offers acceptable alternative to conventional method for enumeration of microorganisms in meat, dairy, and fishery products.