• Journal of The Korean Association For Science Education
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• v.35 no.1
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• pp.159-167
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• 2015

RI-Biomics is a promising radiation convergence technology that combines radiation with bio science as new growth power technology. Many developed countries are focusing active support and constant exertion to dominate the RI-Biomics market in advance. In order to achieve global leadership in the RI-Biomics field, we need more highly advanced technologies and professional manpower. In fact, we have less manpower compared to technology we currently hold. In this study, we established a basic infrastructure to train professional manpower in the RI-Biomics field by developing/operating optimum training program through expert interviews and survey. The developed program has four organized sections to understand overall procedure of RI-Biomics. To evaluate our training program, we performed test operations with eight students who have a major related to RI-Biomics for three weeks in KARA (Seoul) and KAERI (Jung-eup). In detail, radioisotope usage and safety management were conducted for one week as basic course, RI-Biomics application technology was conducted for two weeks as professional course. To verify performance results of training program, we conducted to journal research, daily reports, and survey on participants. The results show a high level of satisfaction with training programs and continuous intention of involvement in our program. We also need to develop an intensive course to train high-quality human resources and to operate training program continuously. This training program will be used as basic materials for the development of RI-Biomics curriculum for university. Hence, we will expect that our training program contributes in training a professional manpower and develop RI-Biomics technology.

• IMMUNE NETWORK
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• v.4 no.1
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• pp.16-22
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• 2004

Background: To develop a novel treatment strategy for hepatitis B virus infection, a major cause of liver chirosis and cancer, we aimed to make human monoclonal antibodies inhibiting RNase H activity of P protein playing in important role in HBV replication. In this regard, phage display technology was employed and demonstrated as an efficient cloning method for human monoclonal antibody. So this study analysed the usability of human monoclonal antibody as protein based gene therapy. Methods: RNase H of HBV was expressed as fusion protein with maltose binding protein and purified with amylose resin column. Single chain Fv (scFv) phage antibody library was constructed by PCR cloning using total RNAs of PBMC from 50 healthy volunteers. Binders to RNase H were selected with BIAcore 2000 from the constructed library, and purified as soluble antibody fragment. The affinity and sequences of selected antibody fragments were analyzed with BIAcore and ABI automatic sequencer, respectively. And finally RNase H activity inhibiting assay was carried out. Results: Recombinant RNase H expressed in E. coli exhibited an proper enzyme activity. Naive library of $4.46{\times}10^9cfu$ was screened by BIAcore 2000. Two clones, RN41 and RN56, showed affinity of $4.5{\times}10^{-7}M$ and $1.9{\times}10^{-7}M$, respectively. But RNase H inhibiting activity of RN41 was higher than that of RN56. Conclusion: We cloned human monoclonal antibodies inhibiting RNase H activity of P protein of HBV. These antibodies can be expected to be a good candidate for protein-based antiviral therapy by preventing a replication of HBV if they can be expressed intracellularly in HBV-infected hepatocytes.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.45 no.2
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• pp.1-9
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• 2008

As the security requirements of mobile phones have been increasing, there have been extensive researches using one biometric feature (e.g., an iris, a fingerprint, or a face image) for authentication. Due to the limitation of uni-modal biometrics, we propose a method that combines face and iris images in order to improve accuracy in mobile environments. This paper presents four advantages and contributions over previous research. First, in order to capture both face and iris image at fast speed and simultaneously, we use a built-in conventional mega pixel camera in mobile phone, which is revised to capture the NIR (Near-InfraRed) face and iris image. Second, in order to increase the authentication accuracy of face and iris, we propose a score level fusion method based on SVM (Support Vector Machine). Third, to reduce the classification complexities of SVM and intra-variation of face and iris data, we normalize the input face and iris data, respectively. For face, a NIR illuminator and NIR passing filter on camera are used to reduce the illumination variance caused by environmental visible lighting and the consequent saturated region in face by the NIR illuminator is normalized by low processing logarithmic algorithm considering mobile phone. For iris, image transform into polar coordinate and iris code shifting are used for obtaining robust identification accuracy irrespective of image capturing condition. Fourth, to increase the processing speed on mobile phone, we use integer based face and iris authentication algorithms. Experimental results were tested with face and iris images by mega-pixel camera of mobile phone. It showed that the authentication accuracy using SVM was better than those of uni-modal (face or iris), SUM, MAX, NIN and weighted SUM rules.

• Archives of design research
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• v.17 no.2
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• pp.181-188
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• 2004

The values of material civilizations that dominated the last century have been replaced with invisible values such as knowledge, information, and culture. The central axis of the world economy is also rapidly shifting from a capital and labor-intensive industry to a knowledge-based industry of software and contents. From the perspective of the industrialization of culture as multinational corporations and dominance and subordination relationships between cultures thereof, and crisis of cultural identity, the issues of support and fostering a culture industry arise. These have become major issues of concern in deciding national policies. In response to this trend, new departments related to culture contents in various universities have been established for fostering manpower in the field and the government policy to foster related human resources. However, actual results have not been currently achieved, despite the increase in quantity. This is due to the fact that the walls between culture contents departments were too high and thus education and fostering excellent human resources have not been properly conducted. It is also due to the obscure direction of education and a deficiency in the system. To cope with these problems, a systematic manpower-fostering education program should be developed through enhancement of the understanding of culture contents via linking education programs with detailed major fields of study. Accordingly, this study aims to identify changes in the current culture contents industry at home and abroad according to digitalization for fostering manpower of culture contents required in a rapidly changing environment of the culture contents industry. Then, it will review what influence has been made on the education system through the identification of personnel types through work flow charts and contents delivery modes following integration, as well as a desirable method to construct culture contents. Therefore, this study is a preliminary study on the means of fostering core personnel in the culture contents industry through linkage with the education system.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.10
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• pp.610-616
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• 2018

A variety of creative convergence education studies have been conducted around the world, but the study of creative convergence education based on problem-oriented learning is insignificant. STEAM education development research for engineering human resources also recognizes important factors like ethics awareness and consideration, cooperation, leadership, and communication skills. This study developed a model of interdisciplinary classes between marketing and commercial English classes as a way to effectively learn to cultivate the creative and fusion talents required by modern society. A model was developed for the process of convergence classes to be developed for evaluation after class by designing courses, selecting subjects, designing classes, drawing questions, and developing problems, as well as for discussion of pre-convergence courses, class performance, and class evaluation. The Mongolian university discussed in this paper plans to introduce a suitable educational environment by developing a problem for interdisciplinary classes in marketing and business English. Based on the need to nurture talent required by the rapidly changing knowledge-based society, Mongolian universities should continue the strategy of fostering creative convergence talent through the convergence of technology. This is because creativity is the most important thing in the current situation.

• Journal of Korean Ophthalmic Optics Society
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• v.18 no.2
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• pp.203-211
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• 2013

Purpose: When we look at the object, we used the dominant eye mainly. For this reason, a prescription of the dominant eye is an important factor for glasses and contact lenses. This study evaluated visual acuity differences between dominant and nondominant eyes through analyzing refractive power changes in both eyes by the ages. Methods: This study was performed to investigate the relationship between refractive error and dominant eye which had the superiority in the function of binocular. 186 subjects without ocular disease were examined on the dominant eye. The dominant eye was examined by the Hole-in-the-card test. For the consistency of the measurements, we tested refractive power in three times by the same person. Results: Using SPSS, the relationship between vision and the dominant eye was analyzed. 135 people of the whole subjects have the dominant eye on right. The Number of the non-dominant eye is 51. We were divided into 3 types, the group under the age of 10 that begins to expose environment factor affect on vision (the average age $8.8{\pm}1.18$) and the age group of 10 to 20 that begins to change refractive power in earnest (the average age $14.1{\pm}2.58$) and the group after the age 20 that began to stabilize vision (the average age $51.8{\pm}17.51$). The visual acuity of dominant eye was higher than non-dominant eye in all age groups. Nevertheless, these results were not statistically significant. Mean astigmatism of dominant eye was smaller than the non-dominant eye, and this is significant, statistically (p=0.017<0.05). Conclusions: It is expected that the balanced eye with a lower level of astigmatism has a more possibility become a dominant eye.

• Journal of Convergence for Information Technology
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• v.8 no.1
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• pp.79-87
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• 2018

The purpose of this study was to investigate the relationships among psychological, emotional variables related to the career indecision of college students and to present effective action strategies by searching basic data that can prevent college students from undeciding their career path. In this study, we analyzed the relationship between the variables related to career indecision of college students and the structural equation model to verify the fit of the research model. The results of this study suggest that adaptive perfectionism has a positive effect on career decision self-efficacy and career decision self-efficacy has a negative effect on career indecision and adaptive perfectionism has a negative effect on career indecision by mediating career decision self-efficacy. In addition, maladaptive perfectionism has a negative effect on career decision self-efficacy, and it has a positive effect on career indecision through mediation of career decision self-efficacy. we discussed the implications for career decision making and employment of college students based on the results of the relationship between variables such as perfectionism, career decision self-efficacy, and career indecision.

• Journal of the East Asian Society of Dietary Life
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• v.19 no.2
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• pp.180-186
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• 2009

In this study, Crotalaria sessiliflora L., leaf was extracted with a solvent mixture of $CH_2Cl_2$ and $CH_2OH$ (3:1). In order to draw or separate effective components from the leaf extract with high activity, a 1:1 solvent mixture of water and butanol was used after removal of the sugar and fat from the extract. From the decompressed and concentrated butanol layer, 10 small fractions (Fr1, Fr2, Fr3, Fr4, Fr5, Fr6, Fr7, Fr8, Fr9, and Fr10) were obtained using a chromatography column filled with sephadex LH-20. The activity of each fraction was measured by the same method as that used to measure the antioxidant effect of each part(p<0.05). The Fr1, Fr4, and Fr6 fractions showed the highest activity levels(p<0.05). The vital unknown material that vitality exists in the strong butanol fractions of F1, F4 and F6 will be isolated and identified. Currently, we are performing for a single compound from an unknown peak by instrumental analysis.

• Spatial Information Research
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• v.21 no.5
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• pp.43-51
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• 2013

In this study, the concept of spatial big data and effective ways to build a spatial big data system are presented. Big Data is defined as 3V(volume, variety, velocity). Spatial big data is the basis for evolution from 3V's big data to 6V's big data(volume, variety, velocity, value, veracity, visualization). In order to build an effective spatial big data, spatial big data system building should be promoted. In addition, spatial big data system should be performed a national spatial information base, convergence platform, service providers, and providers as a factor of production. The spatial big data system is made up of infrastructure(hardware), technology (software), spatial big data(data), human resources, law etc. The goals for the spatial big data system build are spatial-based policy support, spatial big data platform based industries enable, spatial big data fusion-based composition, spatial active in social issues. Strategies for achieving the objectives are build the government-wide cooperation, new industry creation and activation, and spatial big data platform built, technologies competitiveness of spatial big data.

• Journal of the Korea Society of Computer and Information
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• v.19 no.1
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• pp.95-110
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• 2014

The purpose of this research is to further investigate the influence of partnership between with the mediator effect of the social business on the outcome of SCM. IT technology fusion electronic tags, mobile phone, such as cloud computing is also activated in supply chain management of recently, business is faster, if social business is applied here that are smarter, customers or suppliers, there may be communication directly and to further improve the relationship partnership. 150 questionnaires were sent to companies that have introduced SCM to their systems and are operating it. Among 150 questionnaires, 127 collected data were analyzed excluding incomplete 23 data. Statistical methods used in this study were frequency analysis, factor analysis, reliability analysis, t-test, ANOVA, path analysis, Scheffe test and Sobel test with Amos 18.0. and SPSS 21.0. The analytical results are as follows. First, the more the reliability, information share, continuous transaction, effects on the social business are getting higher, the interdependence has little impact on it. Second, the impact on the outcome of SCM, partnerships between companies, showed a significant influence the reliability, the share of information, the continuous transaction, but the interdependence was analysed as an uninfluential factor. Third, the social business is analyses to have a mediator effect in relationship between the partnership and the outcome of SCM.