• 제목/요약/키워드: Threshold Effect

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Effect of 8% lidocaine spray on the sensory and pain thresholds of the skin of the face and hands evaluated by quantitative sensory testing

  • Okayasu, Ichiro;Komiyama, Osamu;Ayuse, Takao;De Laat, Antoon
    • Journal of Dental Anesthesia and Pain Medicine
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    • 제18권6호
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    • pp.361-365
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    • 2018
  • Background: Recently, we examined the effects of 2% lidocaine gel on the tactile sensory and pain thresholds of the face, tongue and hands of symptom-free individuals using quantitative sensory testing (QST); its effect was less on the skin of the face and hands than on the tongue. Consequently, instead of 2% lidocaine gel, we examined the effect of 8% lidocaine spray on the tactile sensory and pain thresholds of the skin of the face and hands of healthy volunteers. Methods: Using Semmes-Weinstein monofilaments, QST of the skin of the cheek and palm (thenar skin) was performed in 20 healthy volunteers. In each participant, two topical sprays were applied. On one side, 0.2 mL of 8% lidocaine pump spray was applied, and on the other side, 0.2 mL of saline pump spray was applied as control. In each participant, QST was performed before and 15 min after each application. Pain intensity was measured using a numeric rating scale (NRS). Results: Both the tactile detection threshold and filament-prick pain detection threshold of the cheek and thenar skin increased significantly after lidocaine application. A significant difference between the effect of lidocaine and saline applications was found on the filament-prick pain detection threshold only. NRS of the cheek skin and thenar skin decreased after application of lidocaine, and not after application of saline. Conclusion: The significant effect of applying an 8% lidocaine spray on the sensory and pain thresholds of the skin of the face and hands can be objectively scored using QST.

평결범주와 일반인의 법적판단: '무죄표상'의 역할을 중심으로 (The verdict category and legal decision: Focused on the role of representation of 'innocent')

  • 한유화
    • 한국심리학회지:법
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    • 제13권1호
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    • pp.1-22
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    • 2022
  • 본 연구는 국민참여재판의 평결범주가 일반인의 법적판단에 미치는 영향과 그 과정에서 '무죄표상'의 역할을 확인하였다. '무죄표상'은 일반적인 의미의 무죄(잘못이 없음)판단을 위한 심리적 기준을 의미한다. 또한, 법률로 정해진 유죄판단 기준으로 간주되는 '합리적 의심의 여지없는 유죄의 증명(beyond a reasonable doubt: BRD)'과 개인의 역치에 대한 추정치인 IT(individual threshold)의 역치로서의 기능을 비교하였다. 본 연구는 평결범주(유죄/무죄 vs. 유죄/유죄아님)와 피고인 유죄가능성(낮음 vs. 높음)을 각각 두 수준으로 조작한 2×2 완전교차요인설계를 사용하였으며, 온라인으로 진행되는 실험에 자발적으로 참여한 137명의 자료가 분석에 사용되었다. 실험은 '무죄표상' 및 기소유죄확률 측정, 재판시나리오 제시, 피고인에 대한 법적판단(판단 확신감 및 피고인 유죄가능성 추정 등 포함) 순으로 진행되었다. 연구 결과, 평결범주는 일반인의 법적판단에 유의한 영향을 미치지 못하는 것으로 나타났으나 '유죄/무죄'의 평결범주를 제시받은 경우 '유죄/유죄아님'의 평결범주를 제시받은 경우보다 유죄판단 비율이 높은 경향이 있었다. 일반인들의 '무죄표상'과 평결범주의 상호작용은 이론적 유죄판단 역치(BRD)와 개인의 역치(IT)의 차이(역치 변화량)를 잘 예측하는 것으로 나타났으며, '유죄/무죄'의 평결범주를 제시받은 경우에 '유죄/유죄아님'의 평결범주를 제시받은 경우보다 '무죄표상'의 변화에 따른 역치변화량이 더 컸다. 역치로서의 BRD와 IT를 비교한 결과에서는 IT가 유죄가능성과 상호작용하여 일반인의 법적판단을 유의하게(p<.1) 예측하는 것으로 나타나서 IT가 BRD보다 더 좋은 역치 추정치라고 할 수 있었다. 본 연구는 법률가들 사이에서 종종 제기되는 문제인 국민참여재판 평결범주의 효과를 실험을 통하여 확인하고 그 효과의 심리적 기제에 대한 논리적인 추론 및 경험적 근거를 제공하였다는 데 의의가 있다.

전력 VDMOSFET의 온도변화 특성에 관한 연구 (A Study on the Temperature Variation Characteristics of Power VDMOSFET)

  • Lee, Woo-Sun
    • 대한전기학회논문지
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    • 제35권7호
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    • pp.278-284
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    • 1986
  • Double-diffused metal oxide power semiconductor field effect transistors are used extensively in recent years in various circuit applications. The temperature variation of the drain current at a fixed bias shows both positive and negative resistance characteristics depending on the gate threshold voltage and gate-to source bias votage. In this paper, the decision method of the gate crossover voltage by the temperature variation and a new method to determine the gate threshold voltage graphecally are presented.

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Discontinuity of Representativeness Heuristic

  • 이호창
    • 경영과학
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    • 제16권1호
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    • pp.101-113
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    • 1999
  • The individual behavior on considering prior information when one assesses the probability of uncertain event by representativeness heuristic has been investigated. While prior researches proposed two contrasting behaviors on the employment, we tested the mixed hypothesis that individual ignores the prior information to some extents and begins to consider it above certain threshold when the evidence of representativeness is not salient. The threshold effect of prior probability is positively experimented and the results strongly support the discontinuity hypothesis of representativeness heuristic.

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Subthreshold Current Model of FinFET Using Three Dimensional Poisson's Equation

  • Jung, Hak-Kee
    • Journal of information and communication convergence engineering
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    • 제7권1호
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    • pp.57-61
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    • 2009
  • This paper has presented the subthreshold current model of FinFET using the potential variation in the doped channel based on the analytical solution of three dimensional Poisson's equation. The model has been verified by the comparison with the data from 3D numerical device simulator. The variation of subthreshold current with front and back gate bias has been studied. The variation of subthreshold swing and threshold voltage with front and back gate bias has been investigated.

Index-coupled DFB 레이저의 여러 가지 양 단면 반사율 조합에 따른 문턱 전류 이상에서 단일 모드 수율 해석 (Single mode yield analysis of index-coupled DFB lasers above threshold for various facet reflectivity combinations)

  • 김상택;전재두;김부균
    • 한국광학회지
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    • 제14권3호
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    • pp.298-305
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    • 2003
  • Index-coupled(IC) DFB 레이저에서 여러 가지 kL과 양 단면 반사율 조합에 대하여 문턱 전류 이상에서 주입 전류에 따른 단일 모드 수율을 구하였고 그 결과를 문턱 전류에서 f number에 따른 단일 모드 수율과의 관련성에 대하여 검토하였다. 그결과 문턱 전류 이상에서 단일 모드 수율과 문턱 전류에서 f number에 따른 단일 모드 수율과의 관련성이 매우 적음을 알수 있었다. 문턱 전류 이상에서 kL이 0.8과 1.25인 경우가 kL이 2와 3인 경우에 비하여 SHB 현상이 작아 단일 모드 수율이 큼을 알 수 있었다 또한 양 단면 반사율 조합이 AR-HR과 AR-CL에 대하여 AR 단면의 반사율이 단일 모드 수율에 미치는 영향에 대하여 살펴보았다. 양 단면 반사율 조합이 AR-HR인 경우 AR단면의 반사율이 작을수록 단일 모드 수율은 크게 나타났다. 반면에 AR-CL의 경우 최대의 단일 모드 수율을 나타내는 최적의 AR단면의 반사율이 존재하였다. 본 논문에서 수행한 IC DFB 레이저의 단일 모드 수율 계산에서는 kL이 0.8이고 양 단면 반사율 조합이 AR(1%)-HR인 경우가 문턱전류 이상에서 단일 모드 수율이 가장 컸다.

Optimization of Gate Stack MOSFETs with Quantization Effects

  • Mangla, Tina;Sehgal, Amit;Saxena, Manoj;Haldar, Subhasis;Gupta, Mridula;Gupta, R.S.
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제4권3호
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    • pp.228-239
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    • 2004
  • In this paper, an analytical model accounting for the quantum effects in MOSFETs has been developed to study the behaviour of $high-{\kappa}$ dielectrics and to calculate the threshold voltage of the device considering two dielectrics gate stack. The effect of variation in gate stack thickness and permittivity on surface potential, inversion layer charge density, threshold voltage, and $I_D-V_D$ characteristics have also been studied. This work aims at presenting a relation between the physical gate dielectric thickness, dielectric constant and substrate doping concentration to achieve targeted threshold voltage, together with minimizing the effect of gate tunneling current. The results so obtained are compared with the available simulated data and the other models available in the literature and show good agreement.

서울시의 기온변화와 사망자수 간의 관련성 연구 (The Relationships between Temperature Changes and Mortality in Seoul, Korea)

  • 이사라;김호;이승묵
    • 한국환경보건학회지
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    • 제36권1호
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    • pp.20-26
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    • 2010
  • Temperature change has been shown to affect daily mortality even though different analytical methods produce different results. The effect of air pollution on the relationship between the temperature and the mortality is not large, although differences exist between temperature models. The aim of this study was to examine how the temperature change affected the daily mortality in Seoul by comparing the results from the temperature model using two study periods: one from 1994 to 2007 and the other from 1997 to 2007. Generally mean temperature, minimum temperature and Q10 temperature was derived as an optimal model, even though there are differences between age and cause of death. The analysis of threshold using total mortalities in all ages from 1994 to 2007 and from 1997 to 2007 showed that the number of the deaths increased 7.02% (95% CI: 6.06~7.98) and 2.51% (95% CI: 1.83~3.19), respectively as the mean temperature increased $1^{\circ}C$ from a threshold temperature of $27.5^{\circ}C$ and $25.7^{\circ}C$ respectively. These results indicated that the temperature has less effect on the number of death than does an extreme heat wave period.

연속적 전기습윤 효과를 이용한 액체금속 액적의 채널 내 거동 (Movement of Liquid Metal Droplet in Channel by Continuous Electrowetting Effect)

  • 백승범;원동준;김호진;김준원
    • 한국정밀공학회지
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    • 제33권3호
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    • pp.217-223
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    • 2016
  • In this paper, the movement of a liquid metal droplet in a channel by continuous electrowetting effect is analyzed. The channel is fabricated using two glass substrates and silicone rubber as spacers, and a mercury droplet and dilute sulfuric acid are added into the channel. The droplet is moved according to voltage applied at both ends of the channel through an electrolyte. According to the shape of the droplet and the applied voltage, the velocity of the droplet is changed. The velocity is proportional to the applied voltage and inversely proportional to the length of the droplet, both theoretically and experimentally. Contact angle hysteresis and a meniscus change were also found in the moving state. This implies the existence of a threshold in movement by Laplace pressure difference. The experiment indicated that the sliding angle was inversely proportional to the width of the droplet but that the voltage threshold was proportional to the width.

Neuropathic pain을 일으킨 쥐에 있어서 침의 진통작용 (Acupuncture analgesia in a rat model of neuropathic pain)

  • 임규상
    • 한방안이비인후피부과학회지
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    • 제12권1호
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    • pp.143-153
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    • 1999
  • Background: The vasoreactivity of cerebral artery is currently the subject of increasing interest Transcranial Doppler The purpose of this study was to investigate the analgesic effect of acupuncture in a model of neuropathic pain produced by segmental spinal nerve injury (SSI) in rats. The left L5 and L6 spinal nerves of Sprague-Dawley rats were tightly ligated, and one week later, manual or electro-acupuncture was applied for 30 minutes to the contralateral hindlimb (right side) while the animal was lightly anesthetized with halothane. The mechanical threshold of the paw for ipsilateral (left side) hind limb flinching was determined prior to and 0.5, 1, 2, 4, and 24 hours after termination of acupuncture. The mechanical threshold for flinching was significantly elevated for about 4 hours after manual acupuncture applied to the BL. 60 (Kunlun) point or electro-acupuncture to the BL. 60 and BL. 40 (Weizhong) points. However, manual acupuncture applied to the ST. 36 (Zusanli) point was not effective. Furthermore, systemic naloxone pretreatment had no effect on the acupuncture induced threshold elevation. These data suggests that acupuncture produces a point specific, naloxone independent analgesia in a rat neuropathic pain model. ※ This paper is supported by a grant from the '1996 Jusan Foundation of Wonkwang university.)

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